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Tumor Necrosis Factor Inhibitor Drugs - Global Strategic Business Report

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    Report

  • 66 Pages
  • May 2025
  • Region: Global
  • Global Industry Analysts, Inc
  • ID: 6070852
This comprehensive report provides an in-depth analysis of market trends, drivers, and forecasts, helping you make informed business decisions. The report includes the most recent global tariff developments and how they impact the Tumor Necrosis Factor Inhibitor Drugs market.

Tumor Necrosis Factor (TNF) Inhibitor Drugs Market Trends & Drivers Summarized

How Are TNF Inhibitor Drugs Transforming the Treatment of Autoimmune Diseases?

Tumor Necrosis Factor (TNF) inhibitor drugs have revolutionized the treatment of autoimmune and inflammatory diseases, including rheumatoid arthritis (RA), psoriasis, Crohn’s disease, ulcerative colitis, and ankylosing spondylitis. These biologic therapies work by targeting TNF-α, a cytokine that plays a key role in inflammation, thereby reducing disease activity and preventing long-term joint and tissue damage. TNF inhibitors such as infliximab, etanercept, adalimumab, golimumab, and certolizumab pegol have set a new standard in immunomodulatory therapy, significantly improving patient quality of life. However, challenges such as high treatment costs, the risk of infections due to immunosuppression, and the emergence of biosimilars are reshaping the competitive landscape. Additionally, the growing availability of Janus kinase (JAK) inhibitors and interleukin (IL) inhibitors is introducing new treatment alternatives, intensifying competition in the biologics market. As precision medicine advances, how will TNF inhibitors continue to evolve in the broader landscape of autoimmune disease management?

What Technological Innovations Are Advancing TNF Inhibitor Therapies?

Recent innovations in TNF inhibitor drug development focus on improving efficacy, patient adherence, and safety. Subcutaneous self-injector pens with extended half-life formulations are reducing dosing frequency, enhancing patient convenience. AI-driven drug discovery platforms are identifying next-generation TNF inhibitors with improved selectivity and fewer adverse effects. Personalized biologic therapy approaches, guided by genetic and biomarker profiling, are optimizing treatment selection based on individual patient responses. Additionally, the emergence of biosimilar TNF inhibitors is expanding treatment accessibility, reducing costs, and increasing competition among biologic drug manufacturers.

Why Is the Demand for TNF Inhibitor Drugs Increasing?

The rising prevalence of autoimmune diseases, increasing patient preference for targeted biologic therapies, and expanding regulatory approvals for new indications are driving demand for TNF inhibitors. The shift toward early intervention strategies in rheumatoid arthritis and inflammatory bowel disease (IBD) is further accelerating adoption. Additionally, the growing awareness of personalized medicine is encouraging physicians to integrate TNF inhibitors into tailored treatment regimens.

What Factors Are Driving the Growth of the TNF Inhibitor Drugs Market?

The market is expanding due to increasing investment in biologic drug development, rising adoption of biosimilars, growing demand for long-acting and self-administered formulations, and the continuous expansion of TNF inhibitors into new autoimmune disease indications. As the field of immunology advances, TNF inhibitors are expected to remain a cornerstone of biologic therapy while competing with emerging targeted therapies, offering patients more effective and personalized treatment options.

Report Scope

The report analyzes the Tumor Necrosis Factor Inhibitor Drugs market, presented in terms of market value (US$ Thousand). The analysis covers the key segments and geographic regions outlined below.

Segments: Distribution Channel (Hospital Pharmacy, Specialty Pharmacy, Online Pharmacy); Application (Rheumatoid Arthritis, Psoriasis, Psoriatic Arthritis, Ulcerative Colitis, Crohn`s Disease, Ankylosing Spondylitis, Juvenile Idiopathic Arthritis, Hidradenitis suppurativa, Others)

Geographic Regions/Countries: World; United States; Canada; Japan; China; Europe (France; Germany; Italy; United Kingdom; Spain; Russia; and Rest of Europe); Asia-Pacific (Australia; India; South Korea; and Rest of Asia-Pacific); Latin America (Argentina; Brazil; Mexico; and Rest of Latin America); Middle East (Iran; Israel; Saudi Arabia; United Arab Emirates; and Rest of Middle East); and Africa.

