The global tissue sealants market accounted for USD 2.45 billion in 2023 and is expected to reach at USD 5.11 billion by 2034 with a CAGR of 6.92% during the forecast period 2024-2034. Increase in the frequency of surgical procedures, rise in sports-related injuries & accidents, growing demand for minimally invasive surgeries, surge in the prevalence of joint & bone disorders, increasing advancements in cartilage repair & regeneration technologies, rising aging population, high demand for knee replacement surgeries, growing collaborations among key market players & research institutions for the development of tissue sealants, surge in number of product approvals, and rising introduction of innovative tissue sealant devices are some of the key factors boosting the market growth.
Rising introduction of innovative tissue sealant devices is predicted to boost the market growth during the forecast period. Tissue sealants are utilized to seal and close tissue injuries or defects, primarily by enhancing the coagulation process. They find extensive application in minimally invasive surgical techniques and contribute to decreasing mortality rates resulting from traumatic injuries. Moreover, they are commonly employed in treating stomach ulcers, managing blood loss during childbirth surgeries, and addressing blood vessel ruptures. For instance, in November 2023, Pramand LLC has officially introduced the CraniSeal Dural Sealant System for commercial use in the United States. CraniSeal is designed to be utilized in patients aged 18 years and above as an additional aid in achieving watertight closure during cranial surgery, particularly alongside sutured dural repair.
By product, natural was the highest revenue-grossing segment in the global tissue sealants market in 2023 owing to the increase in the prevalence of cardiac & orthopedic surgeries, rising advancements in technology, surge in product approvals, and growing emphasis from manufacturers & industry players on the development of innovative products. For instance, in January 2023, Grifols, a significant player in plasma medicine, announced favorable top-line findings from a phase 3b clinical trial of its fibrin sealant (FS) for addressing surgical bleeding in pediatric patients. Additionally, synthetic is predicted to grow at the fastest CAGR during the forecast period owing to the robust mechanical strength & simple adhesion process, rising demand for cyanoacrylates because of their rapid drying rate, and increase in partnerships and acquisitions by major industry players.
By application, general surgery was the highest revenue-grossing segment in the global tissue sealants market in 2023 owing to the rise in the number of general surgical procedures, increase in the occurrence of hernia cases, and growing number of regulatory approvals. For instance, in June 2023, The U.S. Food and Drug Administration (FDA) has granted Pre-Market Approval (PMA) for LiquiBandFix8, a device containing a Cyanoacrylate adhesive, which is approved for use in hernia surgery. Additionally, cosmetic is predicted to grow at the fastest CAGR during the forecast period owing to the growing prevalence of cosmetic procedures, and a wide array of surgical sealants and adhesives available for use in cosmetic surgeries.
By end-user, hospital was the highest revenue-grossing segment in the global tissue sealants market in 2023 owing to the increase in the number of surgeries performed, growing elderly population, surge in the prevalence of various diseases, and increasing introduction of new medical products. For instance, in November 2023, Johnson & Johnson's MedTech division, Ethicon, introduced Ethizia, a hemostatic sealing patch designed to manage bleeding during surgical procedures. Additionally, specialty clinics & trauma centers is predicted to grow at the fastest CAGR during the forecast period owing to the increase in the incidence of accidents and sports-related injuries, leading to a heightened necessity to manage blood loss in trauma cases, injuries, or surgical interventions.
North America region is anticipated for the highest revenue share during the forecast period owing to the uptick in bone & sports-related injuries, rise in surgical procedures, expanding geriatric population, growing investments in the healthcare sector, rapid technological adoption, and increase in product launches. For instance, in March 2023, Animus Surgical has introduced Membra, a novel transparent hydrogel wound sealant that is non-toxic and biodegradable, aiming to serve as an alternative to traditional bandages. Additionally, Asia Pacific region is predicted to grow at fastest CAGR during the forecast period owing to the rise in public awareness about healthcare, increase in government initiatives towards the healthcare sector, growing number of research endeavors, increase in the occurrence of hip & knee replacement surgeries, and surge in the introduction of innovative medical devices. For instance, in April 2022, Ethicon, a provider of surgical solutions, introduced the ENSEAL X1 Straight Jaw Tissue Sealer designed to offer enhanced sealing strength, improved efficiency, and simplified access to specific tissue areas in various surgical procedures.
This comprehensive research report focuses on the global and regional market size and forecasts from 2023 to 2034.
Rising introduction of innovative tissue sealant devices is predicted to boost the market growth during the forecast period. Tissue sealants are utilized to seal and close tissue injuries or defects, primarily by enhancing the coagulation process. They find extensive application in minimally invasive surgical techniques and contribute to decreasing mortality rates resulting from traumatic injuries. Moreover, they are commonly employed in treating stomach ulcers, managing blood loss during childbirth surgeries, and addressing blood vessel ruptures. For instance, in November 2023, Pramand LLC has officially introduced the CraniSeal Dural Sealant System for commercial use in the United States. CraniSeal is designed to be utilized in patients aged 18 years and above as an additional aid in achieving watertight closure during cranial surgery, particularly alongside sutured dural repair.
By product, natural was the highest revenue-grossing segment in the global tissue sealants market in 2023 owing to the increase in the prevalence of cardiac & orthopedic surgeries, rising advancements in technology, surge in product approvals, and growing emphasis from manufacturers & industry players on the development of innovative products. For instance, in January 2023, Grifols, a significant player in plasma medicine, announced favorable top-line findings from a phase 3b clinical trial of its fibrin sealant (FS) for addressing surgical bleeding in pediatric patients. Additionally, synthetic is predicted to grow at the fastest CAGR during the forecast period owing to the robust mechanical strength & simple adhesion process, rising demand for cyanoacrylates because of their rapid drying rate, and increase in partnerships and acquisitions by major industry players.
