Radioligand Therapy - Global Strategic Business Report

The global market for Radioligand Therapy was valued at US$10.0 Billion in 2024 and is projected to reach US$12.0 Billion by 2030, growing at a CAGR of 3.0% from 2024 to 2030. This comprehensive report provides an in-depth analysis of market trends, drivers, and forecasts, helping you make informed business decisions. The report includes the most recent global tariff developments and how they impact the Radioligand Therapy market.

Global 'Radioligand Therapy' Market - Key Trends & Drivers Summarized

Is Radioligand Therapy Redefining Cancer Treatment Paradigms?

Radioligand therapy (RLT) is gaining recognition as a breakthrough approach in oncology, offering a targeted and minimally invasive alternative to conventional cancer therapies. By binding radioactive isotopes to ligands that specifically target tumor cells, RLT delivers radiation directly to cancerous tissues while sparing healthy ones. This mechanism provides precise cytotoxicity with fewer systemic side effects, positioning RLT as a game-changer in treating metastatic and treatment-resistant cancers. Approved therapies like Lutathera (for neuroendocrine tumors) and Pluvicto (for metastatic prostate cancer) have demonstrated significant survival benefits and quality-of-life improvements. The growing understanding of tumor biomarkers and receptor profiles is enabling the development of new radioligands targeting a wider range of malignancies. As precision medicine becomes a clinical imperative, radioligand therapy is transitioning from a niche option to a core component of advanced oncology regimens.

How Are Innovations in Isotope and Ligand Development Expanding RLT Potential?

Advances in radiopharmaceutical engineering are rapidly enhancing the safety, efficacy, and reach of radioligand therapies. Innovations in chelator chemistry are improving the stability and binding affinity of isotopes like Lutetium-177, Actinium-225, and Yttrium-90. Parallel progress in peptide and antibody engineering is allowing for better tumor selectivity and longer circulatory half-lives. Researchers are now developing dual-targeting ligands and theranostic pairs that can be used for both imaging and therapy, facilitating real-time treatment monitoring and dose optimization. New radionuclides are also being introduced to overcome limitations of penetration depth and radiation range, making RLT effective for both small and deep-seated tumors. These innovations are helping to expand radioligand applications to previously untreatable cancers and improving outcomes in resistant tumor profiles. The evolving toolkit of isotopes and ligands is setting the stage for broader RLT adoption and personalization.

Can Clinical Infrastructure and Reimbursement Policies Keep Pace With Growing RLT Demand?

While radioligand therapy's clinical value is clear, its expansion is challenged by infrastructure readiness and regulatory pathways. RLT requires specialized facilities for radiopharmaceutical production, safe handling, and patient administration. Limited access to isotopes, especially alpha emitters, remains a supply chain hurdle in many regions. Moreover, the integration of RLT into oncology workflows demands collaboration between nuclear medicine, radiology, and oncology departments, necessitating cross-disciplinary training and protocol development. Reimbursement also remains inconsistent, with coverage often limited to approved indications or specific geographic regions. However, global health authorities are increasingly recognizing the cost-effectiveness of RLT in advanced cancer stages, leading to improved funding and policy support. Public-private partnerships are helping expand isotope supply and treatment infrastructure. As awareness grows and regulatory harmonization improves, logistical barriers are expected to diminish, unlocking wider RLT access.

What’s Powering The Radioligand Therapy Market’s Accelerated Growth?

The growth in the radioligand therapy market is driven by several factors rooted in technological development, oncological needs, and healthcare policy evolution. Technologically, the emergence of more stable isotopes, optimized ligands, and theranostic models is increasing clinical success rates and broadening applications. End-use trends highlight a rising incidence of late-stage and resistant cancers, where RLT offers a new line of hope. Pharmaceutical companies are aggressively investing in RLT pipelines, and M&A activity in the nuclear medicine space is fostering innovation. Healthcare systems are increasingly prioritizing personalized and value-based care, making RLT a strategically aligned option. Patient demand for minimally invasive, high-efficacy treatments is further accelerating market uptake. Global regulatory bodies are also streamlining approval pathways, with fast-track designations and funding incentives bolstering new development. Together, these factors are propelling RLT into the mainstream of cancer care.

Report Scope

The report analyzes the Radioligand Therapy market, presented in terms of market value (US$ Thousand). The analysis covers the key segments and geographic regions outlined below.

