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Disease-Modifying Therapies for Alzheimer's Disease: Global Markets

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    Report

  • 65 Pages
  • June 2025
  • Region: Global
  • BCC Research
  • ID: 6103016
Currently, the disease-modifying therapies (DMTs) market for Alzheimer’s disease (AD) is in its early stage of development, as the first DMT for AD (lecanemab) was granted full approval by the U.S. FDA in July 2023. Several DMTs are in late-stage (phase 2 and above) clinical trials. If approved, they can expand the AD DMTs market significantly. The publisher estimates market data for 2024 (the base year) and forecasts values for 2025 through 2030. Other than the approved products, the revenue forecast also considers the potential therapeutic candidates expected to enter during the forecast period and their targeted market potential.

The report analyzes the AD DMTs market by target type (anti-amyloid and other emerging targets), drug (Leqembi, Kisunla, and others), molecule type (large and small), and region (Asia-Pacific, North America, Europe, South America, the Middle East, and Africa).

Report Includes
  • Analysis of the current and future global market for disease-modifying therapies for Alzheimer’s disease (AD)
  • Analyses of the global market trends, with market revenue data (sales figures) from 2023 to 2025, forecasts for 2026, and projected CAGRs through 2030
  • Estimates of the market’s size and revenue prospects for the global market, accompanied by a market share analysis based on target type, drug type, drug molecule type, and region
  • Facts and figures pertaining to market dynamics, technological advancements, regulations, prospects, and the impacts of macroeconomic variables
  • Discussion of the underlying opportunities and potential in the disease-modifying therapies market
  • Information on products currently available for the diagnosis and treatment of Alzheimer’s, as well as the promising new drug candidates and diagnostic imaging agents
  • Review of key marketed products, clinical trials, competitive scenario and R&D activities
  • An analysis of emerging trends and the industry structure, including companies’ market shares and rankings, strategic alliances, M&A activity and a venture funding outlook
  • Profiles of the leading companies

