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VX-121 Emerging Drug Insight and Market Forecast - 2032

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    Drug Pipelines

  • 30 Pages
  • July 2023
  • Region: Global
  • DelveInsight
  • ID: 5849480
“This “VX-121 Emerging Drug Insight and Market Forecast - 2032” report provides comprehensive insights about VX-121 for Cystic Fibrosis in the six major markets. A detailed picture of the VX-121 for cystic fibrosis in the 6MM, i.e., the United States, EU4 (Germany, France, Italy, and Spain) and the United Kingdom for the study period 2019 -2032 is provided in this report along with a detailed description of the VX-121 for cystic fibrosis. The report provides insights about mechanism of action, dosage and administration, as well as research and development including regulatory milestones, along with other developmental activities. Further, it also consists of future market assessments inclusive of the VX-121 market forecast analysis for cystic fibrosis in the 6MM, SWOT, analysts' views, comprehensive overview of market competitors, and brief about other emerging therapies in cystic fibrosis.

Drug Summary

VX-121 is an orally administered CFTR corrector that helps fix and restore the function of defective CFTR protein. The corrected CFTR protein can then translocate to the cell surface where it performs the normal function and helps maintain the right balance of fluid in the airways.

The company is investigating other potential small molecule medicines targeting the underlying cause of CF. In people with certain types of mutations in the CFTR gene, the CFTR protein is not processed and cannot move through the cell normally. This results in little to no protein at the cell surface.

VX-121 and tezacaftor are designed to increase the amount of mature protein at the cell surface by targeting the processing and trafficking defect of the CFTR protein. VX-561 (deutivacaftor) is a potentiator designed to keep CFTR proteins at the cell surface open longer to improve the flow of salt and water across the cell membrane, which helps hydrate and clear mucus from the airways. The triple combination of VX-121/tezacaftor/VX-561 is being developed as an investigational once-daily treatment for people with CF with certain mutations in the CFTR gene.

Scope of the Report

The report provides insights into:
  • A comprehensive product overview including the VX-121 description, mechanism of action, dosage and administration, research and development activities in cystic fibrosis.
  • Elaborated details on VX-121 regulatory milestones and other development activities have been provided in this report.
  • The report also highlights the VX-121 research and development activities in cystic fibrosis across the United States and Europe.
  • The report also covers the patents information with expiry timeline around VX-121.
  • The report contains forecasted sales of VX-121 for cystic fibrosis till 2032.
  • Comprehensive coverage of the late-stage emerging therapies for cystic fibrosis.
  • The report also features the SWOT analysis with analyst views for VX-121 in cystic fibrosis.

Methodology

The report is built using data and information sourced primarily from internal databases, primary and secondary research and in-house analysis by the publisher's team of industry experts. Information and data from the secondary sources have been obtained from various printable and nonprintable sources like search engines, news websites, global regulatory authorities websites, trade journals, white papers, magazines, books, trade associations, industry associations, industry portals and access to available databases.

VX-121 Analytical Perspective

In-depth VX-121 Market Assessment

This report provides a detailed market assessment of VX-121 for cystic fibrosis in the six major markets, i.e., the United States, EU4 (Germany, France, Italy, and Spain) and the United Kingdom. This segment of the report provides forecasted sales data from 2024 to 2032.

VX-121 Clinical Assessment

The report provides the clinical trials information of VX-121 for cystic fibrosis covering trial interventions, trial conditions, trial status, start and completion dates.

Report Highlights

  • In the coming years, the market scenario for cystic fibrosis is set to change due to the extensive research and incremental healthcare spending across the world; which would expand the size of the market to enable the drug manufacturers to penetrate more into the market.
  • The companies are developing therapies that focus on novel approaches to treat/improve the disease condition, assess challenges, and seek opportunities that could influence VX-121 dominance.
  • Other emerging products for cystic fibrosis are expected to give tough market competition to VX-121 and launch of late-stage emerging therapies in the near future will significantly impact the market.
  • A detailed description of regulatory milestones, and developmental activities, provide the current development scenario of VX-121 in cystic fibrosis.
  • The in-depth analysis of the forecasted sales data of VX-121 from 2024 to 2032 will support the clients in the decision-making process regarding their therapeutic portfolio by identifying the overall scenario of the VX-121 in cystic fibrosis.