Segments: Indication (Prostate Cancer, Neuroendocrine Tumors, Breast Cancer, Other Indications); Isotope (Fluorine-18, Gallium-68, Lutetium-177, Other Isotopes); End-Use (Hospitals & Clinics, Diagnostic Centers, Other End-Uses).

Geographic Regions/Countries: World; United States; Canada; Japan; China; Europe (France; Germany; Italy; United Kingdom; Spain; Russia; and Rest of Europe); Asia-Pacific (Australia; India; South Korea; and Rest of Asia-Pacific); Latin America (Argentina; Brazil; Mexico; and Rest of Latin America); Middle East (Iran; Israel; Saudi Arabia; United Arab Emirates; and Rest of Middle East); and Africa.

Key Insights:

• Market Growth: Understand the significant growth trajectory of the Prostate Cancer Indication segment, which is expected to reach US$5.1 Billion by 2030 with a CAGR of a 2.5%. The Neuroendocrine Tumors Indication segment is also set to grow at 2.5% CAGR over the analysis period.
• Regional Analysis: Gain insights into the U.S. market, valued at $2.7 Billion in 2024, and China, forecasted to grow at an impressive 5.6% CAGR to reach $2.3 Billion by 2030. Discover growth trends in other key regions, including Japan, Canada, Germany, and the Asia-Pacific.

Why You Should Buy This Report:

• Detailed Market Analysis: Access a thorough analysis of the Global Radioligand Therapy Market, covering all major geographic regions and market segments.
• Competitive Insights: Get an overview of the competitive landscape, including the market presence of major players across different geographies.
• Future Trends and Drivers: Understand the key trends and drivers shaping the future of the Global Radioligand Therapy Market.
• Actionable Insights: Benefit from actionable insights that can help you identify new revenue opportunities and make strategic business decisions.

Key Questions Answered:

• How is the Global Radioligand Therapy Market expected to evolve by 2030?
• What are the main drivers and restraints affecting the market?
• Which market segments will grow the most over the forecast period?
• How will market shares for different regions and segments change by 2030?
• Who are the leading players in the market, and what are their prospects?

Report Features:

• Comprehensive Market Data: Independent analysis of annual sales and market forecasts in US$ Million from 2024 to 2030.
• In-Depth Regional Analysis: Detailed insights into key markets, including the U.S., China, Japan, Canada, Europe, Asia-Pacific, Latin America, Middle East, and Africa.
• Company Profiles: Coverage of players such as Accuray Incorporated, Advanced Accelerator Applications, ARTBIO, AstraZeneca, Bayer AG and more.
• Complimentary Updates: Receive free report updates for one year to keep you informed of the latest market developments.

Some of the 42 companies featured in this Radioligand Therapy market report include:

• Accuray Incorporated
• Advanced Accelerator Applications
• ARTBIO
• AstraZeneca
• Bayer AG
• Curium Pharma
• Eli Lilly and Company
• Endocyte Inc.
• Fusion Pharmaceuticals
• ITM Isotope Technologies Munich SE
• Johnson & Johnson Services Inc.
• Lantheus Holdings, Inc.
• Molecular Partners AG
• Nanobiotix
• Novartis AG
• Orano Med
• Pfizer Inc.
• POINT Biopharma Global Inc.
• Precirix NV
• Telix Pharmaceuticals Limited

Tariff Impact Analysis: Key Insights for 2025

Global tariff negotiations across 180+ countries are reshaping supply chains, costs, and competitiveness. This report reflects the latest developments as of April 2025 and incorporates forward-looking insights into the market outlook.

The analysts continuously track trade developments worldwide, drawing insights from leading global economists and over 200 industry and policy institutions, including think tanks, trade organizations, and national economic advisory bodies. This intelligence is integrated into forecasting models to provide timely, data-driven analysis of emerging risks and opportunities.

What's Included in This Edition:

• Tariff-adjusted market forecasts by region and segment
• Analysis of cost and supply chain implications by sourcing and trade exposure
• Strategic insights into geographic shifts

Buyers receive a free July 2025 update with:

• Finalized tariff impacts and new trade agreement effects
• Updated projections reflecting global sourcing and cost shifts
• Expanded country-specific coverage across the industry