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Quinolones Global Market Report 2024

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    Report

  • 200 Pages
  • January 2024
  • Region: Global
  • The Business Research Company
  • ID: 5793013
The quinolones market size has grown steadily in recent years. It will grow from $48.31 billion in 2023 to $50.65 billion in 2024 at a compound annual growth rate (CAGR) of 4.9%. The growth observed in the historical period can be attributed to factors such as the demand for antibiotics and their usage, regulatory approvals, research and development activities, the competitive landscape within the pharmaceutical industry, and the expiration of patents.

The quinolones market size is expected to see steady growth in the next few years. It will grow to $61.51 billion in 2028 at a compound annual growth rate (CAGR) of 5.0%. The anticipated growth in the forecast period can be attributed to factors such as the emergence of new diseases, regulatory changes, global health policies, the increasing challenge of antibiotic resistance, and market expansion strategies. Key trends expected in the forecast period may include advancements or shifts in medical research, changes in healthcare policies, and evolving strategies to address antibiotic resistance.

The growth of the quinolones market is significantly attributed to the increasing incidence of infectious diseases. Infectious diseases, caused by microbes such as parasites, fungi, bacteria, and viruses, remain a global health challenge. Quinolones, widely employed in treating various bacterial infections such as tuberculosis and urinary tract infections, play a crucial role in addressing these health concerns. For example, data from 2022 provided by the Pan American Health Organization indicated that approximately 10.6 million people contracted tuberculosis (TB) in 2021, marking a 4.5% increase. Thus, the upsurge in infectious diseases is a driving force behind the growth of the quinolones market.

The anticipated rise in antimicrobial resistance contributes to the continued growth of the quinolones market. Antimicrobial resistance (AMR), the ability of microorganisms to resist the effects of antimicrobial drugs, poses a significant threat to public health. Quinolones, with their broad spectrum of activity and effectiveness against various bacteria, become a preferred choice in cases of limited options. Notably, in November 2022, the United Kingdom Health Security Agency reported a 2.2% increase in the predicted total number of severe antibiotic-resistant infections in England in 2021. This highlights the growing danger of antimicrobial resistance, which is propelling the demand for quinolones.

A prominent trend in the quinolones market is the emphasis on product innovation by major companies to sustain their market positions. For instance, in January 2023, Viatris, a US-based pharmaceutical company's South Korean branch introduced Dovprela, a novel treatment for drug-resistant tuberculosis. Dovprela, a three-drug regimen comprising bedaquiline, pretomanid, and linezolid (BPaL), offers a more rapid anti-tuberculosis effect, reducing the treatment period from 18-20 months to 5-6 months. This innovation addresses the pressing need for effective and efficient tuberculosis treatments.

Innovative products, such as fluoroquinolone antibiotic eye drops, are being introduced to drive revenues in the quinolones market. Fluoroquinolone antibiotic eye drops, a class of antibiotics targeting bacterial eye infections, contribute to ophthalmic health. For instance, Harrow Health Inc., a US-based pharmaceutical company, launched Vigamox in July 2023. This sterile ophthalmic solution, delivered in a 3-milliliter bottle, is indicated for the prevention of eye infections before and after surgery. Such innovative products cater to diverse medical needs and contribute to the market's growth.

In June 2023, Bausch + Lomb Incorporated, a US-based eye health company, acquired Novartis International AG for an undisclosed amount. Through this acquisition, Bausch + Lomb aims to restructure its pharmaceutical division, enhancing its scale and positioning it at the forefront of addressing ocular surface disorders. The acquisition diversifies Bausch + Lomb's product portfolio, introducing new opportunities such as libvatrep and AcuStream technology. Libvatrep is an experimental compound studied for treating chronic ocular surface pain, while AcuStream technology is an experimental device designed for accurate dosing and delivery of certain topical ophthalmic medications. Novartis International AG, based in Switzerland, is a pharmaceutical company with a global presence.

