+353-1-416-8900REST OF WORLD
+44-20-3973-8888REST OF WORLD
1-917-300-0470EAST COAST U.S
1-800-526-8630U.S. (TOLL FREE)
New

Protein Expression Market - Global Industry Size, Share, Trends, Opportunity, and Forecast, 2020-2030F

  • PDF Icon

    Report

  • 185 Pages
  • November 2025
  • Region: Global
  • TechSci Research
  • ID: 5978888
Free Webex Call
10% Free customization

Prokaryotic is the fastest growing segment, North America is the largest regional market

Free Webex Call

Speak directly to the analyst to clarify any post sales queries you may have.

10% Free customization

This report comes with 10% free customization, enabling you to add data that meets your specific business needs.

The Global Protein Expression Market will grow from USD 3.90 Billion in 2024 to USD 6.83 Billion by 2030 at a 9.80% CAGR. Protein expression describes the complex biological mechanisms by which genetic instructions are converted into functional proteins within living cells, constituting an essential methodology for biological research, drug discovery, and biopharmaceutical manufacturing. The market's growth is primarily fueled by the increasing global demand for recombinant proteins for therapeutic applications, including the development of advanced vaccines and monoclonal antibodies.

Key Market Drivers

The global protein expression market is significantly influenced by the increasing demand for biologics and protein therapeutics, which directly drives the need for sophisticated protein production capabilities. Biologics, encompassing monoclonal antibodies, advanced vaccines, and gene therapies, offer highly specific and effective treatment options for a broad spectrum of complex diseases. The consistent expansion in the development and manufacturing of these therapeutics mandates efficient and scalable protein expression systems. According to DCAT Value Chain Insights, in 2024, the FDA's Center for Drug Evaluation and Research approved 16 biological therapeutics, representing 32% of new drug approvals, highlighting the sustained output from this critical sector.

Key Market Challenges

The substantial costs associated with advanced expression systems and specialized reagents present a significant impediment to the growth of the global protein expression market. The financial outlay required for procuring, maintaining, and operating these sophisticated technologies, along with the recurring expense of highly specific reagents, creates a notable barrier to entry. This directly constrains smaller research institutions, emerging biotechnology companies, and academic laboratories from fully leveraging protein expression capabilities due to budget limitations, thereby impeding wider adoption across diverse research and industrial settings.

Key Market Trends

Integration of Artificial Intelligence and Machine Learning for Expression Optimization significantly influences the global protein expression market by offering enhanced efficiency and predictive capabilities. These advanced computational methods enable researchers to precisely predict optimal protein expression conditions and design more effective protein constructs, accelerating drug candidate identification. According to a November 2024 report by the Information Technology and Innovation Foundation, AI has the potential to transform drug development, potentially reducing timelines by approximately half. This technological shift facilitates faster cycles and improved success rates in producing complex proteins. For instance, a September 2024 news release from the University of Texas at Austin detailed their team receiving nearly $2.5 million in grant funding for applying AI in protein engineering research for vaccine development.

Key Market Players Profiled:

  • Agilent Technologies, Inc.
  • Bio-Rad Laboratories, Inc.
  • Thermo Fisher Scientific, Inc.
  • Merck KGaA
  • New England BioLabs, Inc.
  • Promega Corporation
  • QIAGEN GmbH
  • Takara Bio, Inc.
  • Oxford Expression Technologies Ltd
  • LGC Genomics Limited

Report Scope:

In this report, the Global Protein Expression Market has been segmented into the following categories:

By Expression System:

  • Prokaryotic
  • Mammalian Cell
  • Insect Cell
  • Yeast
  • Others

By Product:

  • Reagents
  • Competent Cells
  • Expression Vectors
  • Services
  • Instruments

By End user:

  • Pharmaceutical and Biotechnological Companies
  • Academic Research
  • Contract research organizations
  • Others

By Region:

  • North America
  • Europe
  • Asia-Pacific
  • South America
  • Middle East & Africa

Competitive Landscape

Company Profiles: Detailed analysis of the major companies present in the Global Protein Expression Market.

Available Customizations:

With the given market data, the publisher offers customizations according to a company's specific needs. The following customization options are available for the report.

Company Information

  • Detailed analysis and profiling of additional market players (up to five).

This product will be delivered within 1-3 business days.

