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Bladder Cancer: Eight-Market Drug Forecast And Market Analysis

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    Report

  • 67 Pages
  • March 2025
  • Region: Global
  • GlobalData
  • ID: 6091030
This report covers the 8MM (US, France, Germany, Italy, Spain, UK, China, and Japan) and includes an assessment of the disease epidemiology and 10-year patient-based forecast (PBF) across the 8MM for marketed and late-stage pipeline therapies, with a launch date assessment by market for bladder cancer.

These sales forecasts leverage data on pharmaceutical sales and drug availability from the analyst’s World Markets Healthcare (WMH) and POLI Price Intelligence databases.

This report includes an assessment of the disease epidemiology and 10-year patient-based forecast (PBF) across the 8MM for marketed and late-stage pipeline therapies, with a launch date assessment by market for bladder cancer. These sales forecasts leverage data on pharmaceutical sales and drug availability from the analyst’s World Markets Healthcare (WMH) and POLI Price Intelligence databases.

In the 8MM, the number of diagnosed incident cases of bladder cancer will grow from 279,419 cases in 2023 to 341,879 cases by 2033.

Common bladder cancer market drivers across the 8MM include:

  • The sales of Padcev represent the most high-profile driver totaling $3.6 billion in 2033.
  • Newly approved and pipeline agents, such as Adstiladrin, TAR200, and cretostimogene grenadenorepvec, aimed at improving outcomes for BCG-unresponsive non-muscle invasive bladder cancer (NMIBC), are key market drivers.
  • Several late-stage pipeline drugs with novel MOAs have received orphan drug designation from the FDA. As such, they are granted a potential seven years of market exclusivity after approval.

Common barriers to market growth experienced across the 8MM include:

  • Future patent expiry of key players, such as Keytruda and Opdivo, could introduce an influx of lower-cost and effective biosimilars, further escalating the competition in the space.
  • Implementing gene therapy into a urology practice poses challenges in terms of storage and handling requirements as well as the specialized training required to administer these products.
  • Higher costs of therapy for newly approved and pipeline agents will impact reimbursement in NMIBC, which has a large market size, and has traditionally been treated with low-cost chemotherapy and BCG.

Key Highlights

  • Report deliverables include a Pdf report and Excel-based forecast model
  • Forecasts includes the 8MM
  • Forecasts covers from 2023-2033
  • The analyst valued the bladder cancer market in the 8MM at $3 billion in 2023 and expects the market to increase to $16 billion by 2033
  • In the base year, 2023, immunotherapy drugs contributed the highest sales, 61%, to the bladder cancer market. The current main immunotherapies used in bladder cancer are the ICIs Keytruda, Opdivo, and Bavencio, and the recently approved immunostimulant Anktiva (for NMIBC).
  • The class of ADCs, which includes Padcev, Enhertu, Trodelvy, and Aidix, was the second largest contributor, taking 23% of the bladder cancer market in 2023, and is expected to grow throughout the forecast period.
  • Gene therapy is anticipated to triple from 4% of the total market in 2023 to 12% in 2033. The rapid adoption rate of Adstiladrin and upcoming product launches are due to the drug class’s primary indication, second-line treatment in high-risk NMIBC, an area of high unmet need.

Scope

  • Overview of bladder cancer, including epidemiology, symptoms, diagnosis, and disease management.
  • Annualized bladder cancer therapeutics market revenue, cost of therapy per patient, and treatment usage patterns forecast from 2023 to 2033.
  • Key topics covered include strategic competitor assessment, market characterization, unmet needs, clinical trial mapping, and implications of these factors for the bladder cancer therapeutics market.
  • Pipeline analysis: comprehensive data assessing emerging trends and mechanisms of action under development for bladder cancer treatment. The most promising candidates in Phase III and Phase IIb development are profiled.
  • Analysis of the current and future market competition in the global bladder cancer therapeutics market. Insightful review of the key industry drivers, restraints and challenges. Each trend is independently researched to provide qualitative analysis of its implications.

Reasons to Buy

  • Develop and design your in-licensing and out-licensing strategies through a review of pipeline products and technologies, and by identifying the companies with the most robust pipeline.
  • Develop business strategies by understanding the trends shaping and driving the global bladder cancer therapeutics market.
  • Drive revenues by understanding the key trends, innovative products and technologies, market segments, and companies likely to impact the global bladder cancer therapeutics market in the future.
  • Formulate effective sales and marketing strategies by understanding the competitive landscape and by analyzing the performance of various competitors.
  • Identify emerging players with potentially strong product portfolios and create effective counter-strategies to gain a competitive advantage.
  • Organize your sales and marketing efforts by identifying the market categories and segments that present maximum opportunities for consolidations, investments and strategic partnerships