Major companies operating in the quinolones market report are Bayer AG, Novartis AG, Sanofi SA, Johnson & Johnson Services Inc., Merck & Co. Inc., LG Life Sciences, Allergan Inc., Pfizer Inc., Viatris Inc., Lupin Limited, Hikma Pharmaceuticals plc, Zydus Group, Bausch Health Companies Inc., KYORIN Holdings Inc., MerLion Pharmaceuticals GmbH, Teva Pharmaceutical Industries Ltd., GSK plc, AbbVie Inc., Zee Laboratories, Cipla Ltd., Bhavishya Pharmaceuticals, Geo Pharma Pvt. Ltd., Finecure Pharmaceuticals, Novus, AstraZeneca plc, Sun Pharmaceutical Industries Ltd., Dr. Reddy's Laboratories Ltd., Cadila Healthcare Ltd., Glenmark Pharmaceuticals Ltd., Alkem Laboratories Ltd., Torrent Pharmaceuticals Ltd., Macleods Pharmaceuticals Ltd., Alembic Pharmaceuticals Ltd., Hetero Drugs Ltd., Mylan N.V., Wockhardt Ltd.

North America was the largest region in the quinolones market in 2023. The regions covered in the quinolones market report are Asia-Pacific, Western Europe, Eastern Europe, North America, South America, Middle East, Africa. The countries covered in the quinolones market report are Australia, Brazil, China, France, Germany, India, Indonesia, Japan, Russia, South Korea, UK, USA, Canada, Italy, Spain.

The primary types of quinolones include norfloxacin, ofloxacin, ciprofloxacin, gemifloxacin, and others. Norfloxacin, specifically a fluoroquinolone, is utilized for the treatment of diverse bacterial infections. Its applications extend to addressing conditions such as conjunctivitis and urinary tract infections, targeting both gram-positive and gram-negative pathogens. Quinolones are distributed through various channels, including hospital pharmacies, retail pharmacies, and online pharmacies.

The quinolones market research report is one of a series of new reports that provides, quinolones market statistics, including, quinolones industry global market size, regional shares, competitors with a quinolones market share, detailed, quinolones market segments, market trends and opportunities, and any further data you may need to thrive in the quinolones industry. This, quinolones market research report delivers a complete perspective of everything you need, with an in-depth analysis of the current and future scenario of the industry.

The market value is defined as the revenues that enterprises gain from the sale of goods and/or services within the specified market and geography through sales, grants, or donations in terms of the currency (in USD, unless otherwise specified).

The revenues for a specified geography are consumption values that are revenues generated by organizations in the specified geography within the market, irrespective of where they are produced. It does not include revenues from resales along the supply chain, either further along the supply chain or as part of other products.


