MicroRNA Research Tools, Diagnostics and Therapeutics: Global Markets

The research study aims to thoroughly assess and analyze the miRNA research tools, diagnostics and therapeutics market; revenue forecasts; and future trends globally and provide strategic recommendations for the success of the market participants. This study focuses on the global market of miRNA tools and provides an updated review including its applications in various arenas of diagnostics and therapeutics. The report deals with miRNA tools covering technologies used in the biomedical industry. These products are miRNA quantitative reverse transcription-PCR, next-generation sequencing, microarray, fluorescent in situ hybridization, isolation and purification tools and other tools like inhibitors, probes and vectors.

The report also covers miRNA tools by end user and application. The end users for miRNA tools are categorized as academic and other research institutes, life science industry, and service sectors. The report covers market application areas, such as cancer, cardiovascular diseases, immune diseases, neurological disorders, metabolic disorders, and others (virology, liver diseases, genetic diseases among others).

The scope of the study is global. Current and projected market forecasts during the forecast period (2023 to 2028) are discussed. Figures for 2023 are estimated, except where actual results have been reported. This report includes forecasts by technology type, end user, application and region from 2023 through 2028.

The report also includes an analysis of leading and emerging competitors in the current worldwide miRNA research tools, diagnostics and therapeutics market. Profiles of manufacturers of leading products as well as biotechnology companies with novel products in development, are analyzed to define the specific product strategies employed. This report also assesses emerging trends and technologies in the market.

Report Includes

33 data tables and 43 additional tables
An up-to-date overview and industry analysis of the global markets for microRNA (miRNA) research tools, diagnostics and therapeutics
Analyses of the global market trends, with historical market revenue data (sales figures) for 2020-2022, estimates for 2023, forecasts for 2024, and projections of compound annual growth rates (CAGRs) through 2028
Estimation of the actual market size and revenue forecast for the global miRNA tools markets, and corresponding market share analysis based on technology type, application (therapeutic area), end user, and region
Updated information on key market drivers and opportunities, industry shifts and regulations, and other region and industry specific macroeconomic variables that will influence this market demand in the coming years (2023-2028)
Insight into the recent industry structure, competitive aspects of each product segments, increasing investment on R&D activities, market growth strategies, and company revenue share analysis
Review of the selected new miRNA products, research tools and diagnostics services, recent drug candidates, clinical trial applications, and new trends and developments in the biomedical industry
Examination of the extensive portfolio of miRNA pathway drug candidates, some already in Phase II clinical trials, showing promising clinical data in various arenas of diagnostics and therapeutics, including cancer, hepatitis infections, and cardiovascular diseases etc.
Identification of leading and emerging competitors in the current worldwide market for miRNA research tools, diagnostics, and therapeutics, and analysis of their competitive landscape based on recent developments and segmental revenues
Descriptive company profiles of the leading global players, including Agilent Technologies Inc., Bio-Rad Laboratories Inc., Illumina Inc., F. Hoffmann-La Roche AG, Merck KGaA, Qiagen N.V., and Thermo Fisher Scientific Inc.

Chapter 1 Introduction

Study Goals and Objectives
Reasons for Doing this Study
Scope of Report
Methodology and Information Sources
What's New in this Update?
Geographic Breakdown

Chapter 2 Summary and Highlights

Market Outlook
Highlights of the Microrna Research Tools, Diagnostics and Therapeutics Markets

Chapter 3 Market Overview

Background: Genetic Material
Types of Rna
Messenger Rna (Mrna)
Ribosomal Rna (Rrna)
Transfer Rna (Trna)
Small Interfering Rnas (Sirna)
Small Nucleolar Rna (Snorna)
Piwi-Interacting Rnas (Pirnas)
Micrornas (Mirnas)
Overview
History of Microrna Research
Biogenesis of Microrna
The Function of Microrna
Applications of Microrna
Research Tools
Microrna in Therapeutics
Microrna in Diagnostics
Bioinformatics: Applications in Microrna Research
Computational Tools
Mirdb
Targetscan
Diana-Microt-Cds
Mirtargetlink 2.0
Rna22 V2
Targetminer
Rnahybrid
Microrna Databases
Mirbase
Deepbase
Mirnamap
Plant Microrna Database (Pmrd)

