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Topical Pain Relief Market Size and Share Outlook - Forecast Trends and Growth Analysis Report (2025-2034)

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    Report

  • 400 Pages
  • June 2025
  • Region: Global
  • Expert Market Research
  • ID: 5805825
The global topical pain relief market attained a value of D 10.61 Billion in 2024, driven by the rising prevalence of arthritis and bone-related diseases, and the growing geriatric population across the globe. The market is further expected to grow at a CAGR of 5.00% during the forecast period of 2025-2034 to reach nearly USD 17.28 Billion by 2034.

Topical Pain Relief Market Overview

Topical pain relief agents are used to treat muscle pains, sprains, and strains. They can also help relieve painful arthritis. Since topical analgesics have fewer side effects than oral painkillers, they are often prescribed instead of oral painkillers. Factors driving market growth include increased adoption of topical pain-relieving drugs, which have fewer side effects than oral pain relievers, the growing global geriatric population, and an increase in demand for topical pain relievers among athletes. Further, expanding online retail channels for topical therapeutics is expected to provide the industry with lucrative growth opportunities.

Topical Pain Relief Market Growth Drivers

Rising Incidence of Bone-related Issues Boost the Market Growth

The World Health Organization estimated that around 619 million individuals registered with lower back pain (LBP) in 2020. These cases are expected to increase to 843 million cases by 2050. The growing geriatric population significantly drives the increase in the number of cases.

The increasing prevalence of arthritis and other bone-related diseases, as well as diabetic neuropathy, which causes pain, is driving the growth of the market.

Expedited Product Developments to Meet Rising Topical Pain Relief Market Demand

The market is significantly driven by the rising demand for non-invasive, fast-acting pain relief solutions. The market players are considering consumer preference for different formulations and forms of topical analgesics. For instance, in September 2024, Mankind Pharma’s consumer business division launched a new solution for neck pain, Nimulid Strong, a gel and spray formulation to address neck pain, which impacts overall body function. The new solution has 2x diclofenac concentration that claims fast pain relief. This focus on consumer preference is poised to augment the increased adoption of newly launched topical solutions, especially in spray forms, bolstering market growth.

Further, the growing demand for non-opioid pain relief solutions, coupled with increasing consumer preference for over-the-counter (OTC) medications is driving innovation in the topical pain management market. Moreover, the rising awareness of the harmful side effects of consuming oral pain relievers for the long term is further creating a need for market players to develop targeted, user-friendly solutions. For instance, in September 2023, Kenvue Inc. showcased its new topical Tylenol Precise Pain Relieving Cream at PAINWeek Conference 2023. The new pain reliever ointment consists of maximum-strength lidocaine 40% that provides targeted pain relief seamlessly. In view of recent consumer data, around 40% of individuals dislike the way medicated topical solutions smell and feel. Therefore, Kenvue designed a hands-free application with a rollerball with a fresh scent and fragrance-free formula to enhance the consumer experience.

Topical Pain Relief Market Trends

The market is witnessing several trends and developments to improve the current scenario. Some of the notable trends are as follows:

Increasing Demand for Natural and Organic Ingredients

The market is witnessing increasing demand for naturally curated natural ingredients due to the rising awareness about synthetic chemicals and potential side effects.

Rising Availability of OTC Solutions

The market is witnessing a growing preference for topical analgesics due to their safety profile against oral pain medications, accelerating their adoption. There is a growing preference for OTC topical pain relief solutions, as consumers are looking for easily available products such as ointments, and drugs, among other pain relief solutions.

Improved Formulations for Enhanced Patient Experience to Boost Topical Pain Relief Market Value

Due to the inconvenience caused by the greasy and oily topical solutions, consumers are increasingly preferring improved solutions that are non-greasy and fast absorbing, contributing to enhanced patient experience.

Adoption of CBD-Based Topical Solutions

The market is experiencing a trend where the use of cannabidiol (CBD) in topical pain relief has increased as it has anti-inflammatory and analgesic properties. Some popular products include CBD-infused creams, gels and balms.

