Granulomatosis With Polyangiitis Treatment Global Market Report 2025

The granulomatosis with polyangiitis treatment market size has grown strongly in recent years. It will grow from $2.36 billion in 2024 to $2.56 billion in 2025 at a compound annual growth rate (CAGR) of 8.2%. The growth during the historic period can be attributed to the increasing demand for drugs, the rising number of clinical trials, the growing need for effective treatment, the heightened focus on personalized medicine, and higher diagnosis rates of the disorder.

The granulomatosis with polyangiitis treatment market size is expected to see strong growth in the next few years. It will grow to $3.47 billion in 2029 at a compound annual growth rate (CAGR) of 7.9%. The growth during the forecast period can be attributed to the rising prevalence of autoimmune diseases, the increasing occurrence of granulomatosis, the growing incidences of polyangiitis, and the surge in immunological disorders. Key trends in the forecast period include advancements in drug development, progress in healthcare, improvements in diagnostic techniques, innovations in treatment options, and the development of biologics and biosimilars.

The growing prevalence of autoimmune diseases is expected to drive the expansion of the granulomatosis with polyangiitis treatment market. Autoimmune diseases arise when the body's immune system mistakenly targets healthy cells and tissues, causing inflammation and damage across various organs. This increasing prevalence is linked to environmental triggers such as infections, chemicals, pollutants, and lifestyle changes. Granulomatosis with polyangiitis treatment plays a crucial role in managing autoimmune diseases by using immunosuppressive therapies such as corticosteroids and cyclophosphamide, which help control inflammation and prevent organ damage. Early intervention and personalized treatment are essential for managing other autoimmune conditions with similar mechanisms. For example, according to a report published in June 2023 by the Office for National Statistics, a UK-based government department, the global population affected by multiple sclerosis (MS), an autoimmune disease, increased from 2.8 million in 2022 to 2.9 million in 2023. As a result, the rising prevalence of autoimmune diseases is fueling the growth of the granulomatosis with polyangiitis treatment market.

Leading companies in the granulomatosis with polyangiitis treatment market are emphasizing the development of innovative products, such as oral corticosteroids, to provide more effective treatment options that improve disease management while reducing the long-term side effects of steroid use. Oral corticosteroids help alleviate inflammation and suppress the immune system and are widely used for allergies, autoimmune diseases, and inflammatory disorders. For instance, in October 2024, AstraZeneca plc, a UK-based pharmaceutical company, announced the approval of Fasenra (bevacizumab) in the European Union as an add-on treatment for adult patients with relapsing or refractory eosinophilic granulomatosis with polyangiitis (EGPA). This approval followed positive findings from the MANDARA Phase III trial, which demonstrated Fasenra’s effectiveness in achieving remission and decreasing dependency on oral corticosteroids in EGPA patients.

In October 2022, Amgen Inc., a US-based biotechnology company, acquired ChemoCentryx Inc. for $3.7 billion. This acquisition aims to bolster Amgen's inflammation and nephrology portfolio by broadening the market reach of Tavneos (avacopan) and enhancing its presence in autoimmune and rare disease treatments. ChemoCentryx Inc. is a US-based company specializing in treatments for granulomatosis with polyangiitis and other inflammatory diseases.

Major players in the granulomatosis with polyangiitis treatment market are Pfizer Inc., F. Hoffmann-La Roche Ltd., Merck & Co. Inc., Sanofi S.A., AstraZeneca plc, GlaxoSmithKline plc, Eli Lilly and Company, Gilead Sciences Inc., Amgen Inc., Teva Pharmaceutical Industries Ltd., Otsuka Pharmaceutical Co. Ltd., Regeneron Pharmaceuticals Inc., Astellas Pharma Inc., Vertex Pharmaceuticals Incorporated, Genentech Inc., Incyte Corporation, Alnylam Pharmaceuticals Inc., Ionis Pharmaceuticals Inc., ChemoCentryx Inc., Medac Pharma Inc., InflaRx GmbH.

North America was the largest region in the granulomatosis with polyangiitis treatment market in 2024. The regions covered in granulomatosis with polyangiitis treatment report are Asia-Pacific, Western Europe, Eastern Europe, North America, South America, Middle East and Africa.

The countries covered in the granulomatosis with polyangiitis treatment market report are Australia, Brazil, China, France, Germany, India, Indonesia, Japan, Russia, South Korea, UK, USA, Canada, Italy, Spain.

Granulomatosis with Polyangiitis (GPA) treatment includes medications aimed at controlling inflammation, suppressing the immune system, and preventing organ damage. GPA is a rare autoimmune disease that causes inflammation in small to medium-sized blood vessels, leading to restricted blood flow and tissue damage, particularly affecting the respiratory tract and kidneys. The primary treatment approach involves immunosuppressive therapies, including corticosteroids and biologics, to reduce inflammation and protect organ function.

The key drug categories for treating granulomatosis with polyangiitis include steroids, immunosuppressants, and others. Steroids are anti-inflammatory medications that help decrease swelling and suppress immune activity. In GPA management, they are commonly used alongside other drugs to control symptoms. The treatment approaches involve immunosuppressants and corticosteroids, administered through various routes such as oral and intravenous. These medications are distributed through hospital pharmacies, retail pharmacies, and online pharmacies and are utilized by different end users, including hospitals, home care, specialty clinics, and others.

The granulomatosis with polyangiitis treatment market research report is one of a series of new reports that provides granulomatosis with polyangiitis treatment market statistics, including the granulomatosis with polyangiitis treatment industry global market size, regional shares, competitors with the granulomatosis with polyangiitis treatment market share, detailed granulomatosis with polyangiitis treatment market segments, market trends, and opportunities, and any further data you may need to thrive in the granulomatosis with polyangiitis treatment industry. This granulomatosis with polyangiitis treatment market research report delivers a complete perspective of everything you need, with an in-depth analysis of the current and future scenarios of the industry.

The granulomatosis with polyangiitis treatment market includes sales of symptomatic treatment, monoclonal antibodies, and plasmapheresis. The market value includes the value of related goods sold by the service provider or included within the service offering. Only goods and services traded between entities or sold to end consumers are included.

The market value is defined as the revenues that enterprises gain from the sale of goods and/or services within the specified market and geography through sales, grants, or donations in terms of the currency (in USD, unless otherwise specified).

The revenues for a specified geography are consumption values that are revenues generated by organizations in the specified geography within the market, irrespective of where they are produced. It does not include revenues from resales along the supply chain, either further along the supply chain or as part of other products.

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