The growth in the forecast period can be attributed to increasing research into genetic disorders, rising use of gene therapy, rising demand for biologic therapies, a growing number of healthcare programs, and a growing number of patients diagnosed with chronic obstructive pulmonary disease. Major trends in the forecast period include technological advancements, advancement in biologics and biosimilars, integration of artificial intelligence, adoption of electronic health records, and protein-based therapies.
The increasing prevalence of alpha-1 antitrypsin deficiency (AATD) is anticipated to drive the growth of the aralast and aralast NP market. AATD is a genetic disorder caused by low levels or dysfunction of the alpha-1 antitrypsin protein, leading to lung and liver damage. The rising prevalence of AATD is attributed to factors such as enhanced awareness, improved diagnostic techniques, and better recognition of the condition in individuals with respiratory or liver diseases. Aralast and Aralast NP are essential in treating AATD by providing supplemental alpha-1 antitrypsin protein to help protect the lungs and liver. For example, in October 2024, the National Library of Medicine reported an increase in hospital admissions for AATD in Spain in 2022, with men accounting for 58.21% of the cases. Men were also more likely to be readmitted, and the in-hospital death rate for men was higher than for women. This growing prevalence of AATD is fueling the demand for aralast and aralast NP.
The growth of the aralast and aralast NP market is driven by an increase in research and development (R&D) activities. R&D efforts focus on innovating and improving products, processes, and technologies through scientific research and experimentation. The rising demand for technological advancements, competition, and the need to tackle global challenges such as healthcare and sustainability are driving R&D. These efforts are vital for developing optimized therapies, enhancing the efficacy, safety, and patient outcomes of treatments for AATD. For instance, the Department of Health and Social Care in the UK reported in July 2024 that the business enterprise sector invested £9 billion ($11.4 billion) in pharmaceutical R&D in 2022, which made up 0.36% of the UK's GDP. Pharmaceutical R&D was the largest area for business-led research investment in the country. Consequently, the rise in R&D activities is supporting the growth of the aralast and aralast NP market.
A significant trend in the market is the growing focus on strategic investments in biopharmaceutical R&D labs. These specialized facilities are crucial in the discovery, development, and testing of biologic drugs, including treatments for diseases such as AATD. In September 2023, Takeda Pharmaceutical Company announced a substantial investment in a new, environmentally sustainable biopharmaceutical R&D facility in Vienna's Seestadt Aspern neighborhood. The facility, which will employ around 250 researchers by 2026, will focus on developing innovative therapies for diseases with unmet needs. This lab, designed with cutting-edge technologies and environmental standards, underscores Takeda's commitment to advancing biopharmaceutical research and development, driving innovation in the AATD treatment market.
The key company operating in the aralast, aralast Np market is Takeda Pharmaceutical Company Limited
North America was the largest region in the aralast, aralast NP market in 2024. Asia-Pacific is expected to be the fastest-growing region in the forecast period. The regions covered in aralast, aralast NP report are Asia-Pacific, Western Europe, Eastern Europe, North America, South America, Middle East and Africa.The countries covered in the aralast, aralast Np market report are Australia, Brazil, China, France, Germany, India, Indonesia, Japan, Russia, South Korea, UK, USA, Canada, Italy, Spain.
Aralast and Aralast NP are brand names for alpha-1 proteinase inhibitor (A1PI), a medication used to treat individuals with Alpha-1 Antitrypsin Deficiency (AATD). AATD is a genetic condition that can result in emphysema or chronic obstructive pulmonary disease (COPD). Aralast delivers alpha-1 antitrypsin (AAT), a protein that safeguards lung tissue from damage caused by neutrophil elastase, an enzyme that can break down lung tissue if left unregulated.
Note that the outlook for this market is being affected by rapid changes in trade relations and tariffs globally. The report will be updated prior to delivery to reflect the latest status, including revised forecasts and quantified impact analysis. The report’s Recommendations and Conclusions sections will be updated to give strategies for entities dealing with the fast-moving international environment.
