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Cryptococcal Meningitis Epidemiology Forecast 2025-2034

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    Report

  • 150 Pages
  • June 2025
  • Region: Global
  • Expert Market Research
  • ID: 6092303
Around 152,000 cases of cryptococcal meningitis occur each year among people living with HIV worldwide, leading to an estimated 112,000 deaths, mostly in sub-Saharan Africa. This infection is a major risk for people with HIV/AIDS, particularly in countries with high HIV prevalence and limited access to healthcare.

Cryptococcal Meningitis Epidemiology Forecast Report Coverage

The “Cryptococcal Meningitis Epidemiology Forecast Report 2025-2034” offers comprehensive information on the prevalence and demographics of cryptococcal meningitis. It projects the future incidence and prevalence rates of cryptococcal meningitis across various populations. The study covers age and type as major determinants of the cryptococcal meningitis-affected population. The report highlights patterns in the prevalence of cryptococcal meningitis over time and projects future trends based on multiple variables.

The report provides a comprehensive overview of the disease, as well as historical and projected data on the epidemiology of cryptococcal meningitis in the 8 major markets.

Regions Covered

  • The United States
  • Germany
  • France
  • Italy
  • Spain
  • The United Kingdom
  • Japan
  • India

Cryptococcal Meningitis: Disease Overview

Cryptococcal meningitis is a serious fungal infection that affects the brain and spinal cord. It is caused by the fungus Cryptococcus (commonly Cryptococcus neoformans or Cryptococcus gattii). The infection is frequently seen in people with weakened immune systems, such as HIV/AIDS patients. Immunosuppressive treatments (chemotherapy, organ transplants, or long-term steroid use) and environmental exposure are also risk factors of the disease.

Cryptococcal Meningitis: Treatment Overview

The treatment of cryptococcal meningitis typically involves a combination of antifungal medications, which is administered for several weeks to months, depending on the severity of the infection and the patient's immune status. The treatment plan is often started with amphotericin B, which is administered intravenously for severe cases, followed by fluconazole for a longer duration to prevent recurrence. In some cases, additional medications may be required to manage symptoms like pain or fever.

Epidemiology

The cryptococcal meningitis epidemiology section offers information on the patient pool from history to the present as well as the projected trend for each of the 8 major markets. The publisher provides both current and predicted trends for cryptococcal meningitis by examining a wide range of studies. Additionally, the report covers the diagnosed patient pool for cryptococcal meningitis and their trends. The data is broken down into specific categories, such as the total diagnosed cases across different age groups and patient pools.
  • Around 1 million cases of cryptococcal meningitis are reported each year. The widespread use of corticosteroids and improved survival rates in cancer patients are contributing to the growing incidence of the disease.
  • Approximately 152,000 cases of cryptococcal meningitis occur each year worldwide among HIV affected individuals.
  • Cryptococcal meningitis is rare in immunocompetent patients, but some reports suggest that up to 20% of cases occur in people with a healthy immune system.
  • Cryptococcal meningitis is responsible for an estimated 112,000 deaths annually in people living with HIV, with the majority occurring in sub-Saharan Africa.

Country-wise Cryptococcal Meningitis Epidemiology

The cryptococcal meningitis epidemiology data and findings for the United States, Germany, Spain, Italy, France, the United Kingdom, Japan, and India are also provided in the epidemiology section.

The epidemiology of cryptococcal meningitis varies significantly between countries due to differences in HIV prevalence, healthcare access, environmental factors, and local fungal strains, among others. Studies from the United States, Australia, Papua New Guinea, and British Columbia (Canada) show that the death rates from Cryptococcus gattii range from 13% to 33%.

Scope of the Report

  • The report covers a detailed analysis of signs and symptoms, causes, risk factors, pathophysiology, diagnosis, treatment options, and classification/types of cryptococcal meningitis based on several factors.
  • The Cryptococcal Meningitis Epidemiology Forecast Report covers data for the eight major markets (the US, France, Germany, Italy, Spain, the UK, Japan, and India).
  • The report helps to identify the patient population, and the unmet needs of cryptococcal meningitis are highlighted along with an assessment of the disease's risk and burden.

Key Questions Answered

  • What are the key findings of cryptococcal meningitis epidemiology in the 8 major markets?
  • What will be the total number of patients with cryptococcal meningitis across the 8 major markets during the forecast period?
  • What was the country-wise prevalence of cryptococcal meningitis in the 8 major markets in the historical period?
  • Which country will have the highest number of cryptococcal meningitis patients during the forecast period of 2025-2034?
  • Which key factors would influence the shift in the patient population of cryptococcal meningitis during the forecast period of 2025-2034?
  • What are the currently available treatments for cryptococcal meningitis?
  • What are the disease risks, signs, symptoms, and unmet needs of cryptococcal meningitis?

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Table of Contents

1 Preface
1.1 Introduction
1.2 Objectives of the Study
1.3 Research Methodology and Assumptions
2 Executive Summary
3 Cryptococcal Meningitis Market Overview - 8 MM
3.1 Cryptococcal Meningitis Market Historical Value (2018-2024)
3.2 Cryptococcal Meningitis Market Forecast Value (2025-2034)
4 Cryptococcal Meningitis Epidemiology Overview - 8 MM
4.1 Cryptococcal Meningitis Epidemiology Scenario (2018-2024)
4.2 Cryptococcal Meningitis Epidemiology Forecast
5 Disease Overview
5.1 Signs and Symptoms
5.2 Causes
5.3 Risk Factors
5.4 Guidelines and Stages
5.5 Pathophysiology
5.6 Screening and Diagnosis
6 Patient Profile
6.1 Patient Profile Overview
6.2 Patient Psychology and Emotional Impact Factors
7 Epidemiology Scenario and Forecast - 8 MM
7.1 Key Findings
7.2 Assumptions and Rationale
7.3 Cryptococcal Meningitis Epidemiology Scenario in 8MM (2018-2034)
8 Epidemiology Scenario and Forecast: United States
8.1 Cryptococcal Meningitis Epidemiology Scenario and Forecast in The United States (2018-2034)
9 Epidemiology Scenario and Forecast: United Kingdom
9.1 Cryptococcal Meningitis Epidemiology Scenario and Forecast in United Kingdom (2018-2034)
10 Epidemiology Scenario and Forecast: Germany
10.1 Cryptococcal Meningitis Epidemiology Scenario and Forecast in Germany (2018-2034)
11 Epidemiology Scenario and Forecast: France
11.1 Cryptococcal Meningitis Epidemiology Scenario and Forecast in France
12 Epidemiology Scenario and Forecast: Italy
12.1 Cryptococcal Meningitis Epidemiology Scenario and Forecast in Italy (2018-2034)
13 Epidemiology Scenario and Forecast: Spain
13.1 Cryptococcal Meningitis Epidemiology Scenario and Forecast in Spain (2018-2034)
14 Epidemiology Scenario and Forecast: Japan
14.1 Cryptococcal Meningitis Epidemiology Scenario and Forecast in Japan (2018-2034)
15 Epidemiology Scenario and Forecast: India
15.1 Cryptococcal Meningitis Epidemiology Scenario and Forecast in India (2018-2034)
16 Patient Journey17 Treatment Challenges and Unmet Needs18 Key Opinion Leaders (KOL) Insights