Chapter 1 Executive Summary
- Market Outlook
- Scope of Report
- Market Summary
Chapter 2 Market Overview
- Overview
- Market and Technology Background
- A Brief History of CAR T-Cell Therapy
- FDA Product Approvals
- Other CAR T-Cell Therapies
- Clinical Applications of CAR T-Cell Therapy
- Adoptive Cell Transfer (ACT) Technologies
Chapter 3 Market Dynamics
- Market Dynamics
- Market Drivers
- Increasing Incidence of Cancer
- Growing Investments and Funding in CAR T-Cell Therapy Research
- Robust R&D Pipeline
- Advances in Genetic Engineering
- Market Restraints
- Complex Legislative and Regulatory Procedures
- Alternative Products from Competitors
- Market Opportunities
- Growing Significance of Precision Medicine
- Expanding Applications for CAR T-Cell Therapy
- Market Challenges
- Complex Manufacturing and Supply Chain
- Reimbursement Challenges for CAR T-Cell Therapy
Chapter 4 Emerging Technologies and Clinical Trials
- Introduction
- Clinical Trials Being Conducted Globally
- Distribution of CAR T-Cell Clinical Trials in China
Chapter 5 Market Segmentation Analysis
- Key Takeaways
- Segmentation Breakdown
- Global Market for CAR T-Cell Therapy, by Product
- Yescarta
- Kymriah
- Tecartus
- Abecma
- Breyanzi
- Carvykti
- Global Market for CAR T-Cell Therapy, by Indication
- Geographic Breakdown
- Global Market for CAR T-Cell Therapy, by Region
- North America
- Europe
- Asia-Pacific
- Rest of the World
Chapter 6 Patent Review and New Developments
- Introduction
- Anticipated Increase in Patent Litigation on Customized Patient Treatments
- Company-specific Intellectual Property and Patent Information
- Amgen
- Avacta Life Sciences Ltd.
- Bluebird Bio
- Celgene Corp.
- Cellectis
- Celyad SA
- Editas Medicine Inc.
- Eureka Therapeutics Inc.
- iCell Gene Therapeutics
- Juno Therapeutics Inc. (A Celgene Co.)
- Noile-Immune Biotech
- Novartis AG
Chapter 7 Competitive Intelligence
- Ranking of Leading Players
- Strategic Considerations
Chapter 8 Sustainability in the CAR T-Cell Therapy Market: ESG Perspective
- Introduction to ESG
- Role of ESG in the Pharma Industry
- ESG Performance Analysis
- Environmental
- Social
- Governance
- ESG Risk Ratings
- Conclusion
List of Tables
Summary Table: Global Market for CAR T-Cell Therapy, by Product, Through 2029
Table 1: U.S. FDA-approved CAR T-cell Therapies, 2017-2022
Table 2: Summary Classification of Tumors of the Hematopoietic and Lymphoid Tissues
Table 3: Tumor-Associated Antigens of CAR T-Cell Targets
Table 4: Global Cancer Statistics, 2022
Table 5: Clinical Trials of CAR T-Cell Therapy, by Select Countries, January 2023
Table 6: CAR T-Cell Therapy Clinical Trials Distribution, by Investigators and Collaborators, January 2023
Table 7: Emerging CAR T-Cell Therapy Clinical Trials, by Company
Table 8: Clinical Trials on CD19 Directed CAR T Cells in the U.S.
