Lamellar Ichthyosis Epidemiology Forecast 2025-2034

The lamellar ichthyosis epidemiological forecast indicates that lamellar ichthyosis is a common form of autosomal recessive congenital ichthyosis. The prevalence of lamellar ichthyosis in Europe is estimated to be between 1 in 100,000 and 1 in 300,000 individuals, as per the Orphanet. In the United States, the incidence of lamellar ichthyosis is between 5 and 10 cases per 100,000 individuals, according to a 2024 review article. Further, studies show that the condition equally affects both sexes and occurs across all racial and ethnic groups.

Lamellar Ichthyosis Epidemiology Forecast Report Coverage

The “Lamellar Ichthyosis Epidemiology Forecast Report 2025-2034” offers comprehensive information on the prevalence and demographics of lamellar ichthyosis. It projects the future incidence and prevalence rates of lamellar ichthyosis cases across various populations. The study covers age and type as major determinants of the lamellar ichthyosis population. The report highlights patterns in the prevalence of lamellar ichthyosis over time and projects future trends based on multiple variables.

The report provides a comprehensive overview of the disease, as well as historical and projected data on lamellar ichthyosis epidemiology in the 8 major markets.

Regions Covered

• The United States
• Germany
• France
• Italy
• Spain
• The United Kingdom
• Japan
• India

Lamellar Ichthyosis Understanding: Disease Overview

Lamellar ichthyosis refers to a rare genetic skin disorder that affects the body's ability to shed dead skin cells. It is characterized by the buildup of thick, dry, and scaly skin and is considered one of the most severe forms of ichthyosis. The condition usually appears at birth or shortly after, and its severity can vary from person to person.

Lamellar Ichthyosis is inherited in an autosomal recessive pattern. It is caused by mutations in the TGM1 gene, which plays a role in the skin’s ability to form its outer protective layer. Lamellar ichthyosis patients also experience complications such as vision problems, hearing loss, and excessive sweating (hyperhidrosis), among others.

Lamellar Ichthyosis Epidemiology Perspective

The lamellar ichthyosis epidemiology division offers information on the patient pool from history to the present as well as the projected trend for each of the 8 major markets. The publisher provides both current and predicted trends for lamellar ichthyosis epidemiology scenario by examining a wide range of studies. Additionally, the report covers the diagnosed patient pool for the disease and their trends. The lamellar ichthyosis detailed epidemiology segmentation is broken down into specific categories, such as the total diagnosed cases across different age groups and patient pools.

• According to Orphanet, lamellar ichthyosis is the most common form of autosomal recessive congenital ichthyosis (ARCI), with the prevalence in Europe estimated to be between 1 in 100,000 and 1 in 300,000 individuals.
• As per Maritska, Ziske, et al. (2024), lamellar ichthyosis affects about 1 in 200,000 people. This condition does not discriminate by sex, race, or ethnicity, and can occur in individuals from any racial or ethnic group.
• Ichthyosis is reported to affect 5 to 10 people per 100,000 worldwide, with lamellar ichthyosis (LI) being a significant form of autosomal recessive congenital ichthyosis. Moreover, lamellar ichthyosis is considered a major type of inherited ichthyosis that typically occurs in a nonsyndromic form.
• Studies show that lamellar ichthyosis affects all populations, with a prevalence of less than 1 case per 300,000 individuals. The condition affects both males and females equally. Lamellar ichthyosis is present at birth and persists throughout life.

Country-wise Lamellar Ichthyosis Epidemiology Segment

The lamellar ichthyosis epidemiology data and findings for the United States, Germany, Spain, Italy, France, the United Kingdom, Japan, and India are also provided in the epidemiology section.

The epidemiology of lamellar ichthyosis varies significantly between countries due to differences in factors such as genetic predispositions, healthcare access, and diagnostic practices. Populations with higher rates of consanguinity (marriage between close relatives) are likely to have a higher incidence of lamellar ichthyosis, as it is inherited in an autosomal recessive pattern. In the United States, the incidence of lamellar ichthyosis is between 5 and 10 cases per 100,000 individuals, according to a 2024 review article.

Lamellar Ichthyosis: Treatment Overview

Lamellar ichthyosis therapeutics aim to keep the skin hydrated, reduce scaling, and prevent infections. Topical retinoids like tretinoin are often prescribed to normalize skin shedding. In severe lamellar ichthyosis cases, oral retinoids, such as acitretin, are recommended to reduce skin thickness.

Topical antibiotics or antifungal treatments are used to prevent infections. Lamellar ichthyosis patients with eye complications may need artificial tears or lubricating drops to prevent dryness and irritation. For those experiencing hyperhidrosis, antiperspirants or oral medications can be used to manage excessive sweating.

Key Questions Answered

• What are the key findings of lamellar ichthyosis epidemiology in the 8 major markets?
• What will be the total number of patients with lamellar ichthyosis across the 8 major markets during the forecast period?
• What was the country-wise lamellar ichthyosis epidemiology scenario in the 8 major markets in the historical period?
• Which country will have the highest number of lamellar ichthyosis patients during the forecast period of 2025-2034?
• Which key factors would influence the shift in the patient population of lamellar ichthyosis during the forecast period of 2025-2034?
• What are the currently available treatments in the lamellar ichthyosis market?
• What are the disease risks, signs, symptoms, and unmet needs of lamellar ichthyosis?

Scope of the Lamellar Ichthyosis Epidemiology Report

• The report covers a detailed analysis of signs and symptoms, causes, risk factors, pathophysiology, diagnosis, treatment options, and classification/types of lamellar ichthyosis based on several factors.
• The Lamellar Ichthyosis Epidemiology Forecast Report covers data for the eight major markets (the US, France, Germany, Italy, Spain, the UK, Japan, and India).
• The lamellar ichthyosis report helps to identify the patient population, and the unmet needs are highlighted along with an assessment of the disease's risk and burden.

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