Key Questions Answered

  • What is the product type, route of administration and mechanism of action of VX-121?
  • What is the clinical trial status of the study related to VX-121 in cystic fibrosis and study completion date?
  • What are the key collaborations, mergers and acquisitions, licensing and other activities related to the VX-121 development?
  • What are the key designations that have been granted to VX-121 for cystic fibrosis?
  • What is the forecasted market scenario of VX-121 for cystic fibrosis?
  • What are the forecasted sales of VX-121 in the six major countries, including the United States and Europe (Germany, France, Italy, Spain, and the United Kingdom)?
  • What are the other emerging products available and how are these giving competition to VX-121 for cystic fibrosis?
  • Which are the late-stage emerging therapies under development for the treatment of cystic fibrosis?


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Table of Contents

1. Report Introduction
2. VX-121 Overview in Cystic Fibrosis
2.1. Product Detail
2.2. Clinical Development
2.2.1. Clinical studies
2.2.2. Clinical trials information
2.2.3. Safety and efficacy
2.3. Other Developmental Activities
2.4. Product Profile
3. Competitive Landscape (Marketed Therapies)4. Competitive Landscape (Late-stage Emerging Therapies)
5. VX-121 Market Assessment
5.1. Market Outlook of VX-121 in Cystic Fibrosis
5.2. 6MM Analysis
5.2.1. Market Size of VX-121 in the 6MM for Cystic Fibrosis
5.3. Country-wise Market Analysis
5.3.1. Market Size of VX-121 in the United States for Cystic Fibrosis
5.3.2. Market Size of VX-121 in Germany for Cystic Fibrosis
5.3.3. Market Size of VX-121 in France for Cystic Fibrosis
5.3.4. Market Size of VX-121 in Italy for Cystic Fibrosis
5.3.5. Market Size of VX-121 in Spain for Cystic Fibrosis
5.3.6. Market Size of VX-121 in the United Kingdom for Cystic Fibrosis
6. SWOT Analysis7. Analysts’ Views
8. Appendix
8.1. Bibliography
8.2. Report Methodology
9. Publisher Capabilities10. Disclaimer11. About the Publisher12. Report Purchase Options
List of Tables
Table 1: VX-121, Clinical Trial Description, 2023
Table 2: VX-121, General Description
Table 3: Competitive Landscape (Marketed Therapies)
Table 4: Competitive Landscape (Emerging Therapies)
Table 5: VX-121 Market Size in the 6MM, in USD million (2019-2032)
Table 6: VX-121 Market Size in the US, in USD million (2019-2032)
Table 7: VX-121 Market Size in Germany, in USD million (2019-2032)
Table 8: VX-121 Market Size in France, in USD million (2019-2032)
Table 9: VX-121 Market Size in Italy, in USD million (2019-2032)
Table 10: VX-121 Market Size in Spain, in USD million (2019-2032)
Table 11: VX-121 Market Size in the UK, in USD million (2019-2032)
List of Figures
Figure 1: VX-121 Market Size in the 6MM, USD million (2019-2032)
Figure 2: VX-121 Market Size in the United States, USD million (2019-2032)
Figure 3: VX-121 Market Size in Germany, USD million (2019-2032)
Figure 4: VX-121 Market Size in France, USD million (2019-2032)
Figure 5: VX-121 Market Size in Italy, USD million (2019-2032)
Figure 6: VX-121 Market Size in Spain, USD million (2019-2032)
Figure 7: VX-121 Market Size in the United Kingdom, USD million (2019-2032)