Table 9: Examples of Clinical Trials on CD19-Directed CAR T Cells in China
Table 10: Examples of Clinical Trials on CAR T Cells Targeting Non-CD19 Antigens in China
Table 11: Examples of Clinical Trials on CAR T Cells for Solid Tumors in China
Table 12: Clinical Trials on CAR T Cells with Fourth-Generation CARs in China
Table 13: Global Market for CAR T-Cell Therapy, by Product, Through 2029
Table 14: Global Market for CAR T-Cell Therapy, by Indication, Through 2029
Table 15: Clinical Trials of CAR T-cell Therapy in Other Indications
Table 16: Global Market for CAR T-Cell Therapy, by Region, Through 2029
Table 17: Bluebird Bio: Patents and Patent Applications, 2012-2021
Table 18: Celgene Corp.: Patents and Patent Applications, 2018-2021
Table 19: Cellectis: Patents and Patent Applications, 2018-2021
Table 20: Editas Medicine: Patent Applications, 2015-2021
Table 21: Eureka Therapeutics: Patent Applications, 2012-2021
Table 22: iCell Gene Therapeutics: Patent Applications, 2017-2019
Table 23: Juno Therapeutics Inc. and Memorial Sloan Kettering Cancer Center: Patents and Patent Applications, 2000-2021
Table 24: Noile-Immune Biotech Inc. Yamaguchi University Patent Applications, 2017
Table 25: Novartis AG and University of Pennsylvania: Patents and Patent Applications, 2013-2021
Table 26: Leading Companies in the CAR T-Cell Therapy Market, 2023
Table 27: Focus Areas in ESG Metrics
Table 28: ESG Risk Rankings for CAR T-Cell Therapy Companies, 2024*
Table 29: Abbreviations Used in this Report
Table 30: AbbVie Inc.: Company Snapshot
Table 31: AbbVie Inc.: Financial Performance, FY 2022 and 2023
Table 32: AbbVie Inc.: Product Portfolio
Table 33: AbbVie Inc.: News/Key Developments, 2023-2024
Table 34: Allogene Therapeutics: Company Snapshot
Table 35: Allogene Therapeutics: Financial Performance, FY 2022 and 2023
Table 36: Allogene Therapeutics: Product Portfolio
Table 37: Allogene Therapeutics: News/Key Developments, 2024
Table 38: Amgen Inc.: Company Snapshot
Table 39: Amgen Inc.: Financial Performance, FY 2022 and 2023
Table 40: Amgen Inc.: Product Portfolio
Table 41: Amgen Inc.: News/Key Developments, 2024
Table 42: AstraZeneca: Company Snapshot
Table 43: AstraZeneca: Financial Performance, FY 2022 and 2023
Table 44: AstraZeneca: Product Portfolio
Table 45: AstraZeneca: News/Key Developments, 2023-2024
Table 46: Bluebird Bio Inc.: Company Snapshot
Table 47: Bluebird Bio Inc.: Financial Performance, FY 2022 and 2023
Table 48: Bluebird Bio Inc.: Product Portfolio
Table 49: Bluebird Bio Inc.: News/Key Developments, 2020-2022
Table 50: Bristol-Myers Squibb Co.: Company Snapshot
Table 51: Bristol-Myers Squibb Co.: Financial Performance, FY 2022 and 2023
Table 52: Bristol-Myers Squibb Co.: Product Portfolio
Table 53: Bristol-Myers Squibb Co.: News/Key Developments, 2023-2024
Table 54: Cellectis S.A.: Company Snapshot
Table 55: Cellectis S.A.: Financial Performance, FY 2022 and 2023
Table 56: Cellectis S.A.: Product Portfolio
Table 57: Cellectis S.A.: News/Key Developments, 2023-2024
Table 58: Eureka Therapeutics Inc.: Company Snapshot
Table 59: Eureka Therapeutics Inc: Product Portfolio
Table 60: Eureka Therapeutics Inc.: News/Key Developments, 2023-2024
Table 61: Gilead Sciences Inc.: Company Snapshot
Table 62: Gilead Sciences Inc.: Financial Performance, FY 2022 and 2023
Table 63: Gilead Sciences Inc.: Product Portfolio
Table 64: Gilead Sciences Inc.: News/Key Developments, 2022-2024
Table 65: iCell Gene Therapeutics Inc.: Company Snapshot
