The closed system transfer devices market size has grown rapidly in recent years. It will grow from $1.18 billion in 2025 to $1.35 billion in 2026 at a compound annual growth rate (CAGR) of 14.2%. The growth in the historic period can be attributed to increasing use of hazardous drugs in oncology, rising awareness of occupational exposure risks, implementation of safety guidelines for drug handling, expansion of hospital oncology services, growing adoption of chemotherapy infusion therapies.
The closed system transfer devices market size is expected to see rapid growth in the next few years. It will grow to $2.18 billion in 2030 at a compound annual growth rate (CAGR) of 12.6%. The growth in the forecast period can be attributed to stricter regulatory enforcement for hazardous drug handling, rising cancer treatment volumes, growing emphasis on workplace safety compliance, expansion of oncology centers globally, increasing investment in hospital pharmacy safety infrastructure. Major trends in the forecast period include rising adoption of closed drug handling systems in oncology, increasing focus on healthcare worker safety and exposure reduction, growing preference for needleless closed transfer systems, expansion of cstd usage across hospital pharmacies, increasing standardization of hazardous drug handling protocols.
The rising incidence of cancer is expected to drive the growth of the closed-system transfer devices market in the coming years. Cancer is a disease characterized by the uncontrolled growth of abnormal cells, which can invade nearby tissues and spread through the blood and lymph systems to other parts of the body. The prevalence of cancer is increasing due to various factors, including lifestyle choices, environmental exposures, and higher rates of infections. Closed-system transfer devices are crucial in cancer treatment as they help protect healthcare workers and patients from the dangers associated with handling and administering chemotherapy drugs. These devices contribute to a safer healthcare environment and improve treatment outcomes for cancer patients. For example, the World Health Organization (WHO), a Switzerland-based intergovernmental organization, projected in February 2024 that by 2050, global cancer cases will surpass 35 million, marking a 77% increase from the 20 million cases expected in 2022. This significant rise underscores the growing cancer burden worldwide. Additionally, the National Center for Biotechnology Information (NCBI), a US-based intergovernmental organization, reported in January 2023 that there were 1,958,310 new cancer cases in the United States, with 609,820 cancer-related deaths projected for 2023. Therefore, the increasing number of cancer cases is driving the demand for closed-system transfer devices.
Leading companies in the closed-system transfer devices (CSTD) market are focusing on developing innovative syringe units to enhance safety, improve user experience, reduce contamination risks, and ensure compliance with strict regulatory standards in the healthcare industry. A syringe unit designed for full-volume use is meant to deliver the entire volume of a liquid or medication without the need for additional mixing or dilution. For example, in October 2023, Equashield, a US-based medical device company, introduced the EQUASHIELD Syringe Unit, which received FDA clearance for full-volume use. This design ensures safer and more efficient handling of hazardous drugs by preventing vapor escape and plunger contamination, providing a cost-effective solution for compounding and administering medications.
In December 2024, Equashield Medical Ltd., a US-based medical device company, partnered with Pharmacy Stars to improve safety and compliance in medication compounding across healthcare facilities. Through this collaboration, the companies seek to combine EQUASHIELD’s hazardous drug-handling technologies with Pharmacy Stars’ Compounding360 platform to enhance contamination control, simplify regulatory compliance, and boost operational efficiency for pharmacies. Pharmacy Stars is a US-based health technology company that specializes in compounding quality management solutions.
Major companies operating in the closed system transfer devices market are Cardinal Health Inc., Becton Dickinson and Company, Baxter International Inc., B Braun Melsungen AG, Terumo Corporation, ICU Medical Inc., Amsino International Inc., JMS Co. Ltd., Vygon SA, Codan Medical GmbH, Equashield LLC, Hospira Inc., Nipro Corporation, Simplivia Healthcare Ltd., Practivet Inc., Corvida Medical Inc., Yukon Medical, Caragen Ltd., Insung Medical Co. Ltd., Aegis Medical Technologies, Epic Medical Pte Ltd., Smiths Medical.
North America was the largest region in the closed system transfer device market in 2025. Asia-Pacific is expected to be the fastest-growing region in the forecast period. The regions covered in the closed system transfer devices market report are Asia-Pacific, South East Asia, Western Europe, Eastern Europe, North America, South America, Middle East, Africa. The countries covered in the closed system transfer devices market report are Australia, Brazil, China, France, Germany, India, Indonesia, Japan, Taiwan, Russia, South Korea, UK, USA, Canada, Italy, Spain.
