In this book, world experts discuss the biochemistry of laccase and polyphenol oxidases, research methods, and uses across industries, offering a practical overview of these important enzyme classes and empowering researchers to develop their own studies and hone applications. The book deftly connects topics across these intricate enzyme systems, with early chapters on physicochemical properties of PPO and laccase, followed by separate sections on these related enzyme classes' function in biological and industrial systems, production, purification, active assays, and application areas from food and wine to healthcare, bioremediation, and green and computational chemistry.
Table of Contents
1. Introduction 2. Structural aspects and physicochemical properties of PPO and laccase Ryan Dixon 3. Functional roles of PPO Fatemeh Khodadadi, Mehdi Kamali 4. Recombinant PPO: Production, purification, and activity assays Yu Li 5. Emerging industrial applications of PPO E. Selvarajan 6. Recent advances in the design of PPO inhibitors Chen Wai Wong 7. Reaction mechanism and redox potential of laccase Nabangshu Sharma 8. Biological functions of laccases 9. Challenges and applications of laccase in bioremediation Wei-Qin Zhuang 10. Immobilization of laccase for industrial wastewater treatment: Current challenges and future Perspectives Hubert Cabana 11. Engineering of laccase through directed evolution and computational chemistry Victor Guallar
Authors
Ivanhoe K.H. Leung School of Chemistry and the Bio21 Molecular Science & Biotechnology Institute, The University of Melbourne, Australia. Dr. Leung is a Senior Lecturer in Biological Chemistry at the University of Melbourne. Dr. Leung attained his undergraduate and doctorate degrees at the University of Oxford, and began his independent research career at the University of Auckland in 2013. In 2018, he was appointed co-Deputy Director of the Centre for Green Chemistry Science at the University of Auckland. In 2021, Dr. Leung joined the University of Melbourne, where he is now part of the School of Chemistry and the Bio21 Molecular Science & Biotechnology Institute.Dr. Leung's research focusses on the study of enzyme structure, function, and modulation with an aim to help solve some of the world's most urgent challenges in health and sustainability. One of his main research interests is the study of multi-copper oxidase including polyphenol oxidase (PPO) and laccase.