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Table of Contents

1. Executive Summary2. Quinolones Market Characteristics3. Quinolones Market Trends and Strategies
4. Quinolones Market - Macro Economic Scenario
4.1. Impact of High Inflation on the Market
4.2. Ukraine-Russia War Impact on the Market
4.3. COVID-19 Impact on the Market
5. Global Quinolones Market Size and Growth
5.1. Global Quinolones Market Drivers and Restraints
5.1.1. Drivers of the Market
5.1.2. Restraints of the Market
5.2. Global Quinolones Historic Market Size and Growth, 2018-2023, Value ($ Billion)
5.3. Global Quinolones Forecast Market Size and Growth, 2023-2028, 2033F, Value ($ Billion)
6. Quinolones Market Segmentation
6.1. Global Quinolones Market, Segmentation by Type, Historic and Forecast, 2018-2023, 2023-2028F, 2033F, $ Billion
  • Norfloxacin
  • Ofloxacin
  • Ciprofloxacin
  • Gemifloxacin
  • Other Types
6.2. Global Quinolones Market, Segmentation by Pathogen Type, Historic and Forecast, 2018-2023, 2023-2028F, 2033F, $ Billion
  • Gram-Positive Pathogen
  • Gram-Negative Pathogen
6.3. Global Quinolones Market, Segmentation by Application, Historic and Forecast, 2018-2023, 2023-2028F, 2033F, $ Billion
  • Hospital Pharmacies
  • Retail Pharmacies
  • Online Pharmacies
7. Quinolones Market Regional and Country Analysis
7.1. Global Quinolones Market, Split by Region, Historic and Forecast, 2018-2023, 2023-2028F, 2033F, $ Billion
7.2. Global Quinolones Market, Split by Country, Historic and Forecast, 2018-2023, 2023-2028F, 2033F, $ Billion
8. Asia-Pacific Quinolones Market
8.1. Asia-Pacific Quinolones Market Overview
Region Information, Impact of COVID-19, Market Information, Background Information, Government Initiatives, Regulations, Regulatory Bodies, Major Associations, Taxes Levied, Corporate Tax Structure, Investments, Major Companies
8.2. Asia-Pacific Quinolones Market, Segmentation by Type, Historic and Forecast, 2018-2023, 2023-2028F, 2033F, $ Billion
8.3. Asia-Pacific Quinolones Market, Segmentation by Pathogen Type, Historic and Forecast, 2018-2023, 2023-2028F, 2033F, $ Billion
8.4. Asia-Pacific Quinolones Market, Segmentation by Application, Historic and Forecast, 2018-2023, 2023-2028F, 2033F, $ Billion
9. China Quinolones Market
9.1. China Quinolones Market Overview
9.2. China Quinolones Market, Segmentation by Type, Historic and Forecast, 2018-2023, 2023-2028F, 2033F,$ Billion
9.3. China Quinolones Market, Segmentation by Pathogen Type, Historic and Forecast, 2018-2023, 2023-2028F, 2033F,$ Billion
9.4. China Quinolones Market, Segmentation by Application, Historic and Forecast, 2018-2023, 2023-2028F, 2033F,$ Billion
10. India Quinolones Market
10.1. India Quinolones Market, Segmentation by Type, Historic and Forecast, 2018-2023, 2023-2028F, 2033F, $ Billion
10.2. India Quinolones Market, Segmentation by Pathogen Type, Historic and Forecast, 2018-2023, 2023-2028F, 2033F, $ Billion
10.3. India Quinolones Market, Segmentation by Application, Historic and Forecast, 2018-2023, 2023-2028F, 2033F, $ Billion
11. Japan Quinolones Market
11.1. Japan Quinolones Market Overview
11.2. Japan Quinolones Market, Segmentation by Type, Historic and Forecast, 2018-2023, 2023-2028F, 2033F, $ Billion
11.3. Japan Quinolones Market, Segmentation by Pathogen Type, Historic and Forecast, 2018-2023, 2023-2028F, 2033F, $ Billion
11.4. Japan Quinolones Market, Segmentation by Application, Historic and Forecast, 2018-2023, 2023-2028F, 2033F, $ Billion
12. Australia Quinolones Market
12.1. Australia Quinolones Market, Segmentation by Type, Historic and Forecast, 2018-2023, 2023-2028F, 2033F, $ Billion
12.2. Australia Quinolones Market, Segmentation by Pathogen Type, Historic and Forecast, 2018-2023, 2023-2028F, 2033F, $ Billion
12.3. Australia Quinolones Market, Segmentation by Application, Historic and Forecast, 2018-2023, 2023-2028F, 2033F, $ Billion
13. Indonesia Quinolones Market
13.1. Indonesia Quinolones Market, Segmentation by Type, Historic and Forecast, 2018-2023, 2023-2028F, 2033F, $ Billion
13.2. Indonesia Quinolones Market, Segmentation by Pathogen Type, Historic and Forecast, 2018-2023, 2023-2028F, 2033F, $ Billion
