Batten disease is an autosomal recessive metabolic disorder that causes waste material to accumulate in the brain cells. Juvenile Batten disease (CLN3) is the most common type of Batten disease. In the United States, Batten disease is estimated to affect around 3 in every 100,000 newborns.
The report provides a comprehensive overview of the disease, as well as historical and projected data on the epidemiology of Batten disease in the 8 major markets.
The epidemiology of Batten disease varies significantly between countries due to differences in genetic backgrounds, ethnic groups, healthcare access, diagnostic capabilities, and public and medical awareness of the condition. The types of mutations and the affected genes may also vary across populations, leading to differing prevalence and incidence data. In the United States, approximately 2 to 4 per 100,000 children are affected by Batten disease.
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Batten Disease Epidemiology Forecast Report Coverage
The “Batten Disease Epidemiology Forecast Report 2025-2034” offers comprehensive information on the prevalence and demographics of Batten disease. It projects the future incidence and prevalence rates of Batten disease across various populations. The study covers age and type as major determinants of the Batten disease-affected population. The report highlights patterns in the prevalence of Batten disease over time and projects future trends based on multiple variables.The report provides a comprehensive overview of the disease, as well as historical and projected data on the epidemiology of Batten disease in the 8 major markets.
Regions Covered
- The United States
- Germany
- France
- Italy
- Spain
- The United Kingdom
- Japan
- India
Batten Disease: Disease Overview
Batten disease, also known as neuronal ceroid lipofuscinosis (NCL), is characterized by the progressive loss of vision, cognitive function, and motor skills. This rare, inherited neurodegenerative disorder primarily affects children and is a result of mutations in various genes. Since the disease causes neurodegeneration, it ultimately leads to the death of the child. Common symptoms include vision loss, seizures, behavioral changes and personality shifts, and thinking and reasoning issues.Batten Disease: Treatment Overview
Currently, there is no cure for Batten disease. Treatment approaches include seizure management with anti-epileptic medications to control seizures, nutritional support to manage feeding difficulties and malnutrition, and vision aids to assist with vision loss. Physical and occupational therapy is recommended to help with motor skills and mobility. New treatments such as gene therapy, enzyme replacement therapy, and other experimental approaches are actively being explored by pharmaceutical and biotechnology companies.Epidemiology
The Batten disease epidemiology section offers information on the patient pool from history to the present as well as the projected trend for each of the 8 major markets. The publisher provides both current and predicted trends for Batten disease by examining a wide range of studies. Additionally, the report covers the diagnosed patient pool for Batten disease and their trends. The data is broken down into specific categories, such as the total diagnosed cases across different age groups and patient pools.- Batten disease has 14 known types based on the age when symptoms appear, with CLN3 or juvenile Batten disease being the most prevalent disease form. The onset of CLN3 symptoms occurs typically between ages 5 to 15.
- It is estimated that nearly 14,000 children have Batten disease worldwide. Depending on the age of onset and the form of the disease, the life expectancy of the patient may vary.
- The incidence of Batten disease is reported to be 2 to 4 per 100,000.
- Batten disease affects between 100 and 150 children and young adults in the United Kingdom.
Country-wise Batten Disease Epidemiology
The Batten disease epidemiology data and findings for the United States, Germany, Spain, Italy, France, the United Kingdom, Japan, and India are also provided in the epidemiology section.The epidemiology of Batten disease varies significantly between countries due to differences in genetic backgrounds, ethnic groups, healthcare access, diagnostic capabilities, and public and medical awareness of the condition. The types of mutations and the affected genes may also vary across populations, leading to differing prevalence and incidence data. In the United States, approximately 2 to 4 per 100,000 children are affected by Batten disease.
Scope of the Report
- The report covers a detailed analysis of signs and symptoms, causes, risk factors, pathophysiology, diagnosis, treatment options, and classification/types of Batten disease based on several factors.
- The Batten Disease Epidemiology Forecast Report covers data for the eight major markets (the US, France, Germany, Italy, Spain, the UK, Japan, and India).
- The report helps to identify the patient population, and the unmet needs of Batten disease are highlighted along with an assessment of the disease's risk and burden.
Key Questions Answered
- What are the key findings of Batten disease epidemiology in the 8 major markets?
- What will be the total number of patients with Batten disease across the 8 major markets during the forecast period?
- What was the country-wise prevalence of Batten disease in the 8 major markets in the historical period?
- Which country will have the highest number of Batten disease patients during the forecast period of 2025-2034?
- Which key factors would influence the shift in the patient population of Batten disease during the forecast period of 2025-2034?
- What are the currently available treatments for Batten disease?
- What are the disease risks, signs, symptoms, and unmet needs of Batten disease?
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Table of Contents
1 Preface
3 Batten Disease Market Overview - 8 MM
4 Batten Disease Epidemiology Overview - 8 MM
5 Disease Overview
6 Patient Profile
7 Epidemiology Scenario and Forecast - 8 MM
8 Epidemiology Scenario and Forecast: United States
9 Epidemiology Scenario and Forecast: United Kingdom
10 Epidemiology Scenario and Forecast: Germany
11 Epidemiology Scenario and Forecast: France
12 Epidemiology Scenario and Forecast: Italy
13 Epidemiology Scenario and Forecast: Spain
14 Epidemiology Scenario and Forecast: Japan
15 Epidemiology Scenario and Forecast: India