Bioengineered Artificial Skin Global Market Report 2025

The bioengineered artificial skin market size has grown rapidly in recent years. It will grow from $2.44 billion in 2024 to $2.75 billion in 2025 at a compound annual growth rate (CAGR) of 12.9%. The growth during the historic period can be attributed to a rise in burn injury cases, increasing prevalence of chronic wounds, early advancements in tissue engineering, growing initial government research funding, and heightened demand from military and trauma care sectors.

The bioengineered artificial skin market size is expected to see rapid growth in the next few years. It will grow to $4.43 billion in 2029 at a compound annual growth rate (CAGR) of 12.6%. The growth in the forecast period can be attributed to advancements in stem cell technologies, expanding use in cosmetic surgery, increased emphasis on personalized medicine, a growing aging population with skin conditions, and rising investments in regenerative healthcare solutions. Key trends expected during the forecast period include the integration of 3D bioprinting, the development of smart skin technologies, progress in hybrid synthetic-biological skin models, the use of artificial intelligence in tissue modeling, and enhanced collaborations between biotech companies and hospitals.

The increasing demand for cosmetic and reconstructive surgery is expected to drive growth in the bioengineered artificial skin market in the coming years. Cosmetic and reconstructive surgery involves medical procedures aimed at enhancing physical appearance or restoring the form and function of body parts affected by congenital defects, trauma, or disease. This demand is rising due to greater consumer awareness of aesthetic enhancement options and the growing need for medical restoration following injuries, congenital conditions, or illness-related deformities. Bioengineered artificial skin plays a crucial role in these surgeries by supporting tissue regeneration, minimizing scarring, and improving aesthetic results in procedures that restore or enhance damaged or missing skin. For example, in March 2023, the British Association of Aesthetic Plastic Surgeons, a UK-based non-profit organization, reported a 102% increase in cosmetic treatments performed in the UK in 2022, reaching 31,057 procedures. Therefore, the rising demand for cosmetic and reconstructive surgery is boosting the bioengineered artificial skin market.

Key companies in the bioengineered artificial skin market are focusing on technological advancements, including sophisticated tissue engineering methods, to develop highly effective skin substitutes that promote wound healing, improve patient outcomes, and meet the growing demand for regenerative medicine in treating severe burns and chronic wounds. Advanced tissue engineering integrates biology, materials science, and engineering to produce synthetic or biologically derived tissues and organs that mimic the structure and function of natural tissues for medical use. For instance, in January 2023, Urgo Group, a France-based healthcare company, launched the Genesis research laboratory dedicated to developing artificial skin to support the effective treatment of severe wounds. This initiative aims to assist healthcare professionals by creating advanced bioengineered skin solutions that accelerate recovery and enhance wound-healing outcomes.

In August 2023, Coloplast A/S, a healthcare company based in Denmark, acquired Kerecis for an undisclosed sum. This acquisition is intended to expand Coloplast’s presence in the advanced wound care market by incorporating Kerecis’ innovative fish-skin-based regenerative technology. This strengthens Coloplast’s position in biological wound care solutions and addresses the increasing global demand for effective wound healing therapies. Kerecis Limited, based in the US, produces bioengineered artificial skin substitutes derived from fish skin, specifically designed for wound healing and tissue regeneration.

Major players in the bioengineered artificial skin market are Stryker Corporation, Smith & Nephew plc, Mölnlycke Health Care AB, Integra LifeSciences Holdings Corporation, Musculoskeletal Transplant Foundation (MTF) Biologics, Organogenesis Inc., MiMedx Group Inc., Vericel Corporation, AlloSource Inc., Kerecis Inc., PolyNovo Limited, Avita Medical Inc., Cook Biotech Incorporated, Amarantus BioScience Holdings Inc., Tissue Regenix Group plc, Episkin SA, TissUse GmbH, RenovaCare Inc., NeuEsse Inc., and PolarityTE Inc.

North America was the largest region in the bioengineered artificial skin market in 2024. Asia-Pacific is expected to be the fastest-growing region in the forecast period. The regions covered in bioengineered artificial skin report are Asia-Pacific, Western Europe, Eastern Europe, North America, South America, Middle East and Africa.

The countries covered in the bioengineered artificial skin market report are Australia, Brazil, China, France, Germany, India, Indonesia, Japan, Russia, South Korea, UK, USA, Canada, Italy, Spain.

The bioengineered artificial skin market consists of revenues earned by entities by providing services such as customization and design services, clinical trial and regulatory support services, and post-implantation monitoring. The market value includes the value of related goods sold by the service provider or included within the service offering. The bioengineered artificial skin market also includes sales of integra dermal regeneration template, primatrix, pico system, and advanced wound care products. Values in this market are ‘factory gate’ values, that is the value of goods sold by the manufacturers or creators of the goods, whether to other entities (including downstream manufacturers, wholesalers, distributors and retailers) or directly to end customers. The value of goods in this market includes related services sold by the creators of the goods.

Bioengineered artificial skin is a lab-produced substitute designed to replicate the structure and function of natural human skin. It is created using living cells combined with synthetic or natural materials to imitate the skin’s layers, mainly the epidermis and dermis. This artificial skin is employed in wound healing, burn care, skin grafting, and pharmaceutical or cosmetic testing. By encouraging cell proliferation and tissue regeneration, it provides an important option when the body’s natural skin healing is inadequate or unavailable.

The primary types of bioengineered artificial skin include acellular dermal matrices, cell-based skin substitutes, skin grafts, and 3D bioprinted skin. Acellular dermal matrices (ADMs) are biological scaffolds sourced from human or animal skin, with all cellular material removed, leaving a structural framework composed of proteins such as collagen and elastin. The materials used include collagen-based, hyaluronic acid-based, silicone-based, and polyurethane-based types, while the technologies applied involve bioprinting, electrospinning, self-assembly, and microfabrication. These products find applications in burn treatment, chronic wound management, surgical reconstruction, and more, and are utilized by a range of end users including hospitals, dermatology clinics, ambulatory surgical centers, and research organizations.

The bioengineered artificial skin market research report is one of a series of new reports that provides bioengineered artificial skin market statistics, including the bioengineered artificial skin industry's global market size, regional shares, competitors with the bioengineered artificial skin market share, detailed bioengineered artificial skin market segments, market trends and opportunities, and any further data you may need to thrive in the bioengineered artificial skin market. This bioengineered artificial skin market research report delivers a complete perspective of everything you need, with an in-depth analysis of the current and future scenarios of the industry.

The market value is defined as the revenues that enterprises gain from the sale of goods and/or services within the specified market and geography through sales, grants, or donations in terms of the currency (in USD, unless otherwise specified).

The revenues for a specified geography are consumption values that are revenues generated by organizations in the specified geography within the market, irrespective of where they are produced. It does not include revenues from resales along the supply chain, either further along the supply chain or as part of other products.

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