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Malignant Mesothelioma Market - Global Forecast 2025-2032

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    Report

  • 189 Pages
  • October 2025
  • Region: Global
  • 360iResearch™
  • ID: 5889052
UP TO OFF until Jan 01st 2026
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The malignant mesothelioma market faces complex shifts in therapies, regulations, and stakeholder demand, requiring senior leaders to rely on advanced market intelligence to adapt strategies and ensure optimal competitive positioning.

Market Snapshot: Malignant Mesothelioma Market—Current Growth and Outlook

In 2024, the malignant mesothelioma market achieved a value of USD 834.43 million and is forecast to expand to USD 905.16 million in 2025, with projections reaching USD 1.60 billion by 2032. The segment is experiencing a compound annual growth rate (CAGR) of 8.53%. Key growth drivers include rising R&D investment, dynamic policy environments globally, and increasingly collaborative approaches in oncology. Companies driving innovation deliver therapies to patients with greater speed and efficiency, intensifying sector competition. As regulatory bodies partner more closely with the industry and cross-sector engagement deepens, new standards are being set for malignant mesothelioma management and treatment evolution.

Scope & Segmentation

This report empowers senior decision-makers with comprehensive analysis and actionable guidance, supporting resource allocation and early opportunity capture in the malignant mesothelioma market. Segmentation details ensure clarity for teams navigating an evolving oncology landscape.

  • Treatment Type: Chemotherapy agents—such as pemetrexed-based regimens and platinum monotherapy—immunotherapies targeting CTLA-4 and PD-1, radiotherapy, surgical interventions, and targeted therapies focusing on EGFR, mesothelin, and VEGF pathways.
  • Drug Class: Antifolates, immune checkpoint inhibitors (CTLA-4, PD-1, PD-L1), kinase inhibitors, monoclonal antibodies, and platinum-based compounds, which are foundational in both clinical development and market adoption.
  • Line of Therapy: Focus on first, second, and later-line treatments underscores the ongoing shift in therapy sequencing and broadens patient access.
  • Route of Administration: Intraperitoneal, intravenous, and oral delivery methods, each influencing accessibility and therapeutic impact in real-world settings.
  • End User: Hospital systems, specialty clinics, and ambulatory surgical centers, all crucial in care delivery and protocol standardization.
  • Geographic Coverage: Insights on the Americas, Europe, Middle East & Africa, and Asia-Pacific; granular analysis includes markets like the United States, Canada, Brazil, the United Kingdom, Germany, France, China, India, Japan, and Australia, capturing the impact of varying regulatory and commercial ecosystems.
  • Company Analysis: Profiles and competitive positioning of Bristol-Myers Squibb Company, Eli Lilly and Company, AstraZeneca PLC, Merck & Co., Inc., F. Hoffmann-La Roche Ltd., Pfizer Inc., Johnson & Johnson, Novartis AG, Takeda Pharmaceutical Company Limited, and Sanofi S.A., providing strategic benchmarks for industry stakeholders.

Key Takeaways for Senior Decision-Makers

  • Dual checkpoint inhibitors and targeted agents are reshaping standards in personalized care, aligning more directly with specific clinical profiles in malignant mesothelioma patients.
  • Increased cooperation among biopharma firms and contract research organizations accelerates late-stage development and enhances risk management, supporting the market’s competitive resilience.
  • Streamlined approval processes and orphan drug incentives improve timing for therapy launches and strengthen the business case for investment in rare oncology indications.
  • Regional dynamics—particularly in North America and Asia-Pacific—affect market access strategies, influenced by changing payer preferences and expanding industry partnerships.
  • Applying real-world data and value-based contracting optimizes pricing strategies, encourages continued payer collaboration, and supports market access amid cost variability.

Tariff Impact on Oncology Therapeutics

Recent changes to United States trade tariffs are exerting upward pressure on supply chain costs and influencing the reliability of pharmaceuticals used in malignant mesothelioma treatment. Increased duties on key active ingredients are contributing to higher manufacturing expenses and potential volatility in the procurement of both branded and generic medications. Industry participants are responding by revisiting sourcing strategies and expanding discussions with regulatory agencies to reduce disruption risk and sustain continuity of patient care.

Methodology & Data Sources

This report’s insights are built on systematic review of peer-reviewed evidence, detailed analyses of clinical trial datasets, and interviews with oncology experts, regulatory officials, and senior industry representatives. Quantitative models and scenario validation underpin robust forecasts and actionable decision support.

Why This Report Matters for the Malignant Mesothelioma Market

  • Equips R&D and commercial leaders with structured market intelligence, helping teams steer through intricate and shifting oncology market dynamics.
  • Clarifies growth opportunities and risk profiles emerging from regulatory changes, adoption of new technology, and shifting supply chain issues—enabling agile portfolio and investment strategies.
  • Provides critical competitive benchmarks to position products and operations effectively within a rapidly evolving malignant mesothelioma landscape.