Topical Pain Relief Market Segmentation

"Topical Pain Relief Market Report and Forecast 2025-2034” offers a detailed analysis of the market based on the following segments:

Market Breakup by Therapeutics

  • Non-Opioids
  • Nonsteroidal anti-inflammatory drug (NSAIDs)
  • Methyl Salicylates
  • Lidocaine
  • Capsaicin
  • Others
  • Opioids
  • Buprenorphine
  • Fentanyl

Market Breakup by Formulation

  • Cream
  • Spray
  • Gel
  • Patch
  • Others

Market Breakup by Distribution Channel

  • Pharmacies and Drug Stores
  • Retail and Grocery Stores
  • E-commerce

Market Breakup by Region

  • United States
  • EU-4 and the United Kingdom
  • Germany
  • France
  • Italy
  • Spain
  • United Kingdom
  • Japan
  • India

Topical Pain Relief Market Share

Cream Formulation Leads the Market Share

The market segmentation by formulation includes cream, spray, gel, patch, and others. Cream formulations are expected to lead the market share due to their widespread use, ease of application, and effectiveness in delivering pain relief. Consumers prefer creams as they get easily absorbed into the skin, offering fast-acting relief for localised pain such as muscle aches, joint pain, and arthritis. Additionally, creams often contain popular active ingredients like menthol, capsaicin, or lidocaine, which are highly effective in targeting pain receptors. Their non-greasy texture and availability in over-the-counter and prescription forms contribute to the high demand and increased adoption in the market.

Topical Pain Relief Market Analysis by Region

Based on region, the United States leads the regional market share, driven by the rising prevalence of chronic pain conditions such as arthritis, back pain, and neuropathy. The market is further driven by the growing geriatric population, and a shift towards self-medication for pain management, contributing to increased adoption of topical pain relief solutions. Increasing awareness about non-opioid alternatives for pain management is collectively fueling the demand for topical pain relief products in the market. Technological advancements in product formulations, including innovations like lidocaine patches and menthol-based creams are attracting a large consumer base, thereby increasing the market share of the region. Moreover, consumer preference for over-the-counter (OTC) products and the widespread availability of topical solutions across various retail channels, including e-commerce, are accelerating the market expansion in the United States.

Leading Players in the Topical Pain Relief Market

The key features of the market report comprise patent analysis, clinical trials analysis, grant analysis, funding and investment analysis and strategic initiatives by the leading players. The major companies in the market are as follows:

Johnson & Johnson

Headquartered in New Jersey, USA, Johnson & Johnson is a multinational pharmaceutical, biotechnology, and medical technologies conglomerate specialising in surgical instruments and technologies.

Pfizer Inc

Founded in 1849 and headquartered in New York City, Pfizer is a leading biopharmaceutical company. It is renowned for its extensive portfolio in the pharmaceutical market, offering treatments for various medical fields, including oncology, vaccines, internal medicine, and rare diseases, with a strong focus on innovative research.

GSK plc

Founded in 2000 and headquartered in London, GSK plc is a global pharmaceutical company specialising in the research and development of vaccines, medicines, and consumer healthcare products. GSK offers products like Voltaren and Panadol, providing effective solutions for pain management through topical gels and creams.

Sanofi S.A.

Sanofi is a multinational pharmaceutical company with a focus on research and development across various therapeutic areas. Sanofi’s portfolio includes antiretroviral therapies and immunotherapies aimed at improving viral suppression and enhancing patient quality of life.

Reckitt Benckiser Group plc

Reckitt Benckiser Group plc, established in 1999 and headquartered in Slough, England, is a global consumer goods company. Its portfolio in topical pain relief includes well-known brands like Nurofen and Deep Heat, offering a range of products such as gels, creams, and patches for effective pain management.

Other key players in the market include Topical Biomedics, Hisamitsu Pharmaceutical Co., Inc., Sun Pharmaceutical Industries Ltd, and Haw Par Corporation Ltd

Key Questions Answered in the Topical Pain Relief Market

  • What was the topical pain relief market value in 2024?
  • What is the topical pain relief market forecast outlook for 2025-2034?
  • What is market segmentation based on therapeutics?
  • How does segmentation by formulation influence market dynamics?
  • What are the distribution channels in the market?
  • What are the major factors aiding the topical pain relief market demand?
  • How has the market performed so far and how is it anticipated to perform in the coming years?
  • What are the market's major drivers, opportunities, and restraints?
  • Which country is expected to experience expedited growth during the forecast period?
  • What are the major topical pain relief market trends?
  • Which therapeutic is expected to dominate the market?
  • Which formulation will lead the market segment?
  • Which distribution channel will lead the market?
  • Who are the key players involved in the topical pain relief market?
  • What is the patent landscape of the market?
  • What are the current unmet needs and challenges in the market?
  • How are partnerships, collaborations, mergers, and acquisitions among the key market players shaping the market dynamics?

