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Liver Fibrosis Market: Epidemiology, Industry Trends, Share, Size, Growth, Opportunity, and Forecast 2024-2034

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    Report

  • 132 Pages
  • May 2024
  • Region: Global
  • IMARC Group
  • ID: 5969744
The 7 major liver fibrosis markets reached a value of US$ 2.3 Billion in 2023. Looking forward, the publisher expects the 7MM to reach US$ 5.1 Billion by 2034, exhibiting a growth rate (CAGR) of 9.25% during 2023-2034.

The liver fibrosis market has been comprehensively analyzed in this report titled "Liver Fibrosis Market: Epidemiology, Industry Trends, Share, Size, Growth, Opportunity, and Forecast 2024-2034". Liver fibrosis is a process of excessive scarring or fibrous tissue formation in the liver in response to injury or damage. Over time, the accumulation of scar cells can result in the liver becoming stiff and unable to function normally. Individuals suffering from this condition may initially experience decreased appetite, difficulty thinking clearly, accumulation of fluid in the legs or stomach, shortness of breath, nausea, unexplained weight loss, muscle weakness, etc. During later stages, the disease manifests as the appearance of yellowish color in the skin and eyes, confusion, abdominal swelling, reduced hormone production, bruising, dark urine, gastrointestinal bleeding, etc. The diagnosis of this ailment requires a combination of the patient's detailed medical history, underlying indications, and various blood tests. The healthcare provider may also perform several diagnostic procedures, like ultrasonography, computed tomography, magnetic resonance imaging, etc., to detect changes in the hepatic parenchyma associated with the moderate-to-severe disease condition. Liver biopsy and histologic examination are further recommended for the assessment of neuroinflammatory grades and stages of fibrosis in patients.

The increasing prevalence of injury and inflammation in the liver, which causes excessive buildup of proteins, such as collagen and glycoproteins, between the hepatic cells, is primarily driving the liver fibrosis market. In addition to this, the rising incidences of several associated risk factors, including excessive alcohol consumption, obesity, autoimmune hepatitis, destruction of the bile ducts, etc., are also bolstering the market growth. Furthermore, the escalating adoption of antifibrotic drugs, such as belapectin, cenicriviroc, liraglutide, etc., to help decrease the likelihood of permanent liver scarring in patients is acting as another significant growth-inducing factor. Additionally, the emerging popularity of next-generation plasma protein profiling, which aids in identifying potential biomarkers of liver fibrosis and understanding the disease mechanisms that can guide personalized treatment strategies, is also creating a positive outlook for the market. Moreover, the widespread demand for cell therapy for the treatment of this illness, since it can repair or replace damaged cells in the liver and enhance the production of hepatic enzymes, thereby improving the quality of life in patients, is expected to drive the liver fibrosis market in the coming years.

This report provides an exhaustive analysis of the liver fibrosis market in the United States, EU5 (Germany, Spain, Italy, France, and United Kingdom) and Japan. This includes treatment practices, in-market, and pipeline drugs, share of individual therapies, market performance across the seven major markets, market performance of key companies and their drugs, etc. The report also provides the current and future patient pool across the seven major markets. According to the report the United States has the largest patient pool for liver fibrosis and also represents the largest market for its treatment. Furthermore, the current treatment practice/algorithm, market drivers, challenges, opportunities, reimbursement scenario and unmet medical needs, etc. have also been provided in the report. This report is a must-read for manufacturers, investors, business strategists, researchers, consultants, and all those who have any kind of stake or are planning to foray into the liver fibrosis market in any manner.

Time Period of the Study

  • Base Year: 2023
  • Historical Period: 2018-2023
  • Market Forecast: 2024-2034

Countries Covered

  • United States
  • Germany
  • France
  • United Kingdom
  • Italy
  • Spain
  • Japan

Analysis Covered Across Each Country

  • Historical, current, and future epidemiology scenario
  • Historical, current, and future performance of the liver fibrosis market
  • Historical, current, and future performance of various therapeutic categories in the market
  • Sales of various drugs across the liver fibrosis market

Competitive Landscape:

This report also provides a detailed analysis of the current liver fibrosis marketed drugs and late-stage pipeline drugs.

