Drug Summary
Pelacarsen (TQJ230), also known as IONIS-APO(a)-LRx, AKCEA-APO(a)-LRx, and TQJ230, is an investigational antisense medicine designed to reduce apolipoprotein(a) in the liver to offer a direct approach for reducing lipoprotein(a), or Lp (a) - a very atherogenic and thrombogenic form of LDL. Elevated Lp (a) is recognized as an independent genetic cause of coronary artery disease, heart attack, stroke, and peripheral arterial disease. Currently, there is no effective drug therapy to significantly lower elevated levels of Lp (a). Lp (a) levels are determined at birth; lifestyle modification, including diet and exercise, does not impact Lp (a) levels. Even patients who can control their LDL-C remain at high risk of cardiovascular events if they have high levels of Lp (a).Pelacarsen is being developed for patients at significant risk of CVD because of their elevated Lp (a). Pelacarsen is the first drug in clinical development designed to selectively and robustly inhibit the production of Lp (a).
As per the company’s Q3 2022 investor presentation, Novartis plans filing as well as data readouts of pelacarsen in 2025.
Scope of the Report
The report provides insights into:- A comprehensive product overview including the pelacarsen description, mechanism of action, dosage and administration, research and development activities in myocardial infarction.
- Elaborated details on pelacarsen regulatory milestones and other development activities have been provided in this report.
- The report also highlights the pelacarsen research and development activities in myocardial infarction across the United States, Europe and Japan.
- The report also covers the patents information with expiry timeline around pelacarsen.
- The report contains forecasted sales of pelacarsen for myocardial infarction till 2032.
- Comprehensive coverage of the late-stage emerging therapies for myocardial infarction.
- The report also features the SWOT analysis with analyst views for pelacarsen in myocardial infarction.
Methodology
The report is built using data and information sourced primarily from internal databases, primary and secondary research and in-house analysis by the publisher’s team of industry experts. Information and data from the secondary sources have been obtained from various printable and nonprintable sources like search engines, news websites, global regulatory authorities websites, trade journals, white papers, magazines, books, trade associations, industry associations, industry portals and access to available databases.Pelacarsen Analytical Perspective
In-depth Pelacarsen Market Assessment
This report provides a detailed market assessment of pelacarsen for myocardial infarction in the seven major markets, i.e., the United States, EU4 (Germany, France, Italy, and Spain) and the United Kingdom, and Japan. This segment of the report provides forecasted sales data from 2026 to 2032.Pelacarsen Clinical Assessment
The report provides the clinical trials information of pelacarsen for myocardial infarction covering trial interventions, trial conditions, trial status, start and completion dates.Report Highlights
- In the coming years, the market scenario for myocardial infarction is set to change due to the extensive research and incremental healthcare spending across the world; which would expand the size of the market to enable the drug manufacturers to penetrate more into the market.
- The companies are developing therapies that focus on novel approaches to treat/improve the disease condition, assess challenges, and seek opportunities that could influence pelacarsen dominance.
- Other emerging products for myocardial infarction are expected to give tough market competition to pelacarsen and launch of late-stage emerging therapies in the near future will significantly impact the market.
- A detailed description of regulatory milestones, and developmental activities, provide the current development scenario of pelacarsen in myocardial infarction.
- Our in-depth analysis of the forecasted sales data of pelacarsen from 2026 to 2032 will support the clients in the decision-making process regarding their therapeutic portfolio by identifying the overall scenario of the pelacarsen in myocardial infarction.
Key Questions Answered
- What is the product type, route of administration and mechanism of action of pelacarsen?
- What is the clinical trial status of the study related to pelacarsen in myocardial infarction and study completion date?
- What are the key collaborations, mergers and acquisitions, licensing and other activities related to the pelacarsen development?
- What are the key designations that have been granted to pelacarsen for myocardial infarction?
- What is the forecasted market scenario of pelacarsen for myocardial infarction?
- What are the forecasted sales of pelacarsen in the seven major countries, including the United States, Europe (Germany, France, Italy, Spain, and the United Kingdom), and Japan?
- What are the other emerging products available and how are these giving competition to pelacarsen for myocardial infarction?
- Which are the late-stage emerging therapies under development for the treatment of myocardial infarction?
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