Why You Should Buy This Report:

  • Detailed Market Analysis: Access a thorough analysis of the Global Tumor Necrosis Factor Inhibitor Drugs Market, covering all major geographic regions and market segments.
  • Competitive Insights: Get an overview of the competitive landscape, including the market presence of major players across different geographies.
  • Future Trends and Drivers: Understand the key trends and drivers shaping the future of the Global Tumor Necrosis Factor Inhibitor Drugs Market.
  • Actionable Insights: Benefit from actionable insights that can help you identify new revenue opportunities and make strategic business decisions.

Key Questions Answered:

  • How is the Global Tumor Necrosis Factor Inhibitor Drugs Market expected to evolve by 2030?
  • What are the main drivers and restraints affecting the market?
  • Which market segments will grow the most over the forecast period?
  • How will market shares for different regions and segments change by 2030?
  • Who are the leading players in the market, and what are their prospects?

Report Features:

  • Comprehensive Market Data: Independent analysis of annual sales and market forecasts in US$ Million from 2024 to 2030.
  • In-Depth Regional Analysis: Detailed insights into key markets, including the U.S., China, Japan, Canada, Europe, Asia-Pacific, Latin America, Middle East, and Africa.
  • Company Profiles: Coverage of players such as AbbVie Inc., Ablynx (a Sanofi company), Amgen Inc., AryoGen Pharmed Co. Ltd., Boehringer Ingelheim GmbH and more.
  • Complimentary Updates: Receive free report updates for one year to keep you informed of the latest market developments.

Select Competitors (Total 36 Featured):

  • AbbVie Inc.
  • Ablynx (a Sanofi company)
  • Amgen Inc.
  • AryoGen Pharmed Co. Ltd.
  • Boehringer Ingelheim GmbH
  • Bristol-Myers Squibb Company
  • Cadila Healthcare Limited (Zydus Cadila)
  • Celltrion Healthcare Co. Ltd.
  • Eli Lilly and Company
  • EPIRUS Biopharmaceuticals Inc.
  • GlaxoSmithKline plc
  • HanAll Biopharma Co. Ltd.
  • Janssen Biotech, Inc. (a Johnson & Johnson company)
  • LG Life Sciences Ltd.
  • Merck & Co., Inc.
  • Momenta Pharmaceuticals (a Johnson & Johnson company)
  • Novartis International AG
  • Pfizer Inc.
  • Samsung Bioepis Co., Ltd.
  • Sanofi S.A.
  • Sandoz International GmbH (a Novartis division)
  • Teva Pharmaceutical Industries Ltd.

Tariff Impact Analysis: Key Insights for 2025

Global tariff negotiations across 180+ countries are reshaping supply chains, costs, and competitiveness. This report reflects the latest developments as of April 2025 and incorporates forward-looking insights into the market outlook.

The analysts continuously track trade developments worldwide, drawing insights from leading global economists and over 200 industry and policy institutions, including think tanks, trade organizations, and national economic advisory bodies. This intelligence is integrated into forecasting models to provide timely, data-driven analysis of emerging risks and opportunities.

What’s Included in This Edition:

  • Tariff-adjusted market forecasts by region and segment
  • Analysis of cost and supply chain implications by sourcing and trade exposure
  • Strategic insights into geographic shifts

Buyers receive a free July 2025 update with:

  • Finalized tariff impacts and new trade agreement effects
  • Updated projections reflecting global sourcing and cost shifts
  • Expanded country-specific coverage across the industry