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Table of Contents

1 Preface
1.1 Objectives of the Study
1.2 Key Assumptions
1.3 Report Coverage - Key Segmentation and Scope
1.4 Research Methodology
2 Executive Summary
3 Topical Pain Relief Market Overview: 8 Major Markets
3.1 Topical Pain Relief Market Historical Value (2018-2024)
3.2 Topical Pain Relief Market Forecast Value (2025-2034)
4 Vendor Positioning Analysis
4.1 Key Vendors
4.2 Prospective Leaders
4.3 Niche Leaders
4.4 Disruptors
5 Topical Pain Relief: Disease Overview
5.1 Guidelines and Stages
5.2 Pathophysiology
5.3 Screening and Diagnosis
5.4 Therapy Pathway
6 Patient Profile
6.1 Patient Profile Overview
6.2 Patient Psychology and Emotional Impact Factors
6.3 Risk Assessment and Therapy Success Rate
7 Topical Pain Relief Market Epidemiology Scenario and Forecast - 8 Major Markets
7.1 8MM Epidemiology Scenario Overview (2018-2034)
7.1.1 Prevalence, by Country
7.1.1.1 United States
7.1.1.2 United Kingdom
7.1.1.3 EU4
7.1.1.4 India
7.1.1.5 Japan
7.1.2 Diagnosed Cases, by Country
7.1.2.1 United States
7.1.2.2 United Kingdom
7.1.2.3 EU4
7.1.2.4 India
7.1.2.5 Japan
7.1.3 Treatment Seeking Rate, by Country
7.1.3.1 United States
7.1.3.2 United Kingdom
7.1.3.3 EU4
7.1.3.4 India
7.1.3.5 Japan
8 Topical Pain Relief Market Landscape: 8 Major Markets*
8.1 Topical Pain Relief Market: Developers Landscape
8.1.1 Analysis by Year of Establishment
8.1.2 Analysis by Company Size
8.1.3 Analysis by Region
8.2 Topical Pain Relief Market: Product Landscape
8.2.1 Analysis by Type
8.2.2 Analysis by Route of Administration
9 Topical Pain Relief Market Challenges and Unmet Needs
9.1 Therapy Pathway Challenges
9.2 Compliance and Drop-Out Analysis
9.3 Awareness and Prevention Gaps
10 Cost of Treatment
11 Topical Pain Relief Market Dynamics
11.1 Market Drivers and Constraints
11.2 SWOT Analysis
11.2.1 Strengths
11.2.2 Weaknesses
11.2.3 Opportunities
11.2.4 Threats
11.3 PESTEL Analysis
11.3.1 Political
11.3.2 Economic
11.3.3 Social
11.3.4 Technological
11.3.5 Legal
11.3.6 Environment
11.4 Porter’s Five Forces Model
11.4.1 Bargaining Power of Suppliers
11.4.2 Bargaining Power of Buyers
11.4.3 Threat of New Entrants
11.4.4 Threat of Substitutes
11.4.5 Degree of Rivalry
11.5 Key Demand Indicators
11.6 Key Price Indicators
11.7 Industry Events, Initiatives, and Trends
11.8 Value Chain Analysis
12 Topical Pain Relief Market Segmentation: 8 Major Markets
12.1 Topical Pain Relief Market (2018-2034) by Therapeutic
12.1.1 Market Overview
12.1.2 Non-Opioids
12.1.2.1 Nonsteroidal anti-inflammatory drug (NSAIDs)
12.1.2.2 Methyl Salicylates
12.1.2.3 Lidocaine
12.1.2.4 Capsaicin
12.1.2.5 Others
12.1.3 Opioids
12.1.3.1 Buprenorphine
12.1.3.2 Fentanyl
12.2 Topical Pain Relief Market (2018-2034) by Formulation
12.2.1 Market Overview
12.2.2 Cream
12.2.3 Spray
12.2.4 Gel
12.2.5 Patch
12.2.6 Others
12.3 Topical Pain Relief Market (2018-2034) by Distribution Channel
12.3.1 Market Overview
12.3.2 Pharmacies and Drug Stores
12.3.3 Retail and Grocery Stores
12.3.4 E-commerce
12.4 Topical Pain Relief Market (2018-2034) by Region
12.4.1 Market Overview
12.4.2 United States
12.4.3 EU-4 and the United Kingdom
12.4.3.1 Germany
12.4.3.2 France
12.4.3.3 Italy
12.4.3.4 Spain
12.4.3.5 United Kingdom
12.4.4 Japan
12.4.5 India
13 United States Topical Pain Relief Market (218-2034)
13.1 United States Topical Pain Relief Market Historical Value (2018-2024)
