Biochemical Aspects of Metabolic Disorders offers a comprehensive exploration of the intricate biochemical mechanisms and/or pathways underlying a wide array of metabolic disorders. From the genetic basis of inherited metabolic conditions to the environmental factors impacting metabolic dysregulation, each chapter investigates the molecular insights essential for understanding and managing these complex diseases. Covering topics such as carbohydrate and lipid metabolism disorders, amino acid catabolism, hepatic and renal metabolism, mitochondrial dysfunction, pediatric obesity, and diagnostic approaches, this book will serve as a requisite resource for researchers, clinicians, and students alike looking for unravel the biochemical intricacies of metabolic disorders.
Table of Contents
1. Principles of Metabolic Disorders 2. Genetic Basis of Inherited Metabolic Disorders 3. Diagnostic Approaches for Detection of Biomarkers in Metabolic Disorders 4. Carbohydrate Metabolism Disorders 5. Lipid Metabolism Disorders 6. Amino Acid and Protein Metabolism Disorders 7. Metabolic Disorders Associated with Liver Dysfunction 8. Metabolic Disorders Associated with Kidney Dysfunction 9. Metabolic Disorders Associated with Pancreatic Dysfunction 10. Metabolic Disorders of Bone and Mineral Metabolism 11. Mitochondrial Dysfunction and Metabolic Disorders 12. Metabolic Disorders in Childhood 13. Molecular Insights into Oxidative Stress and Inflammatory Responses in Metabolic Disorders 14. Biochemical Perspectives on Environmental Factors Impacting Metabolic Dysregulation 15. Fatty Acid Oxidation Metabolism Disorders 16. Organic Acid Metabolism Disorders 17. Metabolic Crosstalk: Exploring the Dynamic Interactions Between Gut Microbiota and Metabolism 18. Epigenetic Insights into Metabolic Disorders: Illuminating the Molecular Complexity of Health and Disease 19. Nutritional Interventions in Metabolic Disorders: Optimizing Health Through Dietary Strategies
Authors
Muhammad Sajid Hamid Akash Associate Professor and Chairman at Department of Pharmaceutical Chemistry, Government College University Faisalabad (GCUF), Pakistan.
Dr. Akash is currently working as associate professor and chairman at Department of Pharmaceutical Chemistry, Government College University Faisalabad (GCUF), Pakistan. He got his bachelor and master's degrees in pharmacy from Bahauddin Zakariya University Multan, Pakistan and PhD degree in Pharmaceutical Analysis from Zhejiang University, China. Currently, he is focusing on investigating the effect of EDCs on various molecular and metabolic pathways that are involved in metabolic disorders and the treatment strategies of these EDCs-induced metabolic disorders funded by Higher Education Commission (HEC) of Pakistan. His Research work is the cutting edge and worthy of extension in developing countries like Pakistan, where it can be most beneficial and cost-effective especially for diabetic patients. Based on his significant scientific contributions in the field of Pharmaceutical Sciences, he has been awarded "Research Productivity Award� from Pakistan Council for Science and Technology (PCST), PAS Gold Medal from Pakistan Academy of Sciences and A.R. Shakoori Gold Medal from Zoological Society of Pakistan.
Kanwal Rehman Associate Professor, Department of Pharmacy in The Women University, Multan, Pakistan.
Dr. Kanwal Rehman PhD is working as Associate Professor at Department of Pharmacy in The Women University, Multan, Pakistan. Dr. Kanwal Rehman received her PhD in Pharmacology and Toxicology from Zhejiang University, Hangzhou, China in 2015. She nurtures a keen interest in pathogenesis of metabolic disorders like diabetes mellitus, obesity, and new therapeutic modalities for its treatment. Other work includes detection of environmental pollutants and their cytotoxic effects. She has published about 135 articles. She has also published 50 book chapters with international publishers and 4 books with Springer-Nature. Currently, she is focusing on the investigation of role of pharmacogenomics based upon gene polymorphism on various molecular and metabolic pathways that are involved in mitogenic disorders and treatment strategies like natural biogenic compounds against different risk factors of metabolic disorders including pancreatitis, cardiometabolic disorders and hormonal imbalance. Dr. Kanwal Rehman has also been awarded Research productivity award by Pakistan Council for Science and Technology (PCST), Pakistan.
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