Chapter 4 Market Dynamics

Market Drivers
Developments in Analytical Technologies and Assay Methods
Robust Funding Environment for Biomedical Research
Increasing Incidence of Chronic Diseases
Growing Number of Clinically Relevant Mirnas
Market Challenges
High Investment Cost
High Failure Rate
Challenges Associated With Microrna Based Therapeutics Development
Lack of Skilled Professionals

Chapter 5 Market Breakdown by Technology Type

Market Overview
Quantitative Reverse Transcription Polymerase Chain Reaction (Rt-Qpcr)
Next-Generation Sequencing (Ngs)
Microarray
Isolation and Purification Tools
In Situ Hybridization (Ish) and Northern Blotting
Other Mirna Tools
Microrna Mimics
Microrna Inhibitors
Agomirs/Antagomirs
Market Revenue by Technology Type
Rt-Qpcr
Next-Generation Sequencing (Ngs)
Microarray
Isolation and Purification Tools
In Situ Hybridization (Ish) and Northern Blotting
Other Tools

Chapter 6 Market Breakdown by End-user

Market Overview
Academic and Other Research Institutes
Life Science Industry
Therapeutics
Diagnostics
Mirna Service Providers
Market Revenue by End-user
Academic and Other Research Institutes Market, by Technology Type
Life Science Industry Market, by Technology Type
Mirna Service Providers Market, by Technology Type

Chapter 7 Market Breakdown by Application

Market Overview
Cancer
Cardiovascular Diseases
Neurological Disorders
Metabolic Diseases
Immune Disorders
Other Diseases
Market Revenue by Application
Cancer
Cardiovascular Diseases
Neurological Disorders
Metabolic Disorders
Immune Disorders
Other Diseases

Chapter 8 Market Breakdown by Region

Market Overview
Market Revenue by Region
North America
Market Revenue, by Technology Type
Europe
Market Revenue, by Technology Type
Asia-Pacific
Market Revenue, by Technology Type
Rest of the World (Row)
Market Revenue, by Technology Type

Chapter 9 Esg Development

Introduction to Esg
Sustainability in Mirna Tools and Services Industry: An Esg Perspective
Key Esg Issues
Consumer Attitudes Towards Esg
Industry Esg Performance Analysis
Case Study
Concluding Remarks

Chapter 10 Emerging Trends and Technologies

Emerging Technologies and Trends in the Market
Circulating Mirna Diagnostics for Non-Invasive Health Monitoring
Increasing Adoption of Digital Pcr (Dpcr)
Rna-Sequencing

Chapter 11 Clinical Trials Analysis

Overview
Pipeline Analysis

Chapter 12 Competitive Landscape

Overview
Leading Market Players Ranking
Mergers and Acquisitions

Chapter 13 Company Profiles

Abcam plc
Agilent Technolgies Inc.
Bio-Rad Laboratories Inc.
Cd Genomics
Danaher
F. Hoffmann-La Roche AG
Genecopoeia Inc.
Illumina Inc.
Merck Kgaa
Nanostring Technologies Inc.
Qiagen
Regulus Therapeutics
Thermo Fisher Scientific Inc.
Takara Bio Inc.

