Principles of Immunotherapy in Breast and Gastrointestinal Cancers: Activity, Mechanisms of Resistance and New Sensitization Strategies presents updated research findings on immunotherapy, with a special focus on the mechanisms of resistance of those cancer types and how to overcome them. The book discusses topics such as tumor cell-intrinsic and extrinsic mechanisms of cancer resistance to immunotherapy, the role of currently available biomarkers, strategies to overcome therapeutic resistance, sensitizing agents for cancer resistance to cell mediated immunotherapy, immunotherapeutic approaches, mechanisms of resistance, and sensitizing strategies in gastroesophageal and biliopancreatic tumors and colorectal cancer. This is a valuable resource for researchers, students, and members of the biomedical and medical fields who want to learn more about resistance to immunotherapy and how to overcome it.
Table of Contents
1. Tumor cell-intrinsic and extrinsic mechanisms of cancer resistance to immunotherapy2. Immunotherapy in breast cancer: spotlight on the pivotal role of currently available biomarkers
3. Immunotherapy for breast cancer: new strategies to enhance the patient selection and overcome therapeutic resistance
4. Sensitizing Agents for Cancer Resistance to Cell Mediated Immunotherapy in the GI tract
5. Immunotherapeutic approaches, mechanisms of resistance and sensitizing strategies in gastroesophageal tumors
6. Immunotherapeutic approaches, mechanisms of resistance and sensitizing strategies in biliopancreatic tumors
7. Immunotherapeutic approaches, mechanisms of resistance and sensitizing strategies in colorectal cancer
8. Concluding remarks and future perspectives