13.2 United States Topical Pain Relief Market Forecast Value (2025-2034)
13.3 United States Topical Pain Relief Market (2018-2034) by Therapeutic
13.3.1 Market Overview
13.3.2 Non-Opioids
13.3.2.1 Nonsteroidal anti-inflammatory drug (NSAIDs)
13.3.2.2 Methyl Salicylates
13.3.2.3 Lidocaine
13.3.2.4 Capsaicin
13.3.2.5 Others
13.3.3 Opioids
13.3.3.1 Buprenorphine
13.3.3.2 Fentanyl
13.4 United States Topical Pain Relief Market (2018-2034) by Formulation
13.4.1 Market Overview
13.4.2 Cream
13.4.3 Spray
13.4.4 Gel
13.4.5 Patch
13.4.6 Others
13.5 United States Topical Pain Relief Market (2018-2034) by Distribution Channel
13.5.1 Market Overview
13.5.2 Pharmacies and Drug Stores
13.5.3 Retail and Grocery Stores
13.5.4 E-commerce
14 EU-4 and United Kingdom Topical Pain Relief Market (218-2034)
14.1 EU-4 and United Kingdom Topical Pain Relief Market Historical Value (2018-2024)
14.2 EU-4 and United Kingdom Topical Pain Relief Market Forecast Value (2025-2034)
14.3 EU-4 and United Kingdom Topical Pain Relief Market (2018-2034) by Therapeutic
14.3.1 Market Overview
14.3.2 Non-Opioids
14.3.2.1 Nonsteroidal anti-inflammatory drug (NSAIDs)
14.3.2.2 Methyl Salicylates
14.3.2.3 Lidocaine
14.3.2.4 Capsaicin
14.3.2.5 Others
14.3.3 Opioids
14.3.3.1 Buprenorphine
14.3.3.2 Fentanyl
14.4 EU-4 and United Kingdom Topical Pain Relief Market (2018-2034) by Formulation
14.4.1 Market Overview
14.4.2 Cream
14.4.3 Spray
14.4.4 Gel
14.4.5 Patch
14.4.6 Others
14.5 EU-4 and United Kingdom Topical Pain Relief Market (2018-2034) by Distribution Channel
14.5.1 Market Overview
14.5.2 Pharmacies and Drug Stores
14.5.3 Retail and Grocery Stores
14.5.4 E-commerce
15 Japan Topical Pain Relief Market (218-2034)
15.1 Japan Topical Pain Relief Market Historical Value (2018-2024)
15.2 Japan Topical Pain Relief Market Forecast Value (2025-2034)
15.3 Japan Topical Pain Relief Market (2018-2034) by Therapeutic
15.3.1 Market Overview
15.3.2 Non-Opioids
15.3.2.1 Nonsteroidal anti-inflammatory drug (NSAIDs)
15.3.2.2 Methyl Salicylates
15.3.2.3 Lidocaine
15.3.2.4 Capsaicin
15.3.2.5 Others
15.3.3 Opioids
15.3.3.1 Buprenorphine
15.3.3.2 Fentanyl
15.4 Japan Topical Pain Relief Market (2018-2034) by Formulation
15.4.1 Market Overview
15.4.2 Cream
15.4.3 Spray
15.4.4 Gel
15.4.5 Patch
15.4.6 Others
15.5 Japan Topical Pain Relief Market (2018-2034) by Distribution Channel
15.5.1 Market Overview
15.5.2 Pharmacies and Drug Stores
15.5.3 Retail and Grocery Stores
15.5.4 E-commerce
16 India Topical Pain Relief Market (218-2034)
16.1 India Topical Pain Relief Market Historical Value (2018-2024)
16.2 India Topical Pain Relief Market Forecast Value (2025-2034)
16.3 India Topical Pain Relief Market (2018-2034) by Therapeutic
16.3.1 Market Overview
16.3.2 Non-Opioids
16.3.2.1 Nonsteroidal anti-inflammatory drug (NSAIDs)
16.3.2.2 Methyl Salicylates
16.3.2.3 Lidocaine
16.3.2.4 Capsaicin
16.3.2.5 Others
16.3.3 Opioids
16.3.3.1 Buprenorphine
16.3.3.2 Fentanyl
16.4 India Topical Pain Relief Market (2018-2034) by Formulation
16.4.1 Market Overview
16.4.2 Cream
16.4.3 Spray
16.4.4 Gel
16.4.5 Patch
16.4.6 Others
16.5 India Topical Pain Relief Market (2018-2034) by Distribution Channel
16.5.1 Market Overview
16.5.2 Pharmacies and Drug Stores
16.5.3 Retail and Grocery Stores
16.5.4 E-commerce
17 Regulatory Framework
17.1 Regulatory Overview
17.2 US FDA
17.3 EU EMA
17.4 INDIA CDSCO
17.5 JAPAN PMDA
