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Global Idiopathic Pulmonary Fibrosis Treatment Market Report and Forecast 2023-2031

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    Report

  • 160 Pages
  • May 2023
  • Region: Global
  • Expert Market Research
  • ID: 5797957
The global idiopathic pulmonary fibrosis treatment market size attained a value of USD 3.39 billion in 2022. The market is anticipated to grow at a CAGR of 5.8% during the forecast period of 2023-2031 to attain a value of USD 5.6 billion by 2031.

Idiopathic Pulmonary Fibrosis Treatment Market: Introduction

Idiopathic pulmonary fibrosis (IPF) is a chronic, progressive lung disease characterized by the scarring (fibrosis) of the lungs. This scarring thickens and stiffens the lung tissue, leading to a steady decline in lung function, difficulty breathing, and a decreased ability for the lungs to deliver oxygen to the body's tissues.

As the name suggests, the cause of IPF is 'idiopathic', meaning it is unknown. However, certain risk factors are associated with the development of the disease. These include:

  • Age: IPF is more common in adults over 60 years of age
  • Gender: Men are more likely than women to develop the disease
  • Smoking: A history of smoking is a significant risk factor for IPF
  • Environmental Factors: Exposure to certain environmental pollutants, including dusts from metal, wood, coal, and silica, may increase the risk of IPF
  • Genetic Factors: Having a close relative with IPF suggests that genetic factors may play a role in the disease
While the exact process that leads to IPF is not completely understood, it is thought to involve an abnormal response to lung injury. Instead of the normal process of repair, the body responds with an overproduction of collagen and other proteins which lead to fibrosis. Over time, this fibrosis can worsen, leading to the progressive symptoms associated with the disease.

IPF is usually diagnosed through a combination of medical history, physical examination, pulmonary function tests, high-resolution computed tomography (HRCT) scans, and sometimes lung biopsy. It's a serious condition with a variable course, but it generally progresses over time. Treatment often involves managing symptoms, slowing disease progression, and improving quality of life. As of my knowledge cutoff in September 2021, there's no cure for IPF, but therapies like antifibrotic drugs, oxygen therapy, pulmonary rehabilitation, and in severe cases, lung transplantation, may be used.

Idiopathic Pulmonary Fibrosis Epidemiology
The epidemiology of idiopathic pulmonary fibrosis (IPF) varies globally and is influenced by factors such as prevalence, age, gender, and lifestyle habits.
  • Prevalence: The prevalence of IPF varies around the world, partly due to differences in diagnostic criteria and the challenges of diagnosing the disease. Estimates suggest that the disease may affect about 14 to 43 per 100,000 people in the general population. However, the true prevalence may be higher due to underdiagnosis
  • Age: IPF is primarily a disease of older adults. The incidence and prevalence of IPF increase with age, with most people being diagnosed between the ages of 50 and 70. This reflects the disease's progressive nature and the potential role of cumulative exposure to environmental risk factors and age-related changes in lung physiology
  • Gender: Men are more likely to be diagnosed with IPF than women. The reasons for this gender difference are not entirely understood but may involve hormonal factors, occupational exposures, or differences in smoking habits
  • Lifestyle Habits: Certain lifestyle factors have been associated with an increased risk of IPF. Smoking is the most well-established risk factor, with current or former smokers having a significantly higher risk of IPF than non-smokers. Occupational and environmental exposures to dusts (such as metal dust, wood dust, and coal dust) and certain types of fumes can also increase the risk of IPF
The geographic distribution of IPF also suggests a role for regional or environmental factors in the disease's epidemiology. For example, studies have found higher rates of IPF in certain regions, which could reflect local differences in risk factors such as environmental exposures or genetic factors.

Given the progressive and often rapid course of IPF, there is a need for early and accurate diagnosis, as well as effective treatments to slow disease progression. Understanding the epidemiology of IPF can help identify at-risk populations and guide research into the disease's causes and potential treatments.

