Allergy and Immunology Market - Global Industry Size, Share, Trends, Opportunity, and Forecast, 2021-2031

The Global Allergy and Immunology Market is projected to expand from USD 2.81 Billion in 2025 to USD 3.96 Billion by 2031, registering a CAGR of 5.88%. This sector includes diagnostic tools, immunotherapies, and pharmaceutical interventions aimed at treating immune system disorders such as asthma, hypersensitivities, and autoimmune diseases. Growth is largely propelled by the increasing prevalence of allergic conditions worldwide, driven by urbanization and environmental pollution, as well as rising healthcare spending and broader awareness of immune health.

However, the high costs involved in developing and delivering advanced biologic therapies present a significant obstacle, potentially limiting access in developing regions. The urgency for scalable and affordable solutions is highlighted by the sheer size of the patient population; according to the Asthma and Allergy Foundation of America, over 100 million people in the United States were affected by allergic conditions in 2024, demonstrating the vast scale of the market needing economical therapeutic options.

Market Drivers

A primary catalyst for market expansion is the rising global incidence of allergic and autoimmune disorders, which is necessitating a transition from episodic symptom relief to sustained disease management. Factors such as rapid urbanization and shifting dietary habits have increased population sensitivity worldwide, making this a global health priority rather than just a Western issue. Highlighting this reach, an article in Frontiers in Nutrition from June 2024 titled 'Food allergies around the world' estimated that food allergies now impact approximately 8% of children and 10% of adults globally, prompting healthcare systems to prioritize accurate diagnostics and long-term care.

Simultaneously, the sector is being transformed by the acceleration of innovations in biologics and immunotherapies, which provide targeted treatments for the root causes of immune dysregulation. Pharmaceutical companies are heavily investing in monoclonal antibodies and desensitization therapies, evidenced by Genentech's February 2024 announcement that the U.S. FDA approved Xolair as the first medicine to reduce reactions in patients with multiple food allergies. The economic potential of these advancements is significant; AbbVie reported that its immunology portfolio generated $7.05 billion in global net revenues during the third quarter of 2024 alone, confirming the high market viability of next-generation solutions.

Market Challenges

The substantial expense required to develop and administer advanced biologic therapies stands as a major impediment to the growth of the Global Allergy and Immunology Market. The high pricing resulting from extensive research and development makes these complex treatments inaccessible for many healthcare systems in developing regions and patients with inadequate insurance. This financial barrier prevents the market from fully serving the expanding population of patients with allergic conditions, leaving a significant portion of the addressable market without access to these effective interventions.

Moreover, the existing economic burden of allergic diseases creates hesitation regarding the adoption of further high-cost treatments. Data from the Asthma and Allergy Foundation of America in 2024 indicated that the annual economic cost of asthma to the U.S. economy surpassed $82 billion, underscoring the strain on healthcare infrastructure. Consequently, payers are often reluctant to subsidize expensive biologic therapies, causing fiscal constraints that hinder the widespread expansion and adoption of these advanced immunological treatments.

Market Trends

The market is experiencing a notable shift toward Sublingual Immunotherapy (SLIT), which is becoming a preferred alternative to traditional subcutaneous injections due to its non-invasive nature and convenience for home use. This approach enhances patient compliance by removing the need for frequent clinic visits, making it highly suitable for working adults and children requiring long-term desensitization. Pharmaceutical firms are responding to this demand by increasing their offerings of standardized allergy tablets; ALK-Abelló reported in its 'Annual Report 2024' that global sales of its allergy immunotherapy tablets rose by 24% in February 2025 compared to the prior year, confirming the growing preference for oral formulations.

In addition, the integration of telehealth platforms is revolutionizing care delivery by facilitating virtual consultations and remote symptom monitoring for chronic allergy management. This digital shift helps overcome specialist shortages in rural locations and supports hybrid care models that optimize treatment protocols without necessitating physical office visits. The growing reliance on these tools is evident in a November 2025 report by the National Institutes of Health, 'TeleAllergy: Potential of Telemedicine in Management of Patients With Allergies,' which noted that 34% of allergic patients surveyed had utilized telemedicine services to manage their conditions.

Key Players Profiled in the Allergy and Immunology Market

• AbbVie Inc.
• Stallergenes Greer PLC
• Allergy Therapeutics
• Sanofi SA
• Anacor Pharmaceuticals Inc.
• Novartis International AG
• AstraZeneca
• Merck KGaA
• F. Hoffmann-La Roche Ltd.
• Johnson & Johnson
• GlaxoSmithKline PLC
• Mylan N.V.

Report Scope

In this report, the Global Allergy And Immunology Market has been segmented into the following categories:

Allergy And Immunology Market, by Treatment Type:

• Subcutaneous Immunotherapy (SCIT)
• Sublingual Immunotherapy (SLIT)
• Tablets
• Drops

Allergy And Immunology Market, by Allergy Type:

• Allergic Rhinitis
• Allergic Asthma
• Other Allergies

Allergy And Immunology Market, by Distribution Channel:

• Hospital Pharmacy
• Retail Pharmacy
• Online Pharmacy

Allergy And Immunology Market, by Region:

• North America
• Europe
• Asia-Pacific
• South America
• Middle East & Africa

Competitive Landscape

Company Profiles: Detailed analysis of the major companies present in the Global Allergy And Immunology Market.

Available Customization

The analyst offers customization according to your specific needs. The following customization options are available for the report:

• Detailed analysis and profiling of additional market players (up to five).

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