Table of Contents

I. METHODOLOGYII. EXECUTIVE SUMMARY
1. MARKET OVERVIEW
  • Influencer Market Insights
  • Tariff Impact on Global Supply Chain Patterns
  • Tumor Necrosis Factor Inhibitor Drugs - Global Key Competitors Percentage Market Share in 2024 (E)
  • Competitive Market Presence - Strong/Active/Niche/Trivial for Players Worldwide in 2024 (E)
2. FOCUS ON SELECT PLAYERS
3. MARKET TRENDS & DRIVERS
  • Rising Prevalence of Autoimmune Conditions Drives Therapeutic Demand for TNF Inhibitors
  • Advancements in Biologics Improve Efficacy and Expand Prescribing Confidence
  • Accelerated Approval and Commercialization of Biosimilars Increases Market Competitiveness
  • Shift to Digital Distribution Channels Spurs Growth in Online Pharmacies for TNF Therapies
  • Adalimumab Maintains Market Leadership Due to Broad Indication Spectrum and Clinical Success
  • North America Retains Dominance Backed by High Diagnosis Rates and Reimbursement Support
  • Preference for Subcutaneous Injections Enhances Outpatient Treatment Adoption
  • Personalized Medicine and Companion Diagnostics Strengthen Patient-Therapy Alignment
  • Price Volatility and Net Cost Increases Pose Affordability Challenges in Key Markets
  • Expansion of Indications Broadens Patient Base for Existing TNF Therapies
  • Strategic Industry Alliances Support Pipeline Development and Global Reach
  • Steady Market Growth Forecast Reflects Sustained Long-Term Clinical Relevance
4. GLOBAL MARKET PERSPECTIVE
  • TABLE 1: World Tumor Necrosis Factor Inhibitor Drugs Market Analysis of Annual Sales in US$ Million for Years 2015 through 2030
  • TABLE 2: World Recent Past, Current & Future Analysis for Tumor Necrosis Factor Inhibitor Drugs by Geographic Region - USA, Canada, Japan, China, Europe, Asia-Pacific, Latin America, Middle East and Africa Markets - Independent Analysis of Annual Sales in US$ Million for Years 2024 through 2030 and % CAGR
  • TABLE 3: World Historic Review for Tumor Necrosis Factor Inhibitor Drugs by Geographic Region - USA, Canada, Japan, China, Europe, Asia-Pacific, Latin America, Middle East and Africa Markets - Independent Analysis of Annual Sales in US$ Million for Years 2015 through 2023 and % CAGR
  • TABLE 4: World 15-Year Perspective for Tumor Necrosis Factor Inhibitor Drugs by Geographic Region - Percentage Breakdown of Value Sales for USA, Canada, Japan, China, Europe, Asia-Pacific, Latin America, Middle East and Africa Markets for Years 2015, 2025 & 2030
  • TABLE 5: World Recent Past, Current & Future Analysis for Hospital Pharmacy by Geographic Region - USA, Canada, Japan, China, Europe, Asia-Pacific, Latin America, Middle East and Africa Markets - Independent Analysis of Annual Sales in US$ Million for Years 2024 through 2030 and % CAGR
  • TABLE 6: World Historic Review for Hospital Pharmacy by Geographic Region - USA, Canada, Japan, China, Europe, Asia-Pacific, Latin America, Middle East and Africa Markets - Independent Analysis of Annual Sales in US$ Million for Years 2015 through 2023 and % CAGR
  • TABLE 7: World 15-Year Perspective for Hospital Pharmacy by Geographic Region - Percentage Breakdown of Value Sales for USA, Canada, Japan, China, Europe, Asia-Pacific, Latin America, Middle East and Africa for Years 2015, 2025 & 2030
  • TABLE 8: World Recent Past, Current & Future Analysis for Specialty Pharmacy by Geographic Region - USA, Canada, Japan, China, Europe, Asia-Pacific, Latin America, Middle East and Africa Markets - Independent Analysis of Annual Sales in US$ Million for Years 2024 through 2030 and % CAGR
  • TABLE 9: World Historic Review for Specialty Pharmacy by Geographic Region - USA, Canada, Japan, China, Europe, Asia-Pacific, Latin America, Middle East and Africa Markets - Independent Analysis of Annual Sales in US$ Million for Years 2015 through 2023 and % CAGR
