Crohn's Disease Therapeutics Market Size and Forecast 2021 - 2031, Global and Regional Share, Trend, and Growth Opportunity Analysis Report Coverage: By Drug Class, Distribution Channel, and Geography

The Crohn’s disease therapeutics market is expected to grow from US$ 9.68 billion in 2023 to US$ 13.33 billion by 2031; it is anticipated to record a CAGR of 4.1% from 2023 to 2031.

Crohn's disease is a chronic inflammatory condition primarily affecting the gastrointestinal tract. It commonly affects the end part of the small intestine and the beginning of the large intestine. The disease is characterized by the inflammation of the digestive tract lining, leading to symptoms such as abdominal pain, diarrhea, and malnutrition. The growing Crohn's disease therapeutics market size is attributed to the increasing prevalence of diseases in Western countries, particularly the US. In addition, strategic initiatives by companies to stay competitive are fueling market growth. A significant increase in the use of medical devices is likely to bring new Crohn's disease therapeutics market trends during the forecast period.

Penetration of Precision Medicine for the Treatment of Crohn’s disease will Create an Opportunity for Crohn’s disease therapeutics market growth.

Precision medicine aims to modify the medical therapy to the individual characteristics of each patient, including environmental factors, genetic makeup, lifestyle, and other variables. In Crohn’s disease therapy, precision medicine holds significant assurance for improving the patient's results and minimizing the adverse effects. There are a few ways precision medicine is applied during Crohn’s disease therapy, like genetic profiling, biomarker identification, pharmacogenomics, targeted therapies, and predictive modeling & machine learning. In genetic profiling, genetic sequencing technologies allow the researcher to discover specific genetic variations associated with Crohn’s disease susceptibility and treatment response. This will help them choose the medicine that is likely to respond well and allow for a personalized medication plan.

Analyzing and examining the specific biomarkers associated with Crohn’s disease activity will help researchers better access disease severity and predict better outcomes. Targeted therapy is another method in precision medicine that selectively inhibits specific molecules responsible for the inflammatory process responsible for Crohn’s disease. Such personalized treatment enhanced efficiency and reduced systemic toxicity compared with conventional therapies.

Precision medicine further allowed the stratification method, which allowed the stratification of patients into distinct subgroups based on the prior diseases' characteristics, biomarkers, and various genetic signatures. Such treatment approaches can optimize the treatment response rate, minimize the treatment response rate, and improve long-term outcomes in the treatment of Crohn’s disease treatment.

Predictive modeling and machine learning techniques can analyze complex data sets to identify patterns and predict disease progression. This allows the integration of genetic, clinical, and other relevant data. Predictive modeling techniques can support the clinician in making informed treatment decisions and personalizing the therapy based on patient characteristics.

Precision therapy holds huge potential for the treatment of Crohn’s disease therapy by allowing individualized treatment approaches with diverse genetics, molecular factors, and contributing clinical factors. This treatment plays a prominent role in irritable bowel syndrome and optimizes patient outcomes in managing Crohn’s disease.

Precision medicine has significantly progressed in treating Crohn’s diseases, but many objectives are still unmet on the ground level. It requires a huge data bank, various algorithm tools like big data, Hadoop, and advanced infrastructure with which it can be implemented effectively. Implementing advanced analytics in precision medicine will create huge opportunities for treating Crohn’s disease therapeutics market.

Based on geography, the Crohn’s disease therapeutics market is segmented into North America (US, Canada, and Mexico), Europe (UK, Germany, France, Italy, Spain, Russia, and Rest of Europe), Asia Pacific (China, Japan, India, South Korea, Australia, Southeast Asia, and Rest of Asia Pacific), the Middle East & Africa (UAE, Saudi Arabia, South Africa, and Rest of Middle East & Africa), and South & Central America (Brazil, Argentina, and Rest of South & Central America). North America held the largest share of the global Crohn’s disease therapeutics market in 2023 owing to the lifestyle factor. However, Asia Pacific is predicted to register the highest CAGR during 2023-2031. The US held the largest share of the Crohn’s disease therapeutics market in North America in 2022. Market players in the US are adopting organic and inorganic strategies for Crohn’s disease therapeutics market development. For instance, in 2023, the US Food and Drug Administration (FDA) approved the first oral pill - Rinvoq (upadacitinib) - to treat moderate-to-severe Crohn's disease. Rinvoq is meant to treat adult patients who could not be treated successfully with drug candidates blocking tumor necrosis factor (TNF). Furthermore, in In 2021, AbbVie Inc. announced the initiation of the Phase 3 trial of risankizumab for the treatment of Crohn's disease. Risankizumab is a humanized monoclonal antibody that selectively targets the interleukin-23 (IL-23) pathway. The trial is aimed at evaluating the efficacy and safety of risankizumab in patients with moderate-to-severe Crohn's disease. Thus, the factors mentioned above support the market growth.