OrthoBiologics provides state-of-the-art knowledge of current stem cell therapies for osteoarthritis in a single source. Current literature is dated or spread across many research articles, with coverage presented in a straightforward manner including: a historical overview, frequently used terminology, processing characteristics, outcomes of different approaches, and finally, current applications. In addition to covering current approaches and applications, the authors present ‘best practices’ for those practicing and researching osteoarthritis and stem cell treatments in this field.
Table of Contents
Section I: Introduction 1. Where Orthobiologics started: What are MSCs 2. Making Sense to Orthobiologic Terminology
Section II: Basic Science 3. Tools to identify what is in the biologic 4. Tools to identify what is in the biologic 5. Defining, optimizing and measuring PRP 6. What is obtained during bone marrow aspiration? 7. Quantitating adipose preparation 8. What is in placental products
Section III: Clinical Applications 9. Practical clinical biologic quantification 10. Optimal clinical use of PRP 11. Bone marrow aspirate and concentrate use in the clinical setting 12. Adipose tissue use in the clinical setting 13. Choosing a placental product for clinical use 14. Blood derived stem cells. Basic science and clinical significance
Section IV: The future 15. Orthobiologics on the horizon 16. The changing regulatory environment
Authors
Rachel M. Frank Assistant Professor in Orthopaedic Surgery, University of Colorado School of Medicine, USA; and Director, Joint Preservation Program and Biologics Physician Champion, Department of Orthopaedic Surgery, University of Colorado School of Medicine, USA.
Dr. Rachel Frank is a board certified orthopaedic surgeon and sports medicine specialist, focusing on the surgical and non-surgical management of knee, shoulder, and elbow injuries. She has specialized training and technical expertise in advanced knee and shoulder arthroscopy, cartilage/meniscus restoration surgery, shoulder instability surgery, and care of the female athlete. She currently serves as an Assistant Professor in Orthopaedic Surgery at the University of Colorado School of Medicine, is Director of the Joint Preservation Program and is the Biologics Physician Champion for the Department of Orthopaedic Surgery at the university. She's authored over 200 peer-reviewed journal articles, 50+ book chapters, edited 1 textbook, and presents her research both nationally and internationally at orthopaedic conferences and meetings every year. Her research has garnered dozens of prestigious national and international awards, including the prestigious American Orthopaedic Society for Sports Medicine (AOSSM) Bart Mann Award for the Advancement of Sports Medicine Research.
Jorge Chahla Assistant Professor of Orthopedic Surgery and Director of Biomechanical Research and of the International Fellowship Program, Rush University Medical Center, USA.
Dr. Jorge Chahla PhD is an orthopedic surgeon from Argentina who completed multiple fellowships (both research and clinical fellowships) at the top programs in the United States. He earned his PhD degree at the Catholic University of Argentina (UCA) with Summa Cum Laude honors. He is a complex knee and hip surgeon at Rush University Hospital, in Chicago, IL. Dr. Chahla has a strong focus on joint preservation procedures and cartilage restoration techniques with more than 250 publications in prestigious scientific journals, over 30 book chapters and 5 edited books. He has a strong reputation for his cadaveric dissections and anatomic knowledge that are imprinted in publications and books. He has recently received the AAOS Award of Excellence, AOSSM Young Investigator Award, Excellence in Research Award and the Cabaud Award (two times) from the American Orthopaedic Society for Sports Medicine. Dr. Jorge Chahla is an orthopedic surgeon who specializes in the treatment of complex knee, hip, and other sports related injuries. He's an Assistant Professor of Orthopedic Surgery at Rush?University Medical Center and serves as the Director of Biomechanical Research and of the International Fellowship Program. He's a?team physician for the Chicago White Sox (MLB), the?Chicago Bulls (NBA) and the Chicago Fire (MLS). Dr. Chahla completed several fellowships at the top programs in the United States. He is internationally recognized for his contributions to the field of sports medicine injuries through minimally invasive techniques as well as for being a pioneer in novel biological treatments. Dr. Chahla has a strong focus on joint preservation procedures and cartilage restoration techniques with more than 250 publications in prestigious scientific journals, over 30 book chapters, five edited books and presents his research both nationally and internationally at orthopedic conferences and meetings every year.
Garrett Jackson Orthopaedic Surgery Clinical Research Fellow, Midwest Orthopaedics, Rush University Medical Center, Chicago, IL, USA.
Orthopaedic Surgery Clinical Research Fellow Garrett Jackson works in Midwest Orthopaedics, Rush University Medical Center, Chicago, IL, USA.
