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Protein Purification and Isolation Market: Global Industry Analysis, Trends, Market Size, and Forecasts up to 2030

  • Report

  • 300 Pages
  • August 2023
  • Region: Global
  • Infinium Global Research
  • ID: 5876129
Description Jump to:
The report on the global protein purification and isolation market provides qualitative and quantitative analysis for the period from 2021-2030. The global protein purification and isolation market was valued at around USD 7804.0 million in 2022 and is expected to reach USD 19553.1 million in 2030, with a CAGR of 10.6% during the forecast period 2023-2030. The study on protein purification and isolation market covers the analysis of the leading geographies such as North America, Europe, Asia Pacific, and RoW for the period of 2021-2030.

Protein purification is a set of procedures designed to separate out a single protein or a small number of proteins from a complicated mixture, typically cells, tissues, or entire organisms. The specification of a protein's structure, function, and connections depends on its purification. The target protein will subsequently be isolated from all other proteins after the purification procedure separates the mixture's protein and non-protein components. To avoid contaminants from affecting the research of a protein's structure and function, it is ideal to isolate a protein of interest from other cell components before examining it. Additionally, the protein purification and isolation industry was a flourishing industry in the economy due to the increased need for high-quality proteins in multiple research, diagnostic, and therapeutic applications. The purification and isolation methods covered by the market included chromatography, electrophoresis, ultrafiltration, and centrifugation. The market was growing as a result of elements such as biotechnology developments, rising R&D spending, and the development of the pharmaceutical and biotechnology industries. The need for isolated and purified proteins was also fuelled by the increased incidence of chronic diseases and the need for personalized therapy. Biotechnology firms, academic institutions, and contract manufacturing businesses were among the major market participants, each of which provided a wide range of goods and services.

The global protein purification and isolation market is bifurcated by product type, technology, application, and end user. By technology, the segment is further bifurcated into ultrafiltration, precipitation, chromatography, electrophoresis, western blotting, and others. The ultrafiltration segment is anticipated to have a significant impact on market growth during the forecast period. Ultrafiltration (UF) is a technique used to remove dissolved molecules and incredibly minute particles from fluids. Molecular size serves as the main basis for separation, while the sample's chemical, molecular, or electrostatic characteristics may also have an impact on the filter's permeability. Molecules must be at least an order of magnitude apart in size and have a molecular weight between 1 KDA and 1000 KDA to be separated by ultrafiltration. The filtrate, or solution that has passed through the filter, can be cleaned using ultrafiltration membranes, and the retentate, or substance that the filter has retained, can be collected. The benefits of ultrafiltration and the widespread use of ultrafiltration for protein purification and isolation are the main factors influencing the segment's growth during the anticipated period. For instance, according to the MDPI in 2021, proteins in their concentrated forms, such as isolates, could be advantageous, and a variety of protein sources can benefit from membrane filtration techniques like ultrafiltration. The usage of ultrafiltration is also growing as a result of its benefits, including its high product throughput and ability to produce results quickly. Ultrafiltration is gaining popularity as a result of its ability to overcome the drawbacks of existing techniques like chromatography, which produce poor throughputs of product at extremely high costs and need complicated instrumentation support to operate well. Therefore, over the forecast period significant segment expansion is anticipated as a result of the aforementioned causes.

The global protein purification and isolation market is segmented into Asia Pacific, North America, Europe, the Middle East & Africa, and Latin America. North America is dominating region within the global market share. An established and sophisticated healthcare system in North America underpins significant pharmaceutical and biotechnology research and development efforts. An additional factor in the region's dominance is the presence of significant pharmaceutical businesses and research facilities. Increased research activity and rising governmental and private sector investments in R&D are some of the reasons contributing to the growth. For instance, according to Research America in 2022, the United States is expected to invest USD 245,127 million in 2020 in medical and health R&D, up from USD 221,438 million in 2019. Additionally, it stated that industrial players are now investing more money in R&D than they did in past years. The amount invested by the industry in 2020 was USD 161,766 million, compared to USD 148,205 million in 2019. Consequently, rising investment shows that both the public and private sectors are putting emphasis on creating novel and cutting-edge products which anticipated the growth of protein purification and isolation market.

Report Findings

1) Drivers

  • Increasing demand for pure and active proteins for various applications in biotechnology, medicine, and research drives the market growth.
  • Advancement in technology, such as chromatography, electrophoresis, and filtration techniques, have led to improved isolation processes, boosting market growth.

2) Restraints

  • The inherent complexity of biological samples makes the purification process time-consuming and resource-intensive restraining the market growth.

3) Opportunities

  • The increasing demand for personalized medicine and precision therapeutics presents an exciting opportunity for protein purification and isolation.