Tariffs are impacting the closed system transfer devices market by increasing costs for imported medical-grade plastics, valves, membranes, and precision components used in needleless and membrane-to-membrane systems. These cost pressures have particularly affected advanced closing mechanism segments, with north america and asia-pacific regions experiencing greater exposure due to global sourcing dependencies. Higher tariffs have raised procurement costs for hospitals and oncology centers and influenced purchasing cycles. However, tariffs have also encouraged local manufacturing, supplier diversification, and simplified device designs, strengthening long-term supply chain resilience.
The closed system transfer devices market research report is one of a series of new reports that provides closed system transfer devices market statistics, including closed system transfer devices industry global market size, regional shares, competitors with a closed system transfer devices market share, detailed closed system transfer devices market segments, market trends and opportunities, and any further data you may need to thrive in the closed system transfer devices industry. This closed system transfer devices market research report delivers a complete perspective of everything you need, with an in-depth analysis of the current and future scenario of the industry.
Closed system transfer devices (CSTDs) are specialized tools used for transferring drugs while mechanically preventing environmental contaminants from entering and hazardous drugs or vapors from escaping. They establish a closed, leak-proof system to ensure the safe handling of hazardous substances in healthcare settings.
There are two main types of closed-system transfer devices, needleless systems and membrane-to-membrane systems. The latter refers to a lipid membrane model commonly employed in scientific research to study biological membrane characteristics and dynamics. These devices utilize various technologies such as diaphragm-based, compartmentalized, and filtration mechanisms, often integrated with closing mechanisms such as color-to-color alignment, push-to-turn, click-to-lock, and luer-lock systems. They are utilized by diverse end-users including hospitals, clinics, oncology centers, and other healthcare facilities.
The closed system transfer devices market consists of sales of closed vial access devices (CVADs), closed syringe transfer systems, closed bag systems, and closed ampoule systems. Values in this market are ‘factory gate’ values, that is the value of goods sold by the manufacturers or creators of the goods, whether to other entities (including downstream manufacturers, wholesalers, distributors, and retailers) or directly to end customers. The value of goods in this market includes related services sold by the creators of the goods.
The market value is defined as the revenues that enterprises gain from the sale of goods and/or services within the specified market and geography through sales, grants, or donations in terms of the currency (in USD unless otherwise specified).
The revenues for a specified geography are consumption values that are revenues generated by organizations in the specified geography within the market, irrespective of where they are produced. It does not include revenues from resales along the supply chain, either further along the supply chain or as part of other products.
This product will be delivered within 1-3 business days.
The closed system transfer devices market size is expected to see rapid growth in the next few years. It will grow to $2.18 billion in 2030 at a compound annual growth rate (CAGR) of 12.6%. The growth in the forecast period can be attributed to stricter regulatory enforcement for hazardous drug handling, rising cancer treatment volumes, growing emphasis on workplace safety compliance, expansion of oncology centers globally, increasing investment in hospital pharmacy safety infrastructure. Major trends in the forecast period include rising adoption of closed drug handling systems in oncology, increasing focus on healthcare worker safety and exposure reduction, growing preference for needleless closed transfer systems, expansion of cstd usage across hospital pharmacies, increasing standardization of hazardous drug handling protocols.
The rising incidence of cancer is expected to drive the growth of the closed-system transfer devices market in the coming years. Cancer is a disease characterized by the uncontrolled growth of abnormal cells, which can invade nearby tissues and spread through the blood and lymph systems to other parts of the body. The prevalence of cancer is increasing due to various factors, including lifestyle choices, environmental exposures, and higher rates of infections. Closed-system transfer devices are crucial in cancer treatment as they help protect healthcare workers and patients from the dangers associated with handling and administering chemotherapy drugs. These devices contribute to a safer healthcare environment and improve treatment outcomes for cancer patients. For example, the World Health Organization (WHO), a Switzerland-based intergovernmental organization, projected in February 2024 that by 2050, global cancer cases will surpass 35 million, marking a 77% increase from the 20 million cases expected in 2022. This significant rise underscores the growing cancer burden worldwide. Additionally, the National Center for Biotechnology Information (NCBI), a US-based intergovernmental organization, reported in January 2023 that there were 1,958,310 new cancer cases in the United States, with 609,820 cancer-related deaths projected for 2023. Therefore, the increasing number of cancer cases is driving the demand for closed-system transfer devices.
