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Avascular Necrosis Epidemiology Forecast 2025-2034

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    Report

  • 150 Pages
  • June 2025
  • Region: Global
  • Expert Market Research
  • ID: 6102606
Avascular necrosis is a painful bone disease that leads to bone tissue death. The condition commonly affects the hip. Studies show that around 15,000 new cases of avascular necrosis are reported annually in the United States, with 10% of the total hip replacement surgeries occurring on account of avascular necrosis.

Avascular Necrosis Epidemiology Forecast Report Coverage

The “Avascular Necrosis Epidemiology Forecast Report 2025-2034” offers comprehensive information on the prevalence and demographics of avascular necrosis. It projects the future incidence and prevalence rates of avascular necrosis across various populations. The study covers age and type as major determinants of the avascular necrosis-affected population. The report highlights patterns in the prevalence of avascular necrosis over time and projects future trends based on multiple variables.

The report provides a comprehensive overview of the disease, as well as historical and projected data on the epidemiology of avascular necrosis in the 8 major markets.

Regions Covered

  • The United States
  • Germany
  • France
  • Italy
  • Spain
  • The United Kingdom
  • Japan
  • India

Avascular Necrosis: Disease Overview

Avascular necrosis, also known as osteonecrosis or bone infarction, is characterized by the death of bone tissue. It occurs due to the permanent or temporary loss of blood supply to the bone. Although avascular necrosis can affect any bone, it primarily occurs in the ends of long bone. Common symptoms include limited range of motion, intermittent pain, increasing pain and stiff joints, and limping, among others.

Avascular Necrosis: Treatment Overview

The treatment plan for avascular necrosis depends on the severity and location of the disease along with the patient’s profile (age and general health). Anti-inflammatory drugs (NSAIDs) are commonly used for pain relief. Limited weight bearing with crutches or immobilization may help in certain cases. However, in advanced avascular necrosis cases, the patient often needs surgery as the disease course is unaffected by activity.

Epidemiology

The avascular necrosis epidemiology section offers information on the patient pool from history to the present as well as the projected trend for each of the 8 major markets. The publisher provides both current and predicted trends for avascular necrosis by examining a wide range of studies. Additionally, the report covers the diagnosed patient pool for avascular necrosis and their trends. The data is broken down into specific categories, such as the total diagnosed cases across different age groups and patient pools.
  • In the United States, it is estimated that 15,000 new cases of avascular necrosis occur annually. Moreover, this degenerative bone disease is responsible for 10% of total hip replacement surgeries performed in the country.
  • Avascular necrosis usually affects people between the ages of 30 to 65.
  • Studies report that men tend to be more affected by the condition compared to women, showing an overall male-to-female ratio of 8:1.
  • As per Lamb, Jonathan N et al. (2019), in the United Kingdom, avascular necrosis is reported as the third most common cause of total hip replacement in the patient population under 50 years of age.

Country-wise Avascular Necrosis Epidemiology

The avascular necrosis epidemiology data and findings for the United States, EU-4 (Germany, Spain, Italy, France), the United Kingdom, Japan, and India are also provided in the epidemiology section.

The epidemiology of avascular necrosis varies significantly between countries owing to the differences in the prevalence of risk factors (such as alcohol abuse, corticosteroid use, and metabolic disorders), genetic predisposition, and access to healthcare, among others. In many Asian countries, like India, avascular necrosis is highly prevalent and ranks as one of the leading indications for total hip arthroplasty (THA). According to a study published in the Journal of Orthopaedics (2022), avascular necrosis is the most common indication for total hip arthroplasty in India (approximately 52%).

Scope of the Report

  • The report covers a detailed analysis of signs and symptoms, causes, risk factors, pathophysiology, diagnosis, treatment options, and classification/types of avascular necrosis based on several factors.
  • Avascular Necrosis Epidemiology Forecast Report covers data for the eight major markets (the US, France, Germany, Italy, Spain, the UK, Japan, and India).
  • The report helps to identify the patient population, and the unmet needs of avascular necrosis are highlighted along with an assessment of the disease's risk and burden.

Key Questions Answered

  • What are the key findings of avascular necrosis epidemiology in the 8 major markets?
  • What will be the total number of patients with avascular necrosis across the 8 major markets during the forecast period?
  • What was the country-wise prevalence of avascular necrosis in the 8 major markets in the historical period?
  • Which country will have the highest number of avascular necrosis patients during the forecast period of 2025-2034?
  • Which key factors would influence the shift in the patient population of avascular necrosis during the forecast period of 2025-2034?
  • What are the currently available treatments for avascular necrosis?
  • What are the disease risks, signs, symptoms, and unmet needs of avascular necrosis?

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Table of Contents

1 Preface
1.1 Introduction
1.2 Objectives of the Study
1.3 Research Methodology and Assumptions
2 Executive Summary
3 Avascular Necrosis Market Overview - 8 MM
3.1 Avascular Necrosis Market Historical Value (2018-2024)
3.2 Avascular Necrosis Market Forecast Value (2025-2034)
4 Avascular Necrosis Epidemiology Overview - 8 MM
4.1 Avascular Necrosis Epidemiology Scenario (2018-2024)
4.2 Avascular Necrosis Epidemiology Forecast
5 Disease Overview
5.1 Signs and Symptoms
5.2 Causes
5.3 Risk Factors
5.4 Guidelines and Stages
5.5 Pathophysiology
5.6 Screening and Diagnosis
5.7 Types of Avascular Necrosis
6 Patient Profile
6.1 Patient Profile Overview
6.2 Patient Psychology and Emotional Impact Factors
7 Epidemiology Scenario and Forecast - 8 MM
7.1 Key Findings
7.2 Assumptions and Rationale
7.3 Avascular Necrosis Epidemiology Scenario in 8MM (2018-2034)
8 Epidemiology Scenario and Forecast: United States
8.1 Avascular Necrosis Epidemiology Scenario and Forecast in the United States (2018-2034)
9 Epidemiology Scenario and Forecast: EU-4 and United Kingdom
9.1 Avascular Necrosis Epidemiology Scenario and Forecast in EU-4 and United Kingdom (2018-2034)
9.2 United Kingdom
9.2.1 Avascular Necrosis Epidemiology Scenario and Forecast in United Kingdom (2018-2034)
9.3 Germany
9.3.1 Avascular Necrosis Epidemiology Scenario and Forecast in Germany (2018-2034)
9.4 France
9.4.1 Avascular Necrosis Epidemiology Scenario and Forecast in France
9.5 Italy
9.5.1 Avascular Necrosis Epidemiology Scenario and Forecast in Italy (2018-2034)
9.6 Spain
9.6.1 Avascular Necrosis Epidemiology Scenario and Forecast in Spain (2018-2034)
10 Epidemiology Scenario and Forecast: Japan
10.1 Avascular Necrosis Epidemiology Scenario and Forecast in Japan (2018-2034)
11 Epidemiology Scenario and Forecast: India
11.1 Avascular Necrosis Epidemiology Scenario and Forecast in India (2018-2034)
12 Patient Journey13 Treatment Challenges and Unmet Needs14 Key Opinion Leaders (KOL) Insights