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Male Infertility. Management of Infertile Men in Reproductive Medicine

  • Book

  • April 2024
  • Elsevier Health Science
  • ID: 5879358
Despite the fact that about half of infertility problems stem from male factors, gynecologists are often the first health care providers to perform the initial assessment of the infertile couple. For this reason, it is critical that gynecologists and reproductive medicine specialists remain up to date on the primary conditions that cause male infertility, as well as current diagnostic tools and treatment options of both natural and assisted conception. From diagnosis through treatment, Male Infertility: Management of Infertile Men in Reproductive Medicine offers expert, straightforward guidance on the pathophysiology and management of male infertility for clinicians who assist couples early in the process of trying to conceive.
  • Covers diagnostic aspects of male infertility (clinical, laboratory, and imaging methods) as well as various therapeutic options including classical and advanced surgical procedures.
  • Discusses intrauterine insemination, conventional in vitro fertilization, intracytoplasmic sperm injection, sperm cryopreservation, preimplantation genetic testing, and more.
  • Begins each chapter with key points and ends with clinical scenarios of real-life problems and their solutions.
  • Shares the knowledge and expertise of global experts in the field.
  • An eBook version is included with purchase. The eBook allows you to access all of the text, figures, and references, with the ability to search, customize your content, make notes and highlights, and have content read aloud. Any additional digital ancillary content may publish up to 6 weeks following the publication date.

Table of Contents

SECTION 1 Definition, Epidemiology, and Implications of Male Infertility
1 Definition, Epidemiology, and Implications of Male Infertility
SECTION 2 Causes of Male Infertility
2 Pretesticular Causes of Male Infertility
3 Testicular Causes of Male Infertility
4 Posttesticular Causes of Male Infertility
5 Environmental/Lifestyle Factors and Male Infertility
6 Idiopathic Male Infertility
SECTION 3 Diagnosis of Male Infertility
7 Medical History and Physical Examination of Infertile Males
8 Basic Semen Analysis
9 Sperm DNA Fragmentation Tests
10 Genetic and Genomic Tests of Infertile Males
11 Computer-Assisted Semen Analysis
12 Seminal Oxidative Stress and Reactive Oxygen Species Testing
13 Assessment of Reproductive Hormones in Infertile Males
14 Imaging in Male Factor Infertility
SECTION 4 Medical Treatment of Male Infertility
15 Hormonal Therapy of Male Infertility
16 Antioxidants Therapy of Male Infertility
17 Antibiotic Therapy of Male Infertility
18 Alternative Therapy of Male Infertility
SECTION 5 Surgical Treatment of Male Infertility
19 Varicocele Repair in Infertile Males
20 Management of Ejaculatory Duct Obstruction
21 Surgical Sperm Retrieval and Processing for Assisted Reproductive Technology
SECTION 6 Assisted Reproduction
22 Intrauterine Insemination With Homologous Semen
23 In Vitro Fertilization/Intracytoplasmic Sperm Injection
24 Techniques for Selection of Surgically Retrieved Sperm for Intracytoplasmic Sperm Injection
25 Sperm Banking
SECTION 7 Clinical Practice Guidelines for Male Infertility
26 Guidelines of the American Society for Reproductive Medicine, American Urological Association, and European Association of Urology
27 Expert Opinion: Management of Male Infertility in the Postintracytoplasmic Sperm Injection Era
SECTION 8 Insights Into the Future of Male Infertility
28 Clinical Perspective in the Postintracyoplasmic Sperm Injection Era
29 Research Perspectives in the Postintracytoplasmic Sperm Injection Era
Index

Authors

Ashok Agarwal Head, Andrology Center, Director of Research, American Center for Reproductive Medicine, Cleveland, Ohio. Ashok Agarwal, PhD, HCLD (ABB), ELD (ACE) is the Head of Andrology Center and Director of Research at the American Center for Reproductive Medicine since 1993. He holds these positions at The Cleveland Clinic Foundation, where he is Professor of Surgery (Urology) at the Lerner College of Medicine of Case Western Reserve University. Ashok was trained in Male Infertility and Andrology at the Brigham and Women's Hospital and Harvard Medical School and later worked as Assistant Professor of Urology at Harvard from 1988 to 1992. Ashok has over 28 years of experience in directing busy male infertility diagnostic facilities and fertility preservation services. He is very well published with over 735 scientific papers and reviews in peer-reviewed scientific journals and is ranked in Scopus as the #1 author in the world in the fields of Male Infertility/Andrology and Human Assisted Reproduction, based on the number of peer-reviewed publications, citation scores (Scopus: 32,432; Google Scholar: 69,225), and h-index (Scopus: 97; Google Scholar: 128). He is currently an editor of more than 40 medical text books/manuals related to male infertility, ART, fertility preservation, DNA damage, and antioxidants and active in basic and clinical research. His laboratory has trained over 1,000 scientists, clinicians, graduate, and undergraduate students from the United States and more than 55 countries. Ashok is the recipient of over 100 grants totaling over 15 million dollars. His current research interests include proteomics of male infertility and the molecular markers of oxidative stress and DNA integrity in the pathophysiology of male reproduction. Florence Boitrelle ART and Andrology-Hospital of Poissy St. Germain, University Paris-Saclay, Paris, France. Panagiotis Drakopoulos Centre for Reproductive Medicine, Universitair Ziekenhuis Brussel, Vrije Universiteit Brussel,. Prof. Dr. Panagiotis Drakopoulos is Visiting Professor at the Centre for Reproductive Medicine (Universitair Ziekenhuis Brussel) in Belgium and Clinical & Scientific of the infertility clinic "I.R.I.S MED" in Herakion, Crete, Greece. He is recognized as a subspecialist in reproductive medicine and surgery by ESHRE (European Society of Human Reproduction and Embryology) and EBCOG (European Board & College of Obstetrics and Gynaecology). He has authored numerous articles in high indexed journals of the field, such as Fertility and Sterility and Human Reproduction. His research focuses on reproductive endocrinology as well as on poor ovarian responders and strategies to improve their outcome. Hassan Nooman Sallam Ramadan Saleh