List of Tables

Summary Table: Global Market for miRNA Tools, by Technology Type, Through 2028
Table 1: Deoxyribonucleic Acid Vs. Ribonucleic Acid
Table 2: RNA Types and Their Functions
Table 3: A Comparison Among Small Molecules, Protein-based and miRNA-based Drugs
Table 4: Comparison of Various MicroRNA Detection Methods
Table 5: NIH Funding for Selected Research Categories, Through 2023
Table 6: Terminated/Suspended microRNA Drug Candidates
Table 7: NGS vs. qPCR vs. Microarrays: A Detailed Comparison
Table 8: Global Market for miRNA Tools, by Technology Type, Through 2028
Table 9: Selected Companies Developing MicroRNA Therapeutics
Table 10: miRNA-Based Diagnostic Tools Available in Clinic
Table 11: Global Market for miRNA Tools, by End User, Through 2028
Table 12: Selected Companies Offering MiRNA Expression Profiling and Other Services
Table 13: Global Market for miRNA Tools for Academic and Other Research Institutes, by Technology Type, Through 2028
Table 14: Global Market for miRNA Tools for Life Science Industry, by Technology Type, Through 2028
Table 15: Global Market for miRNA Tools for miRNA Service Providers, by Technology Type, Through 2028
Table 16: Global Market for miRNA Tools, by Application, Through 2028
Table 17: Number of Publications Associated with microRNA and Diseases, 2017-2022
Table 18: Number of microRNA Clinical Trials by Diseases, 2017-2022
Table 19: Global Market for miRNA Tools for Cancer, by Technology Type, Through 2028
Table 20: Global Market for miRNA Tools for Cardiovascular Diseases, by Technology Type, Through 2028
Table 21: NIH Funding for Neuroscience Research, Through 2023
Table 22: Global Market for miRNA Tools for Neurological Disorders, by Technology Type, Through 2028
Table 23: Global Market for miRNA Tools for Metabolic Disorders, by Technology Type, Through 2028
Table 24: Global Market for miRNA Tools for Immune Disorders, by Technology Type, Through 2028
Table 25: Global Market for miRNA Tools for Other Diseases, by Technology Type, Through 2028
Table 26: Global Market for miRNA Tools, by Region, Through 2028
Table 27: North American Market for miRNA Tools, by Technology Type, Through 2028
Table 28: European Market for miRNA Tools, by Technology Type, Through 2028
Table 29: Asia-Pacific Market for miRNA Tools, by Technology Type, Through 2028
Table 30: RoW Market for miRNA Tools, by Technology Type, Through 2028
Table 31: Key Focus Areas in ESG Metrics
Table 32: Net-Zero GHG Commitments by Major miRNA Tools Companies
Table 33: ESG Rankings for Major miRNA Tools Companies, 2023*
Table 34: CDP Scope Card for Major miRNA Tools and Services Companies, 2022
Table 35: Digital PCR vs. Real-Time qPCR vs. Traditional PCR at a Glance
Table 36: Disease Classes Addressed, by MicroRNA Therapeutics in Clinical Trials, as of May 2023
Table 37: Selected Investigational miRNA-Based Therapeutic Candidates in Clinical Trials, as of May 2023
Table 38: Selected miRNA-based Diagnostic Tests in Development, as of May 2023
Table 39: Leading Market Players in miRNA Tools Market, 2022
Table 40: Mergers and Acquisitions of MicroRNA Tools Companies, August 2018-May 2023
Table 41: Abcam Plc: Annual Revenue, 2022
Table 42: Abcam Plc: miRNA Product Portfolio
Table 43: Abcam Plc: News/Key Developments, Jan 2021-May 2023
Table 44: Agilent Technologies Inc.: Annual Revenue, 2022
Table 45: Agilent Technologies Inc.: miRNA Product Portfolio
Table 46: Agilent Technologies Inc.: News/Key Developments, Jan 2021-May 2023
Table 47: Bio-Rad Laboratories Inc.: Annual Revenue, 2022
Table 48: Bio-Rad Laboratories Inc.: miRNA Product Portfolio
Table 49: Bio-Rad Laboratories Inc.: Selected Key Developments, Jan 2020-March 2023
Table 50: Danaher: Annual Revenue, 2022
Table 51: Danaher: miRNA Product Portfolio
Table 52: Danaher: News/Key Developments, Jan 2020-May 2023
Table 53: Roche: Annual Revenue, 2022
Table 54: Roche: miRNA Product Portfolio
Table 55: Roche: News/Key Developments, Jan 2021-May 2023
Table 56: GeneCopoeia Inc.: miRNA Product Portfolio
Table 57: Illumina: Annual Revenue, 2022
Table 58: Illumina: miRNA Product Portfolio
Table 59: Illumina: News/Key Developments, Jan 2021-May 2023
Table 60: Merck KGaA: Annual Revenue, 2022
Table 61: Merck KGaA: miRNA Product Portfolio
Table 62: Merck KGaA: News/Key Developments, Jan 2021-May 2023
Table 63: NanoString Technologies Inc.: Annual Revenue, 2022
Table 64: NanoString Technologies Inc.: miRNA Product Portfolio
Table 65: NanoString Technologies Inc.: News/Key Developments, Jan 2021-May 2023
Table 66: Qiagen: Annual Revenue, 2022
Table 67: Qiagen: miRNA Product Portfolio
Table 68: Qiagen: News/Key Developments, Jan 2021-May 2023
Table 69: Regulus Therapeutics LLC: News/Key Developments, Jan 2021-May 2023
Table 70: Thermo Fisher Scientific Inc.: Segment Information
Table 71: Thermo Fisher Scientific Inc.: Annual Revenue, 2022
Table 72: Thermo Fisher Scientific Inc.: miRNA Product Portfolio
Table 73: Thermo Fisher Scientific Inc.: News/Key Developments, Jan 2021-May 2023
Table 74: Takara Bio Inc.: Annual Revenue, 2022
Table 75: Takara Bio Inc.: miRNA Product Portfolio

