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North America Nucleic Acid Isolation and Purification Market Size, Share & Trends Analysis Report by Product (Kits & Reagents, Instruments), Type, Method (Column-based, Magnetic Beads), Application, End-use, Country with Growth Forecasts, 2025-2030

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    Report

  • 120 Pages
  • May 2025
  • Region: North America
  • Grand View Research
  • ID: 6098076
The North America Nucleic Acid Isolation and Purification Market was valued at USD 2.39 billion in 2024, and is projected to reach USD 4.15 billion by 2030, rising at a CAGR of 10.00%. This growth is driven by the increasing demand for advanced molecular diagnostics, rising investments in genomics and personalized medicine, and expanding drug discovery and clinical research applications. Technological advancements in automation and high-throughput systems fuel market expansion, alongside the growing prevalence of genetic disorders and infectious diseases that require accurate nucleic acid analysis.

Moreover, growing awareness and adoption of precision agriculture and environmental genomics are emerging as important growth drivers for the nucleic acid isolation and purification market. In precision agriculture, nucleic acid technologies enable detailed genetic analysis of crops and soil microbiomes, improving yield, disease resistance, and sustainability. Similarly, environmental genomics applications involve monitoring biodiversity and detecting pathogens in ecosystems. These expanding uses create new demand for advanced nucleic acid isolation tools, broadening the market beyond traditional healthcare and research sectors. As industries recognize the value of genetic insights for optimizing resources and environmental management, market growth is further accelerated.

However, the high costs associated with advanced automated nucleic acid isolation systems and consumables pose a significant restraint, particularly for smaller laboratories and emerging markets. Additionally, the complexity of specific technologies and the need for specialized training can limit widespread adoption. Regulatory challenges and strict compliance requirements further slow market expansion. These factors collectively hinder accessibility and affordability, restricting growth despite rising demand for nucleic acid purification solutions.

North America Nucleic Acid Isolation And Purification Market Report Highlights

  • Based on product, the kits & reagents held the largest market share in 2024. This is attributed to their ease of use and broad application in research and diagnostics. Continuous innovation and cost-effectiveness further support their widespread adoption. The instruments segment is expected to grow fastest over the forecast period.
  • The DNA isolation & purification segment dominated the type market share in 2024 and is anticipated to grow at the fastest CAGR over the forecast period. This is driven by increasing demand for DNA analysis in genomics research, clinical diagnostics, and biopharmaceutical development. However, RNA isolation & purification are anticipated to grow at a significant CAGR over the forecast period.
  • The drug discovery & development as an application held the largest market share of 35.76% in 2024 and is anticipated to grow at the fastest CAGR over the forecast period. Rising R&D investments, increased use of nucleic acid analysis for target identification, and the growing demand for precision medicine and biomarker discovery drive this. However, Precision Medicine is anticipated to grow at a significant CAGR over the forecast period.
  • The magnetic beads segment dominated the method segment with the largest share in 2024 and is anticipated to grow at the fastest CAGR over the forecast period. This growth is attributed to its high efficiency, scalability, and ability to deliver rapid, pure nucleic acid isolation, making it ideal for high-throughput and automated applications. However,column-based methods are expected to grow significantly over the forecast period.
  • The hospitals and diagnostic centers segment dominated the end use segment with the largest share in 2024. This growth is attributed to the increasing adoption of nucleic acid-based diagnostic tests, the rising prevalence of infectious and genetic diseases, and the expanding clinical testing infrastructure across the region. However,pharmaceutical & biotechnology companies are expected to grow at the highest rate over the forecast period.

This report addresses:

  • Market intelligence to enable effective decision-making
  • Market estimates and forecasts from 2018 to 2030
  • Growth opportunities and trend analyses
  • Segment and regional revenue forecasts for market assessment
  • Competition strategy and market share analysis
  • Product innovation listings for you to stay ahead of the curve

Why Should You Buy This Report?