Idiopathic Pulmonary Fibrosis Treatment Market Segmentations

The market can be categorised into drug class, marketed drugs, route of administration, drug type, treatment channel, end user, distribution channel, and region

Idiopathic Pulmonary Fibrosis Market Breakup by Drug class

  • Tyrosine Inhibitors,
  • MAPK Inhibitors
  • Autotaxin Inhibitors
  • Others

Idiopathic Pulmonary Fibrosis Treatment Market Breakup by Marketed drugs

  • Ofev
  • Esbriet
  • Pirfenidone
  • Actimmune
  • Nintedanib
  • Interferon Gamma-1b
  • Others

Idiopathic Pulmonary Fibrosis Market Breakup by Route of administration

  • Oral
1. Tablets
2. Capsules
  • Parentals
1. Intravenous
2. Intramuscular

Idiopathic Pulmonary Fibrosis Market Breakup by Drug type

  • Over the Counter
  • Prescription
1. Branded
2. Generics

Idiopathic Pulmonary Fibrosis Market Breakup by Treatment Channel

  • Public
  • Private

Idiopathic Pulmonary Fibrosis Market Breakup by End user

  • Hospitals
  • Specialty Clinics
  • Homecare Settings
  • Others

Idiopathic Pulmonary Fibrosis Market Breakup by Distribution Channel

  • Hospital Pharmacy
  • Retail Pharmacy
  • Online Pharmacy
  • Others

Idiopathic Pulmonary Fibrosis Treatment Market Breakup by Region

North America

  • United States of America
  • Canada

Europe

  • United Kingdom
  • Germany
  • France
  • Italy
  • Others

Asia Pacific

  • China
  • Japan
  • India
  • ASEAN
  • Australia
  • Others

Latin America

  • Brazil
  • Argentina
  • Mexico
  • Others

Middle East and Africa

  • Saudi Arabia
  • United Arab Emirates
  • Nigeria
  • South Africa
  • Others

Idiopathic Pulmonary Fibrosis Treatment Market Scenario

  • The global idiopathic pulmonary fibrosis (IPF) treatment market has seen steady growth due to increasing disease prevalence, improved diagnostic techniques, and the development of novel therapeutics. However, the market is also marked by significant unmet needs due to the progressive nature of the disease and the limited effectiveness of currently available treatments
  • Over the past decade, the introduction of antifibrotic drugs like pirfenidone and nintedanib, which can slow the disease's progression, has reshaped the IPF treatment landscape. These drugs have become the standard of care for many IPF patients and have driven market growth. The market is also buoyed by supportive therapies like oxygen therapy and pulmonary rehabilitation, which can help manage symptoms and improve quality of life for IPF patients
  • Increased awareness and improved diagnostic techniques have also contributed to market growth. High-resolution computed tomography (HRCT) and certain biomarkers have improved the ability to diagnose IPF earlier and more accurately, leading to an increase in the diagnosed prevalence of the disease
  • Despite these advances, the IPF treatment market is characterized by significant unmet needs. As of my knowledge cut-off in September 2021, there is no cure for IPF, and available treatments can only slow, not stop, the disease's progression. In addition, the side effects associated with current treatments can limit their use in some patients. There is also a need for more personalized treatment strategies, as the disease's course can vary significantly among patients
  • Looking forward, the IPF treatment market is expected to be driven by the development of novel therapeutics. Several potential treatments are in the pipeline, many of which aim to target different aspects of the disease's pathophysiology. If successful, these new therapies could significantly change the treatment paradigm for IPF
  • Regionally, the market is dominated by North America and Europe due to higher disease awareness, advanced healthcare systems, and the presence of key pharmaceutical companies. However, the Asia-Pacific region is expected to see rapid growth due to increasing disease prevalence and improving healthcare infrastructure
In conclusion, the global IPF treatment market is poised for growth, driven by increasing disease prevalence, improved diagnostics, and the development of novel therapeutics. However, the market is also characterized by significant unmet needs, highlighting the importance of ongoing research into new treatment strategies.

Key Players in the Global Idiopathic Pulmonary Fibrosis Treatment Market

The report gives an in-depth analysis of the key players involved in the Idiopathic Pulmonary Fibrosis Treatment market, sponsors manufacturing the drugs, and putting them through trials to get FDA approvals. The companies included in the market are as follows:
  • Boehringer Ingelheim International GmbH
  • AstraZeneca
  • F. Hoffmann-La Roche Ltd
  • Trevi Therapeutics
  • FibroGen,Inc
  • TORAY INDUSTRIES, INC
  • Pfizer Inc
  • Johnson & Johnson Services, Inc
  • Asahi Kasei Corporation
  • Galapagos NV
  • ZAMBON COMPANY S.P.A
  • Novartis AG
  • Neopharm Group
  • Galecto Biotech
  • Kadmon Holding, Inc
  • Promedior, Inc
  • Merck & Co.,Inc
  • Sanofi
  • Bristol-Myers Squibb Company
  • GlaxoSmithKline plc.