In-Market Drugs

  • Drug Overview
  • Mechanism of Action
  • Regulatory Status
  • Clinical Trial Results
  • Drug Uptake and Market Performance

Late-Stage Pipeline Drugs

  • Drug Overview
  • Mechanism of Action
  • Regulatory Status
  • Clinical Trial Results
  • Drug Uptake and Market Performance
*Kindly note that the drugs in the above table only represent a partial list of marketed/pipeline drugs, and the complete list has been provided in the report.

Key Questions Answered in this Report:

Market Insights

  • How has the liver fibrosis market performed so far and how will it perform in the coming years?
  • What are the markets shares of various therapeutic segments in 2023 and how are they expected to perform till 2034?
  • What was the country-wise size of the liver fibrosis market across the seven major markets in 2023 and what will it look like in 2034?
  • What is the growth rate of the liver fibrosis market across the seven major markets and what will be the expected growth over the next ten years?
  • What are the key unmet needs in the market?

Epidemiology Insights

  • What is the number of prevalent cases (2018-2034) of liver fibrosis across the seven major markets?
  • What is the number of prevalent cases (2018-2034) of liver fibrosis by age across the seven major markets?
  • What is the number of prevalent cases (2018-2034) of liver fibrosis by gender across the seven major markets?
  • How many patients are diagnosed (2018-2034) with liver fibrosis across the seven major markets?
  • What is the size of the liver fibrosis patient pool (2018-2023) across the seven major markets?
  • What would be the forecasted patient pool (2024-2034) across the seven major markets?
  • What are the key factors driving the epidemiological trend of liver fibrosis?
  • What will be the growth rate of patients across the seven major markets?

Liver Fibrosis: Current Treatment Scenario, Marketed Drugs and Emerging Therapies

  • What are the current marketed drugs and what are their market performance?
  • What are the key pipeline drugs and how are they expected to perform in the coming years?
  • How safe are the current marketed drugs and what are their efficacies?
  • How safe are the late-stage pipeline drugs and what are their efficacies?
  • What are the current treatment guidelines for liver fibrosis drugs across the seven major markets?
  • Who are the key companies in the market and what are their market shares?
  • What are the key mergers and acquisitions, licensing activities, collaborations, etc. related to the liver fibrosis market?
  • What are the key regulatory events related to the liver fibrosis market?
  • What is the structure of clinical trial landscape by status related to the liver fibrosis market?
  • What is the structure of clinical trial landscape by phase related to the liver fibrosis market?
  • What is the structure of clinical trial landscape by route of administration related to the liver fibrosis market?
This product will be updated with the latest data at the time of order. Consequently, dispatch time for this product will be 7-10 business days.