  • Comprehensive Market Analysis: Gain detailed insights into the market across major regions and segments.
  • Competitive Landscape: Explore the market presence of key players.
  • Future Trends: Discover the pivotal trends and drivers shaping the future of the market.
  • Actionable Recommendations: Utilize insights to uncover new revenue streams and guide strategic business decisions.

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Table of Contents

Chapter 1. Methodology and Scope
1.1. Market Segmentation & Scope
1.2. Segment Definitions
1.2.1. Product
1.2.2. Type
1.2.3. Application
1.2.4. Method
1.2.5. End Use
1.3. Research Methodology
1.4. Information Procurement
1.5. Information or Data Analysis
1.5.1. Data analysis models
1.6. Market Formulation & Validation
1.7. List of Secondary Sources
1.8. List of Primary Sources
1.9. Objectives
Chapter 2. Executive Summary
2.1. Market Outlook
2.2. Segment Outlook
2.3. Competitive Insights
Chapter 3. North America Nucleic Acid Isolation & Purification Market Variables & Trends
3.1. Market Lineage Outlook
3.1.1. Parent market outlook
3.1.2. Related/ancillary market outlook
3.2. Market Dynamics
3.2.1. Market driver analysis
3.2.1.1. Increasing incidence of cancer, genetic disorders, and infectious diseases
3.2.1.2. Increase in public-private funding for biotechnology and life science research
3.2.1.3. Advancements in automation
3.2.1.4. Growth in NGS technologies
3.2.1.5. Growing demand for genetically modified crops and organisms
3.2.2. Market restraint analysis
3.2.2.1. Expensive instruments and consequent low penetration in emerging countries
3.2.2.2. Challenges related to the use of big data and bioinformatics
3.3. North America Nucleic Acid Isolation & Purification Market Analysis Tools
3.3.1. Industry Analysis - Porter’s
3.3.2. PESTEL Analysis
3.3.3. COVID-19 Impact Analysis
Chapter 4. North America Nucleic Acid Isolation & Purification Market: Product Estimates & Trend Analysis
4.1. Product Segment Dashboard
4.2. North America Nucleic Acid Isolation & Purification Market Product Movement Analysis
4.3. North America Nucleic Acid Isolation & Purification Market Size & Trend Analysis, by Product, 2018 to 2030 (USD Million)
4.4. Kits & Reagents
4.4.1. Kits & Reagents Market Size & Forecasts and Trend Analyses, 2018 to 2030 (USD Million)
4.5. Instrument
4.5.1. Instrument Market Size & Forecasts and Trend Analyses, 2018 to 2030 (USD Million)
4.5.2. Manual
4.5.2.1. Manual Market Size & Forecasts and Trend Analyses, 2018 to 2030 (USD Million)
4.5.3. Automatic
4.5.3.1. Automatic Market Size & Forecasts and Trend Analyses, 2018 to 2030 (USD Million)
Chapter 5. North America Nucleic Acid Isolation & Purification Market: Type Estimates & Trend Analysis
5.1. Type Segment Dashboard
5.2. North America Nucleic Acid Isolation & Purification Market Type Movement Analysis
5.3. North America Nucleic Acid Isolation & Purification Market Size & Trend Analysis, by Type, 2018 to 2030 (USD Million)
5.4. DNA Isolation & Purification
5.4.1. DNA Isolation & Purification Market Size & Forecasts and Trend Analyses, 2018 to 2030 (USD Million)
5.4.2. Genomic DNA Isolation & Purification
5.4.2.1. Genomic DNA Isolation & Purification Market Size & Forecasts and Trend Analyses, 2018 to 2030 (USD Million)
5.4.3. Plasmid DNA Isolation & Purification
