+353-1-416-8900REST OF WORLD
+44-20-3973-8888REST OF WORLD
1-917-300-0470EAST COAST U.S
1-800-526-8630U.S. (TOLL FREE)
New

Human Immunodeficiency Virus (HIV 1) Infection Pipeline Analysis Report 2025

  • PDF Icon

    Report

  • 200 Pages
  • June 2025
  • Region: Global
  • Expert Market Research
  • ID: 6102782
According to the World Health Organization, 39.9 million people were living with HIV globally in 2023. Out of this, 38.6 million were adults and 53% of the infected people were women and girls. Studies suggest that approximately 5.4 million people aren’t aware that they have HIV. The common treatment for human immunodeficiency virus infection includes antiretroviral therapy (ART). This therapy involves taking a combination of HIV medicines every day. Several clinical trials are ongoing to develop innovative human immunodeficiency virus (HIV 1) infection therapeutics to improve and manage the condition including islatravir, and fostemsavir among others.

Report Coverage

The Human Immunodeficiency Virus (HIV 1) Infection Pipeline Report by the publisher gives comprehensive insights into Human Immunodeficiency Virus (HIV 1) Infection drugs currently undergoing clinical trials. It covers various aspects related to the details of each of these drugs under development for human immunodeficiency virus (HIV 1) infection. The human immunodeficiency virus (HIV 1) infection pipeline insight includes the analysis of over 100 pipeline drugs and 50+ companies . It will include an analysis based on efficacy and safety measure outcomes published for the trials including their adverse effects on patients suffering from human immunodeficiency virus (HIV 1) infection.

The detailed analysis of each drug, drug class, clinical studies, phase type, drug type, route of administration and ongoing human immunodeficiency virus (HIV 1) infection development activities is covered in the report.

Human Immunodeficiency Virus (HIV 1) Infection Drug Pipeline Outlook

HIV stands for human immunodeficiency virus, which infects cells of the immune system and makes the body weak to fight against various diseases. When HIV has severely weakened the immune system, it can lead to AIDS (acquired immunodeficiency syndrome). Human immunodeficiency virus infects the white blood cells of the immune system called CD4 cells, destroys them and causes a drop in the white blood cell count. At an initial level, HIV makes the infected person sick with flu-like symptoms and hides in the body for a long without any noticeable symptoms. The virus slowly destroys the T-cells at this phase. When numbers of T-cells get very low, it indicates that HIV has progressed to AIDS.

Currently, there is no cure for HIV. However, there are several human immunodeficiency virus (HIV 1) infection therapeutic drugs available to slow down the progression of HIV. The infection is treated with a combination of medicines, administered orally every day. Taking a combination of medicines is the most effective way to keep HIV from multiplying and destroying the cells. There are several types of ART including nucleoside reverse transcriptase inhibitors, protease inhibitors, fusion inhibitors, pharmacokinetic enhancers, integrase strand transfer inhibitors, and non-nucleoside reverse transcriptase inhibitors among others. As HIV infection is a major health issue, the development of new human immunodeficiency virus (HIV 1) infection drug candidates is crucial for the management of the disease. The focus areas of clinical trials include antiretroviral therapies and vaccines among others. For instance, Vir Biotechnology, Inc. is evaluating the safety of prototype human CMV-based vaccine to manage human immunodeficiency virus infection. These dynamics are impacting the clinical trial landscape significantly.

Human Immunodeficiency Virus (HIV 1) Infection - Drug Pipeline Therapeutic Assessment

This section of the report covers the analysis of human immunodeficiency virus (HIV 1) infection emerging drugs based on several segmentations including:

By Phase

The pipeline assessment report covers 50+ drug analyses based on phase.
  • Late-Stage Products (Phase 3 and Phase 4)
  • Mid-Stage Products (Phase 2)
  • Early-Stage Products (Phase I)
  • Preclinical and Discovery Stage Products

By Drug Class

The human immunodeficiency virus (HIV 1) infection therapeutic assessment covers 50+ drug analyses based on drug classes:

  • Monoclonal Antibody
  • Peptides
  • Small Molecule

By Route of Administration

The human immunodeficiency virus (HIV 1) infection clinical assessment report covers 50+ drug analyses based on the route of administration.
  • Oral
  • Parenteral
  • Others

Human Immunodeficiency Virus (HIV 1) Infection - Pipeline Assessment Segmentation, By Phases

The human immunodeficiency virus (HIV 1) infection report assessment covers phase I, phase II, phase III, phase IV, and early phase drugs. The coverage includes an in-depth analysis of each drug across these phases. According to analysis, phase I covers a major share of the total clinical trials for human immunodeficiency virus.