Research Methodology

A) Primary Research

The primary research involves extensive interviews and analysis of the opinions provided by the primary respondents. The primary research starts with identifying and approaching the primary respondents.

The primary respondents are approached include

1. Key Opinion Leaders
2. Internal and External subject matter experts
3. Professionals and participants from the industry

The primary research respondents typically include

1. Executives working with leading companies in the market under review
2. Product/brand/marketing managers
3. CXO level executives
4. Regional/zonal/country managers
5. Vice President level executives.

B) Secondary Research

Secondary research involves extensive exploring through the secondary sources of information available in both the public domain and paid sources. Each research study is based on over 500 hours of secondary research accompanied by primary research. The information obtained through the secondary sources is validated through the crosscheck on various data sources.

The secondary sources of the data typically include

1. Company reports and publications
2. Government/institutional publications
3. Trade and associations journals
4. Databases such as WTO, OECD, World Bank, and among others.
5. Websites and publications by research agencies

Segment Covered

The global protein purification and isolation market is segmented on the basis of product type, technology, application, and end-use.

The Global Protein Purification and Isolation Market by Product Type

  • Instruments
  • Kits
  • Reagents
  • Columns
  • Others

The Global Protein Purification and Isolation Market by Technology

  • Ultrafiltration
  • Precipitation
  • Chromatography
  • Electrophoresis
  • Western Blotting

The Global Protein Purification and Isolation Market by Application

  • Drug Screening
  • Biomarker Discovery
  • Protein-protein Interaction Studies
  • Diagnostics

The Global Protein Purification and Isolation Market by End-use

  • Academic and Research Institutes
  • Hospitals
  • Pharmaceutical and Biotechnological Companies
  • Others

Company Profiles

The companies covered in the report include
  • Thermo Fisher Scientific Inc.
  • Bio-Rad Laboratories, Inc.
  • Merck Millipore (acquired by Merck kGaA)
  • QIAGEN
  • Agilent Technologies, Inc.
  • Promega Corporation
  • Sigma-Aldrich Corporation (acquired by Merck Group)
  • Purolite
  • Roche Life Sciences
  • Cytiva

What does this Report Deliver?

1. Comprehensive analysis of the global as well as regional markets of the protein purification and isolation market.
2. Complete coverage of all the segments in the protein purification and isolation market to analyze the trends, developments in the global market and forecast of market size up to 2030.
3. Comprehensive analysis of the companies operating in the global protein purification and isolation market. The company profile includes analysis of product portfolio, revenue, SWOT analysis and latest developments of the company.
4. Growth Matrix presents an analysis of the product segments and geographies that market players should focus to invest, consolidate, expand and/or diversify.