17.6 Others
18 Patent Analysis
18.1 Analysis by Type of Patent
18.2 Analysis by Publication Year
18.3 Analysis by Issuing Authority
18.4 Analysis by Patent Age
18.5 Analysis by CPC Analysis
18.6 Analysis by Patent Valuation
18.7 Analysis by Key Players
19 Clinical Trial Analysis
19.1 Analysis by Trial Registration Year
19.2 Analysis by Trial Status
19.3 Analysis by Trial Phase
19.4 Analysis by Therapeutic Area
19.5 Analysis by Geography
20 Grant Analysis
20.1 Analysis by Year
20.2 Analysis by Amount Awarded
20.3 Analysis by Issuing Authority
20.4 Analysis by Grant Product
20.5 Analysis by Funding Institute
20.6 Analysis by Departments
20.7 Analysis by Recipient Organization
21 Funding and Investment Analysis
21.1 Analysis by Funding Instances
21.2 Analysis by Drug Type of Funding
21.3 Analysis by Funding Amount
21.4 Analysis by Leading Players
21.5 Analysis by Leading Investors
21.6 Analysis by Geography
22 Strategic Initiatives
22.1 Analysis by Partnership Instances
22.2 Analysis by Type of Partnership
22.3 Analysis by Leading Players
22.4 Analysis by Geography
23 Supplier Landscape
23.1 Market Share by Top 5 Companies
23.2 Johnson & Johnson
23.2.1 Financial Analysis
23.2.2 Product Portfolio
23.2.3 Demographic Reach and Achievements
23.2.4 Company News and Developments
23.2.5 Certifications
23.3 Pfizer Inc.
23.3.1 Financial Analysis
23.3.2 Product Portfolio
23.3.3 Demographic Reach and Achievements
23.3.4 Company News and Developments
23.3.5 Certifications
23.4 Novartis AG
23.4.1 Financial Analysis
23.4.2 Product Portfolio
23.4.3 Demographic Reach and Achievements
23.4.4 Company News and Developments
23.4.5 Certifications
23.5 GSK plc
23.5.1 Financial Analysis
23.5.2 Product Portfolio
23.5.3 Demographic Reach and Achievements
23.5.4 Company News and Developments
23.5.5 Certifications
23.6 Sanofi S.A.
23.6.1 Financial Analysis
23.6.2 Product Portfolio
23.6.3 Demographic Reach and Achievements
23.6.4 Company News and Developments
23.6.5 Certifications
23.7 Reckitt Benckiser Group plc
23.7.1 Financial Analysis
23.7.2 Product Portfolio
23.7.3 Demographic Reach and Achievements
23.7.4 Company News and Developments
23.7.5 Certifications
23.8 Topical Biomedics, Inc.
23.8.1 Financial Analysis
23.8.2 Product Portfolio
23.8.3 Demographic Reach and Achievements
23.8.4 Company News and Developments
23.8.5 Certifications
23.9 Hisamitsu Pharmaceutical Co., Inc.
23.9.1 Financial Analysis
23.9.2 Product Portfolio
23.9.3 Demographic Reach and Achievements
23.9.4 Company News and Developments
23.9.5 Certifications
23.10 Sun Pharmaceutical Industries Ltd.
23.10.1 Financial Analysis
23.10.2 Product Portfolio
23.10.3 Demographic Reach and Achievements
23.10.4 Company News and Developments
23.10.5 Certifications
23.11 Haw Par Corporation Ltd.
23.11.1 Financial Analysis
23.11.2 Product Portfolio
23.11.3 Demographic Reach and Achievements
23.11.4 Company News and Developments
23.11.5 Certifications
24 Topical Pain Relief Market - Distribution Model (Additional Insight)
24.1 Overview
24.2 Potential Distributors
24.3 Key Parameters for Distribution Partner Assessment
25 Key Opinion Leaders (KOL) Insights (Additional Insight)
26 Payment Methods (Additional Insight)
26.1 Government Funded
26.2 Private Insurance
26.3 Out-of-Pocket

Companies Mentioned

  • Johnson & Johnson
  • Pfizer Inc.
  • GSK plc
  • Sanofi S.A.
  • Reckitt Benckiser Group plc

Table Information