The global Anti-Vascular Endothelial Growth Factor (Anti-VEGF) Therapeutics Market is poised for steady growth, supported by increasing cases of ophthalmic disorders and rising global geriatric population. According to newly updated industry analysis by the publisher, the market is expected to grow from a valuation of US$ 12.3 Bn in 2025 to reach approximately US$ 13.3 Bn by 2032, reflecting a moderate compound annual growth rate (CAGR) of 1.09%.
As of 2025, Eylea is anticipated to remain the top revenue-generating product, owing to rising adoption in treating vision-related complications. Age-related macular degeneration, a key disease area for anti-VEGF therapies, is witnessing growing incidence, particularly among aging populations worldwide.
In the oncology segment, anti-VEGF therapeutics are gaining momentum due to their ability to inhibit tumor angiogenesis. Since many tumors show overexpression of VEGF proteins, targeted therapies using monoclonal antibodies such as bevacizumab have emerged as a significant treatment route. With cancer incidence projected to rise significantly over the coming years, the role of anti-VEGF drugs in cancer management is expected to grow.
The aging population will remain a key growth enabler. By 2050, the global population aged 60 years and above is projected to surpass 2 billion. This demographic shift is expected to substantially increase the prevalence of retinal disorders, thereby boosting demand for anti-VEGF therapies.
In Europe and Asia Pacific, increased healthcare spending, awareness programs, and adoption of advanced ophthalmic treatments are contributing to growth. Japan and the U.K., in particular, are witnessing rising demand due to their aging populations and well-established pharmaceutical industries.
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Market Insights
Anti-VEGF therapeutics are a cornerstone in the treatment of various diseases associated with abnormal blood vessel growth, such as age-related macular degeneration (AMD), diabetic retinopathy, and certain cancers. These therapeutics work by inhibiting the activity of VEGF proteins, which are responsible for promoting angiogenesis. Among the product types, Eylea continues to dominate the market, owing to its widespread clinical use and emerging drug delivery advancements.As of 2025, Eylea is anticipated to remain the top revenue-generating product, owing to rising adoption in treating vision-related complications. Age-related macular degeneration, a key disease area for anti-VEGF therapies, is witnessing growing incidence, particularly among aging populations worldwide.
Market Drivers
One of the primary drivers fueling market growth is the growing prevalence of diabetic macular edema and age-related macular degeneration, both of which are major contributors to global blindness. Anti-VEGF therapies, which are administered via intraocular injections, have proven more effective than traditional laser photocoagulation methods. As a result, these therapies are fast becoming the preferred treatment choice.In the oncology segment, anti-VEGF therapeutics are gaining momentum due to their ability to inhibit tumor angiogenesis. Since many tumors show overexpression of VEGF proteins, targeted therapies using monoclonal antibodies such as bevacizumab have emerged as a significant treatment route. With cancer incidence projected to rise significantly over the coming years, the role of anti-VEGF drugs in cancer management is expected to grow.
Business Opportunity
Despite relatively modest CAGR projections, the anti-VEGF therapeutics market continues to present strong opportunities in both developed and emerging economies. Increased investment in research and development, regulatory support, and growing awareness about early diagnosis of eye disorders provide an optimistic outlook. Additionally, the expansion of drug delivery technologies, such as pre-filled syringes and port delivery systems, are anticipated to enhance patient compliance and treatment effectiveness.The aging population will remain a key growth enabler. By 2050, the global population aged 60 years and above is projected to surpass 2 billion. This demographic shift is expected to substantially increase the prevalence of retinal disorders, thereby boosting demand for anti-VEGF therapies.
Regional Analysis
North America is projected to maintain its leading position in the global anti-VEGF therapeutics market through 2032. The region benefits from a large geriatric population, favorable reimbursement policies, and strong healthcare infrastructure. Moreover, U.S.-based companies continue to drive innovations and product approvals, making the country a lucrative hub for market growth.In Europe and Asia Pacific, increased healthcare spending, awareness programs, and adoption of advanced ophthalmic treatments are contributing to growth. Japan and the U.K., in particular, are witnessing rising demand due to their aging populations and well-established pharmaceutical industries.
Key Players
The competitive Analysis of the anti-VEGF therapeutics market includes several leading pharmaceutical companies actively focusing on research, product launches, and regulatory approvals. Major market participants include:- F. Hoffmann-La Roche Ltd.
- Biogen
- Pfizer Inc.
- Coherus BioSciences
- Amgen Inc.
- Regeneron Pharmaceuticals Inc.
- Bayer AG
- Novartis AG
Segmentation
By Product Type:
- Eylea
- Lucentis
- Beovu
By Disease Type:
- Macular Edema
- Diabetic Retinopathy
- Retinal Vein Occlusion
- Age-related Macular Degeneration
By Region:
- North America
- Latin America
- Europe
- Asia Pacific
- Middle East & Africa
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Table of Contents
1. Executive Summary
2. Market Overview
3. Global Anti-Vascular Endothelial Growth Factor Therapeutics Market Outlook, 2019-2032
4. North America Anti-Vascular Endothelial Growth Factor Therapeutics Market Outlook, 2019-2032
5. Europe Anti-Vascular Endothelial Growth Factor Therapeutics Market Outlook, 2019-2032
6. Asia Pacific Anti-Vascular Endothelial Growth Factor Therapeutics Market Outlook, 2019-2032
7. Latin America Anti-Vascular Endothelial Growth Factor Therapeutics Market Outlook, 2019-2032
8. Middle East & Africa Anti-Vascular Endothelial Growth Factor Therapeutics Market Outlook, 2019-2032
9. Competitive Landscape
10. Appendix
Companies Mentioned
- F. Hoffmann
- La Roche Ltd
- Biogen
- Pfizer Inc
- CoherusBioSciences
- Amgen Inc