List of Figures

Summary Figure: Global Market for miRNA Tools, by Technology Type, 2020-2028
Figure 1: Resources for RNA/miRNA Extraction
Figure 2: Common miRNA Research Applications
Figure 3: miRNA Fundamental Research Questions
Figure 4: Bioinformatics Analysis Pipeline
Figure 5: miRNA Based Drugs in Clinical Trials, by Clinical Trail Phase
Figure 6: PubMed Article Count: MicroRNA (miRNA), 2014-2022
Figure 7: Real-time PCR microRNA Workflow
Figure 8: Workflow for miRNA Sequencing
Figure 9: miRNA Microarray Analysis Workflow
Figure 10: Steps for ISH
Figure 11: Steps for Northern Blot Analysis
Figure 12: Global Market for miRNA Tools, by Technology Type, 2020-2028
Figure 13: Global Market Shares of miRNA Tools, by Technology Type, 2022
Figure 14: Share of miRNA Active Clinical Trials, by Funder Type, as in May 2023
Figure 15: Global Market for miRNA Tools, by End User, 2020-2028
Figure 16: Global Market Shares of miRNA Tools, by End User, 2022
Figure 17: Global Market for miRNA Tools for Academic and Other Research Institutes, by Technology Type, 2020-2028
Figure 18: Global Market Shares of miRNA Tools for Academic and Other Research Institutes, by Technology Type, 2022
Figure 19: Global Market for miRNA Tools for Life Science Industry, by Technology Type, 2020-2028
Figure 20: Global Market Shares of miRNA Tools for Life Science Industry, by Technology Type, 2022
Figure 21: Global Market for miRNA Tools for miRNA Service Providers, by Technology Type, 2020-2028
Figure 22: Global Market Shares of miRNA Tools for miRNA Service Providers, by Technology Type, 2022
Figure 23: Global Market for miRNA Tools, by Application, 2020-2028
Figure 24: Global Market Shares of miRNA Tools, by Application, 2022
Figure 25: Global Market for miRNA Tools for Cancer, by Technology Type, 2020-2028
Figure 26: Global Market for miRNA Tools for Cardiovascular Diseases, by Technology Type, 2020-2028
Figure 27: NIH’s AD and Related Dementia Research Funding, 2013-2023
Figure 28: Global Market for miRNA Tools for Neurological Disorders, by Technology Type, 2020-2028
Figure 29: Global Market for miRNA Tools for Metabolic Disorders, by Technology Type, 2020-2028
Figure 30: Global Market for miRNA Tools for Immune Disorders, by Technology Type, 2020-2028
Figure 31: Global Market for miRNA Tools for Other Diseases, by Technology Type, 2020-2028
Figure 32: Global Market for miRNA Tools, by Region, 2020-2028
Figure 33: Global Market Shares of miRNA Tools, by Region, 2022
Figure 34: Business Enterprise Expenditures on Pharmaceutical R&D and Government Budgets for Health-related R&D, 2018 (or Nearest Year)
Figure 35: North American Market for miRNA Tools, by Technology Type, 2020-2028
Figure 36: North American Market Shares of miRNA Tools, by Technology Type, 2022
Figure 37: Investment on Grants for Biomedical Research, by Region, 2020
Figure 38: European Market for miRNA Tools, by Technology Type, 2020-2028
