Biotechnology Engineering: A Practical Approach on Bioprocess Development from Lab to Industrial Scale comprehensively provides consolidated content related to biotechnology engineering that supports R&D to manufacture commercial products on an industrial scale to meet the market's requirements. The book's structured chapters, practical approach, and real-world case studies effectively fulfil knowledge and information needs in the bioprocessing and biotechnology field. The chapters cover a broad diversity of topics ranging from the basics of bioprocessing, scalable solutions, bioprocess optimization, collaboration opportunities with experts, and crucial information on regulatory compliance. As such the book bridges the gap between theory and real-world applications in the bioprocessing field. Biotechnology Engineering: A Practical Approach on Bioprocess Development from Lab to Industrial Scale serves as a desktop reference for academics, scientist, engineers and professionals working on bioprocess development, discussing bioprocess development with calculations and case studies, and highlighting modern bioreactors and software tools adopted in the bioprocess industry.
Table of Contents
PART A: Cell culture and Kinetic study1. Culturing of microbial, animal and plant cells in lab scale
2. Microbial growth and cell kinetics
3. Design, optimization, and Inoculum development for culturing the cells
4. Lab scale studies on Submerged Liquid Fermentation (SLF) and Solid State Fermentation (SSF)
PART B: Bioreactor handling and operation
5. Fundamental of Bioreactors and accessories
6. Design Aspects and Aseptic Maintenance of Bioreactors
7. Cleaning Techniques for Bioreactors and Regulatory Standards
8. Bioreactor sterilization techniques and equipment
9. Standard Operating Procedures and Auditing in Bioprocess Industries
10. Operation and control of Submerged Liquid Fermenters
11. Operation and control of submerged solid fermenters
12. Equipment for downstream Product Recovery and Purification
13. Modern Reactors and Software Tools in Bioprocess Development
PART C: Bioreactor Scale up aspects and case studies
14. Scale-Up Rules and Reactor Accessories
15. Scale-Up Strategies for Submerged Liquid Fermentation
16. Scale-Up Strategies for Solid State Fermentation
17. Scale-Up Constraints from Lab Scale to Industrial Scale
PART D: Bioproducts
18. Commercial Bioproducts from Bioreactors
19. Bioproducts from Fermentation and their Economic Impact
20. Manufacturing Techniques for Bioproducts
Authors
Mohammad Hadi Dehghani Professor, Tehran University of Medical Sciences (TUMS), School of Public Health, Department of Environmental Health Engineering, Tehran, Iran. Prof. Dr. Mohammad Hadi Dehghani is a Full Professor at the Tehran University of Medical Sciences (TUMS), School of Public Health, Department of Environmental Health Engineering, Tehran, Islamic Republic of Iran. His scientific research interest includes environmental science. He is an editorial board member, guest editor, and reviewer in many internal and international journals and is a member of several international science committees around the world. He has authored or edited 16 books and more than 230 full papers published in peer-reviewed journals. Vinayaka B. Shet Assistant Professor, Department of Biotechnology Engineering, NMAMIT, Nitte, Karnataka, India. Dr Vinayaka B Shet is an Assistant Professor in the Department of Biotechnology Engineering, NMAMIT, Nitte (Deemed to be university), Nitte, Karnataka, India He received a Ph.D in Biotechnology from Visvesvaraya Technological University, India He has over 15 years of experience in Academics, 10 years in Research and 1 year in Industry His research interest includes the biomass pretreatment, fermentation, oenology, optimization, synthesis of nanoparticles and its applications He received young researcher award He has published over 30 papers, 7 book chapters and holding two Indian patent He is reviewer of various journals. Sandesh Kanthakere Assistant Professor, Department of Biotechnology Engineering, NMAMIT, Nitte, Karnataka, India. Dr Sandesh K is an Assistant Professor in the Department of Biotechnology Engineering, NMAMIT, Nitte (Deemed to be university), Nitte, Karnataka, India He received Ph.D from Visvesvaraya Technological University, India and masters in chemical plant design from National Institute of Technology, Surathkal, Karnataka, India He has more than 12 years of academic experience and 10 years of research experience He has 13 publications in reputed journals, 3 book chapters and holding one Indian patent His research area includes Bioprocess modeling and optimization, fermentation and kinetic study and ABE fermentation He is reviewer of journals Energy Engineering and management and biomass conversion and biorefinery. Nabisab Mujawar Mubarak Associate Professor, Department of Chemical Engineering, Curtin University, Sarawak Campus, Miri, Sarawak, Malaysia. Dr Mubarak Mujawar is currently an Associate Professor in the Department of Chemical Engineering at Curtin University, Sarawak Campus, Malaysia. His main research areas are carbon nanotube/nanofiber synthesis using microwave heating, synthesis of magnetic biochar and activated carbon using microwave technology, synthesis of biofuel using microwave heating, advanced materials syntheses such as hydro char, and graphene using microwave technology, functionalization of carbon nanotube for sensor application, application of CNTs and CNFs for removal liquids and gases pollutant, protein purification using carbon nanomaterials, immobilization of enzyme on carbon nanotubes and advanced material and reaction engineering etc. Rama Rao Karri Professor, Faculty of Engineering, University of Technology of Brunei, India.Dr. Rama Rao Karri is a professor (senior assistant) in the Faculty of Engineering at Universiti Teknologi Brunei. He has over 18 years of experience in academia, industry, and research. He has published 200+ research articles in reputed journals, book chapters, and conference proceedings.