The primary indications for aralast and aralast NP include Alpha-1 Antitrypsin Deficiency (AATD), chronic obstructive pulmonary disease (COPD), and liver disease. AATD is a genetic disorder characterized by low levels or dysfunction of the alpha-1 antitrypsin protein, which leads to lung and liver damage. The medication is distributed through various channels, such as direct sales and wholesale distributors, and is used in hospitals, specialty clinics, and pharmacies.
The aralast, aralast Np market consists of sales of alpha-1 proteinase inhibitor products, medical devices for administration, IV administration kits, alpha-1 antitrypsin testing kits and oral supplements for lung health. Values in this market are ‘factory gate’ values, that is the value of goods sold by the manufacturers or creators of the goods, whether to other entities (including downstream manufacturers, wholesalers, distributors and retailers) or directly to end customers. The value of goods in this market includes related services sold by the creators of the goods.
The market value is defined as the revenues that enterprises gain from the sale of goods and/or services within the specified market and geography through sales, grants, or donations in terms of the currency (in USD, unless otherwise specified).
The revenues for a specified geography are consumption values that are revenues generated by organizations in the specified geography within the market, irrespective of where they are produced. It does not include revenues from resales along the supply chain, either further along the supply chain or as part of other products.
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Table of Contents
Executive Summary
Aralast, Aralast Np Global Market Report 2025 provides strategists, marketers and senior management with the critical information they need to assess the market.This report focuses on aralast, aralast np market which is experiencing strong growth. The report gives a guide to the trends which will be shaping the market over the next ten years and beyond.
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Description
Where is the largest and fastest growing market for aralast, aralast np ? How does the market relate to the overall economy, demography and other similar markets? What forces will shape the market going forward? The aralast, aralast np market global report answers all these questions and many more.The report covers market characteristics, size and growth, segmentation, regional and country breakdowns, competitive landscape, market shares, trends and strategies for this market. It traces the market’s historic and forecast market growth by geography.
- The market characteristics section of the report defines and explains the market.
- The market size section gives the market size ($b) covering both the historic growth of the market, and forecasting its development.
- The forecasts are made after considering the major factors currently impacting the market. These include:
- The forecasts are made after considering the major factors currently impacting the market. These include the Russia-Ukraine war, rising inflation, higher interest rates, and the legacy of the COVID-19 pandemic.
- Market segmentations break down the market into sub markets.
- The regional and country breakdowns section gives an analysis of the market in each geography and the size of the market by geography and compares their historic and forecast growth. It covers the growth trajectory of COVID-19 for all regions, key developed countries and major emerging markets.
- The competitive landscape chapter gives a description of the competitive nature of the market, market shares, and a description of the leading companies. Key financial deals which have shaped the market in recent years are identified.
- The trends and strategies section analyses the shape of the market as it emerges from the crisis and suggests how companies can grow as the market recovers.
Scope
Markets Covered:
1) By Indication: Alpha-1 Antitrypsin Deficiency (AATD); Chronic Obstructive Pulmonary Disease (COPD); Liver Disease2) By Distribution Channel: Direct Sales; Wholesale Distributors
3) By End User: Hospitals; Specialty Clinics; Pharmacies
Key Companies Profiled: Takeda Pharmaceutical Company Limited
Countries: Australia, India, China, South Korea, Japan, UK, France, Germany, USA, Canada
Regions: Asia-Pacific; Western Europe; Eastern Europe; North America; South America; Middle East; Africa
Time Series: Five years historic and ten years forecast.
Data: Ratios of market size and growth to related markets, GDP proportions, expenditure per capita.
Data Segmentation: Country and regional historic and forecast data, market share of competitors, market segments.
Sourcing and Referencing: Data and analysis throughout the report is sourced using end notes.
Delivery Format: PDF, Word and Excel Data Dashboard.
Companies Mentioned
- Takeda Pharmaceutical Company Limited