Leading companies in the closed-system transfer devices (CSTD) market are focusing on developing innovative syringe units to enhance safety, improve user experience, reduce contamination risks, and ensure compliance with strict regulatory standards in the healthcare industry. A syringe unit designed for full-volume use is meant to deliver the entire volume of a liquid or medication without the need for additional mixing or dilution. For example, in October 2023, Equashield, a US-based medical device company, introduced the EQUASHIELD Syringe Unit, which received FDA clearance for full-volume use. This design ensures safer and more efficient handling of hazardous drugs by preventing vapor escape and plunger contamination, providing a cost-effective solution for compounding and administering medications.
In December 2024, Equashield Medical Ltd., a US-based medical device company, partnered with Pharmacy Stars to improve safety and compliance in medication compounding across healthcare facilities. Through this collaboration, the companies seek to combine EQUASHIELD’s hazardous drug-handling technologies with Pharmacy Stars’ Compounding360 platform to enhance contamination control, simplify regulatory compliance, and boost operational efficiency for pharmacies. Pharmacy Stars is a US-based health technology company that specializes in compounding quality management solutions.
Major companies operating in the closed system transfer devices market are Cardinal Health Inc., Becton Dickinson and Company, Baxter International Inc., B Braun Melsungen AG, Terumo Corporation, ICU Medical Inc., Amsino International Inc., JMS Co. Ltd., Vygon SA, Codan Medical GmbH, Equashield LLC, Hospira Inc., Nipro Corporation, Simplivia Healthcare Ltd., Practivet Inc., Corvida Medical Inc., Yukon Medical, Caragen Ltd., Insung Medical Co. Ltd., Aegis Medical Technologies, Epic Medical Pte Ltd., Smiths Medical.
North America was the largest region in the closed system transfer device market in 2025. Asia-Pacific is expected to be the fastest-growing region in the forecast period. The regions covered in the closed system transfer devices market report are Asia-Pacific, South East Asia, Western Europe, Eastern Europe, North America, South America, Middle East, Africa. The countries covered in the closed system transfer devices market report are Australia, Brazil, China, France, Germany, India, Indonesia, Japan, Taiwan, Russia, South Korea, UK, USA, Canada, Italy, Spain.
Tariffs are impacting the closed system transfer devices market by increasing costs for imported medical-grade plastics, valves, membranes, and precision components used in needleless and membrane-to-membrane systems. These cost pressures have particularly affected advanced closing mechanism segments, with north america and asia-pacific regions experiencing greater exposure due to global sourcing dependencies. Higher tariffs have raised procurement costs for hospitals and oncology centers and influenced purchasing cycles. However, tariffs have also encouraged local manufacturing, supplier diversification, and simplified device designs, strengthening long-term supply chain resilience.
The closed system transfer devices market research report is one of a series of new reports that provides closed system transfer devices market statistics, including closed system transfer devices industry global market size, regional shares, competitors with a closed system transfer devices market share, detailed closed system transfer devices market segments, market trends and opportunities, and any further data you may need to thrive in the closed system transfer devices industry. This closed system transfer devices market research report delivers a complete perspective of everything you need, with an in-depth analysis of the current and future scenario of the industry.
Closed system transfer devices (CSTDs) are specialized tools used for transferring drugs while mechanically preventing environmental contaminants from entering and hazardous drugs or vapors from escaping. They establish a closed, leak-proof system to ensure the safe handling of hazardous substances in healthcare settings.
There are two main types of closed-system transfer devices, needleless systems and membrane-to-membrane systems. The latter refers to a lipid membrane model commonly employed in scientific research to study biological membrane characteristics and dynamics. These devices utilize various technologies such as diaphragm-based, compartmentalized, and filtration mechanisms, often integrated with closing mechanisms such as color-to-color alignment, push-to-turn, click-to-lock, and luer-lock systems. They are utilized by diverse end-users including hospitals, clinics, oncology centers, and other healthcare facilities.
The closed system transfer devices market consists of sales of closed vial access devices (CVADs), closed syringe transfer systems, closed bag systems, and closed ampoule systems. Values in this market are ‘factory gate’ values, that is the value of goods sold by the manufacturers or creators of the goods, whether to other entities (including downstream manufacturers, wholesalers, distributors, and retailers) or directly to end customers. The value of goods in this market includes related services sold by the creators of the goods.