13.3. Indonesia Quinolones Market, Segmentation by Application, Historic and Forecast, 2018-2023, 2023-2028F, 2033F, $ Billion
14. South Korea Quinolones Market
14.1. South Korea Quinolones Market Overview
14.2. South Korea Quinolones Market, Segmentation by Type, Historic and Forecast, 2018-2023, 2023-2028F, 2033F, $ Billion
14.3. South Korea Quinolones Market, Segmentation by Pathogen Type, Historic and Forecast, 2018-2023, 2023-2028F, 2033F, $ Billion
14.4. South Korea Quinolones Market, Segmentation by Application, Historic and Forecast, 2018-2023, 2023-2028F, 2033F, $ Billion
15. Western Europe Quinolones Market
15.1. Western Europe Quinolones Market Overview
15.2. Western Europe Quinolones Market, Segmentation by Type, Historic and Forecast, 2018-2023, 2023-2028F, 2033F, $ Billion
15.3. Western Europe Quinolones Market, Segmentation by Pathogen Type, Historic and Forecast, 2018-2023, 2023-2028F, 2033F, $ Billion
15.4. Western Europe Quinolones Market, Segmentation by Application, Historic and Forecast, 2018-2023, 2023-2028F, 2033F, $ Billion
16. UK Quinolones Market
16.1. UK Quinolones Market, Segmentation by Type, Historic and Forecast, 2018-2023, 2023-2028F, 2033F, $ Billion
16.2. UK Quinolones Market, Segmentation by Pathogen Type, Historic and Forecast, 2018-2023, 2023-2028F, 2033F, $ Billion
16.3. UK Quinolones Market, Segmentation by Application, Historic and Forecast, 2018-2023, 2023-2028F, 2033F, $ Billion
17. Germany Quinolones Market
17.1. Germany Quinolones Market, Segmentation by Type, Historic and Forecast, 2018-2023, 2023-2028F, 2033F, $ Billion
17.2. Germany Quinolones Market, Segmentation by Pathogen Type, Historic and Forecast, 2018-2023, 2023-2028F, 2033F, $ Billion
17.3. Germany Quinolones Market, Segmentation by Application, Historic and Forecast, 2018-2023, 2023-2028F, 2033F, $ Billion
18. France Quinolones Market
18.1. France Quinolones Market, Segmentation by Type, Historic and Forecast, 2018-2023, 2023-2028F, 2033F, $ Billion
18.2. France Quinolones Market, Segmentation by Pathogen Type, Historic and Forecast, 2018-2023, 2023-2028F, 2033F, $ Billion
18.3. France Quinolones Market, Segmentation by Application, Historic and Forecast, 2018-2023, 2023-2028F, 2033F, $ Billion
19. Italy Quinolones Market
19.1. Italy Quinolones Market, Segmentation by Type, Historic and Forecast, 2018-2023, 2023-2028F, 2033F, $ Billion
19.2. Italy Quinolones Market, Segmentation by Pathogen Type, Historic and Forecast, 2018-2023, 2023-2028F, 2033F, $ Billion
19.3. Italy Quinolones Market, Segmentation by Application, Historic and Forecast, 2018-2023, 2023-2028F, 2033F, $ Billion
20. Spain Quinolones Market
20.1. Spain Quinolones Market, Segmentation by Type, Historic and Forecast, 2018-2023, 2023-2028F, 2033F, $ Billion
20.2. Spain Quinolones Market, Segmentation by Pathogen Type, Historic and Forecast, 2018-2023, 2023-2028F, 2033F, $ Billion
20.3. Spain Quinolones Market, Segmentation by Application, Historic and Forecast, 2018-2023, 2023-2028F, 2033F, $ Billion
21. Eastern Europe Quinolones Market
21.1. Eastern Europe Quinolones Market Overview
21.2. Eastern Europe Quinolones Market, Segmentation by Type, Historic and Forecast, 2018-2023, 2023-2028F, 2033F, $ Billion
21.3. Eastern Europe Quinolones Market, Segmentation by Pathogen Type, Historic and Forecast, 2018-2023, 2023-2028F, 2033F, $ Billion
21.4. Eastern Europe Quinolones Market, Segmentation by Application, Historic and Forecast, 2018-2023, 2023-2028F, 2033F, $ Billion
22. Russia Quinolones Market
22.1. Russia Quinolones Market, Segmentation by Type, Historic and Forecast, 2018-2023, 2023-2028F, 2033F, $ Billion
22.2. Russia Quinolones Market, Segmentation by Pathogen Type, Historic and Forecast, 2018-2023, 2023-2028F, 2033F, $ Billion
22.3. Russia Quinolones Market, Segmentation by Application, Historic and Forecast, 2018-2023, 2023-2028F, 2033F, $ Billion
23. North America Quinolones Market
23.1. North America Quinolones Market Overview
23.2. North America Quinolones Market, Segmentation by Type, Historic and Forecast, 2018-2023, 2023-2028F, 2033F, $ Billion
23.3. North America Quinolones Market, Segmentation by Pathogen Type, Historic and Forecast, 2018-2023, 2023-2028F, 2033F, $ Billion
