Medical Nitrous Oxide Global Market Report 2025

The medical nitrous oxide market size has grown rapidly in recent years. It will grow from $2.15 billion in 2024 to $2.37 billion in 2025 at a compound annual growth rate (CAGR) of 10.3%. The growth during the historic period can be attributed to the rise in surgical procedures, an increase in dental treatments, greater awareness of pain management options, the expansion of medical facilities, and the growth of emergency medical services.

The medical nitrous oxide market size is expected to see rapid growth in the next few years. It will grow to $3.47 billion in 2029 at a compound annual growth rate (CAGR) of 10.2%. The growth in the forecast period can be attributed to the aging global population, an increasing number of surgical procedures, a growing preference for non-invasive pain management, the expansion of home healthcare services, and the rising adoption of nitrous oxide in dental procedures. Key trends include advancements in anesthesia techniques, technological innovations in gas delivery systems, greater integration into dental practices, the development of new medical applications, and positive clinical research outcomes.

The increasing demand for pain management is driving the growth of the medical nitrous oxide market. Pain management focuses on alleviating pain through medications, therapies, and procedures, with demand rising due to factors such as the growing prevalence of chronic pain, aging populations, and advancements in treatment technologies. Medical nitrous oxide is widely used for pain management due to its rapid and effective analgesic properties, inducing mild sedation and euphoria while minimizing side effects and ensuring quick recovery. This makes it an ideal option for minor surgical procedures, dental work, and emergency pain relief. For instance, in November 2024, the Centers for Disease Control and Prevention (CDC) reported that in 2023, 24.3% of U.S. adults experienced chronic pain, with 8.5% having high-impact chronic pain that frequently limited daily activities, compared to 20.9% in 2021, when 6.9% had high-impact chronic pain. The increasing prevalence of chronic pain is thus fueling the growth of the medical nitrous oxide market.

Leading companies in the medical nitrous oxide market are focusing on technological advancements, such as innovative drug delivery systems, to enhance the safety, precision, and efficiency of nitrous oxide administration. Advanced drug delivery systems are designed to precisely administer therapeutic gases or drugs, improving efficacy, safety, and patient compliance. For example, in December 2023, Mallinckrodt plc, an Ireland-based pharmaceutical company, received US FDA clearance for its INOmax EVOLVE DS delivery system, which administers INOmax (nitric oxide) gas for inhalation. This system features an advanced injector module that ensures precise, synchronized dosing with specific ventilators and respiratory devices, maintaining consistent NO concentration throughout the breath cycle.

In July 2022, BPR Medical Limited, a UK-based medical equipment manufacturing company, partnered with Medclair AB to introduce mobile conversion technology that captures and converts 99% of nitrous oxide emissions into nitrogen and oxygen. This innovation supports NHS net-zero goals, improves healthcare workplace conditions, and ensures the safe use of inhaled analgesia. Medclair AB, a Sweden-based research and development company, specializes in the measurement, collection, and destruction of nitrous oxide emissions, further contributing to the market's environmental sustainability.

Major players in the medical nitrous oxide market are Linde plc, Air Liquide, KVK Corporation, Air Products and Chemicals Inc., Taiyo Nippon Sanso Corporation, American Welding & Gas Inc., Messer SE & Co. KGaA, Gulf Cryo, Norco Inc., Ellenbarrie Industrial Gases Ltd., Earlbeck Gases & Technology, CalOx Inc., Oxygen & Argon Works Ltd., Chengdu Taiyu Industrial Gases Co. Ltd., Southern Gas Limited, Praxair Technology Inc., Satramdas Gases Pvt. Ltd., BOC Healthcare, Carbide and Chemicals, SOL SpA, nexAir LLC, Steelman Gases Pvt. Ltd., Jiangsu Huazhong Gas Co. Ltd., and Vinayak Air Products Private Limited.

North America was the largest region in the medical nitrous oxide market in 2024. Asia-Pacific is expected to be the fastest-growing region in the forecast period. The regions covered in medical nitrous oxide report are Asia-Pacific, Western Europe, Eastern Europe, North America, South America, Middle East and Africa.

The countries covered in the medical nitrous oxide market report are Australia, Brazil, China, France, Germany, India, Indonesia, Japan, Russia, South Korea, UK, USA, Canada, Italy, Spain.

Medical nitrous oxide is a colorless, non-flammable gas used in healthcare for anesthesia, pain relief, and surgical procedures. Commonly known as laughing gas, it is widely utilized in dentistry, surgery, and emergency care to help reduce pain and anxiety.

The primary product types of medical nitrous oxide are gaseous and liquid states. In its gaseous state, medical nitrous oxide serves as a colorless, non-flammable anesthetic gas used for pain relief and sedation in medical and dental procedures. It is classified by purity levels into medium grade (98%-99%), A-Z grade (99.9%), and low grade (below 98%). Based on its application, medical nitrous oxide is used in cryosurgery, surgical insufflation, and anesthesia for pain relief. It is utilized by various end users, including dental clinics, emergency medical services, hospitals, research labs, veterinary clinics, and the food industry.

The medical nitrous oxide market research report is one of a series of new reports that provides medical nitrous oxide market statistics, including the medical nitrous oxide industry global market size, regional shares, competitors with the medical nitrous oxide market share, detailed medical nitrous oxide market segments, market trends, and opportunities, and any further data you may need to thrive in the medical nitrous oxide industry. This medical nitrous oxide market research report delivers a complete perspective of everything you need, with an in-depth analysis of the current and future scenarios of the industry.

The medical nitrous oxide market consists of sales of pure medical nitrous oxide (N₂O), nitrous oxide-oxygen mixture, and pre-mixed nitrous oxide for medical use. Values in this market are ‘factory gate’ values, that is, the value of goods sold by the manufacturers or creators of the goods, whether to other entities (including downstream manufacturers, wholesalers, distributors, and retailers) or directly to end customers. The value of goods in this market includes related services sold by the creators of the goods.

The market value is defined as the revenues that enterprises gain from the sale of goods and/or services within the specified market and geography through sales, grants, or donations in terms of the currency (in USD unless otherwise specified).

The revenues for a specified geography are consumption values and are revenues generated by organizations in the specified geography within the market, irrespective of where they are produced. It does not include revenues from resales along the supply chain, either further along the supply chain or as part of other products.

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