Table 66: iCell Gene Therapeutics Inc: Product Portfolio
Table 67: iCell Gene Therapeutics Inc.: News/Key Developments, 2024
Table 68: Johnson & Johnson Services Inc.: Company Snapshot
Table 69: Johnson & Johnson Services Inc.: Financial Performance, FY 2022 and 2023
Table 70: Johnson & Johnson Services Inc.: Product Portfolio
Table 71: Johnson & Johnson Services Inc.: News/Key Developments, 2022-2024
Table 72: Les Laboratoires Servier: Company Snapshot
Table 73: Les Laboratoires Servier: Product Portfolio
Table 74: Les Laboratoires Servier: News/Key Developments, 2024
Table 75: Novartis AG: Company Snapshot
Table 76: Novartis AG: Financial Performance, FY 2022 and 2023
Table 77: Novartis AG: Product Portfolio
Table 78: Novartis AG: News/Key Developments, 2021-2024
Table 79: Pfizer Inc.: Company Snapshot
Table 80: Pfizer Inc.: Financial Performance, FY 2022 and 2023
Table 81: Pfizer Inc.: Product Portfolio
Table 82: Pfizer Inc.: News/Key Developments, 2023
Table 83: Protheragen Inc.: Company Snapshot
Table 84: Protheragen Inc.: Product Portfolio
List of Figures
Summary Figure: Global Market for CAR T-Cell Therapy, by Product, 2022-2029
Figure 1: Historical Development of CAR T-Cell Therapy, 1992-2017
Figure 2: Snapshot of the Market Dynamics for CAR T-Cell Therapy
Figure 3: Estimated New Cancer Cases, 2022, 2045 and 2050
Figure 4: Breakdown of CAR T-Cell Therapy Clinical Trials, by Status, January 2023
Figure 5: Breakdown of CAR T-Cell Therapy Clinical Trials, by Study Phase, January 2023
Figure 6: Breakdown of CAR T-Cell Therapy Clinical Trials, by Investigator Type, January 2023
Figure 7: Global CAR T-Cell Clinical Trial Activity, by Study Start Date and Phase, 2021-2024
Figure 8: Global Market Shares of CAR T-Cell Therapy, by Product, 2024
Figure 9: Global Market Shares for Yescarta, by Region, 2024
Figure 10: Global Market Shares for Kymriah, by Region, 2024
Figure 11: Global Market Shares for Tecartus, by Region, 2024
Figure 12: Global Market Shares for Abecma, by Region, 2024
Figure 13: Global Market Shares for Breyanzi, by Region, 2024
Figure 14: Global Market Shares for Carvykti, by Region, 2024
Figure 15: Global Market Shares of CAR T-Cells Therapy, by Indication, 2024
Figure 16: Global Market Shares of CAR T-Cell Therapy, by Region, 2024
Figure 17: Strategic Considerations
Figure 18: How a Strong ESG Proposition Benefits Businesses
Figure 19: AbbVie Inc.: Revenue Share, by Business Unit, FY 2023
Figure 20: AbbVie Inc.: Revenue Share, by Country/Region, FY 2023
Figure 21: Amgen Inc.: Revenue Share, by Business Unit, FY 2023
Figure 22: Amgen Inc.: Revenue Share, by Country/Region, FY 2023
Figure 23: AstraZeneca: Revenue Share, by Business Unit, FY 2023
Figure 24: AstraZeneca: Revenue Share, by Region/Country, FY 2023
Figure 25: Bristol Myers Squibb Co.: Revenue Share, by Business Unit, FY 2023
Figure 26: Bristol-Myers Squibb Co.: Revenue Share, by Country/Region, FY 2023
Figure 27: Gilead Sciences Inc.: Revenue Share, by Business Unit, FY 2023
Figure 28: Gilead Sciences Inc.: Revenue Share, by Country/Region, FY 2023
Figure 29: Johnson & Johnson Services Inc.: Revenue Share, by Business Unit, FY 2023
Figure 30: Johnson & Johnson Services Inc.: Revenue Share, by Country/Region, FY 2023
Figure 31: Novartis AG: Revenue Share, by Business Unit, FY 2023
Figure 32: Novartis AG: Revenue Share, by Country/Region, FY 2023
Figure 33: Pfizer Inc.: Revenue Share, by Business Unit, FY 2023
Figure 34: Pfizer Inc.: Revenue Share, by Country/Region, FY 2023