Figure 39: European Market Shares of miRNA Tools, by Technology Type, 2022
Figure 40: Asia-Pacific Market for miRNA Tools, by Technology Type, 2020-2028
Figure 41: Asia-Pacific Market Shares of miRNA Tools, by Technology Type, 2022
Figure 42: RoW Market for miRNA Tools, by Technology Type, 2020-2028
Figure 43: RoW Market Shares of miRNA Tools, by Technology Type, 2022
Figure 44: How a Strong ESG Proposition Benefits Businesses
Figure 45: ESG-Adoption Level Across All the Industries, Global, 2021 and 2022
Figure 46: The Ten Business Sustainability Trends Identified for 2022
Figure 47: Research Communities’ Key Sustainable Practices in Research Laboratories
Figure 48: Illumina Inc.’s Most Material ESG Issues
Figure 49: Emerging Trends/Technologies in the miRNA Tools Market
Figure 50: Advantages of Liquid Biopsy
Figure 51: Benefits of RNA Sequencing
Figure 52: miRNA-based Clinical Trials: “miR-”, 2014-2022
Figure 53: miRNA Based Therapeutic Candidates in Clinical Trials
Figure 54: Principle Competitive Factors in microRNA Tools Market
Figure 55: Abcam Plc: Financials, 2021 and 2022
Figure 56: Abcam Plc: Revenue Share, by Type, 2022
Figure 57: Abcam Plc: Revenue Share, by Region, 2022
Figure 58: Agilent Technologies Inc.: Financials, 2021 and 2022
Figure 59: Agilent Technologies Inc.: Market Share, by Business Segment, 2022
Figure 60: Agilent Technologies Inc.: Revenue Share, by Region, 2022
Figure 61: Bio-Rad Laboratories Inc.: Financials, 2021 and 2022
Figure 62: Bio-Rad Laboratories Inc.: Revenue Share, by Business Segment, 2022
Figure 63: Bio-Rad Laboratories Inc.: Revenue Share, by Region, 2022
Figure 64: Danaher: Financials, 2021 and 2022
Figure 65: Danaher: Revenue Share, by Business Segment, 2022
Figure 66: Danaher: Revenue Share, by Country/Region, 2022
Figure 67: Roche: Financials, 2021 and 2022
Figure 68: Roche: Revenue Share, by Business Segment, 2022
Figure 69: Illumina: Financials, 2021 and 2022
Figure 70: Illumina: Revenue Share, by Business Segment, 2022
Figure 71: Illumina: Revenue Share, by Region, 2022
Figure 72: Merck KGaA: Financials, 2021 and 2022
Figure 73: Merck KGaA: Market Share, by Business Segment, 2022
Figure 74: Merck KGaA: Revenue Share, by Region, 2022
Figure 75: NanoString Technologies Inc.: Financials, 2021 and 2022
Figure 76: NanoString Technologies Inc.: Market Share, by Business Segment, 2022
Figure 77: NanoString Technologies Inc.: Revenue Share, by Region, 2022
Figure 78: Qiagen: Financials, 2021 and 2022
Figure 79: Qiagen: Revenue Share, by Product Type, 2022
Figure 80: Qiagen: Revenue Share, by Region, 2022
Figure 81: Thermo Fisher Scientific Inc.: Financials, 2021 and 2022
Figure 82: Thermo Fisher Scientific Inc.: Revenue Share, by Business Segment, 2022
Figure 83: Thermo Fisher Scientific Inc.: Revenue Share, by Region, 2022
Figure 84: Takara Bio Inc.: Financials, 2021 and 2022
Figure 85: Takara Bio Inc.: Revenue Share, by Product, 2022
Figure 86: Takara Bio Inc.: Revenue Share, by Country/Region, 2022