Conclusion

Innovation, regulatory shifts, and cross-sector partnerships continue to influence the direction of the malignant mesothelioma market. Leveraging robust analysis will be central to strengthening competitive advantage and driving improved patient outcomes.

 

Additional Product Information:

  • Purchase of this report includes 1 year online access with quarterly updates.
  • This report can be updated on request. Please contact our Customer Experience team using the Ask a Question widget on our website.

Table of Contents

1. Preface
1.1. Objectives of the Study
1.2. Market Segmentation & Coverage
1.3. Years Considered for the Study
1.4. Currency & Pricing
1.5. Language
1.6. Stakeholders
2. Research Methodology
3. Executive Summary
4. Market Overview
5. Market Insights
5.1. Novel immunotherapy combinations showing improved survival in malignant mesothelioma patients
5.2. Adoption of mesothelin-targeted antibody-drug conjugates in late-stage clinical trials
5.3. Emergence of personalized treatment strategies leveraging genomic profiling in mesothelioma
5.4. Increasing utilization of dual checkpoint inhibitors in frontline mesothelioma treatment regimens
5.5. Growing pipeline of CAR T cell therapies targeting mesothelin for mesothelioma management
5.6. Rising focus on early diagnostic biomarkers and liquid biopsy technology in mesothelioma
5.7. Advances in photodynamic therapy applications for unresectable malignant mesothelioma
5.8. Development of multimodal treatment protocols integrating surgery radiation and systemic therapy
5.9. Heightened awareness of asbestos exposure litigation impact on mesothelioma patient enrollment
5.10. Expansion of real world evidence data sets informing treatment guidelines and reimbursement
6. Cumulative Impact of United States Tariffs 2025
7. Cumulative Impact of Artificial Intelligence 2025
8. Malignant Mesothelioma Market, by Treatment Type
8.1. Chemotherapy
8.1.1. Pemetrexed Combinations
8.1.2. Platinum Monotherapy
8.2. Immunotherapy
8.2.1. Ctla-4 Inhibitors
8.2.2. Pd-1 Inhibitors
8.3. Radiotherapy
8.4. Surgery
8.5. Targeted Therapy
8.5.1. Egfr Inhibitors
8.5.2. Mesothelin Targeted Agents
8.5.3. Vegf Inhibitors
9. Malignant Mesothelioma Market, by Drug Class
9.1. Antifolates
9.2. Immune Checkpoint Inhibitors
9.2.1. Ctla-4 Inhibitors
9.2.2. Pd-1 Inhibitors
9.2.3. Pd-l1 Inhibitors
9.3. Kinase Inhibitors
9.4. Monoclonal Antibodies
9.5. Platinum Compounds
10. Malignant Mesothelioma Market, by Line Of Therapy
10.1. First Line
10.2. Second Line
10.3. Third Line and Beyond
11. Malignant Mesothelioma Market, by Route Of Administration
11.1. Intraperitoneal
11.2. Intravenous
11.3. Oral
12. Malignant Mesothelioma Market, by End User
12.1. Ambulatory Surgical Centers
12.2. Hospitals
12.3. Specialty Clinics
13. Malignant Mesothelioma Market, by Region
13.1. Americas
13.1.1. North America
13.1.2. Latin America
13.2. Europe, Middle East & Africa
13.2.1. Europe
13.2.2. Middle East
13.2.3. Africa
13.3. Asia-Pacific
14. Malignant Mesothelioma Market, by Group
14.1. ASEAN
14.2. GCC
14.3. European Union
14.4. BRICS
14.5. G7
14.6. NATO
15. Malignant Mesothelioma Market, by Country
15.1. United States
15.2. Canada
15.3. Mexico
15.4. Brazil
15.5. United Kingdom
15.6. Germany
15.7. France
15.8. Russia
15.9. Italy
15.10. Spain
15.11. China
15.12. India
15.13. Japan
15.14. Australia
15.15. South Korea
16. Competitive Landscape
16.1. Market Share Analysis, 2024
16.2. FPNV Positioning Matrix, 2024
16.3. Competitive Analysis
16.3.1. Bristol-Myers Squibb Company
16.3.2. Eli Lilly and Company
16.3.3. AstraZeneca PLC
16.3.4. Merck & Co., Inc.
16.3.5. F. Hoffmann-La Roche Ltd.
16.3.6. Pfizer Inc.
16.3.7. Johnson & Johnson
16.3.8. Novartis AG
16.3.9. Takeda Pharmaceutical Company Limited
16.3.10. Sanofi S.A.
List of Tables
List of Figures

Samples

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Companies Mentioned

The key companies profiled in this Malignant Mesothelioma market report include:
  • Bristol-Myers Squibb Company
  • Eli Lilly and Company
  • AstraZeneca PLC
  • Merck & Co., Inc.
  • F. Hoffmann-La Roche Ltd.
  • Pfizer Inc.
  • Johnson & Johnson
  • Novartis AG
  • Takeda Pharmaceutical Company Limited
  • Sanofi S.A.

Table Information