Graves' Disease (Overactive Thyroid) - Global Strategic Business Report

The global market for Graves' Disease (Overactive Thyroid) was estimated at US$397.9 Million in 2024 and is projected to reach US$487.1 Million by 2030, growing at a CAGR of 3.4% from 2024 to 2030. This comprehensive report provides an in-depth analysis of market trends, drivers, and forecasts, helping you make informed business decisions. The report includes the most recent global tariff developments and how they impact the Graves' Disease (Overactive Thyroid) market.

Graves' Disease (Overactive Thyroid) Market - Key Trends & Drivers Summarized

Why Is Graves' Disease Emerging as a Global Public Health Concern?

Graves' disease, the leading cause of hyperthyroidism worldwide, is gaining increasing attention from health systems due to its rising prevalence, underdiagnosis, and its significant impact on metabolic health. This autoimmune disorder, characterized by excessive thyroid hormone production due to thyroid-stimulating immunoglobulins (TSIs), disproportionately affects women and often manifests in individuals aged 30 to 50. Although treatable, if left unmanaged, it can lead to serious complications, including cardiovascular stress, osteoporosis, eye disease (Graves' orbitopathy), and fertility issues.

The global increase in autoimmune diseases, driven by genetic susceptibility, environmental triggers, and lifestyle changes, has pushed Graves' disease further into the spotlight. A heightened awareness of thyroid-related disorders, especially in women's health, and routine thyroid function testing have also contributed to higher detection rates. Public health agencies are increasingly including thyroid health in their preventive care programs, particularly in North America, Europe, and parts of Asia where autoimmune thyroid conditions are more prevalent.

How Are Diagnostics and Treatment Modalities Evolving to Improve Disease Management?

The diagnostic landscape for Graves' disease has significantly improved, driven by the widespread availability of thyroid-stimulating hormone (TSH) assays, radioactive iodine uptake tests, and anti-thyroid antibody profiling. Innovations in imaging technology, such as high-resolution thyroid ultrasound and radionuclide scanning, now allow for more accurate disease staging and differentiation from other forms of hyperthyroidism. This has enabled clinicians to make timely and precise treatment decisions, especially in cases where thyroid nodules or coexisting autoimmune conditions complicate the clinical picture.

Treatment approaches for Graves' disease continue to evolve along three primary paths: antithyroid medications (like methimazole and propylthiouracil), radioactive iodine therapy (RAI), and thyroidectomy. Each option is selected based on patient-specific factors including age, disease severity, pregnancy status, and comorbidities. Recent studies have focused on improving the long-term safety and tolerability of antithyroid drugs, particularly regarding hepatotoxicity and agranulocytosis risks. In parallel, advancements in minimally invasive thyroid surgeries and targeted radioiodine dosing have reduced complications and improved post-treatment quality of life. Novel therapies under investigation include biologics targeting TSH receptor antibodies and immune modulators aimed at altering the disease course rather than just controlling symptoms.

Which Regions and Patient Demographics Are Shaping Market Demand?

Graves' disease exhibits varying prevalence and management patterns across regions. North America leads the market in terms of diagnosis and treatment accessibility, supported by high healthcare expenditure, established endocrinology networks, and public awareness campaigns. Europe follows closely, where countries like the UK and Germany have robust screening programs and comprehensive autoimmune disease management frameworks. In the Asia-Pacific region, rising healthcare infrastructure and increasing urban awareness are contributing to improved diagnosis rates, although large rural populations still face underdiagnosis and limited access to endocrine specialists.

Demographically, women account for over 75% of all diagnosed cases of Graves’ disease, particularly during reproductive years, prompting focused efforts in women's health screening and research. The condition is also increasingly observed in adolescents and perimenopausal women, creating additional layers of diagnostic and therapeutic complexity. Furthermore, the demand for long-term monitoring and ophthalmologic support in cases of thyroid eye disease is creating secondary markets for supportive diagnostics and surgical interventions in specialty care.

The Growth in the Graves’ Disease Market Is Driven by Several Factors…

The growth in the Graves’ disease market is driven by several factors directly tied to evolving treatment protocols, diagnostic innovation, and expanding access to endocrinological care. Technologically, the development of more sensitive immunoassays, refined imaging tools, and companion diagnostic kits has significantly improved disease detection and monitoring capabilities. These advancements enable personalized treatment strategies that minimize risks and enhance long-term outcomes.