Table of Contents

1 Preface
1.1 Objectives of the Study
1.2 Key Assumptions
1.3 Report Coverage - Key Segmentation and Scope
1.4 Research Methodology
2 Executive Summary
3 Idiopathic Pulmonary Fibrosis Disease Overview
3.1 Guidelines and Stages
3.2 Pathophysiology
3.3 Screening and Diagnosis
3.4 Treatment Pathway
4 Patient Profile
4.1 Patient Profile Overview
4.2 Patient Psychology and Emotional Impact Factors
4.3 Risk Assessment and Treatment Success Rate
5 Idiopathic Pulmonary Fibrosis Epidemiology Analysis
5.1 Epidemiology Overview (2016-2031)
5.2 North America Idiopathic Pulmonary Fibrosis Epidemiology (2016-2031)
5.3 Europe Idiopathic Pulmonary Fibrosis Epidemiology (2016-2031)
5.4 Asia-Pacific Idiopathic Pulmonary Fibrosis Epidemiology (2016-2031)
5.5 Latin America Idiopathic Pulmonary Fibrosis Epidemiology (2016-2031)
5.6 Middle East & Africa Idiopathic Pulmonary Fibrosis Epidemiology (2016-2031)
6 Global Idiopathic Pulmonary Fibrosis Treatment Market Overview
6.1 Global Idiopathic Pulmonary Fibrosis Treatment Market Historical Value (2016-2022)
6.2 Global Idiopathic Pulmonary Fibrosis Treatment Market Forecast Value (2023-2031)
7 Global Idiopathic Pulmonary Fibrosis Treatment Market Landscape
7.1 Idiopathic Pulmonary Fibrosis Treatment: Developers Landscape
7.1.1 Analysis by Year of Establishment
7.1.2 Analysis by Company Size
7.1.3 Analysis by Region
7.2 Idiopathic Pulmonary Fibrosis Treatment: Product Landscape
7.2.1 Analysis by Drug Class
7.2.2 Analysis by Marketed Drugs
7.2.3 Analysis by Route of Administration
7.2.4 Analysis by Drug Type
7.2.5 Analysis by End User
8 Idiopathic Pulmonary Fibrosis Treatment Challenges and Unmet Needs
8.1 Treatment Pathway Challenges
8.2 Compliance and Drop-Out Analysis
8.3 Awareness and Prevention Gaps
9 Cost of Treatment
10 Global Idiopathic Pulmonary Fibrosis Treatment Market Dynamics
10.1 Market Drivers and Constraints
10.2 SWOT Analysis
10.3 Porter’s Five Forces Model
10.4 Key Demand Indicators
10.5 Key Price Indicators
10.6 Industry Events, Initiatives, and Trends
10.7 Value Chain Analysis
11 Global Idiopathic Pulmonary Fibrosis Treatment Market Segmentation
11.1 Global Idiopathic Pulmonary Fibrosis Treatment Market by Drug Class
11.1.1 Market Overview
11.1.2 Tyrosine Inhibitors
11.1.3 MAPK Inhibitors
11.1.4 Autotaxin Inhibitors
11.1.5 Others
11.2 Global Idiopathic Pulmonary Fibrosis Treatment Market by Marketed Drugs
11.2.1 Market Overview
11.2.2 Ofev
11.2.3 Esbriet
11.2.4 Pirfenidone
11.2.5 Actimmune
11.2.6 Nintedanib
11.2.7 Interferon Gamma-1b
11.2.8 Others
11.3 Global Idiopathic Pulmonary Fibrosis Treatment Market by Route of Administration
11.3.1 Market Overview
11.3.2 Oral
11.3.2.1 Tablets
11.3.2.2 Capsules
11.3.3 Parentals
11.3.3.1 Intravenous
11.3.3.2 Intramuscular
11.3.4 Others
11.4 Global Idiopathic Pulmonary Fibrosis Treatment Market by Drug Type
11.4.1 Market Overview
11.4.2 Over the Counter
11.4.3 Prescription
11.4.3.1 Branded
11.4.3.2 Generics
11.5 Global Idiopathic Pulmonary Fibrosis Treatment Market by Treatment Channel
11.5.1 Market Overview
11.5.2 Public
11.5.3 Private
11.6 Global Idiopathic Pulmonary Fibrosis Treatment Market by End User
11.6.1 Market Overview
11.6.2 Hospitals
11.6.3 Specialty Clinics
11.6.4 Homecare Settings
11.6.5 Others
11.7 Global Idiopathic Pulmonary Fibrosis Treatment Market by Distribution Channel
11.7.1 Market Overview
11.7.2 Hospital Pharmacy
11.7.3 Retail Pharmacy
