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Seizures Drug Pipeline Analysis Report 2025

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    Report

  • 200 Pages
  • June 2025
  • Region: Global
  • Expert Market Research
  • ID: 6102690
According to the World Health Organization, approximately 50 million people have epilepsy globally. It is one of the most common neurological diseases. As per data suggested by the Centers for Disease Control and Prevention, in the United States, 3 million people suffer from epilepsy. There has been a significant emphasis on developing effective seizure therapeutic products for neurological disorders as major companies and institutions are working towards innovative treatments for seizures.

Report Coverage

The Seizures Drug Pipeline Report by the publisher gives comprehensive insights into seizures drugs currently undergoing clinical trials. It covers various aspects related to the details of each of these drugs under development for seizures. The seizures report includes the analysis of over 100 pipeline drugs and 50+ companies. It will include an analysis based on efficacy and safety measure outcomes published for the trials including their adverse effects on patients suffering from seizures.

The detailed seizures analytical perspective of each drug, drug class, clinical studies, phase type, drug type, route of administration and ongoing product development activities related to seizures are covered.

Seizures Drug Pipeline Outlook

A seizure is a sudden and uncontrolled burst of electrical activity in the brain, which can cause changes in movements, behavior, and levels of consciousness. It can occur after a head injury or a stroke and be caused by an infection such as meningitis. There are multiple types of seizures. The type of seizure varies from where they begin in the brain. The frequency of most seizures lasts from 30 seconds to two minutes. The symptoms of seizure include temporary confusion, staring spells, jerking movements of the legs and arms, loss of consciousness or awareness, and cognitive changes.

Seizures treatment includes the use of anti-seizure medicines. Different options for anti-seizure medicine are available in the market. Companies are developing innovative treatments to manage seizures. For instance, a phase III clinical trial study is being conducted to assess the effects of ZX008 when used as adjunctive therapy for the treatment of seizures. Several seizure therapeutic products in the pipeline are being developed by major pharma companies which has impacted the pipeline analysis for seizures.

Seizures - Drug Pipeline Therapeutic Assessment

This section of the seizures report covers the analysis of seizure drugs based on various segmentations such as:

By Phase

The pipeline assessment report covers 50+ drug analyses based on phase.
  • Late-Stage Products (Phase 3 and Phase 4)
  • Mid-Stage Products (Phase 2)
  • Early-Stage Products (Phase I)
  • Preclinical and Discovery Stage Products

By Drug Class

The seizures clinical assessment of products covers 50+ drug analyses based on drug classes:

  • Sodium Channel Blockers
  • Calcium Channel Blockers
  • Gamma-Aminobutyric Acid (GABA)
  • Enhancers Glutamate Receptor Antagonists

By Route of Administration

The seizures clinical assessment covers 50+ drug analyses based on the route of administration.
  • Oral
  • Parenteral
  • Others

Seizures - Pipeline Assessment Segmentation, By Phases

The seizures pipeline insight covers phase I, phase II, phase III, phase IV, and early phase drugs. The coverage includes an in-depth analysis of each drug across these phases. According to analysis, phase III covers a major share of the total clinical trials, with approximately 300 trials are currently in phase III.

Seizures - Pipeline Assessment Segmentation, By Drug Class

The drug class categories covered under seizure pipeline analysis include sodium channel blockers, calcium channel blockers, gamma-aminobutyric acid (GABA), enhancers glutamate receptor antagonists. Sodium channel blockers inhibit voltage-gated sodium channels help in reducing neuronal excitability and prevent the spread of seizure. The report provides a comparative analysis of the drug classes for each drug in various phases of clinical trials for seizures.

Seizures Clinical Trials Assessment - Competitive Dynamics

The report for the seizures pipeline landscape covers the profile of key companies involved in clinical trials and their drugs under development. Below is the list of a few players involved in seizures clinical trials:
  • GSK PLC
  • Eisai Co., Ltd.
  • Novartis AG
  • Johnson & Johnson Pharmaceutical Research & Development, L.L.C.
  • Neurelis, Inc.
  • Others

Seizures - Pipeline Drugs Profile

Cannabidiol Oral Solution

Cannabidiol oral solution is currently under phase II and is sponsored by INSYS Therapeutics Inc. The study is being conducted to assess the safety and tolerability of three multiple ascending doses of cannabidiol oral solution in patients.