23.4. North America Quinolones Market, Segmentation by Application, Historic and Forecast, 2018-2023, 2023-2028F, 2033F, $ Billion
24. USA Quinolones Market
24.1. USA Quinolones Market Overview
24.2. USA Quinolones Market, Segmentation by Type, Historic and Forecast, 2018-2023, 2023-2028F, 2033F, $ Billion
24.3. USA Quinolones Market, Segmentation by Pathogen Type, Historic and Forecast, 2018-2023, 2023-2028F, 2033F, $ Billion
24.4. USA Quinolones Market, Segmentation by Application, Historic and Forecast, 2018-2023, 2023-2028F, 2033F, $ Billion
25. Canada Quinolones Market
25.1. Canada Quinolones Market Overview
25.2. Canada Quinolones Market, Segmentation by Type, Historic and Forecast, 2018-2023, 2023-2028F, 2033F, $ Billion
25.3. Canada Quinolones Market, Segmentation by Pathogen Type, Historic and Forecast, 2018-2023, 2023-2028F, 2033F, $ Billion
25.4. Canada Quinolones Market, Segmentation by Application, Historic and Forecast, 2018-2023, 2023-2028F, 2033F, $ Billion
26. South America Quinolones Market
26.1. South America Quinolones Market Overview
26.2. South America Quinolones Market, Segmentation by Type, Historic and Forecast, 2018-2023, 2023-2028F, 2033F, $ Billion
26.3. South America Quinolones Market, Segmentation by Pathogen Type, Historic and Forecast, 2018-2023, 2023-2028F, 2033F, $ Billion
26.4. South America Quinolones Market, Segmentation by Application, Historic and Forecast, 2018-2023, 2023-2028F, 2033F, $ Billion
27. Brazil Quinolones Market
27.1. Brazil Quinolones Market, Segmentation by Type, Historic and Forecast, 2018-2023, 2023-2028F, 2033F, $ Billion
27.2. Brazil Quinolones Market, Segmentation by Pathogen Type, Historic and Forecast, 2018-2023, 2023-2028F, 2033F, $ Billion
27.3. Brazil Quinolones Market, Segmentation by Application, Historic and Forecast, 2018-2023, 2023-2028F, 2033F, $ Billion
28. Middle East Quinolones Market
28.1. Middle East Quinolones Market Overview
28.2. Middle East Quinolones Market, Segmentation by Type, Historic and Forecast, 2018-2023, 2023-2028F, 2033F, $ Billion
28.3. Middle East Quinolones Market, Segmentation by Pathogen Type, Historic and Forecast, 2018-2023, 2023-2028F, 2033F, $ Billion
28.4. Middle East Quinolones Market, Segmentation by Application, Historic and Forecast, 2018-2023, 2023-2028F, 2033F, $ Billion
29. Africa Quinolones Market
29.1. Africa Quinolones Market Overview
29.2. Africa Quinolones Market, Segmentation by Type, Historic and Forecast, 2018-2023, 2023-2028F, 2033F, $ Billion
29.3. Africa Quinolones Market, Segmentation by Pathogen Type, Historic and Forecast, 2018-2023, 2023-2028F, 2033F, $ Billion
29.4. Africa Quinolones Market, Segmentation by Application, Historic and Forecast, 2018-2023, 2023-2028F, 2033F, $ Billion
30. Quinolones Market Competitive Landscape and Company Profiles
30.1. Quinolones Market Competitive Landscape
30.2. Quinolones Market Company Profiles
30.2.1. Bayer AG
30.2.1.1. Overview
30.2.1.2. Products and Services
30.2.1.3. Strategy
30.2.1.4. Financial Performance
30.2.2. Novartis AG
30.2.2.1. Overview
30.2.2.2. Products and Services
30.2.2.3. Strategy
30.2.2.4. Financial Performance
30.2.3. Sanofi SA
30.2.3.1. Overview
30.2.3.2. Products and Services
30.2.3.3. Strategy
30.2.3.4. Financial Performance
30.2.4. Johnson & Johnson Services Inc.
30.2.4.1. Overview
30.2.4.2. Products and Services
30.2.4.3. Strategy
30.2.4.4. Financial Performance
30.2.5. Merck & Co. Inc.
30.2.5.1. Overview
30.2.5.2. Products and Services
30.2.5.3. Strategy
30.2.5.4. Financial Performance
31. Global Quinolones Market Competitive Benchmarking32. Global Quinolones Market Competitive Dashboard33. Key Mergers and Acquisitions in the Quinolones Market
34. Quinolones Market Future Outlook and Potential Analysis
34.1 Quinolones Market in 2028 - Countries Offering Most New Opportunities
34.2 Quinolones Market in 2028 - Segments Offering Most New Opportunities
34.3 Quinolones Market in 2028 - Growth Strategies
34.3.1 Market Trend Based Strategies
34.3.2 Competitor Strategies
35. Appendix
35.1. Abbreviations
35.2. Currencies
35.3. Historic and Forecast Inflation Rates
35.4. Research Inquiries
35.5. About the Analyst
35.6. Copyright and Disclaimer

