Bone Regeneration Material Global Market Report 2025

The bone regeneration material market size has grown strongly in recent years. It will grow from $3.76 billion in 2024 to $4.13 billion in 2025 at a compound annual growth rate (CAGR) of 9.8%. The growth observed during the historical period can be attributed to factors such as the aging global population, a rise in trauma and accident cases, greater use of dental implants, the expansion of hospital infrastructure, and an increased reliance on allografts and xenografts.

The bone regeneration material market size is expected to see strong growth in the next few years. It will grow to $5.97 billion in 2029 at a compound annual growth rate (CAGR) of 9.7%. The growth in the forecast period is expected to be driven by the growing demand for minimally invasive surgeries, the introduction of 3D-printed bone grafts, the rise of medical tourism, the increase in robotic and AI-assisted surgeries, and supportive reimbursement policies. Key trends anticipated for the forecast period include advancements in 3D bioprinting, a continued shift toward minimally invasive procedures, strategic collaborations and mergers & acquisitions, the development of personalized bone grafting solutions, and a focus on sustainability and ethical sourcing.

The rising prevalence of bone-related disorders is expected to drive the growth of the bone regeneration material market. These disorders, which affect the bones, include conditions such as osteoporosis, osteoarthritis, and bone cancer, leading to pain, fractures, and reduced mobility. The prevalence of such conditions is increasing, particularly due to the aging population, as older individuals are more prone to diseases such as osteoporosis and osteoarthritis. Bone regeneration materials play a crucial role in treating these conditions by encouraging natural bone growth, restoring strength, and improving recovery, especially in cases of fractures and osteoporosis. For example, in April 2022, the National Institutes of Health reported that in the UK, approximately 549,000 fragility fractures occur each year, including 105,000 hip fractures, 86,000 vertebral fractures, and 358,000 other types. As the population ages, the number of fragility fractures is expected to rise by 19.6% by 2030. Therefore, the increasing incidence of bone-related disorders is driving the market for bone regeneration materials.

Leading companies in the bone regeneration material market are focusing on developing innovative solutions such as synthetic bone graft substitutes to improve bone healing and regeneration. A synthetic bone graft substitute is an artificial material designed to replace or repair damaged bone tissue, promoting healing in medical procedures. For example, in May 2023, Royal Biologics, a U.S.-based medical device company, launched Bio-Reign 3D, an advanced bone graft substitute made from a hyper-crosslinked carbohydrate polymer. This material creates a highly porous 3D matrix to support bone regeneration, offering moldability, compressibility, and the ability to be sutured to prevent graft migration. Bio-Reign 3D is radiolucent upon implantation for clear imaging and turns radiopaque as new bone forms, allowing real-time monitoring of the healing process. Its biodegradation rate is aligned with natural bone formation, ensuring it is gradually replaced by healthy bone tissue.

In June 2023, Biocomposites, a UK-based medical device company, acquired Artoss GmbH to strengthen its bone regeneration portfolio. This acquisition enables Biocomposites to incorporate the proprietary NanoBone technology, enhancing its offerings to assist surgeons in treating patients with bone regeneration needs. Additionally, it expands the global reach of Artoss' innovative bone graft substitutes through Biocomposites' well-established distribution network. Artoss GmbH, based in Germany, specializes in manufacturing synthetic bone graft materials that aid in bone healing and growth.

Major players in the bone regeneration material market are Johnson & Johnson, Medtronic plc, 3M Company, Stryker Corporation, Baxter International Inc., Zimmer Biomet, Terumo Corporation, Smith & Nephew plc, Dentsply Sirona Inc., Straumann Holding AG, Integra LifeSciences Corporation, Osstem Implant, BMT Group, Septodont, Exactech Inc, LifeNet Health, Orthofix Medical Inc, Biocomposites Ltd., NuVasive Inc., Xtant Medical Holdings Inc., Kuros Biosciences AG, LASAK s.r.o, NovaBone Products LLC, Sigma Graft, B&B Dental.

North America was the largest region in the bone regeneration material market in 2024. Asia-Pacific is expected to be the fastest-growing region in the forecast period. The regions covered in bone regeneration material report are Asia-Pacific, Western Europe, Eastern Europe, North America, South America, Middle East and Africa.

The countries covered in the bone regeneration material market report are Australia, Brazil, China, France, Germany, India, Indonesia, Japan, Russia, South Korea, UK, USA, Canada, Italy, Spain.

Bone regeneration materials are bioactive substances and scaffolds created to repair or replace damaged bone by promoting cell growth and mineralization. These materials include grafts, biomimetic composites, and bioactive molecules that aim to replicate the structure and function of bone, addressing clinical needs such as defect size and healing speed.

The primary types of bone regeneration products include demineralized bone matrix (DBM), xenografts, autografts, synthetic bone grafts, bone morphogenetic protein (BMP), non-invasive electrical bone growth stimulators, and invasive electrical bone growth stimulators. Demineralized bone matrix is an allograft bone from which the mineral content has been removed, leaving behind collagen, proteins, and growth factors. These materials are made using various technologies such as 3D printing, electrospinning, sol-gel technology, and bioprinting. They are applied through surgical procedures, minimally invasive techniques, and other methods. Bone regeneration materials are used in spinal fusion, dental implants, joint reconstruction, craniomaxillofacial surgery, trauma repair, and more, and are utilized by hospitals, orthopedic clinics, dental clinics, research institutions, and other end users.

The bone regeneration material market research report is one of a series of new reports that provides bone regeneration material market statistics, including bone regeneration material industry global market size, regional shares, competitors with a bone regeneration material market share, detailed bone regeneration material market segments, market trends and opportunities, and any further data you may need to thrive in the bone regeneration material industry. This bone regeneration material market research report delivers a complete perspective of everything you need, with an in-depth analysis of the current and future scenario of the industry.

The bone regeneration material market includes sales of bone grafts, barrier membranes, scaffolds, fixation devices, bone morphogenetic proteins, and stem cell-enriched matrices. Values in this market are ‘factory gate’ values, that is, the value of goods sold by the manufacturers or creators of the goods, whether to other entities (including downstream manufacturers, wholesalers, distributors, and retailers) or directly to end customers. The value of goods in this market includes related services sold by the creators of the goods.

The market value is defined as the revenues that enterprises gain from the sale of goods and/or services within the specified market and geography through sales, grants, or donations in terms of the currency (in USD unless otherwise specified).

The revenues for a specified geography are consumption values and are revenues generated by organizations in the specified geography within the market, irrespective of where they are produced. It does not include revenues from resales along the supply chain, either further along the supply chain or as part of other products.

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