On the end-use front, the increasing burden of autoimmune thyroid diseases, along with heightened public awareness and routine screening practices, is expanding the treatment population. The emergence of integrated thyroid care models combining endocrinology, ophthalmology, and surgical expertise is further boosting demand for advanced care services. Additionally, rising healthcare expenditure in emerging economies and the growth of tele-endocrinology platforms are improving access to care in previously underserved regions. With ongoing clinical trials focused on immunotherapies and disease-modifying drugs, the therapeutic landscape is poised for innovation, signaling continued expansion of the Graves’ disease treatment market globally.

Key Insights:

• Market Growth: Understand the significant growth trajectory of the Anti-thyroid Drugs segment, which is expected to reach US$209.7 Million by 2030 with a CAGR of a 3.7%. The Beta Blockers segment is also set to grow at 3.0% CAGR over the analysis period.
• Regional Analysis: Gain insights into the U.S. market, valued at $108.4 Million in 2024, and China, forecasted to grow at an impressive 6.4% CAGR to reach $97.1 Million by 2030. Discover growth trends in other key regions, including Japan, Canada, Germany, and the Asia-Pacific.

Why You Should Buy This Report:

• Detailed Market Analysis: Access a thorough analysis of the Global Graves' Disease (Overactive Thyroid) Market, covering all major geographic regions and market segments.
• Competitive Insights: Get an overview of the competitive landscape, including the market presence of major players across different geographies.
• Future Trends and Drivers: Understand the key trends and drivers shaping the future of the Global Graves' Disease (Overactive Thyroid) Market.
• Actionable Insights: Benefit from actionable insights that can help you identify new revenue opportunities and make strategic business decisions.

Key Questions Answered:

• How is the Global Graves' Disease (Overactive Thyroid) Market expected to evolve by 2030?
• What are the main drivers and restraints affecting the market?
• Which market segments will grow the most over the forecast period?
• How will market shares for different regions and segments change by 2030?
• Who are the leading players in the market, and what are their prospects?

Report Features:

• Comprehensive Market Data: Independent analysis of annual sales and market forecasts in US$ Million from 2024 to 2030.
• In-Depth Regional Analysis: Detailed insights into key markets, including the U.S., China, Japan, Canada, Europe, Asia-Pacific, Latin America, Middle East, and Africa.
• Company Profiles: Coverage of players such as Abbott Laboratories, Apitope International NV, bioMérieux SA, Crinetics Pharmaceuticals, and more.
• Complimentary Updates: Receive free report updates for one year to keep you informed of the latest market developments.

Some of the 47 companies featured in this Graves' Disease (Overactive Thyroid) market report include:

• Abbott Laboratories
• Apitope International NV
• bioMérieux SA
• Crinetics Pharmaceuticals
• F. Hoffmann-La Roche Ltd
• HanAll Biopharma
• Horizon Therapeutics (Amgen Inc.)
• Immunovant, Inc.
• Institute of Isotopes Co., Ltd.
• Jubilant Pharma Holdings Inc.
• Merck KGaA
• Novartis AG
• Pfizer Inc.
• Sanofi
• Sling Therapeutics
• Sun Pharmaceutical Industries Ltd.
• Teva Pharmaceutical Industries Ltd.
• Thermo Fisher Scientific Inc.
• Tourmaline Bio
• Viridian Therapeutics

This edition integrates the latest global trade and economic shifts as of June 2025 into comprehensive market analysis. Key updates include:

• Tariff and Trade Impact: Insights into global tariff negotiations across 180+ countries, with analysis of supply chain turbulence, sourcing disruptions, and geographic realignment. Special focus on 2025 as a pivotal year for trade tensions, including updated perspectives on the Trump-era tariffs.
• Adjusted Forecasts and Analytics: Revised global and regional market forecasts through 2030, incorporating tariff effects, economic uncertainty, and structural changes in globalization. Includes segmentation by product, technology, type, material, distribution channel, application, and end-use, with historical analysis since 2015.
• Strategic Market Dynamics: Evaluation of revised market prospects, regional outlooks, and key economic indicators such as population and urbanization trends.
• Innovation & Technology Trends: Latest developments in product and process innovation, emerging technologies, and key industry drivers shaping the competitive landscape.
• Competitive Intelligence: Updated global market share estimates for 2025, competitive positioning of major players (Strong/Active/Niche/Trivial), and refined focus on leading global brands and core players.
• Expert Insight & Commentary: Strategic analysis from economists, trade experts, and domain specialists to contextualize market shifts and identify emerging opportunities.
• Complimentary Update: Buyers receive a free July 2025 update with finalized tariff impacts, new trade agreement effects, revised projections, and expanded country-level coverage.