The Global Ophthalmic Anti-VEGF Therapeutics Market was valued at USD 16.9 billion in 2024 and is estimated to grow at a CAGR of 5.2% to reach USD 28.6 billion by 2034.
Market expansion is driven by the rise in retinal disorders, the global increase in diabetes, continued population aging, and the rapid establishment of specialized ophthalmic facilities. Anti-VEGF drugs work by blocking VEGF activity, which contributes to abnormal blood vessel formation in the retina, making these therapies essential for conditions such as age-related macular degeneration (AMD), diabetic macular edema (DME), and retinal vein occlusion (RVO). Increasing cases of diabetic retinopathy, diabetes-related macular complications, and age-related visual degeneration continue to widen the treatment pool. At the same time, continual research efforts are delivering improved molecules with longer durability, enhanced safety, and multi-pathway targeting capabilities. These innovations are reshaping treatment patterns by expanding options for first-line therapies, optimizing switching strategies, and supporting longer dosing intervals. As the therapeutic landscape diversifies, premium drug categories remain commercially viable due to clinical performance and sustained demand across aging and diabetic populations.
The Eylea segment held a 57.2% share in 2024, supported by strong clinical outcomes, reliable safety, and longer dosing cycles enabled by its higher-dose formulation. Its broad adoption in diabetic retinal diseases is reinforced by the fast-growing global diabetic population, which consistently drives long-term utilization and high annual treatment volumes.
The age-related macular degeneration segment accounted for a 48.3% share in 2024 and is expected to reach USD 13.2 billion through 2034. As AMD primarily affects older adults, markets with rapidly expanding senior populations continue to see rising therapy demand. Anti-VEGF treatment remains the cornerstone of AMD care, resulting in steady growth across aging demographics worldwide.
North America Ophthalmic Anti-VEGF Therapeutics Market held a 64.8% share in 2024, supported by a large patient base with AMD, DME, and diabetic retinopathy. The region benefits from robust clinical infrastructure, extensive specialist availability, and highly efficient supply and administration systems that facilitate ongoing treatment adherence.
Major companies participating in the Global Ophthalmic Anti-VEGF Therapeutics Market include AMGEN, Astellas, Biocon Biologics, Biogen, CELLTRION, Intas Pharmaceuticals, KANGHONG PHARMACEUTICALS, LUPIN, NOVARTIS, REGENERON, Reliance Life Sciences, Roche, SANDOZ, STADA, and Teva. Companies operating in the Ophthalmic Anti-VEGF Therapeutics Market are adopting several strategic approaches to strengthen their position. Many are investing heavily in next-generation molecules with extended durability to reduce injection burden and improve patient outcomes. Firms are expanding clinical trials across multiple retinal conditions to broaden therapeutic indications and secure a larger market share. Partnerships, co-development agreements, and biosimilar expansion strategies are helping companies reach new geographies and diversify product portfolios. Manufacturers are also prioritizing real-world evidence programs to reinforce clinical value and support reimbursement negotiations.
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Market expansion is driven by the rise in retinal disorders, the global increase in diabetes, continued population aging, and the rapid establishment of specialized ophthalmic facilities. Anti-VEGF drugs work by blocking VEGF activity, which contributes to abnormal blood vessel formation in the retina, making these therapies essential for conditions such as age-related macular degeneration (AMD), diabetic macular edema (DME), and retinal vein occlusion (RVO). Increasing cases of diabetic retinopathy, diabetes-related macular complications, and age-related visual degeneration continue to widen the treatment pool. At the same time, continual research efforts are delivering improved molecules with longer durability, enhanced safety, and multi-pathway targeting capabilities. These innovations are reshaping treatment patterns by expanding options for first-line therapies, optimizing switching strategies, and supporting longer dosing intervals. As the therapeutic landscape diversifies, premium drug categories remain commercially viable due to clinical performance and sustained demand across aging and diabetic populations.
The Eylea segment held a 57.2% share in 2024, supported by strong clinical outcomes, reliable safety, and longer dosing cycles enabled by its higher-dose formulation. Its broad adoption in diabetic retinal diseases is reinforced by the fast-growing global diabetic population, which consistently drives long-term utilization and high annual treatment volumes.
The age-related macular degeneration segment accounted for a 48.3% share in 2024 and is expected to reach USD 13.2 billion through 2034. As AMD primarily affects older adults, markets with rapidly expanding senior populations continue to see rising therapy demand. Anti-VEGF treatment remains the cornerstone of AMD care, resulting in steady growth across aging demographics worldwide.
North America Ophthalmic Anti-VEGF Therapeutics Market held a 64.8% share in 2024, supported by a large patient base with AMD, DME, and diabetic retinopathy. The region benefits from robust clinical infrastructure, extensive specialist availability, and highly efficient supply and administration systems that facilitate ongoing treatment adherence.
Major companies participating in the Global Ophthalmic Anti-VEGF Therapeutics Market include AMGEN, Astellas, Biocon Biologics, Biogen, CELLTRION, Intas Pharmaceuticals, KANGHONG PHARMACEUTICALS, LUPIN, NOVARTIS, REGENERON, Reliance Life Sciences, Roche, SANDOZ, STADA, and Teva. Companies operating in the Ophthalmic Anti-VEGF Therapeutics Market are adopting several strategic approaches to strengthen their position. Many are investing heavily in next-generation molecules with extended durability to reduce injection burden and improve patient outcomes. Firms are expanding clinical trials across multiple retinal conditions to broaden therapeutic indications and secure a larger market share. Partnerships, co-development agreements, and biosimilar expansion strategies are helping companies reach new geographies and diversify product portfolios. Manufacturers are also prioritizing real-world evidence programs to reinforce clinical value and support reimbursement negotiations.
Comprehensive Market Analysis and Forecast
- Industry trends, key growth drivers, challenges, future opportunities, and regulatory landscape
- Competitive landscape with Porter’s Five Forces and PESTEL analysis
- Market size, segmentation, and regional forecasts
- In-depth company profiles, business strategies, financial insights, and SWOT analysis
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Table of Contents
Chapter 1 Methodology and Scope
Chapter 2 Executive Summary
Chapter 3 Industry Insights
Chapter 4 Competitive Landscape, 2024
Chapter 5 Market Estimates and Forecast, by Anti-VEGF Therapies, 2021-2034 ($ Mn)
Chapter 6 Market Estimates and Forecast, by Drug Type, 2021-2034 ($ Mn)
Chapter 7 Market Estimates and Forecast, by Indication, 2021-2034 ($ Mn)
Chapter 8 Market Estimates and Forecast, by Region, 2021-2034 ($ Mn)
Chapter 9 Company Profiles
Companies Mentioned
The companies profiled in this Ophthalmic Anti-VEGF Therapeutics market report include:- AMGEN
- Astellas
- Biocon Biologics
- Biogen
- CELLTRION
- Intas Pharmaceuticals
- KANGHONG PHARMACEUTICALS
- LUPIN
- NOVARTIS
- REGENERON
- Reliance Life Sciences
- Roche
- SANDOZ
- STADA
- teva
Table Information
| Report Attribute | Details |
|---|---|
| No. of Pages | 142 |
| Published | December 2025 |
| Forecast Period | 2024 - 2034 |
| Estimated Market Value ( USD | $ 16.9 Billion |
| Forecasted Market Value ( USD | $ 28.6 Billion |
| Compound Annual Growth Rate | 5.2% |
| Regions Covered | Global |
| No. of Companies Mentioned | 16 |