Executive Summary

microRNAs (miRNAs) are noncoding RNA that play pivotal role in gene silencing and posttranscriptional regulation of gene expression. Studies have shown that thousands of human protein-coding genes are regulated by miRNAs, indicating that miRNAs have regulatory roles in diverse cellular functions, such as apoptosis, proliferation and differentiation - all of which have shown to be contributing factor in diseases such as cancer and cardiovascular conditions. These features make it a potential diagnostic and therapeutic candidate. Currently, more than 2,500 mature microRNAs have been identified in the human genome. An important factor for success in miRNA research is access to high-performance tools and technologies.

Several tools and technologies are used in the miRNA research continuum, from isolation through discovery, profiling, quantitation, validation and functional analysis. Sensitive and advanced laboratory analysis methods [quantitative reverse transcription polymerase chain reaction (RT- qPCR), next-generation sequencing (NGS), and microarray] and tools (probes, reagents, and kits) for miRNA isolation, discovery, profiling, quantitation, validation and functional analysis are being largely used globally.

Most known miRNAs have been identified by random cloning and sequencing. There is an estimated 0.01% chance of uncovering a unique miRNA using this method - thus making discovery efforts very time-consuming and laborious. Recent studies have focused on bioinformatics, where algorithms predict miRNAs based on the presence of hairpins and other structures associated with the presence of miRNAs.

The miRNA tools market has observed moderate growth recently and is predicted to grow at a CAGR of 5.9% from 2023 to 2028. The need for new research tools is constant as users deepen scientific understanding and search for the next breakthrough. MiRNA profiling is quickly becoming a promising technique in many research fields, such as translational research. It can provide useful information on the role of miRNAs in the pathogenesis of human diseases such as cancers, metabolic diseases, neurological disorders and infectious diseases.

The miRNA tools market growth is attributed to increased research at the genetic level, increased use of miRNA for therapeutic and diagnostic research purposes, the rise in R&D funding, and increased demand for advanced analysis techniques and assay methods. Microarray technology and the advent of NGS in the early 2000s significantly broadened our understanding of miRNAs and introduced new opportunities for clinical applications.

Companies Mentioned

Abcam plc
Agilent Technolgies Inc.
Bio-Rad Laboratories Inc.
Cd Genomics
Danaher
F. Hoffmann-La Roche AG
Genecopoeia Inc.
Illumina Inc.
Merck Kgaa
Nanostring Technologies Inc.
Qiagen
Regulus Therapeutics
Thermo Fisher Scientific Inc.
Takara Bio Inc.

Table Information

Report Attribute	Details
No. of Pages	200
Published	July 2023
Forecast Period	2023 - 2028
Estimated Market Value ( USD ) in 2023	$ 664.2 Million
Forecasted Market Value ( USD ) by 2028	$ 883 Million
Compound Annual Growth Rate	5.9%
Regions Covered	Global
No. of Companies Mentioned	14

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Report Includes

Table of Contents

Executive Summary

Companies Mentioned

Table Information

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