Single Use Bioprocessing Market Report and Forecast 2025-2034

The global single use bioprocessing market was valued at USD 17.75 Billion in 2024, driven by increasing adoption of single-use systems across the globe. The market is anticipated to grow at a CAGR of 14.50% during the forecast period of 2025-2034, with the values likely to reach USD 68.75 Billion by 2034.

Single Use Bioprocessing Market Overview

Single-use bioprocessing utilizes disposable, sterilized equipment made from medical-grade plastics, such as bioreactors and mixers, to produce biopharmaceuticals. This offers a cost-effective, flexible alternative to traditional stainless-steel systems, reducing time and resource-intensive cleaning processes. It enhances operational efficiency, cuts maintenance costs, and allows rapid scaling, ideal for clinical trials and personalized medicine. The increasing adoption of single-use systems, particularly after COVID-19, is driving the market as single-use systems accelerate the process as well as improve efficiency. Rising focus on reduced contamination risk and technological advancements are also fueling market demand.

Single Use Bioprocessing Market Growth Drivers

Increasing Adoption of Single-Use Systems is Likely to Boost the Market Growth

The growth of the single-use bioprocessing market is driven by the increased adoption of single-use systems, particularly due to the shift to more flexible, scalable solutions. According to BioPlan’s 21st Annual Report and Survey, single-use systems usage has reached 87%, reflecting a significant shift from traditional stainless-steel systems. These systems offer flexibility, faster setup, and reduced cleaning time, enabling quick production scale-ups, especially in vaccine manufacturing. Additionally, the growing use of single-use bioreactors has encouraged demand for related single-use systems technologies, further fueling market expansion.

Single Use Bioprocessing Market Trends

The market is witnessing several trends and developments to improve the current scenario. Some of the notable trends are as follows:

Shift to Cost-Effective Manufacturing

The market is experiencing a shift towards cost-effective manufacturing due to companies increasingly seeking to reduce production expenses while ensuring quality. Single-use bioprocessing systems reduce capital expenditure associated with traditional bioreactors, reduce facility overhead, and streamline production processes. With the increasing demand for biological products, the cost-effectiveness of disposable equipment and components makes them a more acceptable option.

Growing Demand for Customization

There is a rising trend in the single-use bioprocessing market for customized solutions tailored to specific production needs. This demand for customization is fueled by the increasing complexity of biologics and therapies, such as gene and cell-based treatments, which require specialized techniques. Custom-designed systems enable flexibility and greater control over products, making them essential for meeting the specific requirements of pharmaceutical manufacturers.

Rising Focus on Minimizing Contamination Risk

A key trend in the market is the enhanced focus on reducing contamination risks. Single-use bioprocessing systems eliminate the need for cleaning and sterilization between production batches, mitigating the risk of cross-contamination. With the market's growth, this trend guarantees elevated safety standards in production, rendering single-use technologies very appealing for sensitive processes like vaccines, gene therapy, and monoclonal antibody production.

Increasing Technological Advancements

A prominent trend in the single-use bioprocessing market is the continuous integration of advanced technologies, such as enhanced sensors, automation, and real-time monitoring systems. These innovations are reshaping how bioprocessing is conducted, improving precision, efficiency, and scalability. As a result, single-use systems are becoming more sophisticated, enabling better process control and faster production times.

Single Use Bioprocessing Market Segmentation

The market report offers a detailed analysis of the market based on the following segments:

Market Breakup by Product

• Simple and Peripheral Elements
• Tubing, Filters, Connectors & Transfer Systems
• Bags
• Sampling Systems
• Probes & Sensors
• Others
• Apparatus & Plants
• Bioreactors
• Mixing, Storage & Filling Systems
• Filtration Systems
• Chromatography Systems
• Pumps
• Others
• Work Equipment
• Cell Culture System
• Syringes
• Others

Market Breakup by Workflow

• Upstream Bioprocessing
• Fermentation
• Downstream Bioprocessing

Market Breakup by End User

• Biopharmaceutical Manufactures
• CMOs & CROs
• In-house Manufacturers
• Academic & Clinical Research institutes

Market Breakup by Region

• North America
• Europe
• Asia Pacific
• Latin America
• Middle East and Africa

Single Use Bioprocessing Market Share

Segmentation Based on End User to Witness Substantial Growth

Based on the end user, the market is segmented into biopharmaceutical manufacturers and academic & clinical research institutes. Biopharmaceutical manufacturers are expected to lead the market share due to their increasing demand for efficient, cost-effective, and scalable production processes. Further, the shift towards disposable technologies for drug production and biologics manufacturing, alongside rising investments in biopharmaceutical production, is anticipated to boost the growth of this segment.