Table of Contents

Chapter 1. Preface
1.1. Report Description
1.2. Research Methods
1.3. Research Approaches
Chapter 2. Executive Summary
2.1. Protein Purification and Isolation Market Highlights
2.2. Protein Purification and Isolation Market Projection
2.3. Protein Purification and Isolation Market Regional Highlights
Chapter 3. Global Protein Purification and Isolation Market Overview
3.1. Introduction
3.2. Market Dynamics
3.2.1. Drivers
3.2.2. Restraints
3.2.3. Opportunities
3.3. Porter's Five Forces Analysis
3.4. Growth Matrix Analysis
3.4.1. Growth Matrix Analysis by Product Type
3.4.2. Growth Matrix Analysis by Technology
3.4.3. Growth Matrix Analysis by Application
3.4.4. Growth Matrix Analysis by End-use
3.4.5. Growth Matrix Analysis by Region
3.5. Value Chain Analysis of Protein Purification and Isolation Market
Chapter 4. Protein Purification and Isolation Market Macro Indicator Analysis
Chapter 5. Company Profiles and Competitive Landscape
5.1. Competitive Landscape in the Global Protein Purification and Isolation Market
5.2. Companies Profiles
5.2.1. Thermo Fisher Scientific Inc.
5.2.2. Bio-Rad Laboratories, Inc.
5.2.3. Merck Millipore (acquired by Merck kGaA)
5.2.4. QIAGEN
5.2.5. Agilent Technologies, Inc.
5.2.6. Promega Corporation
5.2.7. Sigma-Aldrich Corporation (acquired by Merck Group)
5.2.8. Purolite
5.2.9. Roche Life Sciences
5.2.10. Cytiva
Chapter 6. Global Protein Purification and Isolation Market by Product Type
6.1. Instruments
6.2. Kits
6.3. Reagents
6.4. Columns
6.5. Others
Chapter 7. Global Protein Purification and Isolation Market by Technology
7.1. Ultrafiltration
7.2. Precipitation
7.3. Chromatography
7.4. Electrophoresis
7.5. Western Blotting
Chapter 8. Global Protein Purification and Isolation Market by Application
8.1. Drug Screening
8.2. Biomarker Discovery
8.3. Protein-protein Interaction Studies
8.4. Diagnostics
Chapter 9. Global Protein Purification and Isolation Market by End-use
9.1. Academic and Research Institutes
9.2. Hospitals
9.3. Pharmaceutical and Biotechnological Companies
9.4. Others
Chapter 10. Global Protein Purification and Isolation Market by Region 2023-2030
10.1. North America
10.1.1. North America Protein Purification and Isolation Market by Product Type
10.1.2. North America Protein Purification and Isolation Market by Technology
10.1.3. North America Protein Purification and Isolation Market by Application
10.1.4. North America Protein Purification and Isolation Market by End-use
10.1.5. North America Protein Purification and Isolation Market by Country
10.1.5.1. The U.S. Protein Purification and Isolation Market
10.1.5.1.1. The U.S. Protein Purification and Isolation Market by Product Type
10.1.5.1.2. The U.S. Protein Purification and Isolation Market by Technology
10.1.5.1.3. The U.S. Protein Purification and Isolation Market by Application
10.1.5.1.4. The U.S. Protein Purification and Isolation Market by End-use
10.1.5.2. Canada Protein Purification and Isolation Market
10.1.5.2.1. Canada Protein Purification and Isolation Market by Product Type
10.1.5.2.2. Canada Protein Purification and Isolation Market by Technology
10.1.5.2.3. Canada Protein Purification and Isolation Market by Application
10.1.5.2.4. Canada Protein Purification and Isolation Market by End-use
10.1.5.3. Mexico Protein Purification and Isolation Market
10.1.5.3.1. Mexico Protein Purification and Isolation Market by Product Type
10.1.5.3.2. Mexico Protein Purification and Isolation Market by Technology
10.1.5.3.3. Mexico Protein Purification and Isolation Market by Application
10.1.5.3.4. Mexico Protein Purification and Isolation Market by End-use
10.2. Europe
10.2.1. Europe Protein Purification and Isolation Market by Product Type
10.2.2. Europe Protein Purification and Isolation Market by Technology
10.2.3. Europe Protein Purification and Isolation Market by Application
10.2.4. Europe Protein Purification and Isolation Market by End-use
10.2.5. Europe Protein Purification and Isolation Market by Country
10.2.5.1. Germany Protein Purification and Isolation Market
10.2.5.1.1. Germany Protein Purification and Isolation Market by Product Type
10.2.5.1.2. Germany Protein Purification and Isolation Market by Technology
10.2.5.1.3. Germany Protein Purification and Isolation Market by Application
10.2.5.1.4. Germany Protein Purification and Isolation Market by End-use
10.2.5.2. United Kingdom Protein Purification and Isolation Market
10.2.5.2.1. United Kingdom Protein Purification and Isolation Market by Product Type
10.2.5.2.2. United Kingdom Protein Purification and Isolation Market by Technology
10.2.5.2.3. United Kingdom Protein Purification and Isolation Market by Application
10.2.5.2.4. United Kingdom Protein Purification and Isolation Market by End-use
10.2.5.3. France Protein Purification and Isolation Market
10.2.5.3.1. France Protein Purification and Isolation Market by Product Type
10.2.5.3.2. France Protein Purification and Isolation Market by Technology
10.2.5.3.3. France Protein Purification and Isolation Market by Application
10.2.5.3.4. France Protein Purification and Isolation Market by End-use
10.2.5.4. Italy Protein Purification and Isolation Market
10.2.5.4.1. Italy Protein Purification and Isolation Market by Product Type
10.2.5.4.2. Italy Protein Purification and Isolation Market by Technology