Table of Contents

1. Product Overview
1.1. Market Definition
1.2. Scope of the Market
1.2.1. Markets Covered
1.2.2. Years Considered for Study
1.2.3. Key Market Segmentations
2. Research Methodology
2.1. Objective of the Study
2.2. Baseline Methodology
2.3. Key Industry Partners
2.4. Major Association and Secondary Sources
2.5. Forecasting Methodology
2.6. Data Triangulation & Validation
2.7. Assumptions and Limitations
3. Executive Summary
3.1. Overview of the Market
3.2. Overview of Key Market Segmentations
3.3. Overview of Key Market Players
3.4. Overview of Key Regions/Countries
3.5. Overview of Market Drivers, Challenges, Trends
4. Voice of Customer
5. Global Protein Expression Market Outlook
5.1. Market Size & Forecast
5.1.1. By Value
5.2. Market Share & Forecast
5.2.1. By Expression System (Prokaryotic, Mammalian Cell, Insect Cell, Yeast, Others)
5.2.2. By Product (Reagents, Competent Cells, Expression Vectors, Services, Instruments)
5.2.3. By End user (Pharmaceutical and Biotechnological Companies, Academic Research, Contract research organizations, Others)
5.2.4. By Region
5.2.5. By Company (2024)
5.3. Market Map
6. North America Protein Expression Market Outlook
6.1. Market Size & Forecast
6.1.1. By Value
6.2. Market Share & Forecast
6.2.1. By Expression System
6.2.2. By Product
6.2.3. By End user
6.2.4. By Country
6.3. North America: Country Analysis
6.3.1. United States Protein Expression Market Outlook
6.3.1.1. Market Size & Forecast
6.3.1.1.1. By Value
6.3.1.2. Market Share & Forecast
6.3.1.2.1. By Expression System
6.3.1.2.2. By Product
6.3.1.2.3. By End user
6.3.2. Canada Protein Expression Market Outlook
6.3.2.1. Market Size & Forecast
6.3.2.1.1. By Value
6.3.2.2. Market Share & Forecast
6.3.2.2.1. By Expression System
6.3.2.2.2. By Product
6.3.2.2.3. By End user
6.3.3. Mexico Protein Expression Market Outlook
6.3.3.1. Market Size & Forecast
6.3.3.1.1. By Value
6.3.3.2. Market Share & Forecast
6.3.3.2.1. By Expression System
6.3.3.2.2. By Product
6.3.3.2.3. By End user
7. Europe Protein Expression Market Outlook
7.1. Market Size & Forecast
7.1.1. By Value
7.2. Market Share & Forecast
7.2.1. By Expression System
7.2.2. By Product
7.2.3. By End user
7.2.4. By Country
7.3. Europe: Country Analysis
7.3.1. Germany Protein Expression Market Outlook
7.3.1.1. Market Size & Forecast
7.3.1.1.1. By Value
7.3.1.2. Market Share & Forecast
7.3.1.2.1. By Expression System
7.3.1.2.2. By Product
7.3.1.2.3. By End user
7.3.2. France Protein Expression Market Outlook
7.3.2.1. Market Size & Forecast
7.3.2.1.1. By Value
7.3.2.2. Market Share & Forecast
7.3.2.2.1. By Expression System
7.3.2.2.2. By Product
7.3.2.2.3. By End user
7.3.3. United Kingdom Protein Expression Market Outlook
7.3.3.1. Market Size & Forecast
7.3.3.1.1. By Value
7.3.3.2. Market Share & Forecast
7.3.3.2.1. By Expression System
7.3.3.2.2. By Product
7.3.3.2.3. By End user
7.3.4. Italy Protein Expression Market Outlook
7.3.4.1. Market Size & Forecast
7.3.4.1.1. By Value
7.3.4.2. Market Share & Forecast
7.3.4.2.1. By Expression System
7.3.4.2.2. By Product
7.3.4.2.3. By End user
7.3.5. Spain Protein Expression Market Outlook
7.3.5.1. Market Size & Forecast
7.3.5.1.1. By Value
7.3.5.2. Market Share & Forecast
7.3.5.2.1. By Expression System
7.3.5.2.2. By Product
7.3.5.2.3. By End user
8. Asia-Pacific Protein Expression Market Outlook
8.1. Market Size & Forecast
8.1.1. By Value
8.2. Market Share & Forecast
8.2.1. By Expression System
8.2.2. By Product
8.2.3. By End user
8.2.4. By Country
8.3. Asia-Pacific: Country Analysis
8.3.1. China Protein Expression Market Outlook
8.3.1.1. Market Size & Forecast
8.3.1.1.1. By Value
8.3.1.2. Market Share & Forecast
8.3.1.2.1. By Expression System
8.3.1.2.2. By Product
8.3.1.2.3. By End user
8.3.2. India Protein Expression Market Outlook
8.3.2.1. Market Size & Forecast
8.3.2.1.1. By Value