  • TABLE 10: World 15-Year Perspective for Specialty Pharmacy by Geographic Region - Percentage Breakdown of Value Sales for USA, Canada, Japan, China, Europe, Asia-Pacific, Latin America, Middle East and Africa for Years 2015, 2025 & 2030
  • TABLE 11: World Recent Past, Current & Future Analysis for Online Pharmacy by Geographic Region - USA, Canada, Japan, China, Europe, Asia-Pacific, Latin America, Middle East and Africa Markets - Independent Analysis of Annual Sales in US$ Million for Years 2024 through 2030 and % CAGR
  • TABLE 12: World Historic Review for Online Pharmacy by Geographic Region - USA, Canada, Japan, China, Europe, Asia-Pacific, Latin America, Middle East and Africa Markets - Independent Analysis of Annual Sales in US$ Million for Years 2015 through 2023 and % CAGR
  • TABLE 13: World 15-Year Perspective for Online Pharmacy by Geographic Region - Percentage Breakdown of Value Sales for USA, Canada, Japan, China, Europe, Asia-Pacific, Latin America, Middle East and Africa for Years 2015, 2025 & 2030
  • TABLE 14: World Recent Past, Current & Future Analysis for Juvenile Idiopathic Arthritis by Geographic Region - USA, Canada, Japan, China, Europe, Asia-Pacific, Latin America, Middle East and Africa Markets - Independent Analysis of Annual Sales in US$ Million for Years 2024 through 2030 and % CAGR
  • TABLE 15: World Historic Review for Juvenile Idiopathic Arthritis by Geographic Region - USA, Canada, Japan, China, Europe, Asia-Pacific, Latin America, Middle East and Africa Markets - Independent Analysis of Annual Sales in US$ Million for Years 2015 through 2023 and % CAGR
  • TABLE 16: World 15-Year Perspective for Juvenile Idiopathic Arthritis by Geographic Region - Percentage Breakdown of Value Sales for USA, Canada, Japan, China, Europe, Asia-Pacific, Latin America, Middle East and Africa for Years 2015, 2025 & 2030
  • TABLE 17: World Recent Past, Current & Future Analysis for Hidradenitis suppurativa by Geographic Region - USA, Canada, Japan, China, Europe, Asia-Pacific, Latin America, Middle East and Africa Markets - Independent Analysis of Annual Sales in US$ Million for Years 2024 through 2030 and % CAGR
  • TABLE 18: World Historic Review for Hidradenitis suppurativa by Geographic Region - USA, Canada, Japan, China, Europe, Asia-Pacific, Latin America, Middle East and Africa Markets - Independent Analysis of Annual Sales in US$ Million for Years 2015 through 2023 and % CAGR
  • TABLE 19: World 15-Year Perspective for Hidradenitis suppurativa by Geographic Region - Percentage Breakdown of Value Sales for USA, Canada, Japan, China, Europe, Asia-Pacific, Latin America, Middle East and Africa for Years 2015, 2025 & 2030
  • TABLE 20: World Recent Past, Current & Future Analysis for Others by Geographic Region - USA, Canada, Japan, China, Europe, Asia-Pacific, Latin America, Middle East and Africa Markets - Independent Analysis of Annual Sales in US$ Million for Years 2024 through 2030 and % CAGR
  • TABLE 21: World Historic Review for Others by Geographic Region - USA, Canada, Japan, China, Europe, Asia-Pacific, Latin America, Middle East and Africa Markets - Independent Analysis of Annual Sales in US$ Million for Years 2015 through 2023 and % CAGR
  • TABLE 22: World 15-Year Perspective for Others by Geographic Region - Percentage Breakdown of Value Sales for USA, Canada, Japan, China, Europe, Asia-Pacific, Latin America, Middle East and Africa for Years 2015, 2025 & 2030
  • TABLE 23: World Recent Past, Current & Future Analysis for Rheumatoid Arthritis by Geographic Region - USA, Canada, Japan, China, Europe, Asia-Pacific, Latin America, Middle East and Africa Markets - Independent Analysis of Annual Sales in US$ Million for Years 2024 through 2030 and % CAGR
