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Botanicals and Natural Bioactives: Prevention and Treatment of Diseases

  • Book

  • March 2024
  • Bentham Science Publishers Ltd
  • ID: 5960306
Briefs in Biomedicine and Pharmacotherapy showcases the latest developments and techniques in the fields of pharmacology and healthcare, presenting them in distinctive volumes. Each volume offers a concise, focused overview of subjects, authored by experts in the field. The book series serves as an anthology for graduate students and researchers in pharmacology and life sciences, as well as medical professionals seeking specialization for research-related projects.

The second volume, Botanicals and Natural Bioactives: Prevention and Treatment of Diseases, discusses the medicinal applications of natural bioactives in the treatment of a variety of physiological disorders, including cardiovascular diseases, neurological dysfunctions, infectious diseases, age-related diseases, and cancer. The volume has eight chapters on disease treatment and preventative measures, with contributions from more than twenty experts. Readers will comprehend the niche utilization of botanicals and natural bioactives as medicinal agents for a variety of ailments. Overall, the chapters dwell on the chemosensory features of nutritious foods to avoid non-communicable diseases and the role of immunomodulating natural products and botanicals in the prevention and treatment of skin diseases, aging, inflammation, cancer, parasitic infections in the bloodstream, neurodegenerative diseases, osteoporosis, coronary heart disease, and autoimmune disorders. The variety of topics covered in this book makes it an excellent resource for a wide audience interested in phytomedicine.

Readership

Students, researchers, pharmacologists, medicinal chemists, healthcare professionals and clinicians.

