Medical Grade Liquid Nitrogen Global Market Report 2025

The medical grade liquid nitrogen market size has grown strongly in recent years. It will grow from $2.34 billion in 2024 to $2.5 billion in 2025 at a compound annual growth rate (CAGR) of 6.8%. The growth during the historic period can be attributed to the rising demand for cryopreservation in biobanking, an increase in minimally invasive surgical procedures, expanded use in dermatological treatments, the growth of the food processing industry, and demand from electronics manufacturing.

The medical grade liquid nitrogen market size is expected to see strong growth in the next few years. It will grow to $3.23 billion in 2029 at a compound annual growth rate (CAGR) of 6.6%. The projected growth in the forecast period is expected due to rising investments in healthcare infrastructure, increased adoption of cryotherapy for cancer treatments, advancements in stem cell and regenerative medicine research, broader use in pharmaceutical cold chain logistics, and expanding applications in veterinary medicine. Key trends anticipated during this period include technological progress in storage and transportation systems, growing interest in personalized medicine, increased use of liquid nitrogen in cosmetic treatments, a stronger focus on sustainability and safe handling, and the integration of artificial intelligence (AI) and automation in cryogenic technologies.

The growing demand for cryopreservation and cryosurgery in the medical sector is expected to drive the expansion of the medical-grade liquid nitrogen market. These applications involve using extremely low temperatures, primarily through liquid nitrogen, to preserve biological materials or to treat medical conditions by freezing and removing abnormal tissues. The increased use of cryopreservation and cryosurgery is linked to their role in fertility treatments and stem cell banking, with more individuals choosing to preserve reproductive and stem cells for future use due to medical conditions, personal choices, or advancements in regenerative medicine. Medical-grade liquid nitrogen supports these applications by offering a high-purity cryogenic solution essential for maintaining biological viability and enabling precise cryosurgical interventions. For example, in June 2024, Vitality Pro, a UK-based health and wellness company, reported that around 500 individuals globally have undergone cryonic preservation, with another 4,000 registered for future procedures, indicating growing interest in this emerging technology. Consequently, rising demand in cryopreservation and cryosurgery is fueling the growth of the medical-grade liquid nitrogen market.

Leading companies in the medical-grade liquid nitrogen market are introducing cutting-edge technologies such as liquid nitrogen cryotherapy devices to address chronic respiratory conditions through minimally invasive treatments. These devices utilize extremely cold liquid nitrogen to freeze and eliminate abnormal or damaged tissue, serving therapeutic purposes such as treating warts, precancerous lesions, and skin conditions. For instance, in July 2024, CSA Medical Inc., a US-based medical device manufacturer, completed patient enrollment in its SPRAY-CB trial for the RejuvenAir System, an innovative cryotherapy device. This system delivers targeted liquid nitrogen spray to treat chronic bronchitis by applying cold temperatures to damaged lung cells. The outpatient procedure promotes regenerative healing without causing scarring and represents a significant advancement in chronic obstructive pulmonary disease (COPD) treatment by addressing mucus overproduction and airway damage.

In November 2022, VS Carbonics Inc., a US-based liquid nitrogen distributor, acquired InCryo Systems Inc. for an undisclosed sum. The acquisition was intended to broaden VS Carbonics’ capabilities in cryogenic technologies and reinforce its presence in the medical and biomedical sectors by leveraging InCryo Systems’ expertise in cryogenic system design, equipment installation, and management. InCryo Systems specializes in developing and maintaining cryogenic systems.

Major players in the medical grade liquid nitrogen market are Linde Gas & Equipment Inc., Air Liquide Healthcare, Air Products and Chemicals Inc., Airgas Inc., Nippon Sanso Holdings Corporation, Matheson Tri-Gas Inc., Gruppo SIAD, Gulf Cryo, AMCS Corporation, Red Ball Oxygen, MVS Engineering Pvt. Ltd., Coregas Pty Ltd., Kansal Industrial Gases, Stirling Cryogenics, CalOx Inc., US Gas, N-Two Medical Inc., Nitrogen Express, Cryogen (part of the Antares Alliance), Abhijit Enterprises.

North America was the largest region in the medical grade liquid nitrogen market in 2024. Asia-Pacific is expected to be the fastest-growing region in the forecast period. The regions covered in medical grade liquid nitrogen report are Asia-Pacific, Western Europe, Eastern Europe, North America, South America, Middle East and Africa.

The countries covered in the medical grade liquid nitrogen market report are Australia, Brazil, China, France, Germany, India, Indonesia, Japan, Russia, South Korea, UK, USA, Canada, Italy, Spain.

Medical-grade liquid nitrogen is a highly purified cryogenic liquid produced under stringent industry standards to ensure its safety and effectiveness in medical environments. It is widely utilized in healthcare procedures such as cryotherapy for treating skin disorders, cryopreservation for storing biological specimens such as blood and reproductive cells, and as a cooling medium in surgical and research settings. Its manufacturing and distribution involve rigorous quality control measures, guaranteeing full traceability and adherence to regulatory standards to safeguard patient health.

The primary types of medical-grade liquid nitrogen are categorized by purity levels below 99%, between 99% and 99.9%, and above 99.9%. Liquid nitrogen with a purity below 99% is generated by liquefying nitrogen gas at extremely low temperatures and is suitable for specific medical uses such as cryotherapy and tissue preservation. These products are stored in various container formats including dewar flasks, pressurized cylinders, storage tanks, portable cryogenic containers, and bulk liquid nitrogen tanks. Distribution channels include direct sales, online platforms, medical supply distributors, retail pharmacies, and specialized medical suppliers. They are applied in areas such as cryopreservation, cryosurgery, medical laboratories, pharmaceutical processes, and dermatological treatments. End users include hospitals and clinics, biotechnology and pharmaceutical companies, research laboratories, and other healthcare facilities.

The medical grade liquid nitrogen market research report is one of a series of new reports that provides medical grade liquid nitrogen market statistics, including medical grade liquid nitrogen industry global market size, regional shares, competitors with a medical grade liquid nitrogen market share, detailed medical grade liquid nitrogen market segments, market trends and opportunities, and any further data you may need to thrive in the medical grade liquid nitrogen industry. This medical grade liquid nitrogen market research report delivers a complete perspective of everything you need, with an in-depth analysis of the current and future scenario of the industry.

The medical grade liquid nitrogen market consists of sales of products such as cryogenic storage tanks, liquid nitrogen dewars, delivery systems, and associated safety equipment. Values in this market are ‘factory gate’ values, that is the value of goods sold by the manufacturers or creators of the goods, whether to other entities (including downstream manufacturers, wholesalers, distributors and retailers) or directly to end customers. The value of goods in this market includes related services sold by the creators of the goods.

The market value is defined as the revenues that enterprises gain from the sale of goods and/or services within the specified market and geography through sales, grants, or donations in terms of the currency (in USD, unless otherwise specified).

The revenues for a specified geography are consumption values that are revenues generated by organizations in the specified geography within the market, irrespective of where they are produced. It does not include revenues from resales along the supply chain, either further along the supply chain or as part of other products.

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