8.3.2.2. Market Share & Forecast
8.3.2.2.1. By Expression System
8.3.2.2.2. By Product
8.3.2.2.3. By End user
8.3.3. Japan Protein Expression Market Outlook
8.3.3.1. Market Size & Forecast
8.3.3.1.1. By Value
8.3.3.2. Market Share & Forecast
8.3.3.2.1. By Expression System
8.3.3.2.2. By Product
8.3.3.2.3. By End user
8.3.4. South Korea Protein Expression Market Outlook
8.3.4.1. Market Size & Forecast
8.3.4.1.1. By Value
8.3.4.2. Market Share & Forecast
8.3.4.2.1. By Expression System
8.3.4.2.2. By Product
8.3.4.2.3. By End user
8.3.5. Australia Protein Expression Market Outlook
8.3.5.1. Market Size & Forecast
8.3.5.1.1. By Value
8.3.5.2. Market Share & Forecast
8.3.5.2.1. By Expression System
8.3.5.2.2. By Product
8.3.5.2.3. By End user
9. Middle East & Africa Protein Expression Market Outlook
9.1. Market Size & Forecast
9.1.1. By Value
9.2. Market Share & Forecast
9.2.1. By Expression System
9.2.2. By Product
9.2.3. By End user
9.2.4. By Country
9.3. Middle East & Africa: Country Analysis
9.3.1. Saudi Arabia Protein Expression Market Outlook
9.3.1.1. Market Size & Forecast
9.3.1.1.1. By Value
9.3.1.2. Market Share & Forecast
9.3.1.2.1. By Expression System
9.3.1.2.2. By Product
9.3.1.2.3. By End user
9.3.2. UAE Protein Expression Market Outlook
9.3.2.1. Market Size & Forecast
9.3.2.1.1. By Value
9.3.2.2. Market Share & Forecast
9.3.2.2.1. By Expression System
9.3.2.2.2. By Product
9.3.2.2.3. By End user
9.3.3. South Africa Protein Expression Market Outlook
9.3.3.1. Market Size & Forecast
9.3.3.1.1. By Value
9.3.3.2. Market Share & Forecast
9.3.3.2.1. By Expression System
9.3.3.2.2. By Product
9.3.3.2.3. By End user
10. South America Protein Expression Market Outlook
10.1. Market Size & Forecast
10.1.1. By Value
10.2. Market Share & Forecast
10.2.1. By Expression System
10.2.2. By Product
10.2.3. By End user
10.2.4. By Country
10.3. South America: Country Analysis
10.3.1. Brazil Protein Expression Market Outlook
10.3.1.1. Market Size & Forecast
10.3.1.1.1. By Value
10.3.1.2. Market Share & Forecast
10.3.1.2.1. By Expression System
10.3.1.2.2. By Product
10.3.1.2.3. By End user
10.3.2. Colombia Protein Expression Market Outlook
10.3.2.1. Market Size & Forecast
10.3.2.1.1. By Value
10.3.2.2. Market Share & Forecast
10.3.2.2.1. By Expression System
10.3.2.2.2. By Product
10.3.2.2.3. By End user
10.3.3. Argentina Protein Expression Market Outlook
10.3.3.1. Market Size & Forecast
10.3.3.1.1. By Value
10.3.3.2. Market Share & Forecast
10.3.3.2.1. By Expression System
10.3.3.2.2. By Product
10.3.3.2.3. By End user
11. Market Dynamics
11.1. Drivers
11.2. Challenges
12. Market Trends & Developments
12.1. Merger & Acquisition (If Any)
12.2. Product Launches (If Any)
12.3. Recent Developments
13. Global Protein Expression Market: SWOT Analysis
14. Porter's Five Forces Analysis
14.1. Competition in the Industry
14.2. Potential of New Entrants
14.3. Power of Suppliers
14.4. Power of Customers
14.5. Threat of Substitute Products
15. Competitive Landscape
15.1. Agilent Technologies, Inc.
15.1.1. Business Overview
15.1.2. Products & Services
15.1.3. Recent Developments
15.1.4. Key Personnel
15.1.5. SWOT Analysis
15.2. Bio-Rad Laboratories, Inc.
15.3. Thermo Fisher Scientific, Inc.
15.4. Merck KGaA
15.5. New England BioLabs, Inc.
15.6. Promega Corporation
15.7. QIAGEN GmbH
15.8. Takara Bio, Inc.
15.9. Oxford Expression Technologies Ltd
15.10. LGC Genomics Limited
16. Strategic Recommendations17. About the Publisher & Disclaimer

Companies Mentioned

The companies profiled in this Protein Expression market report include:
  • Agilent Technologies, Inc.
  • Bio-Rad Laboratories, Inc.
  • Thermo Fisher Scientific, Inc.
  • Merck KGaA
  • New England BioLabs, Inc.
  • Promega Corporation
  • QIAGEN GmbH
  • Takara Bio, Inc.
  • Oxford Expression Technologies Ltd
  • LGC Genomics Limited

Table Information