Table of Contents

1. Preface
1.1. Contents
1.2. Abbreviations
1.3. Related Reports
2. Executive Summary
3. Disease Overview
3.1. Overview of Bladder Cancer
3.2. Bladder Cancer Market Strength, Weakness, Opportunity, and Threat Analysis
4. Epidemiology
4.1. Diagnosed Incident Cases Both Sexes
4.2. Age-Specific Diagnosed Incident Cases
4.3. Sex-Specific Diagnosed Incident Cases
4.4. Diagnosed Incident Cases by Type, Sex, Age
4.5. Diagnosed Incident Cases by Stage at Diagnosis
4.6. Diagnosed Incident Cases by Tumor Stage at Diagnosis
4.7. Diagnosed Incident Cases of Stage Ta Bladder Cancer by Grade
4.8. Diagnosed Incident Cases of Stage of Bladder Cancer by Broad Classification
4.9. Diagnosed Incident Cases of Stage of NMIBC by Risk Group
4.10. Diagnosed Incident Cases of Bladder Cancer by Mutations and Biomarkers
4.11. Five-Year Diagnosed Prevalent Cases of Bladder Cancer
4.12. Five-Year Diagnosed Prevalent Cases of Bladder Cancer by Tumor Stage
4.13. Five-Year Diagnosed Prevalent Cases of Bladder Cancer by Broad Classification
4.14. Five-Year Diagnosed Prevalent Cases of Bladder Cancer by Relapse or Recurrence
4.15. Five-Year Diagnosed Prevalent Cases of Bladder Cancer by Treatment
5. Disease Management
5.1. Treatment Guidelines
5.2. Treatment Paradigm - First-Line Therapy in Non-Muscle Invasive Bladder Cancer
5.3. Treatment Paradigm - First-Line Therapy in Muscle Invasive Bladder Cancer
5.4. Treatment Paradigm - Locally Advanced/Metastatic Bladder Cancer
5.5. KOL Insight on the Bladder Cancer Treatment Algorithm
6. Unmet Needs and Opportunities
6.1. Unmet Needs in Bladder Cancer
6.2. Unmet Needs in Bladder Cancer (2)
6.3. Unmet Needs in Bladder Cancer (3)
6.4. Unmet Needs in Bladder Cancer (4)
7. Competitive Landscape Assessment
7.1. Pipeline Drugs Overview
7.2. Competitive Landscape Methodology
7.3. Competitive Assessment - Intravesical Delivered Therapies for NMIBC
7.4. Competitive Assessment - Gene Therapies for NMIBC
7.5. Competitive Assessment - Antibody-Drug Conjugates
8. Market Outlook
8.1. Bladder Cancer Market Forecast
8.2. Bladder Cancer Market Forecast by Class
8.3. Bladder Cancer Market Drivers and Barriers
9. Appendix
9.1. Primary Research: KOL Information
9.2. Sources Used and Not Used to Forecast Diagnosed Incident Cases
9.3. Sources Used to Forecast Diagnosed Incident Cases by Stage at Diagnosis
9.4. Sources Used to Forecast Diagnosed Incident Cases by Tumor Stage at Diagnosis
9.5. Sources Used to Forecast Diagnosed Incident Cases of Stage Ta Bladder Cancer by Grade
9.6. Sources Used to Forecast Diagnosed Incident and Five-Year Diagnosed Prevalent Cases by Broad Classification
9.7. Sources Used to Forecast Diagnosed Incident Cases of NMIBC by Risk Group
9.8. Sources Used to Forecast Diagnosed Incident Cases by Mutations and Biomarkers
9.9. Sources Used to Forecast the Five-Year Diagnosed Prevalent Cases
9.10. Sources Used to Forecast the Five-Year Diagnosed Prevalent Cases by Relapse or Recurrence
9.11. Sources Used to Forecast the Five-Year Diagnosed Prevalent Cases by Treatment
9.12. Sources and Methodology
9.13. Epidemiological Forecast Insight
9.14. Strengths and Limitations
9.15. About the Authors
9.16. About the Authors (2)
9.17. About the Authors (3)
9.18. About the Authors (4)
9.19. Bibliography

Companies Mentioned (Partial List)

A selection of companies mentioned in this report includes, but is not limited to:

  • AstraZeneca
  • Merck
  • Bristol-Myers Squibb
  • Gilead Sciences LLC
  • Roche
  • Pfizer
  • Immunomedics Inc
  • Astellas Pharma Co Ltd
  • Johnson & Johnson
  • Daiichi Sankyo Co Ltd
  • Ferring Pharmaceuticals Ltd
  • ImmunityBio Inc
  • BeiGene Ltd
  • Bicycle Therapeutics Inc
  • CG Oncology Inc
  • Shanghai Miracogen Inc
  • Fidia farmaceutici SpA
  • Therlase Inc
  • enGene Holdings Inc
  • UroGen Pharma Inc