The growth in the forecast period can be attributed to growing government initiatives, increased elderly population, increasing prevalence of growth hormone deficiency, rising chronic disease prevalence, and rising number of clinical trials. Major trends in the forecast period include technological innovations, technological advancements in drug delivery systems, artificial intelligence (AI), technological innovations in drug delivery, and a shift toward pediatric treatment innovation.
The growing demand for hormone replacement therapy is expected to drive the expansion of the Skytrofa market in the future. Hormone replacement therapy (HRT) is used to replace hormones, such as estrogen and progesterone, to manage symptoms associated with menopause or hormonal imbalances. The increasing demand for HRT is largely due to an aging population and the increasing awareness of its effectiveness in alleviating menopause-related symptoms. Skytrofa is used in hormone replacement therapy to treat growth hormone deficiency by stimulating growth and development through subcutaneous injections. For example, in October 2023, the National Health Service in the UK reported that 11 million HRT prescriptions were issued during 2022-2023, reflecting a 47% increase from the previous year. Additionally, about 2.3 million patients received HRT prescriptions, marking a 29% rise compared to the previous year. This growing demand for HRT is expected to contribute to the market growth of Skytrofa.
The increase in healthcare expenditure is expected to drive the growth of the Skytrofa market as well. Healthcare expenditure refers to the total spending on medical services, treatments, and healthcare-related costs. The rise in healthcare spending is driven by the aging population and the increasing prevalence of chronic diseases, both of which require more frequent medical interventions and long-term care. Higher healthcare spending supports Skytrofa by funding research, improving treatment accessibility, and ensuring that patients with growth hormone deficiency have insurance coverage. According to The Health Foundation, in November 2024, planned day-to-day Department of Health and Social Care (DHSC) spending increased from $222.2 billion (£177.9 billion) in 2023-24 to $234.7 billion (£190.1 billion) in 2024-25, and it is projected to rise further to $249.4 billion (£200.5 billion) by 2025-26, reflecting an average annual growth rate of 3.3%. This increase in healthcare expenditure is likely to drive further growth in the Skytrofa market.
A notable trend in the Skytrofa market is the development of long-acting growth hormone formulations aimed at improving patient convenience and treatment adherence. Long-acting growth hormones are designed to be administered less frequently, such as on a weekly or monthly basis, while still maintaining their therapeutic effects, as opposed to daily injections. For instance, in September 2023, Ascendis Pharma A/S, a Denmark-based biotechnology company, launched SKYTROFA (lonapegsomatropin) in Germany. This once-weekly treatment is aimed at children and adolescents aged 3 to 18 years with growth hormone deficiency. By utilizing pegylation technology to extend the medication's half-life, this treatment only requires a single injection per week, offering a more convenient dosing schedule compared to daily therapies. This innovation is intended to enhance patient adherence, reduce the burden of frequent injections, and ultimately improve the overall quality of care for young patients.
The key company operating in the skytrofa market is Ascendis Pharma A/S
North America was the largest region in the skytrofa market in 2024. Asia-Pacific is expected to be the fastest-growing region in the forecast period. The regions covered in skytrofa report are Asia-Pacific, Western Europe, Eastern Europe, North America, South America, Middle East and Africa.The countries covered in the skytrofa market report are Australia, India, China, South Korea, Japan, UK, France, Germany, USA, Canada.
Skytrofa is a long-acting recombinant human growth hormone (rhGH) used to treat pediatric growth hormone deficiency (GHD) through weekly subcutaneous injections. It stimulates growth in children with GHD and offers a more convenient alternative to daily growth hormone treatments.
Note that the outlook for this market is being affected by rapid changes in trade relations and tariffs globally. The report will be updated prior to delivery to reflect the latest status, including revised forecasts and quantified impact analysis. The report’s Recommendations and Conclusions sections will be updated to give strategies for entities dealing with the fast-moving international environment.