Single Use Bioprocessing Market Analysis by Region

The market is divided into regions such as North America, Europe, Asia Pacific, Latin America, and the Middle East and Africa. North America is poised to dominate the market, fueled by its robust pharmaceutical and biomanufacturing sectors, significant R&D efforts, and the rising demand for single-use bioprocessing equipment to facilitate vaccine manufacturing. The presence of organizations such as the Bioprocess Systems Alliance (BPSA) that advocate for single-use technology adoption, enhances the region's growth. In the meantime, the Asia Pacific region is expected to have rapid expansion, driven by increasing bioprocessing investments from international companies and heightened interest from contract manufacturers embracing disposable technology.

Leading Players in the Single Use Bioprocessing Market

The key features of the market report comprise patent analysis, clinical trial analysis, grants analysis, funding and investment analysis, and strategic initiatives by the leading players. The major companies in the market are as follows:

Thermo Fisher Scientific Inc.

Thermo Fisher Scientific is a key player in the single use bioprocessing market, providing innovative sensors, bioreactors, fermentors, and mixing technologies. Their product portfolio includes single-use fermentors and bioreactors that enhance biological manufacturing, improving efficiency and scalability in upstream and downstream workflows. With advanced equipment and services, they focus on accelerating process development and supporting future scaling in biopharmaceutical production.

Sartorius AG

Sartorius AG is a global leader in pharmaceutical and laboratory equipment, specializing in Bioprocess Solutions. Their single-use bioreactors, such as Ambr® 15 and Biostat® STR 2,000 L, are designed for efficient scale-up and high performance in mammalian cell culture. With their Flexsafe® film, the company ensures optimal cell growth and robustness, providing reliable solutions for process development through commercial production phases.

Merck KGaA

Merck, a leading German science, and technology company introduced the Ultimus® single-use process container film in April 2023. This advanced film provides exceptional durability, leak resistance, and ten times greater abrasion resistance than other bioprocessing films. Designed for liquid applications, it enhances operational efficiency, supports healthy cell growth, and addresses common challenges in single use biomanufacturing, ensuring product quality and reliability.

Eppendorf AG

Eppendorf, a German-based company, specializes in premium laboratory solutions and offers scalable bioprocess systems, single-use bioreactors, and software solutions. It offers BioBLU® c single-use bioreactors for animal cell culture and BioBLU® f bioreactors for microbial fermentation. Additionally, the company provides adaptor kits for converting traditional bioreactors to single-use systems and optical pH modules for enhanced bioprocess control in single-use applications.

Other key players in the market include Danaher Corporation, VWR International, LLC, Corning Incorporated, Entegris, Inc., Saint-Gobain Life Sciences, and Rentschler Biopharma SE.

Key Questions Answered in the Single Use Bioprocessing Market Report

• What was the single use bioprocessing market value in 2024?
• What is the single use bioprocessing market forecast outlook for 2025-2034?
• What are the regional markets covered in the report?
• What is the market segmentation based on the product?
• What is the market segmentation based on workflow?
• What is the market breakup based on the end user?
• What major factors aid the demand for single use bioprocessing?
• How has the market performed so far and how is it anticipated to perform in the coming years?
• What are the major drivers, opportunities, and restraints in the market?
• What are the major trends influencing the market?
• Which regional market is expected to dominate the market share in the forecast period?
• Which country is likely to experience elevated growth during the forecast period?
• Who are the key players involved in the single use bioprocessing market?
• What are the current unmet needs and challenges in the market?
• How are partnerships, collaborations, mergers, and acquisitions among the key market players shaping the market dynamics?

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