Human Immunodeficiency Virus (HIV 1) Infection - Pipeline Assessment Segmentation, By Drug Classes

The drug molecules categories covered under human immunodeficiency virus (HIV 1) infection pipeline analysis include monoclonal antibodies, peptides, and small molecules. International AIDS Vaccine Initiative is currently evaluating the safety of PGT121 monoclonal antibody for HIV prevention and therapy. The report provides a comparative analysis of the drug classes for each drug in various phases of clinical trials for human immunodeficiency virus (HIV 1) infection.

Human Immunodeficiency Virus (HIV 1) Infection Clinical Trials Assessment - Competitive Dynamics

The human immunodeficiency virus (HIV 1) infection report insights cover the profile of key companies involved in clinical trials and their drugs under development. Below is the list of a few players involved in human immunodeficiency virus (HIV 1) infection clinical trials:
  • Tibotec Pharmaceuticals
  • Vir Biotechnology, Inc.
  • Janssen Research & Development, LLC
  • ViiV Healthcare
  • Janssen-Cilag S.p.A.
  • Seagen Inc.
  • Merck Sharp & Dohme LLC
  • Johnson & Johnson Pte Ltd
  • Sangamo Therapeutics
  • TaiMed Biologics Inc.
  • AbbVie
  • Gilead Sciences
  • Alexion Pharmaceuticals, Inc.
  • Abbott
  • Others

Tibotec Pharmaceuticals

Vir Biotechnology, Inc.

Janssen Research & Development, LLC

ViiV Healthcare

Janssen-Cilag S.p.A.

Seagen Inc.

Merck Sharp & Dohme LLC

Johnson & Johnson Pte Ltd

Sangamo Therapeutics

TaiMed Biologics Inc.

AbbVie

Gilead Sciences

Alexion Pharmaceuticals, Inc.

Abbott

Others

Human Immunodeficiency Virus (HIV 1) Infection - Emerging Drugs Profile

This section covers the detailed analysis of each drug under multiple phases including phase I, phase II, phase III, phase IV, and human immunodeficiency virus (HIV 1) infection therapeutic drugs. It covers necessary details such as product description, study type, drug class, mode of administration, and recruitment status of upcoming human immunodeficiency virus (HIV 1) infection drug candidates.

Drug: ABBV-181

The trial is designed to test the safety of pharmacokinetics and pharmacodynamics of ABBV-181, a drug designed for human immunodeficiency virus-1 infected participants who are taking antiretroviral therapy. The trial is sponsored by AbbVie and is currently under phase I.

Drug: Doravirine, Tenofovir, Lamivudine

The objective of the study is to compare the antiretroviral activity of three drugs, namely, oravirine, tenofovir, and lamivudine in participants infected with the human immunodeficiency virus. The trial is sponsored by Merck Sharp & Dohme LLC and is currently under phase III.

Drug: Cabotegravir

ViiV Healthcare is developing this human immunodeficiency virus (HIV 1) infection drug candidate and is currently under phase III. The study is being conducted to evaluate the safety of the drug in patients receiving CAB and RPV LA injections.

Reasons To Buy This Report

The Human Immunodeficiency Virus (HIV 1) Infection Drug Pipeline Analysis Report provides a strategic overview of the latest and future landscape of treatments for human immunodeficiency virus (HIV 1) infection. It provides necessary information for making informed investment decisions along with research, development, and strategic planning efforts. The stakeholders will benefit from the essential insights into human immunodeficiency virus (HIV 1) infection funding, market trends, regulatory environments, and potential growth opportunities within the human immunodeficiency virus (HIV 1) infection pipeline insights.

Key Questions Answered in the Human Immunodeficiency Virus (HIV 1) Infection - Pipeline Assessment Report

  • What is the current landscape of human immunodeficiency virus (HIV 1) infection disease pipeline drugs?
  • Which companies/institutions are developing human immunodeficiency virus (HIV 1) infection disease emerging drugs?
  • How many phase II drugs are currently present in human immunodeficiency virus (HIV 1) infection disease pipeline drugs?
  • Which company is leading the human immunodeficiency virus (HIV 1) infection disease pipeline development activities?
  • What is the current human immunodeficiency virus (HIV 1) infection disease therapeutic assessment?
  • What are the opportunities and challenges present in the human immunodeficiency virus (HIV 1) infection disease drug pipeline landscape?
  • What is the efficacy and safety profile of human immunodeficiency virus (HIV 1) infection disease pipeline drugs?
  • Which companies/institutions are involved in human immunodeficiency virus (HIV 1) infection disease collaborations aimed at providing enhanced therapeutic alternatives for patients?
  • What are the geographies covered for clinical trials in human immunodeficiency virus (HIV 1) infection disease?