  • TABLE 24: World Historic Review for Rheumatoid Arthritis by Geographic Region - USA, Canada, Japan, China, Europe, Asia-Pacific, Latin America, Middle East and Africa Markets - Independent Analysis of Annual Sales in US$ Million for Years 2015 through 2023 and % CAGR
  • TABLE 25: World 15-Year Perspective for Rheumatoid Arthritis by Geographic Region - Percentage Breakdown of Value Sales for USA, Canada, Japan, China, Europe, Asia-Pacific, Latin America, Middle East and Africa for Years 2015, 2025 & 2030
  • TABLE 26: World Recent Past, Current & Future Analysis for Psoriasis by Geographic Region - USA, Canada, Japan, China, Europe, Asia-Pacific, Latin America, Middle East and Africa Markets - Independent Analysis of Annual Sales in US$ Million for Years 2024 through 2030 and % CAGR
  • TABLE 27: World Historic Review for Psoriasis by Geographic Region - USA, Canada, Japan, China, Europe, Asia-Pacific, Latin America, Middle East and Africa Markets - Independent Analysis of Annual Sales in US$ Million for Years 2015 through 2023 and % CAGR
  • TABLE 28: World 15-Year Perspective for Psoriasis by Geographic Region - Percentage Breakdown of Value Sales for USA, Canada, Japan, China, Europe, Asia-Pacific, Latin America, Middle East and Africa for Years 2015, 2025 & 2030
  • TABLE 29: World Recent Past, Current & Future Analysis for Psoriatic Arthritis by Geographic Region - USA, Canada, Japan, China, Europe, Asia-Pacific, Latin America, Middle East and Africa Markets - Independent Analysis of Annual Sales in US$ Million for Years 2024 through 2030 and % CAGR
  • TABLE 30: World Historic Review for Psoriatic Arthritis by Geographic Region - USA, Canada, Japan, China, Europe, Asia-Pacific, Latin America, Middle East and Africa Markets - Independent Analysis of Annual Sales in US$ Million for Years 2015 through 2023 and % CAGR
  • TABLE 31: World 15-Year Perspective for Psoriatic Arthritis by Geographic Region - Percentage Breakdown of Value Sales for USA, Canada, Japan, China, Europe, Asia-Pacific, Latin America, Middle East and Africa for Years 2015, 2025 & 2030
  • TABLE 32: World Recent Past, Current & Future Analysis for Ulcerative Colitis by Geographic Region - USA, Canada, Japan, China, Europe, Asia-Pacific, Latin America, Middle East and Africa Markets - Independent Analysis of Annual Sales in US$ Million for Years 2024 through 2030 and % CAGR
  • TABLE 33: World Historic Review for Ulcerative Colitis by Geographic Region - USA, Canada, Japan, China, Europe, Asia-Pacific, Latin America, Middle East and Africa Markets - Independent Analysis of Annual Sales in US$ Million for Years 2015 through 2023 and % CAGR
  • TABLE 34: World 15-Year Perspective for Ulcerative Colitis by Geographic Region - Percentage Breakdown of Value Sales for USA, Canada, Japan, China, Europe, Asia-Pacific, Latin America, Middle East and Africa for Years 2015, 2025 & 2030
  • TABLE 35: World Recent Past, Current & Future Analysis for Crohn`s Disease by Geographic Region - USA, Canada, Japan, China, Europe, Asia-Pacific, Latin America, Middle East and Africa Markets - Independent Analysis of Annual Sales in US$ Million for Years 2024 through 2030 and % CAGR
  • TABLE 36: World Historic Review for Crohn`s Disease by Geographic Region - USA, Canada, Japan, China, Europe, Asia-Pacific, Latin America, Middle East and Africa Markets - Independent Analysis of Annual Sales in US$ Million for Years 2015 through 2023 and % CAGR
  • TABLE 37: World 15-Year Perspective for Crohn`s Disease by Geographic Region - Percentage Breakdown of Value Sales for USA, Canada, Japan, China, Europe, Asia-Pacific, Latin America, Middle East and Africa for Years 2015, 2025 & 2030
