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Learning Deep Brain Stimulation Management through Clinical Cases

  • Book

  • August 2024
  • Elsevier Science and Technology
  • ID: 5908649

Learning Deep Brain Stimulation Management through Clinical Cases reviews the clinical practice of applying deep brain stimulation (DBS) to patients with movement disorders. The book explores the cardinal aspects of applying DBS in diverse movement disorders based on patient's needs. Every case answers all questions, providing case descriptions and step-by-step procedures for optimal replication. Every chapter includes a clinical decision support system (CDSS) depicted in flowcharts that can be used for reference. Deep Brain Stimulation (DBS) uses electrical stimulation to regulate electrical signals in neural circuits to and from identified areas in the brain to improve movement symptoms. The management of DBS in a movement disorders can be challenging, optimizing patient journeys and grasping all clinical aspects of the highly technological therapy. Hence, this book provides the informaiton necessary to embrace new breakthroughs.

Table of Contents

Pre-operative
1. Parkinson's disease: Should I receive DBS?
2. Dystonia: Is the absence of clinical evidence the evidence for an absent effect?
3. After structural damage

Post-operative: initial phase
4. Parkinson's disease: how long should I wait before the system works?
5. Tremor: the variable effect off DBS
6. Parkinson's disease: did I get sufficient effect?
7. Dystonia: how long should I wait before it works?
8. Primary non-responder

Post-operative: long term
9. Parkinson's disease: walking problems after STN DBS
10. Parkinson's disease: speech problems after STN DBS
11. Parkinson's disease: what happened to my husband?
12. secondary non-responder
13. after structural damage

Future Directions
14. How to optimally guide patients through the DBS journey?
15. Shall I go for FUS or DBS?
16. Telemedicine and future technological DBS developments
17. Expanding indications

Authors

Martijn Beudel Amsterdam University Medical Centers. Dr. Martijn Beudel is a neurologist working in the Amsterdam University Medical Centers. His main interest is neuromodulation for movement disorders. In his work, he combines clinical neurology with research on deep brain stimulation (DBS). After obtaining his PhD in functional neuro-imaging (2009), he combined his clinical training in neurology (University Medical Center Groningen) with neurophysiological research on deep brain stimulation (DBS). In 2014 and 2015 he did a post-doc on this subject at the University of Oxford in the group of prof. Peter Brown and worked on the development of a new adaptive form of DBS (aDBS) in Parkinson's disease. After finishing his training in neurology (2016) he was awarded with a fellowship of the Dutch Brain Council. This enabled him to continue to work on aDBS in Groningen. In 2018 he moved to Amsterdam to work as a consultant neurologist in the DBS team of the Amsterdam University Medical Centers. His current research focuses on the actual clinical application of aDBS, the development of neuro-physiological 'physiomarkers' that can be used for the application of aDBS and on the application of machine learning for optimizing DBS treatment in movement disorders.