11.7.4 Online Pharmacy
11.7.5 Others
11.8 Global Idiopathic Pulmonary Fibrosis Treatment Market by Region
11.8.1 Market Overview
11.8.2 North America
11.8.3 Europe
11.8.4 Asia Pacific
11.8.5 Latin America
11.8.6 Middle East and Africa
12 North America Idiopathic Pulmonary Fibrosis Treatment Market
12.1 Market Share by Country
12.2 United States of America
12.3 Canada
13 Europe Idiopathic Pulmonary Fibrosis Treatment Market
13.1 Market Share by Country
13.2 United Kingdom
13.3 Germany
13.4 France
13.5 Italy
13.6 Others
14 Asia Pacific Idiopathic Pulmonary Fibrosis Treatment Market
14.1 Market Share by Country
14.2 China
14.3 Japan
14.4 India
14.5 ASEAN
14.6 Australia
14.7 Others
15 Latin America Idiopathic Pulmonary Fibrosis Treatment Market
15.1 Market Share by Country
15.2 Brazil
15.3 Argentina
15.4 Mexico
15.5 Others
16 Middle East and Africa Idiopathic Pulmonary Fibrosis Treatment Market
16.1 Market Share by Country
16.2 Saudi Arabia
16.3 United Arab Emirates
16.4 Nigeria
16.5 South Africa
16.6 Others
17 Regulatory Framework
17.1 Regulatory Overview
17.1.1 US FDA
17.1.2 EU EMA
17.1.3 INDIA CDSCO
17.1.4 JAPAN PMDA
17.1.5 Others
18 Patent Analysis
18.1 Analysis by Type of Patent
18.2 Analysis by Publication year
18.3 Analysis by Issuing Authority
18.4 Analysis by Patent Age
18.5 Analysis by CPC Analysis
18.6 Analysis by Patent Valuation
18.7 Analysis by Key Players
19 Grants Analysis
19.1 Analysis by year
19.2 Analysis by Amount Awarded
19.3 Analysis by Issuing Authority
19.4 Analysis by Grant Application
19.5 Analysis by Funding Institute
19.6 Analysis by NIH Departments
19.7 Analysis by Recipient Organization
20 Clinical Trials Analysis
20.1 Analysis by Trial Registration Year
20.2 Analysis by Trial Status
20.3 Analysis by Trial Phase
20.4 Analysis by Therapeutic Area
20.5 Analysis by Geography
21 Funding and Investment Analysis
21.1 Analysis by Funding Instances
21.2 Analysis by Type of Funding
21.3 Analysis by Funding Amount
21.4 Analysis by Leading Players
21.5 Analysis by Leading Investors
21.6 Analysis by Geography
22 Partnership and Collaborations Analysis
22.1 Analysis by Partnership Instances
22.2 Analysis by Type of Partnership
22.3 Analysis by Leading Players
22.4 Analysis by Geography
23 Supplier Landscape
23.1 Boehringer Ingelheim International GmbH.
23.1.1 Financial Analysis
23.1.2 Product Portfolio
23.1.3 Demographic Reach and Achievements
23.1.4 Mergers and Acquisitions
23.1.5 Certifications
23.2 AstraZeneca
23.2.1 Financial Analysis
23.2.2 Product Portfolio
23.2.3 Demographic Reach and Achievements
23.2.4 Mergers and Acquisitions
23.2.5 Certifications
23.3 F. Hoffmann-La Roche Ltd.
23.3.1 Financial Analysis
23.3.2 Product Portfolio
23.3.3 Demographic Reach and Achievements
23.3.4 Mergers and Acquisitions
23.3.5 Certifications
23.4 Trevi Therapeutics
23.4.1 Financial Analysis
23.4.2 Product Portfolio
23.4.3 Demographic Reach and Achievements
23.4.4 Mergers and Acquisitions
23.4.5 Certifications
23.5 FibroGen,Inc.
23.5.1 Financial Analysis
23.5.2 Product Portfolio
23.5.3 Demographic Reach and Achievements
23.5.4 Mergers and Acquisitions
23.5.5 Certifications
23.6 TORAY INDUSTRIES, INC.
23.6.1 Financial Analysis
23.6.2 Product Portfolio
23.6.3 Demographic Reach and Achievements
23.6.4 Mergers and Acquisitions
23.6.5 Certifications
23.7 Pfizer Inc.
23.7.1 Financial Analysis
23.7.2 Product Portfolio
23.7.3 Demographic Reach and Achievements