The market value is defined as the revenues that enterprises gain from the sale of goods and/or services within the specified market and geography through sales, grants, or donations in terms of the currency (in USD unless otherwise specified).
The revenues for a specified geography are consumption values that are revenues generated by organizations in the specified geography within the market, irrespective of where they are produced. It does not include revenues from resales along the supply chain, either further along the supply chain or as part of other products.
This product will be delivered within 1-3 business days.
Table of Contents
1. Executive Summary
2. Closed System Transfer Devices Market Characteristics
3. Closed System Transfer Devices Market Supply Chain Analysis
4. Global Closed System Transfer Devices Market Trends and Strategies
5. Closed System Transfer Devices Market Analysis of End Use Industries
7. Global Closed System Transfer Devices Strategic Analysis Framework, Current Market Size, Market Comparisons and Growth Rate Analysis
8. Global Closed System Transfer Devices Total Addressable Market (TAM) Analysis for the Market
9. Closed System Transfer Devices Market Segmentation
10. Closed System Transfer Devices Market Regional and Country Analysis
11. Asia-Pacific Closed System Transfer Devices Market
12. China Closed System Transfer Devices Market
13. India Closed System Transfer Devices Market
14. Japan Closed System Transfer Devices Market
15. Australia Closed System Transfer Devices Market
16. Indonesia Closed System Transfer Devices Market
17. South Korea Closed System Transfer Devices Market
18. Taiwan Closed System Transfer Devices Market
19. South East Asia Closed System Transfer Devices Market
20. Western Europe Closed System Transfer Devices Market
21. UK Closed System Transfer Devices Market
22. Germany Closed System Transfer Devices Market
23. France Closed System Transfer Devices Market
24. Italy Closed System Transfer Devices Market
25. Spain Closed System Transfer Devices Market
26. Eastern Europe Closed System Transfer Devices Market
27. Russia Closed System Transfer Devices Market
28. North America Closed System Transfer Devices Market
29. USA Closed System Transfer Devices Market
30. Canada Closed System Transfer Devices Market
31. South America Closed System Transfer Devices Market
32. Brazil Closed System Transfer Devices Market
33. Middle East Closed System Transfer Devices Market
34. Africa Closed System Transfer Devices Market
36. Closed System Transfer Devices Market Competitive Landscape and Company Profiles
37. Closed System Transfer Devices Market Other Major and Innovative Companies
40. Closed System Transfer Devices Market High Potential Countries, Segments and Strategies
41. Appendix
List of Tables
Executive Summary
Closed System Transfer Devices Market Global Report 2026 provides strategists, marketers and senior management with the critical information they need to assess the market.This report focuses closed system transfer devices market which is experiencing strong growth. The report gives a guide to the trends which will be shaping the market over the next ten years and beyond.
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Description
Where is the largest and fastest growing market for closed system transfer devices? How does the market relate to the overall economy, demography and other similar markets? What forces will shape the market going forward, including technological disruption, regulatory shifts, and changing consumer preferences? The closed system transfer devices market global report answers all these questions and many more.The report covers market characteristics, size and growth, segmentation, regional and country breakdowns, total addressable market (TAM), market attractiveness score (MAS), competitive landscape, market shares, company scoring matrix, trends and strategies for this market. It traces the market’s historic and forecast market growth by geography.
- The market characteristics section of the report defines and explains the market. This section also examines key products and services offered in the market, evaluates brand-level differentiation, compares product features, and highlights major innovation and product development trends.
- The supply chain analysis section provides an overview of the entire value chain, including key raw materials, resources, and supplier analysis. It also provides a list competitor at each level of the supply chain.
- The updated trends and strategies section analyses the shape of the market as it evolves and highlights emerging technology trends such as digital transformation, automation, sustainability initiatives, and AI-driven innovation. It suggests how companies can leverage these advancements to strengthen their market position and achieve competitive differentiation.
- The regulatory and investment landscape section provides an overview of the key regulatory frameworks, regularity bodies, associations, and government policies influencing the market. It also examines major investment flows, incentives, and funding trends shaping industry growth and innovation.
- The market size section gives the market size ($b) covering both the historic growth of the market, and forecasting its development.
