Organ Preservation Market - Global Industry Size, Share, Trends, Opportunity, and Forecast, 2021-2031

The Global Organ Preservation Market is projected to expand from a valuation of USD 284.81 Million in 2025 to USD 387.16 Million by 2031, progressing at a CAGR of 5.25%. This market consists of advanced mechanical perfusion systems and specialized chemical solutions designed to sustain the physiological function and cellular viability of donor organs during storage and transport. Key factors driving this growth include the rising global incidence of chronic conditions, such as cardiovascular disorders and diabetes, which significantly heighten the risk of end-stage organ failure. Additionally, the increasing geriatric population, combined with clinical breakthroughs that allow for the transplantation of higher-risk donor organs, is fueling the demand for reliable preservation technologies to secure positive post-transplant results.

Despite these growth drivers, the market faces a substantial obstacle in the form of a persistent gap between the limited supply of viable donor organs and the high demand for transplants. This shortage restricts the total number of procedures, thereby limiting the addressable market for preservation solutions. Data from the United Network for Organ Sharing indicates that while a record 48,149 organ transplants were conducted in the United States in 2024 - a 3.3 percent rise from the prior year - this volume is still inadequate to meet the needs of the extensive waiting list of patients requiring life-saving surgeries.

Market Drivers

Technological breakthroughs in normothermic and hypothermic machine perfusion are transforming the industry by extending organ viability far beyond the limits of conventional static cold storage. These advanced mechanical systems provide continuous metabolic support and monitoring during transit, reducing ischemic damage and enabling the use of organs from extended criteria donors that were once considered unusable. The commercial success of these dynamic preservation methods is reflected in the financial performance of key industry players; for example, TransMedics Group, Inc. reported in October 2024 that their third-quarter net revenue surged to USD 108.8 million, a 64 percent increase year-over-year, largely attributed to the increased adoption of their proprietary organ care systems.

Simultaneously, government efforts and national strategies designed to boost donor registration are increasing the number of procedures that require preservation technologies. By streamlining donation processes and enhancing infrastructure, health authorities are effectively increasing organ availability, which in turn drives demand for transport units and preservation consumables. According to a July 2024 report by NHS Blood and Transplant, the United Kingdom saw the number of deceased donors rise to 1,510 in the 2023/24 fiscal year, a 6 percent increase. This rise in clinical activity is also spurring market consolidation, illustrated by Getinge AB's 2024 agreement to acquire Paragonix Technologies for approximately USD 477 million to incorporate advanced preservation devices into its medical portfolio.

Market Challenges

The severe shortage of appropriate donor organs remains a significant barrier to the expansion of the Global Organ Preservation Market. This ongoing imbalance between the finite supply of organs and the high demand for transplantation creates a ceiling on the industry's growth potential. Because preservation technologies are utilized only when an organ is procured for transport, market growth is inherently linked to donation rates rather than the sheer volume of patients suffering from end-stage organ failure. As a result, the market opportunity for these specialized perfusion systems and solutions is constrained by the limited number of transplant procedures actually performed.

The extent of this disparity highlights the severity of the issue, with the Association of Organ Procurement Organizations noting that over 104,000 patients are on the national waiting list for transplants in 2025. This figure emphasizes the disconnect between available resources and clinical necessity, as the number of candidates vastly outnumbers the donor pool. Consequently, revenue potential for manufacturers of preservation devices is capped, preventing the market from fully capitalizing on the demand suggested by the global prevalence of chronic diseases.

Market Trends

The market is being reshaped by the rise of outsourcing models and organ care services, moving the focus from capital equipment purchases to comprehensive logistical support. Transplant centers and hospitals are increasingly utilizing turnkey service networks that handle the entire process of organ retrieval, perfusion, and transport, significantly easing the operational load on surgical teams. This shift allows medical institutions to leverage advanced perfusion technologies without heavy upfront investments in hardware or specialized staff; illustrating this trend, Medical Buyer reported in October 2025 that TransMedics Group achieved a 32 percent quarterly revenue increase to USD 143.8 million, driven largely by the growing use of its National OCS Program (NOP) logistics network rather than console sales alone.

In parallel, the advancement of automated and portable organ transport systems is revolutionizing donor organ mobility and improving post-transplant outcomes. Unlike traditional static cold storage, these sophisticated devices actively regulate and monitor the organ's environment during transport, providing protection that substantially lowers long-term clinical risks. Integrating temperature control and continuous monitoring into a portable unit is yielding tangible survival benefits; the Organ Donation Alliance reported in June 2025 that data from the GUARDIAN-Heart Registry showed a 54 percent reduction in four-year mortality rates for hearts preserved with the Paragonix SherpaPak System compared to those transported using standard ice storage.

Key Players Profiled in the Organ Preservation Market

• Paragonix Technologies, Inc.
• XVIVO Perfusion AB
• Dr. Franz KOhler Chemie GmbH
• OrganOx Limited
• Bridge to Life (Europe) Ltd.
• Waters Medical Systems, LLC
• Preservation Solutions Inc.
• Artivion, Inc.
• Vascular Perfusion Solutions, Inc.
• Global Transplant Solutions

Report Scope

In this report, the Global Organ Preservation Market has been segmented into the following categories:

Organ Preservation Market, by Solution:

• University of Wisconsin Solution (UW Solution)
• Custodial HTK
• Perfadex
• Other Solutions

Organ Preservation Market, by Technique:

• Static Cold Storage
• Hypothermic Machine Perfusion
• Normothermic Machine Perfusion

Organ Preservation Market, by Organ Type:

• Kidney
• Liver
• Lung
• Heart
• Pancreas

Organ Preservation Market, by End User:

• Organ Transplant Centers
• Hospitals
• Specialty Clinics

Organ Preservation Market, by Region:

• North America
• Europe
• Asia-Pacific
• South America
• Middle East & Africa

Competitive Landscape

Company Profiles: Detailed analysis of the major companies present in the Global Organ Preservation Market.

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