10.2.5.4.3. Italy Protein Purification and Isolation Market by Application
10.2.5.4.4. Italy Protein Purification and Isolation Market by End-use
10.2.5.5. Rest of Europe Protein Purification and Isolation Market
10.2.5.5.1. Rest of Europe Protein Purification and Isolation Market by Product Type
10.2.5.5.2. Rest of Europe Protein Purification and Isolation Market by Technology
10.2.5.5.3. Rest of Europe Protein Purification and Isolation Market by Application
10.2.5.5.4. Rest of Europe Protein Purification and Isolation Market by End-use
10.3. Asia Pacific
10.3.1. Asia Pacific Protein Purification and Isolation Market by Product Type
10.3.2. Asia Pacific Protein Purification and Isolation Market by Technology
10.3.3. Asia Pacific Protein Purification and Isolation Market by Application
10.3.4. Asia Pacific Protein Purification and Isolation Market by End-use
10.3.5. Asia Pacific Protein Purification and Isolation Market by Country
10.3.5.1. China Protein Purification and Isolation Market
10.3.5.1.1. China Protein Purification and Isolation Market by Product Type
10.3.5.1.2. China Protein Purification and Isolation Market by Technology
10.3.5.1.3. China Protein Purification and Isolation Market by Application
10.3.5.1.4. China Protein Purification and Isolation Market by End-use
10.3.5.2. Japan Protein Purification and Isolation Market
10.3.5.2.1. Japan Protein Purification and Isolation Market by Product Type
10.3.5.2.2. Japan Protein Purification and Isolation Market by Technology
10.3.5.2.3. Japan Protein Purification and Isolation Market by Application
10.3.5.2.4. Japan Protein Purification and Isolation Market by End-use
10.3.5.3. India Protein Purification and Isolation Market
10.3.5.3.1. India Protein Purification and Isolation Market by Product Type
10.3.5.3.2. India Protein Purification and Isolation Market by Technology
10.3.5.3.3. India Protein Purification and Isolation Market by Application
10.3.5.3.4. India Protein Purification and Isolation Market by End-use
10.3.5.4. South Korea Protein Purification and Isolation Market
10.3.5.4.1. South Korea Protein Purification and Isolation Market by Product Type
10.3.5.4.2. South Korea Protein Purification and Isolation Market by Technology
10.3.5.4.3. South Korea Protein Purification and Isolation Market by Application
10.3.5.4.4. South Korea Protein Purification and Isolation Market by End-use
10.3.5.5. Australia Protein Purification and Isolation Market
10.3.5.5.1. Australia Protein Purification and Isolation Market by Product Type
10.3.5.5.2. Australia Protein Purification and Isolation Market by Technology
10.3.5.5.3. Australia Protein Purification and Isolation Market by Application
10.3.5.5.4. Australia Protein Purification and Isolation Market by End-use
10.3.5.6. Rest of Asia-Pacific Protein Purification and Isolation Market
10.3.5.6.1. Rest of Asia-Pacific Protein Purification and Isolation Market by Product Type
10.3.5.6.2. Rest of Asia-Pacific Protein Purification and Isolation Market by Technology
10.3.5.6.3. Rest of Asia-Pacific Protein Purification and Isolation Market by Application
10.3.5.6.4. Rest of Asia-Pacific Protein Purification and Isolation Market by End-use
10.4. RoW
10.4.1. RoW Protein Purification and Isolation Market by Product Type
10.4.2. RoW Protein Purification and Isolation Market by Technology
10.4.3. RoW Protein Purification and Isolation Market by Application
10.4.4. RoW Protein Purification and Isolation Market by End-use
10.4.5. RoW Protein Purification and Isolation Market by Sub-region
10.4.5.1. Latin America Protein Purification and Isolation Market
10.4.5.1.1. Latin America Protein Purification and Isolation Market by Product Type
10.4.5.1.2. Latin America Protein Purification and Isolation Market by Technology
10.4.5.1.3. Latin America Protein Purification and Isolation Market by Application
10.4.5.1.4. Latin America Protein Purification and Isolation Market by End-use
10.4.5.2. Middle East Protein Purification and Isolation Market
10.4.5.2.1. Middle East Protein Purification and Isolation Market by Product Type
10.4.5.2.2. Middle East Protein Purification and Isolation Market by Technology
10.4.5.2.3. Middle East Protein Purification and Isolation Market by Application
10.4.5.2.4. Middle East Protein Purification and Isolation Market by End-use
10.4.5.3. Africa Protein Purification and Isolation Market
10.4.5.3.1. Africa Protein Purification and Isolation Market by Product Type
10.4.5.3.2. Africa Protein Purification and Isolation Market by Technology
10.4.5.3.3. Africa Protein Purification and Isolation Market by Application
10.4.5.3.4. Africa Protein Purification and Isolation Market by End-use

Companies Mentioned

  • Thermo Fisher Scientific Inc.
  • Bio-Rad Laboratories, Inc.
  • Merck Millipore (acquired by Merck kGaA)
  • QIAGEN
  • Agilent Technologies, Inc.
  • Promega Corporation
  • Sigma-Aldrich Corporation (acquired by Merck Group)
  • Purolite
  • Roche Life Sciences
  • Cytiva

Table Information

Report AttributeDetails
No. of Pages300
PublishedAugust 2023
Forecast Period2022 - 2030
Estimated Market Value in 2022 7804 Million
Forecasted Market Value by 2030 19553.1 Million
Compound Annual Growth Rate10.6%
Regions CoveredGlobal
No. of Companies Mentioned10

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