Table of Contents

?1 Preface
2 Scope and Methodology
2.1 Objectives of the Study
2.2 Stakeholders
2.3 Data Sources
2.3.1 Primary Sources
2.3.2 Secondary Sources
2.4 Market Estimation
2.4.1 Bottom-Up Approach
2.4.2 Top-Down Approach
2.5 Forecasting Methodology
3 Executive Summary
4 Liver Fibrosis - Introduction
4.1 Overview
4.2 Regulatory Process
4.3 Epidemiology (2018-2023) and Forecast (2024-2034)
4.4 Market Overview (2018-2023) and Forecast (2024-2034)
4.5 Competitive Intelligence
5 Liver Fibrosis - Disease Overview
5.1 Introduction
5.2 Symptoms and Diagnosis
5.3 Pathophysiology
5.4 Causes and Risk Factors
5.5 Treatment
6 Patient Journey
7 Liver Fibrosis - Epidemiology and Patient Population
7.1 Epidemiology - Key Insights
7.2 Epidemiology Scenario - Top 7 Markets
7.2.1 Epidemiology Scenario (2018-2023)
7.2.2 Epidemiology Forecast (2024-2034)
7.2.3 Epidemiology by Age (2018-2034)
7.2.4 Epidemiology by Gender (2018-2034)
7.2.5 Diagnosed Cases (2018-2034)
7.2.6 Patient Pool/Treated Cases (2018-2034)
7.3 Epidemiology Scenario - United States
7.3.1 Epidemiology Scenario (2018-2023)
7.3.2 Epidemiology Forecast (2024-2034)
7.3.3 Epidemiology by Age (2018-2034)
7.3.4 Epidemiology by Gender (2018-2034)
7.3.5 Diagnosed Cases (2018-2034)
7.3.6 Patient Pool/Treated Cases (2018-2034)
7.4 Epidemiology Scenario - Germany
7.4.1 Epidemiology Scenario (2018-2023)
7.4.2 Epidemiology Forecast (2024-2034)
7.4.3 Epidemiology by Age (2018-2034)
7.4.4 Epidemiology by Gender (2018-2034)
7.4.5 Diagnosed Cases (2018-2034)
7.4.6 Patient Pool/Treated Cases (2018-2034)
7.5 Epidemiology Scenario - France
7.5.1 Epidemiology Scenario (2018-2023)
7.5.2 Epidemiology Forecast (2024-2034)
7.5.3 Epidemiology by Age (2018-2034)
7.5.4 Epidemiology by Gender (2018-2034)
7.5.5 Diagnosed Cases (2018-2034)
7.5.6 Patient Pool/Treated Cases (2018-2034)
7.6 Epidemiology Scenario - United Kingdom
7.6.1 Epidemiology Scenario (2018-2023)
7.6.2 Epidemiology Forecast (2024-2034)
7.6.3 Epidemiology by Age (2018-2034)
7.6.4 Epidemiology by Gender (2018-2034)
7.6.5 Diagnosed Cases (2018-2034)
7.6.6 Patient Pool/Treated Cases (2018-2034)
7.7 Epidemiology Scenario - Italy
7.7.1 Epidemiology Scenario (2018-2023)
7.7.2 Epidemiology Forecast (2024-2034)
7.7.3 Epidemiology by Age (2018-2034)
7.7.4 Epidemiology by Gender (2018-2034)
7.7.5 Diagnosed Cases (2018-2034)
7.7.6 Patient Pool/Treated Cases (2018-2034)
7.8 Epidemiology Scenario - Spain
7.8.1 Epidemiology Scenario (2018-2023)
7.8.2 Epidemiology Forecast (2024-2034)
7.8.3 Epidemiology by Age (2018-2034)
7.8.4 Epidemiology by Gender (2018-2034)
7.8.5 Diagnosed Cases (2018-2034)
7.8.6 Patient Pool/Treated Cases (2018-2034)
7.9 Epidemiology Scenario - Japan
7.9.1 Epidemiology Scenario (2018-2023)
7.9.2 Epidemiology Forecast (2024-2034)
7.9.3 Epidemiology by Age (2018-2034)
7.9.4 Epidemiology by Gender (2018-2034)
7.9.5 Diagnosed Cases (2018-2034)
7.9.6 Patient Pool/Treated Cases (2018-2034)
8 Liver Fibrosis - Treatment Algorithm, Guidelines, and Medical Practices
8.1 Guidelines, Management and Treatment
8.2 Treatment Algorithm
9 Liver Fibrosis - Unmet Needs10 Liver Fibrosis - Key Endpoints of Treatment
11 Liver Fibrosis - Marketed Products
11.1 List of Liver Fibrosis Marketed Drugs Across the Top 7 Markets
11.1.1 Drug Name - Company Name
11.1.1.1 Drug Overview
11.1.1.2 Mechanism of Action
11.1.1.3 Regulatory Status
11.1.1.4 Clinical Trial Results
11.1.1.5 Sales Across Major Markets
Kindly note that the complete list of marketed drugs has been provided in the report.
12 Liver Fibrosis - Pipeline Drugs
12.1 List of Liver Fibrosis Pipeline Drugs Across the Top 7 Markets
12.1.1 Nitazoxanide - Genfit
12.1.1.1 Drug Overview
12.1.1.2 Mechanism of Action
12.1.1.3 Clinical Trial Results
12.1.1.4 Safety and Efficacy
12.1.1.5 Regulatory Status