RWJ-333369

A phase III study, sponsored by SK Life Science, Inc. is evaluating the safety and effectiveness of the drug to manage partial epilepsy in patients who have poor seizure control.

Retigabine

GlaxoSmithKline is developing the drug and it is currently under phase III. The study is investigating the safety and efficacy of seizures treatment retigabine dosed at 900 mg/day and 600 mg/day in epilepsy patients.

Reasons To Buy This Report

The Seizures Drug Pipeline Analysis Report provides a strategic overview of the latest and future landscape of treatments for seizures. It provides necessary information for making informed investment decisions along with research, development, and strategic planning efforts. The stakeholders will benefit from the essential insights into seizures collaborations, market trends, regulatory environments, and potential growth opportunities within seizure drug pipeline insights.

Key Questions Answered in the Seizures - Pipeline Assessment Report

  • What is the current landscape of Seizures pipeline drugs?
  • Which companies/institutions are developing Seizures emerging drugs?
  • How many phase II drugs are currently present in Seizures pipeline drugs?
  • Which company is leading the Seizures pipeline development activities?
  • What is the current Seizures therapeutic assessment?
  • What are the opportunities and challenges present in the Seizures drug pipeline landscape?
  • What is the efficacy and safety profile of Seizures pipeline drugs?
  • Which companies/institutions are involved in Seizures collaborations aimed at providing enhanced therapeutic alternatives for patients?
  • What are the geographies covered for clinical trials in Seizures?