The main indications for Skytrofa include growth hormone deficiency (GHD), idiopathic short stature (ISS), and Prader-Willi syndrome (PWS). GHD occurs when the pituitary gland does not produce enough growth hormone, a crucial substance for growth, cell reproduction, and regeneration. Skytrofa is available in liquid formulations for subcutaneous injection and is distributed through various channels, including hospital pharmacies, retail pharmacies, and online pharmacies. It is used by various end users, such as hospitals, clinics, ambulatory care centers, and home care settings.
The skytrofa market consists of sales of skytrofa injection devices, skytrofa diagnostic kits and pre-filled syringes. Values in this market are ‘factory gate’ values, that is, the value of goods sold by the manufacturers or creators of the goods, whether to other entities (including downstream manufacturers, wholesalers, distributors, and retailers) or directly to end customers. The value of goods in this market includes related services sold by the creators of the goods.
The market value is defined as the revenues that enterprises gain from the sale of goods and/or services within the specified market and geography through sales, grants, or donations in terms of the currency (in USD, unless otherwise specified).
The revenues for a specified geography are consumption values that are revenues generated by organizations in the specified geography within the market, irrespective of where they are produced. It does not include revenues from resales along the supply chain, either further along the supply chain or as part of other products.
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Table of Contents
Executive Summary
Skytrofa Global Market Report 2025 provides strategists, marketers and senior management with the critical information they need to assess the market.This report focuses on skytrofa market which is experiencing strong growth. The report gives a guide to the trends which will be shaping the market over the next ten years and beyond.
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Description
Where is the largest and fastest growing market for skytrofa ? How does the market relate to the overall economy, demography and other similar markets? What forces will shape the market going forward? The skytrofa market global report answers all these questions and many more.The report covers market characteristics, size and growth, segmentation, regional and country breakdowns, competitive landscape, market shares, trends and strategies for this market. It traces the market’s historic and forecast market growth by geography.
- The market characteristics section of the report defines and explains the market.
- The market size section gives the market size ($b) covering both the historic growth of the market, and forecasting its development.
- The forecasts are made after considering the major factors currently impacting the market. These include:
- The forecasts are made after considering the major factors currently impacting the market. These include the Russia-Ukraine war, rising inflation, higher interest rates, and the legacy of the COVID-19 pandemic.
- Market segmentations break down the market into sub markets.
- The regional and country breakdowns section gives an analysis of the market in each geography and the size of the market by geography and compares their historic and forecast growth. It covers the growth trajectory of COVID-19 for all regions, key developed countries and major emerging markets.
- The competitive landscape chapter gives a description of the competitive nature of the market, market shares, and a description of the leading companies. Key financial deals which have shaped the market in recent years are identified.
- The trends and strategies section analyses the shape of the market as it emerges from the crisis and suggests how companies can grow as the market recovers.
Scope
Markets Covered:
1) By Indication: Growth Hormone Deficiency (GHD); Turner Syndrome; Idiopathic Short Stature (ISS); Prader-Willi Syndrome (PWS)2) By Formulation: Liquid Formulation; Subcutaneous Injection
3) By Distribution Channel: Hospital Pharmacies; Retail Pharmacies; Online Pharmacies
4) By End User: Hospital; Clinicals; Ambulatory Care; Home Care
Key Companies Profiled: Ascendis Pharma A/S
Countries: Australia, India, China, South Korea, Japan, UK, France, Germany, USA, Canada
Regions: Asia-Pacific; Western Europe; Eastern Europe; North America; South America; Middle East; Africa
Time Series: Five years historic and ten years forecast.
Data: Ratios of market size and growth to related markets, GDP proportions, expenditure per capita.
Data Segmentation: Country and regional historic and forecast data, market share of competitors, market segments.
Sourcing and Referencing: Data and analysis throughout the report is sourced using end notes.
Delivery Format: PDF, Word and Excel Data Dashboard.
Companies Mentioned
- Ascendis Pharma A/S