12.1.2 PLN 1474 - Pliant Therapeutics
12.1.2.1 Drug Overview
12.1.2.2 Mechanism of Action
12.1.2.3 Clinical Trial Results
12.1.2.4 Safety and Efficacy
12.1.2.5 Regulatory Status
12.1.3 ALE.F02 - Alentis Therapeutics
12.1.3.1 Drug Overview
12.1.3.2 Mechanism of Action
12.1.3.3 Clinical Trial Results
12.1.3.4 Safety and Efficacy
12.1.3.5 Regulatory Status
Kindly note that the above only represents a partial list of pipeline drugs, and the complete list has been provided in the report.
13. Liver Fibrosis - Attribute Analysis of Key Marketed and Pipeline Drugs
14. Liver Fibrosis - Clinical Trial Landscape
14.1 Drugs by Status
14.2 Drugs by Phase
14.3 Drugs by Route of Administration
14.4 Key Regulatory Events
15 Liver Fibrosis - Market Scenario
15.1 Market Scenario - Key Insights
15.2 Market Scenario - Top 7 Markets
15.2.1 Liver Fibrosis - Market Size
15.2.1.1 Market Size (2018-2023)
15.2.1.2 Market Forecast (2024-2034)
15.2.2 Liver Fibrosis - Market Size by Therapies
15.2.2.1 Market Size by Therapies (2018-2023)
15.2.2.2 Market Forecast by Therapies (2024-2034)
15.3 Market Scenario - United States
15.3.1 Liver Fibrosis - Market Size
15.3.1.1 Market Size (2018-2023)
15.3.1.2 Market Forecast (2024-2034)
15.3.2 Liver Fibrosis - Market Size by Therapies
15.3.2.1 Market Size by Therapies (2018-2023)
15.3.2.2 Market Forecast by Therapies (2024-2034)
15.3.3 Liver Fibrosis - Access and Reimbursement Overview
15.4 Market Scenario - Germany
15.4.1 Liver Fibrosis - Market Size
15.4.1.1 Market Size (2018-2023)
15.4.1.2 Market Forecast (2024-2034)
15.4.2 Liver Fibrosis - Market Size by Therapies
15.4.2.1 Market Size by Therapies (2018-2023)
15.4.2.2 Market Forecast by Therapies (2024-2034)
15.4.3 Liver Fibrosis - Access and Reimbursement Overview
15.5 Market Scenario - France
15.5.1 Liver Fibrosis - Market Size
15.5.1.1 Market Size (2018-2023)
15.5.1.2 Market Forecast (2024-2034)
15.5.2 Liver Fibrosis - Market Size by Therapies
15.5.2.1 Market Size by Therapies (2018-2023)
15.5.2.2 Market Forecast by Therapies (2024-2034)
15.5.3 Liver Fibrosis - Access and Reimbursement Overview
15.6 Market Scenario - United Kingdom
15.6.1 Liver Fibrosis - Market Size
15.6.1.1 Market Size (2018-2023)
15.6.1.2 Market Forecast (2024-2034)
15.6.2 Liver Fibrosis - Market Size by Therapies
15.6.2.1 Market Size by Therapies (2018-2023)
15.6.2.2 Market Forecast by Therapies (2024-2034)
15.6.3 Liver Fibrosis - Access and Reimbursement Overview
15.7 Market Scenario - Italy
15.7.1 Liver Fibrosis - Market Size
15.7.1.1 Market Size (2018-2023)
15.7.1.2 Market Forecast (2024-2034)
15.7.2 Liver Fibrosis - Market Size by Therapies
15.7.2.1 Market Size by Therapies (2018-2023)
15.7.2.2 Market Forecast by Therapies (2024-2034)
15.7.3 Liver Fibrosis - Access and Reimbursement Overview
15.8 Market Scenario - Spain
15.8.1 Liver Fibrosis - Market Size
15.8.1.1 Market Size (2018-2023)
15.8.1.2 Market Forecast (2024-2034)
15.8.2 Liver Fibrosis - Market Size by Therapies
15.8.2.1 Market Size by Therapies (2018-2023)
15.8.2.2 Market Forecast by Therapies (2024-2034)
15.8.3 Liver Fibrosis - Access and Reimbursement Overview
15.9 Market Scenario - Japan
15.9.1 Liver Fibrosis - Market Size
15.9.1.1 Market Size (2018-2023)
15.9.1.2 Market Forecast (2024-2034)
15.9.2 Liver Fibrosis - Market Size by Therapies
15.9.2.1 Market Size by Therapies (2018-2023)
15.9.2.2 Market Forecast by Therapies (2024-2034)
15.9.3 Liver Fibrosis - Access and Reimbursement Overview
16 Liver Fibrosis - Recent Events and Inputs From Key Opinion Leaders
17 Liver Fibrosis Market - SWOT Analysis
17.1 Strengths
17.2 Weaknesses
17.3 Opportunities
17.4 Threats
18 Liver Fibrosis Market - Strategic Recommendations19 Appendix

Methodology

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Table Information