This product will be delivered within 3-5 business days.

Table of Contents

1 Preface
1.1 Introduction
1.2 Objectives of the Study
1.3 Research Methodology and Assumptions
2 Executive Summary
3 Overview of Human Papillomavirus (HPV)
3.1 Signs and Symptoms
3.2 Causes
3.3 Risk Factors
3.4 Diagnosis
3.5 Treatment
4 Patient Profile: Human Papillomavirus (HPV)
4.1 Patient Profile Overview
4.2 Patient Psychology and Emotional Impact Factors
4.3 Risk Assessment and Treatment Success Rate
5 Human Papillomavirus (HPV): Epidemiology Snapshot
5.1 Human Papillomavirus (HPV) Incidence by Key Markets
5.2 Human Papillomavirus (HPV)- Patients Seeking Treatment in Key Markets
6 Human Papillomavirus (HPV): Market Dynamics
6.1 Market Drivers and Constraints
6.2 SWOT Analysis
7 Human Papillomavirus (HPV): Key Facts Covered
7.1 Top Countries Contributing to Clinical Trials in Asia-Pacific
7.2 Top Countries Contributing to Clinical Trials in Europe
7.3 Top Countries Contributing to Clinical Trials in North America
7.4 Top Countries Contributing to Clinical Trials in Other Regions
8 Human Papillomavirus (HPV), Drug Pipeline Assessment
8.1 Assessment by Treatment Type
8.2 Assessment by Route of Administration
8.3 Assessment by Drug Class
9 Drug Pipeline Comparative Analysis
9.1 List of Human Papillomavirus (HPV) Pipeline Drugs
9.1.1 By Company
9.1.2 By Phase
9.1.3 By Indication
9.1.4 By Trial Status
9.1.5 By Funder Type
9.2 Attribute Scoring Analysis of Pipeline Drugs (Top Drugs)
10 Human Papillomavirus (HPV) Drug Pipeline - Late-Stage Products (Phase III and IV) (Top Drugs)
10.1 Comparative Analysis for Late-Stage Drugs
10.1.1 Study Type
10.1.2 Recruitment Status
10.1.3 Company
10.1.4 Funder Type
10.2 Product Level Analysis*
10.2.1 Gardasil 9
10.2.1.1 Product Description
10.2.1.2 Trial ID
10.2.1.3 Sponsor Name
10.2.1.4 Study Type
10.2.1.5 Drug Class
10.2.1.6 Eligibility Criteria
10.2.1.7 Study Record Dates
10.2.1.7.1 First Submitted
10.2.1.7.2 First Posted
10.2.1.7.3 Last Update Posted
10.2.1.7.4 Last Verified
10.2.1.8 Indication
10.2.1.9 Study Design
10.2.1.10 Recruitment Status
10.2.1.11 Enrollment (Estimated)
10.2.1.12 Location Countries
10.2.1.13 Recent Results
10.2.2 Cervarix
10.2.3 Biological: V503
10.2.4 Other Drugs
11 Human Papillomavirus (HPV) Drug Pipeline - Mid-Stage Products (Phase II) (Top Drugs)
11.1 Comparative Analysis for Mid-Stage Drugs
11.1.1 Study Type
11.1.2 Recruitment Status
11.1.3 Company
11.1.4 Funder Type
11.2 Product Level Analysis*
11.2.1 Drug: ABI-2280
11.2.1.1 Product Description
11.2.1.2 Trial ID
11.2.1.3 Sponsor Name
11.2.1.4 Study Type
11.2.1.5 Drug Class
11.2.1.6 Eligibility Criteria
11.2.1.7 Study Record Dates
11.2.1.7.1 First Submitted
11.2.1.7.2 First Posted
11.2.1.7.3 Last Update Posted
11.2.1.7.4 Last Verified
11.2.1.8 Indication
11.2.1.9 Study Design
11.2.1.10 Recruitment Status
11.2.1.11 Enrollment (Estimated)
11.2.1.12 Location Countries
11.2.1.13 Recent Results
11.2.2 Biological: ProCervix
11.2.3 Other Drugs
12 Human Papillomavirus (HPV) Drug Pipeline - Early-Stage Products (Phase I) (Top Drugs)
12.1 Comparative Analysis for Early-Stage Drugs
12.1.1 Study Type
12.1.2 Recruitment Status
12.1.3 Company
12.1.4 Funder Type
12.2 Product Level Analysis*
12.2.1 Drug: ABI-2280
12.2.1.1 Product Description
12.2.1.2 Trial ID
12.2.1.3 Sponsor Name
12.2.1.4 Study Type
12.2.1.5 Drug Class
12.2.1.6 Eligibility Criteria
12.2.1.7 Study Record Dates