Executive Summary

Quinolones Global Market Report 2024 provides strategists, marketers and senior management with the critical information they need to assess the market.

This report focuses on quinolones market which is experiencing strong growth. The report gives a guide to the trends which will be shaping the market over the next ten years and beyond.

Reasons to Purchase

  • Gain a truly global perspective with the most comprehensive report available on this market covering 50+ geographies.
  • Understand how the market has been affected by the COVID-19 and how it is responding as the impact of the virus abates.
  • Assess the Russia-Ukraine war’s impact on agriculture, energy and mineral commodity supply and its direct and indirect impact on the market.
  • Measure the impact of high global inflation on market growth.
  • Create regional and country strategies on the basis of local data and analysis.
  • Identify growth segments for investment.
  • Outperform competitors using forecast data and the drivers and trends shaping the market.
  • Understand customers based on the latest market shares.
  • Benchmark performance against key competitors.
  • Suitable for supporting your internal and external presentations with reliable high quality data and analysis
  • All data from the report will also be delivered in an excel dashboard format.

Description

Where is the largest and fastest growing market for quinolones? How does the market relate to the overall economy, demography and other similar markets? What forces will shape the market going forward? This quinolones market global report answers all of these questions and many more.

The report covers market characteristics, size and growth, segmentation, regional and country breakdowns, competitive landscape, market shares, trends and strategies for this market. It traces the market’s historic and forecast market growth by geography.

Scope

Markets Covered:

1) By Type: Norfloxacin; Ofloxacin; Ciprofloxacin; Gemifloxacin; Other Types

2) By Pathogen Type: Gram-Positive Pathogen; Gram-Negative Pathogen

3) By Application: Hospital Pharmacies; Retail Pharmacies; Online Pharmacies

Companies Mentioned: Bayer AG; Novartis AG; Sanofi SA; Johnson & Johnson Services Inc.; Merck & Co. Inc.

Countries: Australia; Brazil; China; France; Germany; India; Indonesia; Japan; Russia; South Korea; UK; USA; Canada; Italy; Spain

Regions: Asia-Pacific; Western Europe; Eastern Europe; North America; South America; Middle East; Africa

Time series: Five years historic and ten years forecast.

Data: Ratios of market size and growth to related markets, GDP proportions, expenditure per capita,

Data segmentations: country and regional historic and forecast data, market share of competitors, market segments.

Sourcing and Referencing: Data and analysis throughout the report is sourced using end notes.

Delivery format: PDF, Word and Excel Data Dashboard.

Companies Mentioned (Partial List)

A selection of companies mentioned in this report includes, but is not limited to:

  • Bayer AG
  • Novartis AG
  • Sanofi SA
  • Johnson & Johnson Services Inc.
  • Merck & Co. Inc.
  • LG Life Sciences
  • Allergan Inc.
  • Pfizer Inc.
  • Viatris Inc.
  • Lupin Limited
  • Hikma Pharmaceuticals plc
  • Zydus Group
  • Bausch Health Companies Inc.
  • KYORIN Holdings Inc.
  • MerLion Pharmaceuticals GmbH
  • Teva Pharmaceutical Industries Ltd.
  • GSK plc
  • AbbVie Inc.
  • Zee Laboratories
  • Cipla Ltd.
  • Bhavishya Pharmaceuticals
  • Geo Pharma Pvt. Ltd.
  • Finecure Pharmaceuticals
  • Novus
  • AstraZeneca plc
  • Sun Pharmaceutical Industries Ltd.
  • Dr. Reddy's Laboratories Ltd.
  • Cadila Healthcare Ltd.
  • Glenmark Pharmaceuticals Ltd.
  • Alkem Laboratories Ltd.
  • Torrent Pharmaceuticals Ltd.
  • Macleods Pharmaceuticals Ltd.
  • Alembic Pharmaceuticals Ltd.
  • Hetero Drugs Ltd.
  • Mylan N.V.
  • Wockhardt Ltd.

Methodology

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