Table of Contents

Chapter 1 Executive Summary
  • Market Outlook
  • Scope of Report
  • Market Summary
Chapter 2 Market Overview
  • Alzheimer’s Disease Overview
  • Alzheimer’s Disease Pathophysiology
  • Pharmaceutical Treatment of AD
Chapter 3 Market Dynamics
  • Market Dynamics Snapshot
  • Drivers
  • High Unmet Need in AD Treatment
  • Use of Biomarkers to Accelerate AD DMTs Approvals
  • Challenges
  • High Failure Rate in AD Drug Development
  • High Cost and Side Effects of Approved DMTs
  • Opportunity
  • DMTs for the Preclinical-Stage of AD
Chapter 4 Regulatory Landscape
  • U.S.
  • Standard Drug Approval Process
  • Expedited Approval Pathways
  • DMTs Approval Status by Country/ Region
Chapter 5 Emerging Technologies and Developments
  • A Multi-target Therapeutic Framework
  • Blood Tests for AD Screening and Diagnosis
  • Pipeline Analysis
  • Key Takeaways:
  • Small Molecule DMTs in Phase 3 Clinical Trials
  • Large Molecule DMTs in Phase 3 Clinical Trials
Chapter 6 Market Segment Analysis
  • Segmentation Breakdown
  • Market Analysis, by Target Type
  • Anti-Amyloid
  • Other Emerging Alzheimer's Pathology Targets for DMTs
  • Market Analysis, by Drug
  • Market Analysis, by Drug Molecule Type
  • Large Molecule
  • Small-Molecule
  • Geographic Breakdown
  • Market Analysis by Region
  • North America
  • Asia-Pacific
  • Europe
  • Middle East and Africa
  • South America
Chapter 7 Competitive Intelligence
  • Overview
  • Notable Companies Developing AD DMTs
  • Recent Developments/Strategic Analysis
Chapter 8 Appendix
  • Methodology
  • References
  • Abbreviations
  • Company Profiles
  • ALZHEON INC.
  • ANAVEX LIFE SCIENCES CORP.
  • ANNOVIS BIO INC.
  • BIOGEN
  • BIOVIE INC.
  • EISAI CO. LTD.
  • JOHNSON & JOHNSON SERVICES INC.
  • LILLY
  • NOVO NORDISK A/S
  • TAURX PHARMACEUTICALS LTD.
List of Tables
Summary Table: Global Market for DMTs for AD, by Region, Through 2030
Table 1: Key Biomarkers Commonly Used to Evaluate and Support the Clinical Significance of AD DMTs
Table 2: Recent Late-Stage Therapeutic Candidates Failures in Clinical Trials, 2025
Table 3: DMTs Approval Status, by Country or Region, 2025
Table 4: Selected Blood Tests in Development for AD Screening/Diagnosis
Table 5: Disease-Modifying Small Molecule AD Drug Candidates in Phase 3 Clinical Trials
Table 6: Disease-Modifying Large Molecule AD Drug Candidates in Phase 3 Clinical Trials
Table 7: Global Market for DMTs for AD, by Target Type, Through 2030
Table 8: Commercially Available Anti-Amyloid Drugs
Table 9: Global Market for DMTs for AD, by Drug, Through 2030
Table 10: Small Molecule versus Large Molecule Drugs
Table 11: Global Market for DMTs for AD, by Drug Molecule Type, Through 2030
Table 12: Global Market for DMTs for AD, by Region, Through 2030
Table 13: Notable Companies Developing AD DMTs, 2025
Table 14: Abbreviations Used in the Report
Table 15: Alzheon Inc.: Company Snapshot
Table 16: Alzheon Inc.: Product Portfolio
Table 17: Alzheon Inc.: News/Key Developments, 2024
Table 18: Anavex Life Sciences Corp.: Company Snapshot
Table 19: Anavex Life Sciences Corp.: Financial Performance, FY 2023 and 2024
Table 20: Anavex Life Sciences Corp.: Product Portfolio
Table 21: Anavex Life Sciences Corp.: News/Key Developments, 2024
Table 22: Annovis Bio Inc.: Company Snapshot
Table 23: Annovis Bio Inc.: Financial Performance, FY 2023 and 2024
Table 24: Annovis Bio Inc.: Product Portfolio
Table 25: Biogen: Company Snapshot
Table 26: Biogen: Financial Performance, FY 2023 and 2024
Table 27: Biogen: Product Portfolio
Table 28: Biogen: News/Key Developments, 2024 and 2025
Table 29: BioVie Inc.: Company Snapshot
Table 30: BioVie Inc.: Financial Performance, FY 2022 and 2023
Table 31: BioVie Inc.: Product Portfolio
Table 32: Eisai Co. Ltd.: Company Snapshot
Table 33: Eisai Co. Ltd.: Financial Performance, FY 2023 and 2024
Table 34: Eisai Co. Ltd.: Product Portfolio
Table 35: Eisai Co. Ltd.: News/Key Developments, 2023-2025
Table 36: Johnson & Johnson Services Inc.: Company Snapshot
Table 37: Johnson & Johnson Services Inc.: Financial Performance, FY 2023 and 2024
Table 38: Johnson & Johnson Services Inc.: Product Portfolio
Table 39: Johnson & Johnson Services Inc.: News/Key Developments, 2024
Table 40: Lilly: Company Snapshot
Table 41: Lilly: Financial Performance, FY 2023 and 2024
Table 42: Lilly: Product Portfolio
Table 43: Lilly: News/Key Developments, 2024
Table 44: Novo Nordisk A/S: Company Snapshot
Table 45: Novo Nordisk A/S: Financial Performance, FY 2023 and 2024
Table 46: Novo Nordisk A/S: Product Portfolio
Table 47: TauRx Pharmaceuticals Ltd.: Company Snapshot
Table 48: TauRx Pharmaceuticals Ltd.: Product Portfolio
Table 49: TauRx Pharmaceuticals Ltd.: News/Key Developments, 2024
List of Figures
Summary Figure: Global Market Shares for DMTs for AD, by Region, 2024
Figure 1: Disease-Modifying Therapies (DMTs) Market Snapshot for Alzheimer’s Disease
Figure 2: People Living with Dementia Around the World, 2020-2050
Figure 3: Global Market Shares of DMTs for AD, by Region, 2024
Figure 4: Global Market Shares of DMTs for AD, by Leading Companies, 2024
Figure 5: Biogen: Revenue Shares, by Business Unit, FY 2024
Figure 6: Biogen: Revenue Shares, by Country/Region, FY 2024
Figure 7: Eisai Co. Ltd.: Revenue Shares, by Business Unit, FY 2024
Figure 8: Eisai Co. Ltd.: Revenue Shares, by Country/Region, FY 2024
Figure 9: Johnson & Johnson Services Inc.: Revenue Shares, by Business Unit, FY 2024
Figure 10: Johnson & Johnson Services Inc.: Revenue Shares, by Country/Region, FY 2024
Figure 11: Lilly: Revenue Shares, by Business Unit, FY 2024
Figure 12: Lilly: Revenue Shares, by Country/Region, FY 2024
Figure 13: Novo Nordisk A/S: Revenue Shares, by Business Unit, FY 2024
Figure 14: Novo Nordisk A/S: Revenue Shares, by Country/Region, FY 2024

Executive Summary

This report provides an overview of the global and regional markets for disease-modifying therapies for Alzheimer’s disease. It includes global revenue ($ million) for base year data of 2024, estimates for 2025, and CAGR forecasts through 2030.

Currently, the disease-modifying therapies (DMTs) market for Alzheimer’s disease (AD) is in its early stage of development, as the first DMT for AD (lecanemab) was granted full approval by the U.S. FDA in July 2023. Several DMTs are in late-stage (phase 2 and above) clinical trials. If approved, they can expand the AD DMTs market significantly. The publisher estimates market data for 2024 (the base year) and forecasts values for 2025 through 2030. Other than the approved products, the revenue forecast also considers the potential therapeutic candidates expected to enter during the forecast period and their targeted market potential.

Companies Mentioned

  • Alzheon Inc.
  • Anavex Life Sciences Corp.
  • Annovis Bio Inc.
  • Biogen
  • Biovie Inc.
  • Eisai Co. Ltd.
  • Johnson & Johnson Services Inc.
  • Lilly
  • Novo Nordisk A/S
  • Taurx Pharmaceuticals Ltd.