5.4.3.1. Plasmid DNA Isolation & Purification Market Size & Forecasts and Trend Analyses, 2018 to 2030 (USD Million)
5.4.4. Viral DNA Isolation & Purification
5.4.4.1. Viral DNA Isolation & Purification Market Size & Forecasts and Trend Analyses, 2018 to 2030 (USD Million)
5.4.5. Other
5.4.5.1. Other Market Size & Forecasts and Trend Analyses, 2018 to 2030 (USD Million)
5.5. RNA Isolation & Purification
5.5.1. RNA Isolation & Purification Market Size & Forecasts and Trend Analyses, 2018 to 2030 (USD Million)
5.5.2. miRNA Isolation & Purification
5.5.2.1. miRNA Isolation & Purification Market Size & Forecasts and Trend Analyses, 2018 to 2030 (USD Million)
5.5.3. mRNA Isolation & Purification
5.5.3.1. mRNA Isolation & Purification Market Size & Forecasts and Trend Analyses, 2018 to 2030 (USD Million)
5.5.4. Total RNA Isolation & Purification
5.5.4.1. Total RNA Isolation & Purification Market Size & Forecasts and Trend Analyses, 2018 to 2030 (USD Million)
5.5.5. Other
5.5.5.1. Other Market Size & Forecasts and Trend Analyses, 2018 to 2030 (USD Million)
Chapter 6. North America Nucleic Acid Isolation & Purification Market: Application Estimates & Trend Analysis
6.1. Application Segment Dashboard
6.2. North America Nucleic Acid Isolation & Purification Market Application Movement Analysis
6.3. North America Nucleic Acid Isolation & Purification Market Size & Trend Analysis, by Application, 2018 to 2030 (USD Million)
6.4. Precision Medicine
6.4.1. Precision Medicine Market Size & Forecasts and Trend Analyses, 2018 to 2030 (USD Million)
6.5. Diagnostics
6.5.1. Diagnostics Market Size & Forecasts and Trend Analyses, 2018 to 2030 (USD Million)
6.6. Drug Discovery & Development
6.6.1. Drug Discovery & Development Market Size & Forecasts and Trend Analyses, 2018 to 2030 (USD Million)
6.7. Agriculture and Animal Research
6.7.1. Agriculture and Animal Research Market Size & Forecasts and Trend Analyses, 2018 to 2030 (USD Million)
6.8. Other Applications
6.8.1. Other Applications Market Size & Forecasts and Trend Analyses, 2018 to 2030 (USD Million)
Chapter 7. North America Nucleic Acid Isolation & Purification Market: Method Estimates & Trend Analysis
7.1. Method Segment Dashboard
7.2. North America Nucleic Acid Isolation & Purification Market Method Movement Analysis
7.3. North America Nucleic Acid Isolation & Purification Market Size & Trend Analysis, by Method, 2018 to 2030 (USD Million)
7.4. Column-based
7.4.1. Column-based Market Size & Forecasts and Trend Analyses, 2018 to 2030 (USD Million)
7.5. Magnetic Beads
7.5.1. Magnetic Beads Market Size & Forecasts and Trend Analyses, 2018 to 2030 (USD Million)
7.6. Reagent-based
7.6.1. Reagent-based Market Size & Forecasts and Trend Analyses, 2018 to 2030 (USD Million)
7.7. Others
7.7.1. Others Market Size & Forecasts and Trend Analyses, 2018 to 2030 (USD Million)
Chapter 8. North America Nucleic Acid Isolation & Purification Market: End Use Estimates & Trend Analysis
8.1. End Use Segment Dashboard
8.2. North America Nucleic Acid Isolation & Purification Market End Use Movement Analysis
8.3. North America Nucleic Acid Isolation & Purification Market Size & Trend Analysis, by End Use, 2018 to 2030 (USD Million)
8.4. Academic Research Institutes
8.4.1. Academic Research Institutes Market Size & Forecasts and Trend Analyses, 2018 to 2030 (USD Million)
8.5. Pharmaceutical & Biotechnology Companies
