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Immune Complex Membranoproliferative Glomerulonephritis (IC - MPGN) - Epidemiology Forecast - 2034

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    Report

  • 49 Pages
  • January 2024
  • Region: Global
  • DelveInsight
  • ID: 5927504

Key Highlights

  • The total diagnosed prevalent population of Immune Complex Membranoproliferative Glomerulonephritis in the 7MM was found to be approximately 7,000 in 2023, which is expected to grow during the forecast period 2024-2034.
  • In the 7MM, the maximum cases of diagnosed prevalent cases of immune complex membranoproliferative glomerulonephritis were reported in the United States, accounting for nearly 3,800 cases in 2023.
  • Germany had the highest number of prevalent cases of immune complex membranoproliferative glomerulonephritis among EU4 and the UK, followed by Spain, whereas Italy had the lowest number of cases.
  • In 2023, Japan accounted for ~700 cases in adults and ~100 cases in pediatric population.
This “Immune Complex Membranoproliferative Glomerulonephritis (IC-MPGN) - Epidemiology Forecast - 2034” report delivers an in-depth understanding of Immune Complex Membranoproliferative Glomerulonephritis, historical and forecasted epidemiology of Immune Complex Membranoproliferative Glomerulonephritis in the United States, EU4 (Germany, France, Italy, and Spain) and the United Kingdom, and Japan.

Geography Covered

  • The United States
  • EU4 (Germany, France, Italy, and Spain) and the United Kingdom
  • Japan
Study Period: 2020-2034

Immune Complex Membranoproliferative Glomerulonephritis Disease Understanding

Immune Complex Membranoproliferative Glomerulonephritis Overview

Membranoproliferative glomerulonephritis (MPGN) is a kidney disorder involving inflammation and kidney cell changes. It is a form of glomerulonephritis caused by an abnormal immune response.

MPGN has previously been used as an umbrella term to describe a spectrum of hypocomplementemic glomerular diseases, which are a rare cause of end-stage kidney disease (ESKD). More recently, MPGN has been reclassified into two diseases: immune-complex MPGN (IC-MPGN) and C3 glomerulopathy (C3G) based on immunofluorescence findings in kidney biopsies: predominant or exclusive C3 deposits in C3G and combined immunoglobulins and complement deposits in IC-MPGN.

Immune Complex Membranoproliferative Glomerulonephritis Diagnosis

To diagnose MPGN, several tests are typically conducted including a Urine test, Blood test, Glomerular Filtration Rate (GFR) test, Kidney biopsy, and Genetic testing. These tests collectively aid in confirming the diagnosis of MPGN, determining its specific class, understanding the extent of kidney involvement, and guiding healthcare providers in formulating the most effective treatment plan based on the underlying causes and characteristics of the disease
Further details related to diagnosis are provided in the report.

Immune Complex Membranoproliferative Glomerulonephritis Epidemiology

The disease epidemiology covered in the report provides historical as well as forecasted epidemiology segmented by a total diagnosed prevalent population of Immune Complex Membranoproliferative Glomerulonephritis, gender-specific diagnosed prevalent population of Immune Complex Membranoproliferative Glomerulonephritis, and age-specific diagnosed prevalent population of Immune Complex Membranoproliferative Glomerulonephritis in the 7MM covering the United States, EU4 (Germany, France, Italy, and Spain) and the United Kingdom, and Japan from 2020 to 2034.
  • It was found that in the United States, the number of cases of male and female was ~1,900 and ~1,800 respectively, in 2023.
  • In EU4 and the UK, the diagnosed prevalence of IC-MPGN was found to be maximum in Germany with ~600 cases. While, the least number of cases were found in Italy, with ~300 cases in 2023.
  • In Japan, adults are more prevalent towards immune complex membranoproliferative glomerulonephritis compared to the pediatric group.

Scope of the Report

  • The report covers a segment of key events, an executive summary, descriptive overview of Immune Complex Membranoproliferative Glomerulonephritis, explaining its causes, signs and symptoms, pathogenesis, and diagnostic approaches.
  • Comprehensive insight has been provided into the epidemiology segments and forecasts, the future growth potential of diagnosis rate, and disease progression.
  • A detailed review of the Immune Complex Membranoproliferative Glomerulonephritis epidemiology, detailed assumptions, and rationale behind our approach is included in the report.
  • A detailed review of current challenges in establishing the diagnosis.

Immune Complex Membranoproliferative Glomerulonephritis Report Insights

  • Patient Population
  • Patient population by gender and age
  • Country-wise Epidemiology Distribution

Report Key Strengths

  • 11 Years Forecast
  • The 7MM Coverage
  • Immune Complex Membranoproliferative Glomerulonephritis Epidemiology Segmentation

Immune Complex Membranoproliferative Glomerulonephritis Report Assessment

  • Epidemiology Segmentation
  • Current Diagnostic Practices

FAQs

  • What are the disease risk and burdens and of immune complex membranoproliferative glomerulonephritis epidemiology? What will be the growth opportunities across the 7MM with respect to the patient population pertaining to immune complex membranoproliferative glomerulonephritis epidemiology?
  • What is the historical and forecasted to immune complex membranoproliferative glomerulonephritis epidemiology patient pool in the United States, EU4 (Germany, France, Italy, and Spain), the United Kingdom, and Japan?
  • Which age group is the largest contributor in patients affected with immune complex membranoproliferative glomerulonephritis epidemiology?