By application, general surgery was the highest revenue-grossing segment in the global tissue sealants market in 2023 owing to the rise in the number of general surgical procedures, increase in the occurrence of hernia cases, and growing number of regulatory approvals. For instance, in June 2023, The U.S. Food and Drug Administration (FDA) has granted Pre-Market Approval (PMA) for LiquiBandFix8, a device containing a Cyanoacrylate adhesive, which is approved for use in hernia surgery. Additionally, cosmetic is predicted to grow at the fastest CAGR during the forecast period owing to the growing prevalence of cosmetic procedures, and a wide array of surgical sealants and adhesives available for use in cosmetic surgeries.
By end-user, hospital was the highest revenue-grossing segment in the global tissue sealants market in 2023 owing to the increase in the number of surgeries performed, growing elderly population, surge in the prevalence of various diseases, and increasing introduction of new medical products. For instance, in November 2023, Johnson & Johnson's MedTech division, Ethicon, introduced Ethizia, a hemostatic sealing patch designed to manage bleeding during surgical procedures. Additionally, specialty clinics & trauma centers is predicted to grow at the fastest CAGR during the forecast period owing to the increase in the incidence of accidents and sports-related injuries, leading to a heightened necessity to manage blood loss in trauma cases, injuries, or surgical interventions.
North America region is anticipated for the highest revenue share during the forecast period owing to the uptick in bone & sports-related injuries, rise in surgical procedures, expanding geriatric population, growing investments in the healthcare sector, rapid technological adoption, and increase in product launches. For instance, in March 2023, Animus Surgical has introduced Membra, a novel transparent hydrogel wound sealant that is non-toxic and biodegradable, aiming to serve as an alternative to traditional bandages. Additionally, Asia Pacific region is predicted to grow at fastest CAGR during the forecast period owing to the rise in public awareness about healthcare, increase in government initiatives towards the healthcare sector, growing number of research endeavors, increase in the occurrence of hip & knee replacement surgeries, and surge in the introduction of innovative medical devices. For instance, in April 2022, Ethicon, a provider of surgical solutions, introduced the ENSEAL X1 Straight Jaw Tissue Sealer designed to offer enhanced sealing strength, improved efficiency, and simplified access to specific tissue areas in various surgical procedures.
This comprehensive research report focuses on the global and regional market size and forecasts from 2023 to 2034.
Report Scope:
- Base Year: 2023
- Forecast Period: 2024-2034
- Study Coverage
- Market Forecast by Product, Application, and End-user
- Market Forecast for 5 Regions and 17+ Countries
- North America (U.S. and Canada)
- Europe (Germany, France, UK, Spain, Italy, Russia, Rest of Europe)
- Asia Pacific (China, Japan, India, Australia, South Korea, Rest of APAC)
- Latin America (Brazil, Mexico, Argentina, Rest of LATAM)
- MEA (South Africa, GCC, Rest of MEA)
- Exhaustive Company Profiles of Top 10+ Major Market Players
Segmentation: Tissue Sealants Market Report 2023 - 2034
Tissue Sealants Market Analysis & Forecast by Product 2023 - 2034 (Revenue USD Bn)
- Natural
- Fibrin Sealant
- Gelatin-based Adhesives
- Collagen-based Adhesive
- Synthetic
- Polyethylene Glycol Polymer
- Polymeric Hydrogels
- Cyanoacrylates
- Other
Tissue Sealants Market Analysis & Forecast by Application 2023 - 2034 (Revenue USD Bn)
- Orthopaedic
- Pulmonary
- Neurology
- Colorectal
- Urology
- Cosmetic
- Cardiovascular
- Ophthalmology
- General Surgery
- Others
Tissue Sealants Market Analysis & Forecast by End-user 2023 - 2034 (Revenue USD Bn)
- Specialty Clinics & Trauma Centers
- Hospitals
- Ambulatory Surgical Centers
- Research & Academic Institutes
- Others
Tissue Sealants Market Analysis & Forecast by Region 2023 - 2034 (Revenue USD Bn)
- North America
- U.S.
- Canada
- Europe
- Germany
- France
- UK
- Spain
- Italy
- Rest of Europe
- Asia Pacific
- China
- Japan
- India
- Australia
- South Korea
- Rest of APAC
- Latin America
- Brazil
- Mexico
- Argentina
- Rest of LATAM
- Middle East & Africa
- South Africa
- GCC
- Rest of MEA
Table of Contents
1. Research Methodology
2. Introduction
4. Market Environment Analysis
5. Market Dynamics
7. Tissue Sealants Market: Product Estimates & Trend Analysis
8. Tissue Sealants Market: Application Estimates & Trend Analysis
9. Tissue Sealants Market: End-user Estimates & Trend Analysis
10. Regional Market Analysis
11. North America Tissue Sealants Market
12. Europe Global Tissue Sealants Market
13. Asia Pacific Global Tissue Sealants Market
14. Latin America Global Tissue Sealants Market
15. MEA Global Tissue Sealants Market
16. Competitor Analysis
17. Company Profiles
Companies Mentioned
- Baxter
- Cohera Medical
- Integra Lifesciences
- Becton
- Dickinson and Company
- B. Braun SE
- Johnson and Johnson (Ethicon Inc.)
- Avin Darou
- Grünenthal (Adhesys Medical Inc)
- CSL Behring
- CryoLife Inc.