8.5.1. Pharmaceutical & Biotechnology Companies Market Size & Forecasts and Trend Analyses, 2018 to 2030 (USD Million)
8.6. Contract Research Organizations
8.6.1. Contract Research Organizations Market Size & Forecasts and Trend Analyses, 2018 to 2030 (USD Million)
8.7. Hospitals and Diagnostic Centers
8.7.1. Hospitals and Diagnostic Centers Market Size & Forecasts and Trend Analyses, 2018 to 2030 (USD Million)
8.8. Other End Use
8.8.1. Other End Use Market Size & Forecasts and Trend Analyses, 2018 to 2030 (USD Million)
Chapter 9. North America Nucleic Acid Isolation & Purification Market: Country Estimates & Trend Analysis
9.1. Country Market Share Analysis, 2024 & 2030
9.2. Country Market Dashboard
9.3. U.S.
9.3.1. Key country dynamics
9.3.2. Regulatory framework
9.3.3. Competitive scenario
9.3.4. U.S. market estimates and forecasts 2018 to 2030 (USD Million)
9.4. Canada
9.4.1. Key country dynamics
9.4.2. Regulatory framework
9.4.3. Competitive scenario
9.4.4. Canada market estimates and forecasts 2018 to 2030 (USD Million)
9.5. Mexico
9.5.1. Key country dynamics
9.5.2. Regulatory framework
9.5.3. Competitive scenario
9.5.4. Mexico market estimates and forecasts 2018 to 2030 (USD Million)
Chapter 10. Competitive Landscape
10.1. Participant Categorization
10.2. Company Market Position Analysis, 2024
10.3. Strategy Mapping
10.4. Participants Overview
10.4.1. Thermo Fisher Scientific, Inc.
10.4.1.1. Company overview
10.4.1.2. Financial performance
10.4.1.3. Product benchmarking
10.4.1.4. Strategic initiatives
10.4.2. QIAGEN
10.4.2.1. Company overview
10.4.2.2. Financial performance
10.4.2.3. Product benchmarking
10.4.2.4. Strategic initiatives
10.4.3. Merck KGaA
10.4.3.1. Company overview
10.4.3.2. Financial performance
10.4.3.3. Product benchmarking
10.4.3.4. Strategic initiatives
10.4.4. Illumina, Inc.
10.4.4.1. Company overview
10.4.4.2. Financial performance
10.4.4.3. Product benchmarking
10.4.4.4. Strategic initiatives
10.4.5. Danaher
10.4.5.1. Company overview
10.4.5.2. Financial performance
10.4.5.3. Product benchmarking
10.4.5.4. Strategic initiatives
10.4.6. F. Hoffmann-La Roche Ltd.
10.4.6.1. Company overview
10.4.6.2. Financial performance
10.4.6.3. Product benchmarking
10.4.6.4. Strategic initiatives
10.4.7. Agilent Technologies
10.4.7.1. Company overview
10.4.7.2. Financial performance
10.4.7.3. Product benchmarking
10.4.7.4. Strategic initiatives
10.4.8. Bio-Rad Laboratories, Inc
10.4.8.1. Company overview
10.4.8.2. Financial performance
10.4.8.3. Product benchmarking
10.4.8.4. Strategic initiatives
10.4.9. Takara Bio Inc.
10.4.9.1. Company overview
10.4.9.2. Financial performance
10.4.9.3. Product benchmarking
10.4.9.4. Strategic initiatives
10.4.10. Promega Corporation
10.4.10.1. Company overview
10.4.10.2. Financial performance
10.4.10.3. Product benchmarking
10.4.10.4. Strategic initiatives
List of Tables
Table 1 List of abbreviations
Table 2 North America Nucleic Acid Isolation & Purification Market, by Country, 2018-2030 (USD Million)
Table 3 North America Nucleic Acid Isolation & Purification Market, by Product, 2018-2030 (USD Million)
Table 4 North America Nucleic Acid Isolation & Purification Market, by Type, 2018-2030 (USD Million)
Table 5 North America Nucleic Acid Isolation & Purification Market, by Application, 2018-2030 (USD Million)
Table 6 North America Nucleic Acid Isolation & Purification Market, by Method, 2018-2030 (USD Million)