Reasons to Buy

  • Insights on patient burden/disease prevalence, evolution in diagnosis, and factors contributing to the change in the epidemiology of the disease during the forecast years.
  • To understand Key Opinion Leaders' perspectives around the accessibility, acceptability, and compliance-related challenges of existing treatment to overcome barriers in the future.
  • Detailed insights on various factors hampering disease diagnosis and other existing diagnostic challenges.

Table of Contents

1. Key Insights2. Report Introduction3. Executive Summary of IC-MPGN
4. IC-MPGN Epidemiology Overview at a Glance
4.1. Patient Share (%) Distribution of IC-MPGN in 2023
4.2. Patient Share (%) Distribution of IC-MPGN in 2034
5. Epidemiology Forecast Methodology
6. Disease Background and Overview
6.1. Introduction
6.2. Types
6.3. Pathogenesis
6.4. Clinical Presentation
6.5. Histological Patterns
6.6. Diagnosis
6.6.1. Kidney Disease Improving Global Outcomes (KDIGO) 2021: Guidelines for Diagnosis
6.6.2. Challenges in Diagnosis
7. Epidemiology and Patient Population
7.1. Key Findings
7.2. Assumptions and Rationales for IC-MPGN
7.3. Total Diagnosed Prevalent Population of IC-MPGN in the 7MM
7.4. The United States
7.4.1. Total Diagnosed Prevalent Population of IC-MPGN in the United States
7.4.2. Gender-specific Diagnosed Prevalent Population of IC-MPGN in the United States
7.4.3. Age-specific Diagnosed Prevalent Population of IC-MPGN in the United States
7.5. EU4 and the UK
7.5.1. Total Diagnosed Prevalent Population of IC-MPGN in EU4 and the UK
7.5.2. Gender-specific Diagnosed Prevalent Population of IC-MPGN in EU4 and the UK
7.5.3. Age-specific Diagnosed Prevalent Population of IC-MPGN in EU4 and the UK
7.6. Japan
7.6.1. Total Diagnosed Prevalent Population of IC-MPGN in Japan
7.6.2. Gender-specific Diagnosed Prevalent Population of IC-MPGN in Japan
7.6.3. Age-specific Diagnosed Prevalent Population of IC-MPGN in Japan
8. Appendix
8.1. Bibliography
8.2. Report Methodology
9. Publisher Capabilities10. Disclaimer11. About the Publisher
List of Tables
Table 1: Summary of IC-MPGN Epidemiology (2020-2034)
Table 2: Total Diagnosed Prevalent Population of IC-MPGN in the 7MM (2020-2034)
Table 3: Total Diagnosed Prevalent Population of IC-MPGN in the United States (2020-2034)
Table 4: Gender-specific Diagnosed Prevalent Population of IC-MPGN in the United States (2020-2034)
Table 5: Age-specific Diagnosed Prevalent Population of IC-MPGN in the United States (2020-2034)
Table 6: Total Diagnosed Prevalent Population of IC-MPGN in EU4 and the UK (2020-2034)
Table 7: Gender-specific Diagnosed Prevalent Population of IC-MPGN in EU4 and the UK (2020-2034)
Table 8: Age-specific Diagnosed Prevalent Population of IC-MPGN in EU4 and the UK (2020-2034)
Table 9: Total Diagnosed Prevalent Population of IC-MPGN in Japan (2020-2034)
Table 10: Gender-specific Diagnosed Prevalent Population of IC-MPGN in Japan (2020-2034)
Table 11: Age-specific Diagnosed Prevalent Population of IC-MPGN in Japan (2020-2034)
List of Figures
Figure 1: Classification of MPGN Based on Immunofluorescence Findings
Figure 2: Histological Patterns
Figure 3: Total Diagnosed Prevalent Population of IC-MPGN in the 7MM (2020-2034)
Figure 4: Total Diagnosed Prevalent Population of IC-MPGN in the United States (2020-2034)
Figure 5: Gender-specific Diagnosed Prevalent Population of IC-MPGN in the United States (2020-2034)
Figure 6: Age-specific Diagnosed Prevalent Population of IC-MPGN in the United States (2020-2034)
Figure 7: Total Diagnosed Prevalent Population of IC-MPGN in EU4 and the UK (2020-2034)
Figure 8: Gender-specific Diagnosed Prevalent Population of IC-MPGN in EU4 and the UK (2020-2034)
Figure 9: Age-specific Diagnosed Prevalent Population of IC-MPGN in EU4 and the UK (2020-2034)
Figure 10: Total Diagnosed Prevalent Population of IC-MPGN in Japan (2020-2034)
Figure 11: Gender-specific Diagnosed Prevalent Population of IC-MPGN in Japan (2020-2034)
Figure 12: Age-specific Diagnosed Prevalent Population of IC-MPGN in Japan (2020-2034)
Figure 13: Complement Activation is Implicated in Numerous Diseases