12.2.1.7.1 First Submitted
12.2.1.7.2 First Posted
12.2.1.7.3 Last Update Posted
12.2.1.7.4 Last Verified
12.2.1.8 Indication
12.2.1.9 Study Design
12.2.1.10 Recruitment Status
12.2.1.11 Enrollment (Estimated)
12.2.1.12 Location Countries
12.2.2 Drug: TGN-S11
12.2.3 Other Drugs
13 Human Papillomavirus (HPV) Drug Pipeline - Preclinical and Discovery Stage Products (Top Drugs)
13.1 Comparative Analysis for Preclinical and Discovery Stage Drugs
13.1.1 Study Type
13.1.2 Recruitment Status
13.1.3 Company
13.1.4 Funder Type
13.2 Product Level Analysis*
13.2.1 Drug: HB-201 IV
13.2.1.1 Product Description
13.2.1.2 Trial ID
13.2.1.3 Sponsor Name
13.2.1.4 Study Type
13.2.1.5 Drug Class
13.2.1.6 Eligibility Criteria
13.2.1.7 Study Record Dates
13.2.1.7.1 First Submitted
13.2.1.7.2 First Posted
13.2.1.7.3 Last Update Posted
13.2.1.7.4 Last Verified
13.2.1.8 Indication
13.2.1.9 Study Design
13.2.1.10 Recruitment Status
13.2.1.11 Enrollment (Estimated)
13.2.1.12 Location Countries
13.2.2 Other Drugs
14 Human Papillomavirus (HPV), Key Drug Pipeline Companies
14.1 Klein Buendel, Inc.
14.1.1 Company Snapshot
14.1.2 Pipeline Product Portfolio
14.1.3 Financial Analysis
14.1.4 Recent News and Developments
14.2 Inovio Pharmaceuticals
14.2.1 Company Snapshot
14.2.2 Pipeline Product Portfolio
14.2.3 Financial Analysis
14.2.4 Recent News and Developments
14.3 GlaxoSmithKline
14.3.1 Company Snapshot
14.3.2 Pipeline Product Portfolio
14.3.3 Financial Analysis
14.3.4 Recent News and Developments
14.4 Genexine, Inc.
14.4.1 Company Snapshot
14.4.2 Pipeline Product Portfolio
14.4.3 Financial Analysis
14.4.4 Recent News and Developments
14.5 Antiva Biosciences
14.5.1 Company Snapshot
14.5.2 Pipeline Product Portfolio
14.5.3 Financial Analysis
14.5.4 Recent News and Developments
14.6 Xiamen Innovax Biotech Co., Ltd
14.6.1 Company Snapshot
14.6.2 Pipeline Product Portfolio
14.6.3 Financial Analysis
14.6.4 Recent News and Developments
14.7 PT Bio Farma
14.7.1 Company Snapshot
14.7.2 Pipeline Product Portfolio
14.7.3 Financial Analysis
14.7.4 Recent News and Developments
14.8 Wuhan BravoVax Co., Ltd.
14.8.1 Company Snapshot
14.8.2 Pipeline Product Portfolio
14.8.3 Financial Analysis
14.8.4 Recent News and Developments
14.9 Shanghai Zerun Biotechnology Co., Ltd
14.9.1 Company Snapshot
14.9.2 Pipeline Product Portfolio
14.9.3 Financial Analysis
14.9.4 Recent News and Developments
14.10 Hologic Deutschland GmbH
14.10.1 Company Snapshot
14.10.2 Pipeline Product Portfolio
14.10.3 Financial Analysis
14.10.4 Recent News and Developments
14.11 Merck Sharp & Dohme LLC
14.11.1 Company Snapshot
14.11.2 Pipeline Product Portfolio
14.11.3 Financial Analysis
14.11.4 Recent News and Developments
14.12 Gen-Probe, Incorporated
14.12.1 Company Snapshot
14.12.2 Pipeline Product Portfolio
14.12.3 Financial Analysis
14.12.4 Recent News and Developments
14.13 Hoffmann-La Roche
14.13.1 Company Snapshot
14.13.2 Pipeline Product Portfolio
14.13.3 Financial Analysis
14.13.4 Recent News and Developments
14.14 2A Pharma AB
14.14.1 Company Snapshot
14.14.2 Pipeline Product Portfolio
14.14.3 Financial Analysis
14.14.4 Recent News and Developments
14.15 Inovio Pharmaceuticals
14.15.1 Company Snapshot
14.15.2 Pipeline Product Portfolio
14.15.3 Financial Analysis
14.15.4 Recent News and Developments
15 Regulatory Framework for Drug Approval, By Region16 Terminated or Suspended Pipeline Products