Table 7 North America Nucleic Acid Isolation & Purification Market, by End Use, 2018-2030 (USD Million)
Table 8 U.S. Nucleic Acid Isolation & Purification Market, by Product, 2018-2030 (USD Million)
Table 9 U.S. Nucleic Acid Isolation & Purification Market, by Type, 2018-2030 (USD Million)
Table 10 U.S. Nucleic Acid Isolation & Purification Market, by Application, 2018-2030 (USD Million)
Table 11 U.S. Nucleic Acid Isolation & Purification Market, by Method, 2018-2030 (USD Million)
Table 12 U.S. Nucleic Acid Isolation & Purification Market, by End Use, 2018-2030 (USD Million)
Table 13 Canada Nucleic Acid Isolation & Purification Market, by Product, 2018-2030 (USD Million)
Table 14 Canada Nucleic Acid Isolation & Purification Market, by Type, 2018-2030 (USD Million)
Table 15 Canada Nucleic Acid Isolation & Purification Market, by Application, 2018-2030 (USD Million)
Table 16 Canada Nucleic Acid Isolation & Purification Market, by Method, 2018-2030 (USD Million)
Table 17 Canada Nucleic Acid Isolation & Purification Market, by End Use, 2018-2030 (USD Million)
Table 18 Mexico Nucleic Acid Isolation & Purification Market, by Product, 2018-2030 (USD Million)
Table 19 Mexico Nucleic Acid Isolation & Purification Market, by Type, 2018-2030 (USD Million)
Table 20 Mexico Nucleic Acid Isolation & Purification Market, by Application, 2018-2030 (USD Million)
Table 21 Mexico Nucleic Acid Isolation & Purification Market, by Method, 2018-2030 (USD Million)
Table 22 Mexico Nucleic Acid Isolation & Purification Market, by End Use, 2018-2030 (USD Million)
List of Figures
Figure 1 Market Research Process
Figure 2 Data Triangulation Techniques
Figure 3 Primary Research Pattern
Figure 4 Market Research Approaches
Figure 5 Market formulation & Validation
Figure 6 North America Nucleic Acid Isolation & Purification Market: Market Outlook
Figure 7 Parent Market Outlook
Figure 8 Related/Ancillary Market Outlook
Figure 9 Penetration and Growth Prospect Mapping
Figure 10 Industry Value Chain Analysis
Figure 11 North America Nucleic Acid Isolation & Purification Market Driver Impact
Figure 12 North America Nucleic Acid Isolation & Purification Market Restraint Impact
Figure 13 North America Nucleic Acid Isolation & Purification Market Strategic Initiatives Analysis
Figure 14 North America Nucleic Acid Isolation & Purification Market: Product Movement Analysis
Figure 15 North America Nucleic Acid Isolation & Purification Market: Product Outlook and Key Takeaways
Figure 16 Kits & Reagents Market Estimates and Forecast, 2018-2030 (USD Million)
Figure 17 Instruments Market Estimates and Forecast, 2018-2030 (USD Million)
Figure 18 Manual Market Estimates and Forecast, 2018-2030 (USD Million)
Figure 19 Automatic Market Estimates and Forecast, 2018-2030 (USD Million)
Figure 20 North America Nucleic Acid Isolation & Purification Market: Type Movement Analysis
Figure 21 North America Nucleic Acid Isolation & Purification Market: Type Outlook and Key Takeaways
Figure 22 DNA Isolation & Purification Market Estimates and Forecasts, 2018-2030 (USD Million)
Figure 23 Genomic DNA Isolation & Purification Market Estimates and Forecast, 2018-2030 (USD Million)
Figure 24 Plasmid DNA Isolation & Purification Market Estimates and Forecast, 2018-2030 (USD Million)
Figure 25 Viral DNA Isolation & Purification Market Estimates and Forecast, 2018-2030 (USD Million)
