Airlift Bioreactors Market Report 2025

This Airlift Bioreactors market report provides a comprehensive analysis of the market’s characteristics, size, and growth, including segmentation, regional and country-level breakdowns, competitive landscape, market shares, trends, and strategies. It also tracks historical and forecasted market growth across various geographies.

The airlift bioreactors market size has grown rapidly in recent years. It will grow from $3.95 billion in 2024 to $4.38 billion in 2025 at a compound annual growth rate (CAGR) of 10.8%. The growth in the historic period can be attributed to increased demand for single-use bioreactors, an increased number of clinical and preclinical trials performed, an increased focus on bioprocessing efficiency, increased demand from contract research organizations (CROs) and contract development and manufacturing organizations (CMOs), and government support and regulations.

The airlift bioreactors market size is expected to see rapid growth in the next few years. It will grow to $6.5 billion in 2029 at a compound annual growth rate (CAGR) of 10.4%. The growth in the forecast period can be attributed to the growing output of various research and development activities for biochemicals, growing investments in healthcare, economic growth and development, growing awareness of the benefits of airlift bioreactors, and rising demand for customized and personalized medicines. Major trends in the forecast period include the emergence of new players, the use of airlift bioreactors in vaccine production, a growing focus on sustainability, demand for high-density cell culture, and a growing focus on regulatory compliance.

The increasing demand for biopharmaceutical products is expected to drive growth in the airlift bioreactors market. These products, derived from living organisms or produced through biotechnological processes such as recombinant DNA technology and cell cultures, are experiencing heightened demand due to advancements in cell culture technologies, rising incidence of chronic and age-related diseases, innovations in bioprocessing, and developments in genomics. Airlift bioreactors, known for their unique design and operational advantages, play a crucial role in producing therapeutic proteins, monoclonal antibodies, and vaccines. For example, as of August 2023, there were 2,760 developers of cell, gene, and tissue-engineering therapeutics worldwide, marking a 101% increase from 1,369 in the first quarter of 2022. Consequently, the growing demand for biopharmaceutical products is a key driver behind the expansion of the airlift bioreactors market.

Leading companies in the airlift bioreactor sector are focusing on advancing single-use bioreactors with airlift technology to enhance scalability, improve operational flexibility, and meet the increasing need for efficient and cost-effective bioprocessing solutions. Airlift technology in single-use bioreactors utilizes gases such as air or oxygen to circulate and mix the culture broth without mechanical agitation, capitalizing on density differences between gas-sparged (riser) and non-gas-sparged (downcomer) areas to create a natural circulation loop. For instance, Cellexus, a UK-based biotechnology firm, introduced innovative airlift single-use disposable bioreactor systems in March 2022. These systems replace mechanical mixing with bubble-driven circulation, ensuring optimal aeration and promoting rapid cell growth while minimizing mechanical shear forces typically associated with impeller-based systems.

In March 2022, Cellexus, a biotechnology company based in the UK that specializes in airlift bioreactors, entered into a partnership with Verder Liquids. The objective of this partnership is for Verder Liquids to provide pumps tailored for the acid or base systems integral to Cellexus's CellMaker Plus and Low Flow airlift bioreactor models. Verder Liquids, headquartered in the Netherlands, is renowned for its expertise in manufacturing displacement pumps.

Major companies operating in the airlift bioreactors market are Lonza Group AG, Sartorius AG, Cytiva, Zeta Global Corp., Shanghai Ritai Medicine Equipment Project Co. Ltd., Applikon Biotechnology, Kuhner Shaker Inc, Tecnal, bionet, Bailun Biotechnology Co.Ltd, ProAnalytics LLC, IVEN Pharmatech, Solida Biotech, LABOAO, Cellexus, Electrolab Biotech Ltd, Shree Biocare Solutions Pvt Ltd, BioReactor Sciences, Lab1st Scientific, Atlas Scientific, Cedarstone Industry, Belach Bioteknik AB, Biojenik Engineering, Vögtlin Instruments GmbH, OmniBRx Biotechnologies Pvt Ltd.

North America was the largest region in the airlift bioreactor market in 2024. The regions covered in the airlift bioreactors market report are Asia-Pacific, Western Europe, Eastern Europe, North America, South America, Middle East, Africa. The countries covered in the airlift bioreactors market report are Australia, Brazil, China, France, Germany, India, Indonesia, Japan, Russia, South Korea, UK, USA, Canada, Italy, Spain.

Airlift bioreactors are vertical tower reactors designed to facilitate large-scale aerobic cultures, utilizing an airlift pump to infuse gas into the culture broth for effective mixing. They find application in cultivating microorganisms, plant, and animal cells, particularly in sectors such as pharmaceuticals, enzyme production, and biofuels.

There are two primary types of airlift bioreactors, internal airlift loop bioreactors and external airlift loop bioreactors. The internal airlift loop bioreactor features a single vessel divided into interconnected zones - the riser and the downcomer - allowing for the circulation of liquid. These bioreactors come in various capacities, including 5 liters, 7 liters, 10 liters, and 30 liters, catering to different needs such as single-use, disposable, or reusable setups. They are deployed across laboratory, pilot, and large scales, serving diverse end-users such as biopharmaceutical companies, contract research organizations (CROs) or contract development and manufacturing organizations (CDMOs), as well as research and development firms.

The airlift bioreactors market research report is one of a series of new reports that provides airlift bioreactors market statistics, including airlift bioreactors industry global market size, regional shares, competitors with a airlift bioreactors market share, detailed airlift bioreactors market segments, market trends and opportunities, and any further data you may need to thrive in the airlift bioreactors industry. This airlift bioreactors market research report delivers a complete perspective of everything you need, with an in-depth analysis of the current and future scenario of the industry.

The airlift bioreactor market consists of sales of stainless steel and glass airlift bioreactors, bioplastics, bioactive compounds, level sensors. Values in this market are ‘factory gate’ values, that is, the value of goods sold by the manufacturers or creators of the goods, whether to other entities (including downstream manufacturers, wholesalers, distributors, and retailers) or directly to end customers. The value of goods in this market includes related services sold by the creators of the goods.

The market value is defined as the revenues that enterprises gain from the sale of goods and/or services within the specified market and geography through sales, grants, or donations in terms of the currency (in USD, unless otherwise specified).

The revenues for a specified geography are consumption values that are revenues generated by organizations in the specified geography within the market, irrespective of where they are produced. It does not include revenues from resales along the supply chain, either further along the supply chain or as part of other products.

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