- The forecasts are made after considering the major factors currently impacting the market. These include the technological advancements such as AI and automation, Russia-Ukraine war, trade tariffs (government-imposed import/export duties), elevated inflation and interest rates.
- The total addressable market (TAM) analysis section defines and estimates the market potential compares it with the current market size, and provides strategic insights and growth opportunities based on this evaluation.
- The market attractiveness scoring section evaluates the market based on a quantitative scoring framework that considers growth potential, competitive dynamics, strategic fit, and risk profile. It also provides interpretive insights and strategic implications for decision-makers.
- Market segmentations break down the market into sub markets.
- The regional and country breakdowns section gives an analysis of the market in each geography and the size of the market by geography and compares their historic and forecast growth.
- Expanded geographical coverage includes Taiwan and Southeast Asia, reflecting recent supply chain realignments and manufacturing shifts in the region. This section analyzes how these markets are becoming increasingly important hubs in the global value chain.
- The competitive landscape chapter gives a description of the competitive nature of the market, market shares, and a description of the leading companies. Key financial deals which have shaped the market in recent years are identified.
- The company scoring matrix section evaluates and ranks leading companies based on a multi-parameter framework that includes market share or revenues, product innovation, and brand recognition.
Report Scope
Markets Covered:
1) By Type: Needleless Systems; Membrane-To-Membrane Systems2) By Technology: Diaphragm-Based; Compartmentalized; Filtration
3) By Closing Mechanism: Color-To-Color Alignment Systems; Push-To-Turn Systems; Click-To-Lock Systems; Luer-Lock Systems
4) By End User: Hospitals And Clinics; Oncology Centers; Other End Users
Subsegments:
1) By Needleless Systems: Closed Vial Systems; Closed Syringe Systems; Transfer Device Adapters2) By Membrane-To-Membrane Systems: Membrane-To-Membrane Transfer Devices; Filtered Membrane Transfer Devices
Companies Mentioned: Cardinal Health Inc.; Becton Dickinson and Company; Baxter International Inc.; B Braun Melsungen AG; Terumo Corporation; ICU Medical Inc.; Amsino International Inc.; JMS Co. Ltd.; Vygon SA; Codan Medical GmbH; Equashield LLC; Hospira Inc.; Nipro Corporation; Simplivia Healthcare Ltd.; Practivet Inc.; Corvida Medical Inc.; Yukon Medical; Caragen Ltd.; Insung Medical Co. Ltd.; Aegis Medical Technologies; Epic Medical Pte Ltd.; Smiths Medical
Countries: Australia; Brazil; China; France; Germany; India; Indonesia; Japan; Taiwan; Russia; South Korea; UK; USA; Canada; Italy; Spain
Regions: Asia-Pacific; South East Asia; Western Europe; Eastern Europe; North America; South America; Middle East; Africa
Time Series: Five years historic and ten years forecast.
Data: Ratios of market size and growth to related markets, GDP proportions, expenditure per capita.
Data Segmentation: Country and regional historic and forecast data, market share of competitors, market segments.
Sourcing and Referencing: Data and analysis throughout the report is sourced using end notes.
Delivery Format: Word, PDF or Interactive Report + Excel Dashboard
Added Benefits:
- Bi-Annual Data Update
- Customisation
- Expert Consultant Support
Companies Mentioned
The companies featured in this Closed System Transfer Devices market report include:- Cardinal Health Inc.
- Becton Dickinson and Company
- Baxter International Inc.
- B Braun Melsungen AG
- Terumo Corporation
- ICU Medical Inc.
- Amsino International Inc.
- JMS Co. Ltd.
- Vygon SA
- Codan Medical GmbH
- Equashield LLC
- Hospira Inc.
- Nipro Corporation
- Simplivia Healthcare Ltd.
- Practivet Inc.
- Corvida Medical Inc.
- Yukon Medical
- Caragen Ltd.
- Insung Medical Co. Ltd.
- Aegis Medical Technologies
- Epic Medical Pte Ltd.
- Smiths Medical
Table Information
| Report Attribute | Details |
|---|---|
| No. of Pages | 250 |
| Published | February 2026 |
| Forecast Period | 2026 - 2030 |
| Estimated Market Value ( USD | $ 1.35 Billion |
| Forecasted Market Value ( USD | $ 2.18 Billion |
| Compound Annual Growth Rate | 12.6% |
| Regions Covered | Global |
| No. of Companies Mentioned | 23 |
