Global Gene Synthesis Market Report and Forecast 2023-2031

The global gene synthesis market attained a value of USD 2 billion in 2022, driven by increasing demand for customized genes and advancements in gene synthesis technologies. The market is expected to grow at a CAGR of 21.18% during the forecast period of 2023-2031 to attain a value of USD 10.2 billion by 2031.

Gene Synthesis: Introduction

Gene synthesis is a laboratory technique that involves artificially creating DNA sequences corresponding to specific genes or genetic elements. It allows to produce custom-designed DNA molecules with precise nucleotide sequences. Gene synthesis has numerous uses and offers several benefits in various fields of research and applications.

The uses of gene synthesis include:

• Gene Function Studies: Gene synthesis enables the production of specific DNA sequences for studying gene function and understanding biological processes. Scientists can design and synthesize genes of interest to investigate their roles in cellular functions, disease mechanisms, and developmental processes
• Protein Expression and Engineering: Gene synthesis plays a vital role in protein expression and engineering. By synthesizing genes encoding desired proteins, researchers can optimize protein expression levels, modify protein sequences to enhance stability or functionality, and generate variants for structure-function studies or therapeutic applications
• Vaccine Development: Gene synthesis is used in the development of vaccines. Researchers can synthesize genes encoding viral or bacterial antigens, enabling the production of recombinant proteins or DNA vaccines for immunization studies and vaccine development against infectious diseases
• Genetic Engineering and Biotechnology: Gene synthesis is fundamental in genetic engineering and biotechnology. It enables the creation of recombinant DNA constructs, synthetic gene circuits, and engineered genetic pathways for various applications such as metabolic engineering, biofuel production, biopharmaceutical production, and bioremediation
• Synthetic Biology: Gene synthesis is at the core of synthetic biology, allowing scientists to design and build artificial gene networks, genetic circuits, and entire synthetic genomes. This field aims to engineer novel biological systems with desired functions and properties, leading to applications in biotechnology, bioengineering, and even the creation of synthetic organisms

The benefits of gene synthesis include:

• Customization and Design: Gene synthesis offers customization and design flexibility, allowing researchers to create DNA sequences with precise nucleotide sequences. This enables the generation of genes optimized for specific applications, incorporating desired modifications, codon usage preferences, regulatory elements, or other functional elements
• Time and Cost Efficiency: Gene synthesis provides a more efficient and cost-effective alternative to traditional cloning methods for obtaining specific DNA sequences. It eliminates the need for time-consuming and labour-intensive cloning steps, reducing research and development timelines and costs associated with gene manipulation
• Access to Rare or Non-Natural Genes: Gene synthesis allows access to rare or non-natural genes that may be difficult to obtain from natural sources. Researchers can synthesize genes from diverse organisms, obtain genes with rare codon usage patterns, or design non-natural genetic sequences to explore new functions or properties
• Error Correction and Optimization: Gene synthesis technologies include error correction mechanisms to ensure high-quality DNA sequences. This minimizes sequence errors, mutations, or other artifacts commonly encountered in traditional cloning approaches, leading to more reliable and reproducible results
• Accelerated Research and Innovation: Gene synthesis accelerates research and innovation by providing quick access to customized DNA sequences. Researchers can rapidly obtain genes of interest, allowing them to focus on downstream experiments, hypothesis testing, and advancing scientific discoveries or product development

It is important to note that ethical considerations, biosafety guidelines, and intellectual property regulations should be followed when utilizing gene synthesis techniques, especially in applications involving genetically modified organisms or potential biohazards.

Gene Synthesis Market Segmentations

The market can be categorised into components, gene therapy, application, synthesis type, and region.

Market Breakup by Components

• Synthesizer
• Consumables
• Software and Services

Market Breakup by Gene Therapy

• Standard Gene
• Express Gene
• Complex Gene
• Others

Market Breakup by Application

• Synthetic Biology
• Genetic Engineering
• Vaccine Design
• Therapeutics Antibodies
• Others

Market Breakup by Gene Synthesis Type

• Gene Library Synthesis
• Solid Phase Synthesis
• Chip-Based DNA Synthesis
• PCR-Based Enzyme Synthesis

Gene Synthesis Market Breakup by Region

• North America
• Europe
• Asia Pacific
• Latin America
• Middle East and Africa

Gene Synthesis Market Overview

The gene synthesis market has experienced significant growth and is projected to continue expanding in the coming years. Several factors contribute to the positive market scenario.

One of the primary drivers of market growth is the increasing demand for synthetic genes in various fields of research and applications. Advancements in genetic engineering, biotechnology, and synthetic biology have led to a growing need for custom-designed DNA sequences. Gene synthesis enables researchers to obtain specific genes with precise nucleotide sequences, facilitating studies on gene function, protein expression, vaccine development, genetic engineering, and synthetic biology. The expanding applications of gene synthesis across these fields drive market demand.

Moreover, technological advancements in gene synthesis techniques have played a crucial role in market expansion. The development of high-throughput synthesis platforms, improved error correction mechanisms, and optimization algorithms has enhanced the efficiency, accuracy, and scalability of gene synthesis. These advancements have reduced turnaround times, improved sequence quality, and lowered costs, making gene synthesis more accessible and appealing to researchers and industry professionals.

In conclusion, the gene synthesis market is poised for significant growth due to the increasing demand for custom-designed DNA sequences, technological advancements, the availability of gene synthesis services, and the expanding applications in genetic engineering and synthetic biology. As the need for rapid access to customized genes and synthetic DNA sequences continues to rise, there will be a focus on further improving synthesis efficiency, reducing costs, and expanding the range of available gene synthesis services. Continued investment in research and development, advancements in synthesis technologies, and collaborations between industry and academia will shape the future of the gene synthesis market.

Key players in the global gene synthesis Market

The key features of the market report include patent analysis, grants analysis, clinical trials analysis, funding and investment analysis, partnerships, and collaborations analysis by the leading key players. The major companies in the gene synthesis market are as follows:

• ATDBio Ltd
• General Biosystems
• Macrogen CO
• Boster Biological Technology
• Creative Biogene
• Bioneer Pacific,
• Exonbio
• trenzyme GmbH
• Twist Bioscience
• BioCat GmbH
• OriGene Technologies, Inc
• Integrated DNA Technologies
• Eurofins Scientific
• NZYTech
• Genes and Enzymes

*The publisher always strives to provide you with the latest information. The numbers in the article are only indicative and may be different from the actual report.