Infantile Spasm Epidemiology Forecast 2025-2034

Infantile spasm is estimated to affect around 1 in 2,000 to 4,000 babies. Studies show that the average age of diagnosis is between the ages of 4 and 7 months. Infantile spasms last for 1 or 2 seconds and typically occur in a series or cluster every 5 to 10 seconds.

Infantile Spasm Epidemiology Forecast Report Coverage

The “Infantile Spasm Epidemiology Forecast Report 2025-2034” offers comprehensive information on the prevalence and demographics of infantile spasm. It projects the future incidence and prevalence rates of infantile spasm across various populations. The study covers age and type as major determinants of the infantile spasm-affected population. The report highlights patterns in the prevalence of infantile spasm over time and projects future trends based on multiple variables.

The report provides a comprehensive overview of the disease, as well as historical and projected data on the epidemiology of infantile spasm in the 8 major markets.

Regions Covered

• The United States
• Germany
• France
• Italy
• Spain
• The United Kingdom
• Japan
• India

Infantile Spasm: Disease Overview

Infantile spasms (IS) is a severe form of epilepsy that typically begins in infancy. These spasms often occur in clusters and can be accompanied by developmental regression. The condition causes abnormal brain activity and is characterized by sudden, brief seizures. Mutations associated with certain syndromes like tuberous sclerosis complex (TSC) or other metabolic disorders can put an infant at a higher risk of infantile spasms.

Infantile Spasm: Treatment Overview

Adrenocorticotropic hormone (ACTH) shots are commonly given to the affected child for around 6 weeks to manage infantile spasms. Oral prednisolone, a synthetic form of a corticosteroid hormone, is also found to be an effective treatment for the condition. Vigabatrin (Sabril®) is an anti-seizure medication that is taken orally as a pill or liquid. Throughout the course of treatment, the child has to undergo repeat EEG tests to monitor if the treatment is working.

Epidemiology

The infantile spasm epidemiology section offers information on the patient pool from history to the present as well as the projected trend for each of the 8 major markets. The publisher provides both current and predicted trends for infantile spasm by examining a wide range of studies. Additionally, the report covers the diagnosed patient pool for infantile spasm and their trends. The data is broken down into specific categories, such as the total diagnosed cases across different age groups and patient pools.

• The incidence of infantile spasms is estimated to be 1.6 to 4.5 per 10,000 live births, accounting for nearly 2,000 to 2,500 new cases each year.
• Around 1 in 2,000 to 4,000 babies are affected by infantile spasms, with the average age of diagnosis reported between 4 months and 7 months.
• Infantile spasms are observed to occur in all ethnic groups. Studies show that Down syndrome is the most frequently occurring chromosomal abnormality linked with the condition.
• The mortality rate ranges from 5% to 30% by the age of 3. Among those who survive, 80% to 90% experience developmental delays, and 50% to 70% later develop different types of seizures.

Country-wise Infantile Spasm Epidemiology

The infantile spasm epidemiology data and findings for the United States, Germany, Spain, Italy, France, the United Kingdom, Japan, and India are also provided in the epidemiology section.

The epidemiology of infantile spasm varies significantly between countries due to differences in the prevalence of conditions like cerebral palsy, neurogenetic syndromes, or brain malformations, factors such as prenatal and perinatal care, maternal health, infections, or exposure to toxins, and genetic predisposition, among others. In the United States, infantile spasms affect over 1,200 infants annually.

Scope of the Report

• The report covers a detailed analysis of signs and symptoms, causes, risk factors, pathophysiology, diagnosis, treatment options, and classification/types of infantile spasm based on several factors.
• The Infantile Spasm Epidemiology Forecast Report covers data for the eight major markets (the US, France, Germany, Italy, Spain, the UK, Japan, and India).
• The report helps to identify the patient population, and the unmet needs of infantile spasm are highlighted along with an assessment of the disease's risk and burden.

Key Questions Answered

• What are the key findings of infantile spasm epidemiology in the 8 major markets?
• What will be the total number of patients with infantile spasms across the 8 major markets during the forecast period?
• What was the country-wise prevalence of infantile spasm in the 8 major markets in the historical period?
• Which country will have the highest number of infantile spasm patients during the forecast period of 2025-2034?
• Which key factors would influence the shift in the patient population of infantile spasm during the forecast period of 2025-2034?
• What are the currently available treatments for infantile spasms?
• What are the disease risks, signs, symptoms, and unmet needs of infantile spasm?

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