23.7.4 Mergers and Acquisitions
23.7.5 Certifications
23.8 Johnson & Johnson Services, Inc.
23.8.1 Financial Analysis
23.8.2 Product Portfolio
23.8.3 Demographic Reach and Achievements
23.8.4 Mergers and Acquisitions
23.8.5 Certifications
23.9 Asahi Kasei Corporation
23.9.1 Financial Analysis
23.9.2 Product Portfolio
23.9.3 Demographic Reach and Achievements
23.9.4 Mergers and Acquisitions
23.9.5 Certifications
23.10 Galapagos NV
23.10.1 Financial Analysis
23.10.2 Product Portfolio
23.10.3 Demographic Reach and Achievements
23.10.4 Mergers and Acquisitions
23.10.5 Certifications
23.11 ZAMBON COMPANY S.P.A.
23.11.1 Financial Analysis
23.11.2 Product Portfolio
23.11.3 Demographic Reach and Achievements
23.11.4 Mergers and Acquisitions
23.11.5 Certifications
23.12 Novartis AG
23.12.1 Financial Analysis
23.12.2 Product Portfolio
23.12.3 Demographic Reach and Achievements
23.12.4 Mergers and Acquisitions
23.12.5 Certifications
23.13 Neopharm Group
23.13.1 Financial Analysis
23.13.2 Product Portfolio
23.13.3 Demographic Reach and Achievements
23.13.4 Mergers and Acquisitions
23.13.5 Certifications
23.14 Galecto Biotech
23.14.1 Financial Analysis
23.14.2 Product Portfolio
23.14.3 Demographic Reach and Achievements
23.14.4 Mergers and Acquisitions
23.14.5 Certifications
23.15 Kadmon Holding, Inc.
23.15.1 Financial Analysis
23.15.2 Product Portfolio
23.15.3 Demographic Reach and Achievements
23.15.4 Mergers and Acquisitions
23.15.5 Certifications
23.16 Promedior, Inc.
23.16.1 Financial Analysis
23.16.2 Product Portfolio
23.16.3 Demographic Reach and Achievements
23.16.4 Mergers and Acquisitions
23.16.5 Certifications
23.17 Merck & Co.,Inc.
23.17.1 Financial Analysis
23.17.2 Product Portfolio
23.17.3 Demographic Reach and Achievements
23.17.4 Mergers and Acquisitions
23.17.5 Certifications
23.18 Sanofi
23.18.1 Financial Analysis
23.18.2 Product Portfolio
23.18.3 Demographic Reach and Achievements
23.18.4 Mergers and Acquisitions
23.18.5 Certifications
23.19 Bristol-Myers Squibb Company
23.19.1 Financial Analysis
23.19.2 Product Portfolio
23.19.3 Demographic Reach and Achievements
23.19.4 Mergers and Acquisitions
23.19.5 Certifications
23.20 GlaxoSmithKline plc.
23.20.1 Financial Analysis
23.20.2 Product Portfolio
23.20.3 Demographic Reach and Achievements
23.20.4 Mergers and Acquisitions
23.20.5 Certifications
24 Idiopathic Pulmonary Fibrosis Treatment Market- Distribution Model (Additional Insight)
24.1 Overview
24.2 Potential Distributors
24.3 Key Parameters for Distribution Partner Assessment
25 Key Opinion Leaders (KOL) Insights (Additional Insight)
26 Company Competitiveness Analysis (Additional Insight)
26.1 Very Small Companies
26.2 Small Companies
26.3 Mid-Sized Companies
26.4 Large Companies
26.5 Very Large Companies
27 Payment Methods (Additional Insight)
27.1 Government Funded
27.2 Private Insurance
27.3 Out-of-Pocket

Companies Mentioned

  • Boehringer Ingelheim International Gmbh.
  • Astrazeneca
  • F. Hoffmann-La Roche Ltd.
  • Trevi Therapeutics
  • Fibrogen,Inc.
  • Toray Industries, Inc.
  • Pfizer Inc.
  • Johnson & Johnson Services, Inc.
  • Asahi Kasei Corporation
  • Galapagos Nv
  • Zambon Company S.P.A.
  • Novartis AG
  • Neopharm Group
  • Galecto Biotech
  • Kadmon Holding, Inc.
  • Promedior, Inc.
  • Merck & Co.Inc.
  • Sanofi
  • Bristol-Myers Squibb Company
  • GlaxoSmithKline plc.

Methodology

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