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Table of Contents

1 Preface
1.1 Introduction
1.2 Objectives of the Study
1.3 Research Methodology and Assumptions
2 Executive Summary
3 Overview of Seizures
3.1 Signs and Symptoms
3.2 Causes
3.3 Risk Factors
3.4 Diagnosis
3.5 Treatment
4 Patient Profile
4.1 Patient Profile Overview
4.2 Patient Psychology and Emotional Impact Factors
4.3 Risk Assessment and Treatment Success Rate
5 Seizures: Epidemiology Snapshot
5.1 Seizures Incidence by Key Markets
5.2 Seizures- Patients Seeking Treatment in Key Markets
6 Seizures: Market Dynamics
6.1 Market Drivers and Constraints
6.2 SWOT Analysis
7 Seizures: Key Facts Covered
7.1 Top Countries Contributing to Clinical Trials in Asia-Pacific
7.2 Top Countries Contributing to Clinical Trials in Europe
7.3 Top Countries Contributing to Clinical Trials in North America
7.4 Top Countries Contributing to Clinical Trials in Other Regions
8 Seizures, Drug Pipeline Assessment
8.1 Assessment by Treatment Type
8.2 Assessment by Route of Administration
8.3 Assessment by Drug Class
9 Drug Pipeline Comparative Analysis
9.1 List of Seizures Pipeline Drugs
9.1.1 By Company
9.1.2 By Phase
9.1.3 By Indication
9.1.4 By Trial Status
9.1.5 By Funder Type
9.2 Attribute Scoring Analysis of Pipeline Drugs (Top Drugs)
10 Seizures Drug Pipeline - Late-Stage Products (Phase III and IV) (Top Drugs)
10.1 Comparative Analysis for Late-Stage Drugs
10.1.1 Study Type
10.1.2 Recruitment Status
10.1.3 Company
10.1.4 Funder Type
10.2 Product Level Analysis*
10.2.1 Buccal Midazolam
10.2.1.1 Product Description
10.2.1.2 Trial ID
10.2.1.3 Sponsor Name
10.2.1.4 Study Type
10.2.1.5 Drug Class
10.2.1.6 Eligibility Criteria
10.2.1.7 Study Record Dates
10.2.1.7.1 First Submitted
10.2.1.7.2 First Posted
10.2.1.7.3 Last Update Posted
10.2.1.7.4 Last Verified
10.2.1.8 Indication
10.2.1.9 Study Design
10.2.1.10 Recruitment Status
10.2.1.11 Enrollment (Estimated)
10.2.1.12 Location Countries
10.2.1.13 Recent Results
10.2.2 Carbamazepine
10.2.3 Pregabalin
10.2.4 Other Drug
11 Seizures Drug Pipeline - Mid-Stage Products (Phase II) (Top Drugs)
11.1 Comparative Analysis for Mid-Stage Drugs
11.1.1 Study Type
11.1.2 Recruitment Status
11.1.3 Company
11.1.4 Funder Type
11.2 Product Level Analysis*
11.2.1 CVL-865
11.2.1.1 Product Description
11.2.1.2 Trial ID
11.2.1.3 Sponsor Name
11.2.1.4 Study Type
11.2.1.5 Drug Class
11.2.1.6 Eligibility Criteria
11.2.1.7 Study Record Dates
11.2.1.7.1 First Submitted
11.2.1.7.2 First Posted
11.2.1.7.3 Last Update Posted
11.2.1.7.4 Last Verified
11.2.1.8 Indication
11.2.1.9 Study Design
11.2.1.10 Recruitment Status
11.2.1.11 Enrollment (Estimated)
11.2.1.12 Location Countries
11.2.1.13 Recent Results
11.2.2 Perampanel
11.2.3 Other Drugs
12 Seizures Drug Pipeline - Early-Stage Products (Phase I) (Top Drugs)
12.1 Comparative Analysis for Early-Stage Drugs
12.1.1 Study Type
12.1.2 Recruitment Status
12.1.3 Company
12.1.4 Funder Type
12.2 Product Level Analysis*
12.2.1 Topiramate
12.2.1.1 Product Description
12.2.1.2 Trial ID
12.2.1.3 Sponsor Name
12.2.1.4 Study Type
12.2.1.5 Drug Class
12.2.1.6 Eligibility Criteria
12.2.1.7 Study Record Dates
12.2.1.7.1 First Submitted
12.2.1.7.2 First Posted
12.2.1.7.3 Last Update Posted
12.2.1.7.4 Last Verified
12.2.1.8 Indication
12.2.1.9 Study Design
12.2.1.10 Recruitment Status
12.2.1.11 Enrollment (Estimated)
12.2.1.12 Location Countries
12.2.2 Oxcarbazepine
12.2.3 Divalproex Sodium
12.2.4 Other Drugs
13 Seizures Drug Pipeline - Preclinical and Discovery Stage Products (Top Drugs)
13.1 Comparative Analysis for Preclinical and Discovery Stage Drugs
13.1.1 Study Type
13.1.2 Recruitment Status
13.1.3 Company
13.1.4 Funder Type
13.2 Product Level Analysis*
13.2.1 Drug 1
13.2.1.1 Product Description
13.2.1.2 Trial ID
13.2.1.3 Sponsor Name
13.2.1.4 Study Type
13.2.1.5 Drug Class
13.2.1.6 Eligibility Criteria
13.2.1.7 Study Record Dates
13.2.1.7.1 First Submitted
13.2.1.7.2 First Posted
13.2.1.7.3 Last Update Posted
13.2.1.7.4 Last Verified
13.2.1.8 Indication
13.2.1.9 Study Design
13.2.1.10 Recruitment Status
13.2.1.11 Enrollment (Estimated)
13.2.1.12 Location Countries
13.2.2 Drug 2
13.2.3 Other Drugs
14 Seizures, Key Drug Pipeline Companies
14.1 GSK PLC
14.1.1 Company Snapshot
14.1.2 Pipeline Product Portfolio
14.1.3 Financial Analysis
14.1.4 Recent News and Developments
14.2 Eisai Co., Ltd.
14.2.1 Company Snapshot
14.2.2 Pipeline Product Portfolio
14.2.3 Financial Analysis
14.2.4 Recent News and Developments
14.3 Novartis AG
14.3.1 Company Snapshot
14.3.2 Pipeline Product Portfolio
14.3.3 Financial Analysis
14.3.4 Recent News and Developments
14.4 Johnson & Johnson Pharmaceutical Research & Development, L.L.C.
14.4.1 Company Snapshot
14.4.2 Pipeline Product Portfolio
14.4.3 Financial Analysis
14.4.4 Recent News and Developments
14.5 Neurelis, Inc.
14.5.1 Company Snapshot
14.5.2 Pipeline Product Portfolio
14.5.3 Financial Analysis
14.5.4 Recent News and Developments
15 Regulatory Framework for Drug Approval, By Region16 Terminated or Suspended Pipeline Products