  • TABLE 38: World Recent Past, Current & Future Analysis for Ankylosing Spondylitis by Geographic Region - USA, Canada, Japan, China, Europe, Asia-Pacific, Latin America, Middle East and Africa Markets - Independent Analysis of Annual Sales in US$ Million for Years 2024 through 2030 and % CAGR
  • TABLE 39: World Historic Review for Ankylosing Spondylitis by Geographic Region - USA, Canada, Japan, China, Europe, Asia-Pacific, Latin America, Middle East and Africa Markets - Independent Analysis of Annual Sales in US$ Million for Years 2015 through 2023 and % CAGR
  • TABLE 40: World 15-Year Perspective for Ankylosing Spondylitis by Geographic Region - Percentage Breakdown of Value Sales for USA, Canada, Japan, China, Europe, Asia-Pacific, Latin America, Middle East and Africa for Years 2015, 2025 & 2030
III. MARKET ANALYSIS
  • UNITED STATES
  • Tumor Necrosis Factor Inhibitor Drugs Market Presence - Strong/Active/Niche/Trivial - Key Competitors in the United States for 2025 (E)
  • CANADA
  • JAPAN
  • Tumor Necrosis Factor Inhibitor Drugs Market Presence - Strong/Active/Niche/Trivial - Key Competitors in Japan for 2025 (E)
  • CHINA
  • Tumor Necrosis Factor Inhibitor Drugs Market Presence - Strong/Active/Niche/Trivial - Key Competitors in China for 2025 (E)
  • EUROPE
  • Tumor Necrosis Factor Inhibitor Drugs Market Presence - Strong/Active/Niche/Trivial - Key Competitors in Europe for 2025 (E)
  • FRANCE
  • Tumor Necrosis Factor Inhibitor Drugs Market Presence - Strong/Active/Niche/Trivial - Key Competitors in France for 2025 (E)
  • GERMANY
  • Tumor Necrosis Factor Inhibitor Drugs Market Presence - Strong/Active/Niche/Trivial - Key Competitors in Germany for 2025 (E)
  • ITALY
  • UNITED KINGDOM
  • Tumor Necrosis Factor Inhibitor Drugs Market Presence - Strong/Active/Niche/Trivial - Key Competitors in the United Kingdom for 2025 (E)
  • SPAIN
  • RUSSIA
  • REST OF EUROPE
  • ASIA-PACIFIC
  • Tumor Necrosis Factor Inhibitor Drugs Market Presence - Strong/Active/Niche/Trivial - Key Competitors in Asia-Pacific for 2025 (E)
  • AUSTRALIA
  • Tumor Necrosis Factor Inhibitor Drugs Market Presence - Strong/Active/Niche/Trivial - Key Competitors in Australia for 2025 (E)
  • INDIA
  • Tumor Necrosis Factor Inhibitor Drugs Market Presence - Strong/Active/Niche/Trivial - Key Competitors in India for 2025 (E)
  • SOUTH KOREA
  • REST OF ASIA-PACIFIC
  • LATIN AMERICA
  • Tumor Necrosis Factor Inhibitor Drugs Market Presence - Strong/Active/Niche/Trivial - Key Competitors in Latin America for 2025 (E)
  • ARGENTINA
  • BRAZIL
  • MEXICO
  • REST OF LATIN AMERICA
  • MIDDLE EAST
  • Tumor Necrosis Factor Inhibitor Drugs Market Presence - Strong/Active/Niche/Trivial - Key Competitors in Middle East for 2025 (E)
  • IRAN
  • ISRAEL
  • SAUDI ARABIA
  • UNITED ARAB EMIRATES
  • REST OF MIDDLE EAST
  • AFRICA
  • Tumor Necrosis Factor Inhibitor Drugs Market Presence - Strong/Active/Niche/Trivial - Key Competitors in Africa for 2025 (E)
IV. COMPETITION

Companies Mentioned (Partial List)

A selection of companies mentioned in this report includes, but is not limited to:

  • AbbVie Inc.
  • Ablynx (a Sanofi company)
  • Amgen Inc.
  • AryoGen Pharmed Co. Ltd.
  • Boehringer Ingelheim GmbH
  • Bristol-Myers Squibb Company
  • Cadila Healthcare Limited (Zydus Cadila)
  • Celltrion Healthcare Co. Ltd.
  • Eli Lilly and Company
  • EPIRUS Biopharmaceuticals Inc.
  • GlaxoSmithKline plc
  • HanAll Biopharma Co. Ltd.
  • Janssen Biotech, Inc. (a Johnson & Johnson company)
  • LG Life Sciences Ltd.
  • Merck & Co., Inc.
  • Momenta Pharmaceuticals (a Johnson & Johnson company)
  • Novartis International AG
  • Pfizer Inc.
  • Samsung Bioepis Co., Ltd.
  • Sanofi S.A.
  • Sandoz International GmbH (a Novartis division)
  • Teva Pharmaceutical Industries Ltd.