Table of Contents

CHAPTER 1 FOOD COLOR, TASTE, SMELL, CULINARY PLATE, FLAVOR, LOCALE,
  • AND THEIR IMPACT ON NUTRITION: PRESENT AND FUTURE MULTISENSORY FOOD
  • AUGMENTATION AND NON-COMMUNICABLE DISEASE PREVENTION: AN OVERVIEW 1
  • Douglas W. Wilson, Fabien De Meester, Toru Takahashi, Ram B. Singh and Harpal S.
  • Buttar
  • INTRODUCTION
  • Food
  • Color
  • Taste
  • Smell
  • Culinary Plate
  • Flavor
  • Locale
  • Impact on Nutrition and Non-communicable Disease Prevention
  • DISCUSSION
  • Global NCD: Future Research
  • Visual Cues
  • Olfaction
  • Texture
  • CONCLUSION
  • AUTHORSHIP ATTRIBUTION
  • ABBREVIATIONS
  • REFERENCES
CHAPTER 2 OXIDATIVE STRESS AND PROTEIN MISFOLDING IN SKIN AGING
  • Tushar Oak, Riya Patel and Maushmi S. Kumar
  • INTRODUCTION
  • Oxidative Stress - The Underlying Mechanism
  • Biomarkers Involved in Oxidative Stress
  • Glutathione
  • Polyphenols
  • Carotenoids
  • Dietary Minerals
  • Ascorbic Acid
  • Vitamin E
  • Ubiquinone
  • Organosulfur Compounds
  • PROTEIN MISFOLDING AND ITS MECHANISM
  • Chaperones
  • Skin Aging
  • Collagen
  • Increase in Matrix Metalloproteinase Levels (MMPs)
  • Impaired Transforming Growth Factor-β Signalling During Aging
  • Interaction Between Fibroblasts and the ECM
  • TREATMENT
  • Natural Products and Their Role in Anti-Aging
  • Aloe vera
  • Curcuma longa
  • Zingiber officinale
  • Citrus sinensis
  • Piper betel
  • Curculigo orchioides
  • Prunus dulcis
  • Labisia pumila
  • Aesculus hippocastanum
  • Significance of Caenorhabditis elegans
  • CONCLUSION
  • ABBREVIATIONS
  • ACKNOWLEDGEMENTS
  • REFERENCES
CHAPTER 3 THERAPEUTIC SCOPE AND APPLICATION OF MUSHROOM-DERIVED
  • PHARMACOACTIVES IN ENHANCING HEALTH
  • Sharika Rajasekharan Pillai and Siriporn Chuchawankul
  • INTRODUCTION
  • Mushrooms as a Valuable Source of Nutrition and Nutraceuticals
  • Polysaccharides
  • Proteins
  • Lectins
  • Fungal Immunomodulatory Protein (FIPs)
  • Ribosome Inactivating Proteins (RIPs)
  • Laccases
  • Bioactive Peptides
  • Terpenes and Terpenoids
  • Cordycepin
  • Ergosterol
  • THERAPEUTIC SCOPE OF MUSHROOM-DERIVED BIOACTIVES
  • Immunomodulatory and Anti-inflammatory Activity
  • Anti-cancer Activity
  • Antioxidant Activity
  • CONCLUSION
  • ABBREVIATIONS
  • ACKNOWLEDGEMENTS
  • REFERENCES
CHAPTER 4 NATURAL PRODUCTS AS ANTIOXIDANT ADJUNCT THERAPY FOR
  • BLOOD PARASITIC INFECTIONS
  • Paweena Pradniwat
  • INTRODUCTION
  • OXIDATIVE STRESS IN BLOOD PARASITE INFECTIONS
  • Malarial Infection
  • Plasmodium-Induced Oxidative Stress in the Host
  • Hemoglobin Degradation Induces Oxidative Stress
  • Host’s Xanthine Oxidase Induces Oxidative Stress
  • Phagocytic Oxidative Burst from Host Defense Mechanism
  • Antimalarial Drugs
  • Anti-malarial Drugs Interfering with Oxidative Stress
  • Babesia spp. Infection
  • Trypanosoma spp. Infection
  • Leishmania spp. Infection
  • NATURAL PRODUCTS FOR BLOOD PROTOZOA TREATMENTS
  • Achillea millefolium Aerial Part Decoction and Essential Oil
  • Clerodendrum violaceum Leaf Methanolic Extract
  • Acanthus polystachyus Leaf Hydro-methanolic Extract
  • Lippia multiflora Leaf Extract and Lippia sidoides Essential Oils
  • Moringa oleifera Lam Extract
  • Erythrina burttii Acetone Root-bark Extract
  • Indigofera oblongifolia Leaf Extract
  • Argania spinosa Fruit Ethyl Acetate Extract, and Decoction
  • Gardenia ternifolia
  • Ziziphus mauritiana
  • Anthocleista djalonensis
  • CONCLUSION
  • ABBREVIATIONS
  • REFERENCES
CHAPTER 5 NATURAL PRODUCTS AS A THERAPEUTIC APPROACH IN REGULATING
  • AUTOPHAGY FOR THE MANAGEMENT OF NEURODEGENERATIVE DISEASES
  • Mani Iyer Prasanth, Dicson Sheeja Malar and Tewin Tencomnao
  • INTRODUCTION
  • AUTOPHAGY IN NEURODEGENERATIVE DISEASES
  • AUTOPHAGY, NEUROPROTECTION, AND PHYTOMEDICINES
  • MODULATION OF AUTOPHAGY BY PLANT EXTRACTS/ COMPOUNDS TO
  • AMELIORATE NEUROLOGICAL DYSFUNCTION
  • Herbal Teas’ and Their Constituents
  • Vitis vinifera and Its Constituent Resveratrol
  • Ginkgo biloba and Its Constituents
  • Panax ginseng and Its Constituents
  • CONCLUSION
  • ABBREVIATIONS
  • ACKNOWLEDGEMENTS
  • REFERENCES
CHAPTER 6 PROPITIOUS EFFECTS OF NATURAL BIOACTIVES FOR OSTEOPOROSIS:
  • SPECIAL EMPHASIS FROM MARINE SOURCE
  • Shravya Shanbhag, Palak Parekh and Maushmi S. Kumar
  • INTRODUCTION
  • OSTEOPOROSIS- PATHOGENESIS AND MORPHOLOGIC FEATURES
  • TREATMENT FOR OSTEOPOROSIS
  • Bisphosphonates
  • Denosumab Injections
  • Selective Estrogen Receptor Modulator (SERM) Therapy
  • Antiosteoporotic Bioactives Extracted from Plants and Animals
  • MARINE NATURAL PRODUCTS (MNPS)
  • Sponges
  • Cyanobacteria
  • Fungi
  • Dinoflagellates
  • Algae
  • Mangroves
  • Soft Corals
  • Molluscs
  • Fishes
  • FUTURE SCOPE OF MARINE BIOACTIVE FOR TREATMENT OF OSTEOPOROSIS 139
  • Osteoporosis - Result of Novel Coronavirus
  • CONCLUSION
  • ABBREVIATIONS
  • ACKNOWLEDGEMENTS
  • REFERENCES
CHAPTER 7 PATHOGENESIS OF ATHEROSCLEROSIS AND CORONARY HEART
  • DISEASE: EPIDEMIOLOGY, DIAGNOSTIC BIOMARKERS AND PREVENTION BY
  • NUTRACEUTICALS, FUNCTIONAL FOODS, AND PLANT-DERIVED THERAPIES
  • Prabhnain Kaur, Ritu Dahiya, Ginpreet Kaur, Harpal S. Buttar, Douglas W.
  • Wilson and Istvan G. Telessy
  • INTRODUCTION
  • PATHOGENESIS OF ATHEROSCLEROSIS
  • Epidemiology
  • Diagnostic Biomarkers
  • C Reactive Protein (CRP)
  • Interleukin-6 (IL-6)
  • Interleukin-18 (IL-18)
  • Cardiac Troponin
  • Brain Natriuretic Peptide (BNP)
  • Cystatin C
  • Lipoprotein-Associated Phospholipase A2 (Lp-PLA2)
  • MicroRNAs
  • Osteocalcin (OC)
  • Angiogenin (ANG)
  • Monocyte Chemoattractant Protein-1 (MCP-1)
  • Placental Growth Factor (PLGF)
  • Pregnancy-Associated Plasma Protein-A (PAPP-A)
  • Soluble CD40 Ligand (CD40L)
  • COST-EFFECTIVE STRATEGIES TO PREVENT ATHEROSCLEROSIS AND
  • CARDIOVASCULAR DISEASES
  • Berries: Rubus (Family: Rosaceae)
  • Beans: Phaseolus vulgaris (Family: Fabaceae)
  • Sea Food
  • Tomatoes and tomato products (Family: Solanaceae)
  • Onions (Allium sativum, A. cepa - Family: Amaryllidaceae)
  • Citrus Fruits
  • Culinary Spices
  • Flaxseeds (Family: Linaceae)
  • Beetroot (Beta vulgaris)- Family: Chenopodiaceae
  • Whole grains (Families: Poaceae and Gramineae)
  • Oats (Poaceae Grass, Avena sativa)
  • Cocoa and Dark Chocolate
  • Olive Oil (Family: Oleaceae)
  • Nuts and Seeds

Author

  • Pardeep Kaur
  • Tewin Tencomnao
  • Robin
  • Rajendra G. Mehta