Figure 26 Other Market Estimates and Forecast, 2018-2030 (USD Million)
Figure 27 RNA Isolation & Purification Market Estimates and Forecast, 2018-2030 (USD Million)
Figure 28 miRNA Isolation & Purification Market Estimates and Forecast, 2018-2030 (USD Million)
Figure 29 mRNA Isolation & Purification Market Estimates and Forecast, 2018-2030 (USD Million)
Figure 30 Total RNA Isolation & Purification Market Estimates and Forecast, 2018-2030 (USD Million)
Figure 31 Other Market Estimates and Forecast, 2018-2030 (USD Million)
Figure 32 North America Nucleic Acid Isolation & Purification Market: Application Movement Analysis
Figure 33 North America Nucleic Acid Isolation & Purification Market: Application Outlook and Key Takeaways
Figure 34 Precision Medicine Market Estimates and Forecasts, 2018-2030 (USD Million)
Figure 35 Diagnostics Market Estimates and Forecasts, 2018-2030 (USD Million)
Figure 36 Drug Discovery & Development Market Estimates and Forecasts, 2018-2030 (USD Million)
Figure 37 Agriculture and Animal Research Market Estimates and Forecasts, 2018-2030 (USD Million)
Figure 38 Other Applications Market Estimates and Forecasts, 2018-2030 (USD Million)
Figure 39 North America Nucleic Acid Isolation & Purification Market: Method Movement Analysis
Figure 40 North America Nucleic Acid Isolation & Purification Market: Method Outlook and Key Takeaways
Figure 41 Column-based Market Estimates and Forecasts, 2018-2030 (USD Million)
Figure 42 Magnetic Beads Market Estimates and Forecasts, 2018-2030 (USD Million)
Figure 43 Reagent-based Market Estimates and Forecasts, 2018-2030 (USD Million)
Figure 44 Other Market Estimates and Forecasts, 2018-2030 (USD Million)
Figure 45 North America Nucleic Acid Isolation & Purification Market: End Use Movement Analysis
Figure 46 North America Nucleic Acid Isolation & Purification Market: End Use Outlook and Key Takeaways
Figure 47 Academic Research Institutes Market Estimates and Forecasts, 2018-2030 (USD Million)
Figure 48 Pharmaceutical & Biotechnology Companies Market Estimates and Forecasts, 2018-2030 (USD Million)
Figure 49 Contract Research Organizations Market Estimates and Forecasts, 2018-2030 (USD Million)
Figure 50 Hospitals and Diagnostic Centers Market Estimates and Forecasts, 2018-2030 (USD Million)
Figure 51 Others Market Estimates and Forecasts, 2018-2030 (USD Million)
Figure 52 North America Nucleic Acid Isolation & Purification Market: Country Movement Analysis
Figure 53 North America Nucleic Acid Isolation & Purification Market: Country Outlook and Key Takeaways
Figure 54 North America Market Estimates and Forecasts, 2018-2030 (USD Million)
Figure 55 U.S. Country Dynamics
Figure 56 U.S. Market Estimates and Forecasts, 2018-2030 (USD Million)
Figure 57 Canada Country Dynamics
Figure 58 Canada Market Estimates and Forecasts, 2018-2030 (USD Million)
Figure 59 Mexico Country Dynamics
Figure 60 Mexico Market Estimates and Forecasts, 2018-2030 (USD Million)

Companies Mentioned

The major companies featured in this North America Nucleic Acid Isolation and Purification market report include:
  • Thermo Fisher Scientific, Inc.
  • QIAGEN
  • Merck KGaA
  • Illumina, Inc.
  • Danaher
  • F. Hoffmann-La Roche Ltd
  • Agilent Technologies
  • Bio-Rad Laboratories, Inc.
  • Takara Bio Inc.
  • Promega Corporation

Table Information